NO319372B1 - Fremgangsmate, samt diagnostiske sett for bestemmelse av toksisitet ved anvendelse av bakterielle stresspromotere fusert til reporter-gener - Google Patents
Fremgangsmate, samt diagnostiske sett for bestemmelse av toksisitet ved anvendelse av bakterielle stresspromotere fusert til reporter-gener Download PDFInfo
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- NO319372B1 NO319372B1 NO19950040A NO950040A NO319372B1 NO 319372 B1 NO319372 B1 NO 319372B1 NO 19950040 A NO19950040 A NO 19950040A NO 950040 A NO950040 A NO 950040A NO 319372 B1 NO319372 B1 NO 319372B1
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Classifications
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
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- Wood Science & Technology (AREA)
- Zoology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91079392A | 1992-07-06 | 1992-07-06 | |
| PCT/US1993/006537 WO1994001584A1 (en) | 1992-07-06 | 1993-07-06 | Methods and diagnostic kits for determining toxicity utilizing bacterial stress promoters fused to reporter genes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO950040D0 NO950040D0 (no) | 1995-01-05 |
| NO950040L NO950040L (no) | 1995-03-06 |
| NO319372B1 true NO319372B1 (no) | 2005-07-25 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| NO19950040A NO319372B1 (no) | 1992-07-06 | 1995-01-05 | Fremgangsmate, samt diagnostiske sett for bestemmelse av toksisitet ved anvendelse av bakterielle stresspromotere fusert til reporter-gener |
Country Status (15)
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|---|---|
| US (2) | US5589337A (da) |
| EP (1) | EP0651825B1 (da) |
| JP (1) | JP3456703B2 (da) |
| KR (1) | KR100300932B1 (da) |
| AT (1) | ATE162225T1 (da) |
| AU (1) | AU687353B2 (da) |
| CA (1) | CA2139667C (da) |
| DE (1) | DE69316368T2 (da) |
| DK (1) | DK0651825T3 (da) |
| ES (1) | ES2113546T3 (da) |
| GR (1) | GR3026639T3 (da) |
| HK (1) | HK1008433A1 (da) |
| NO (1) | NO319372B1 (da) |
| SG (1) | SG77101A1 (da) |
| WO (1) | WO1994001584A1 (da) |
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| IL107815A (en) * | 1992-12-04 | 2003-12-10 | Du Pont | Genetic constructs comprising a stress-responsive promoter linked to a lux reporter operon and methods of use in environmental testing |
| AU692434B2 (en) * | 1993-01-21 | 1998-06-11 | President And Fellows Of Harvard College | Methods and diagnostic kits utilizing mammalian stress promoters to determine toxicity of a compound |
| GB9420735D0 (en) * | 1994-10-14 | 1994-11-30 | Karobio Ab | Reporter cell line |
| CA2200702C (en) * | 1994-11-23 | 2000-12-05 | E.I. Du Pont De Nemours And Company | Lyophilized bioluminescent bacterial reagent for the detection of toxicants |
| US6387651B1 (en) | 1995-04-12 | 2002-05-14 | Biolog, Inc. | Comparative phenotype analysis of two or more microorganisms using a plurality of substrates within a microwell device |
| AU717755B2 (en) | 1996-01-26 | 2000-03-30 | Virco Bvba | Method of managing the chemotherapy of patients who are HIV positive based on the phenotypic drug sensitivity of human HIV strains |
| CA2267999A1 (en) * | 1996-11-15 | 1998-05-22 | E.I. Du Pont De Nemours And Company | A small volume, highly sensitive method for detecting environmental insults |
| WO1999014311A1 (en) * | 1997-09-18 | 1999-03-25 | Smithkline Beecham Corporation | Method of screening for antimicrobial compounds |
| EP0950717A1 (en) * | 1998-04-14 | 1999-10-20 | "VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK", afgekort "V.I.T.O." | Diagnostic system and method for determining the presence of a genotoxic compound in a sample |
| US6953666B1 (en) | 1998-11-06 | 2005-10-11 | Emory University | Biomarkers for oxidative stress |
| AU1243500A (en) * | 1998-11-06 | 2000-05-29 | Emory University | Biomarkers for oxidative stress |
| WO2000061796A1 (de) * | 1999-04-10 | 2000-10-19 | Merlin Gesellschaft Für Mikrobiologische Diagnostika Mbh | Verfahren zur genotypischen klassifizierung |
| US6410255B1 (en) * | 1999-05-05 | 2002-06-25 | Aurora Biosciences Corporation | Optical probes and assays |
| US6673554B1 (en) * | 1999-06-14 | 2004-01-06 | Trellie Bioinformatics, Inc. | Protein localization assays for toxicity and antidotes thereto |
| US6931396B1 (en) | 1999-06-29 | 2005-08-16 | Gene Logic Inc. | Biological data processing |
| US20030232056A1 (en) * | 1999-09-10 | 2003-12-18 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
| GB2355791B (en) * | 1999-10-28 | 2004-10-20 | Molecular Light Tech Res Ltd | Detection of mRNA expression using chemiluminescent labelled probes |
| CA2400642A1 (en) * | 2000-02-23 | 2001-08-30 | Vertex Pharmaceuticals (San Diego) Llc | Modified fluorescent proteins |
| US6696239B1 (en) | 2000-04-20 | 2004-02-24 | Biolog, Inc. | Comparative phenotype analysis for assessment of biological active compounds such as antimicrobials |
| US7020561B1 (en) | 2000-05-23 | 2006-03-28 | Gene Logic, Inc. | Methods and systems for efficient comparison, identification, processing, and importing of gene expression data |
| US20030171876A1 (en) * | 2002-03-05 | 2003-09-11 | Victor Markowitz | System and method for managing gene expression data |
| US20030009295A1 (en) * | 2001-03-14 | 2003-01-09 | Victor Markowitz | System and method for retrieving and using gene expression data from multiple sources |
| US6667153B1 (en) | 2000-06-26 | 2003-12-23 | Susan Margaret Thomas | Composition and method for detecting mutagens |
| EP1409718A2 (en) * | 2000-07-21 | 2004-04-21 | Phase-1 Molecular Toxicology | Canine toxicity genes |
| US20030119094A1 (en) * | 2001-09-24 | 2003-06-26 | Irm Llc | Solubility reporter gene constructs |
| WO2002061041A2 (en) * | 2000-11-21 | 2002-08-08 | Irm Llc | Solubility reporter gene constructs |
| AU2002237879A1 (en) * | 2001-01-23 | 2002-08-06 | Gene Logic, Inc. | A method and system for predicting the biological activity, including toxicology and toxicity, of substances |
| US7054758B2 (en) * | 2001-01-30 | 2006-05-30 | Sciona Limited | Computer-assisted means for assessing lifestyle risk factors |
| CA2437498A1 (en) * | 2001-02-05 | 2002-08-15 | Shen Quan Pan | Methods and kits for identifying scavengers of reactive oxygen species (ros) |
| US7211383B2 (en) * | 2001-04-05 | 2007-05-01 | Genelink, Inc. | Kits and methods for assessing skin health |
| US20020146698A1 (en) * | 2001-04-05 | 2002-10-10 | Genelink, Inc. | Kits and methods for assessing oxidative stress |
| US7251642B1 (en) | 2001-08-06 | 2007-07-31 | Gene Logic Inc. | Analysis engine and work space manager for use with gene expression data |
| DE20116898U1 (de) * | 2001-10-15 | 2002-01-17 | Festo Ag & Co | Mikroventil |
| KR20030040923A (ko) * | 2001-11-17 | 2003-05-23 | 광주과학기술원 | 산화적 손상과 관련된 유해성 탐지를 위한 재조합발광박테리아 대장균ＤＨ5@/ｐＳｏｄａＬｕｘ（ＥＢＨＪ1）［ＫＣＴＣ10098ＢＰ］ |
| KR100461757B1 (ko) * | 2002-06-20 | 2004-12-14 | 광주과학기술원 | 화학물질의 독성과 그 유해성을 탐지할 수 있는 재조합발광 박테리아 |
| CA2445420A1 (en) | 2003-07-29 | 2005-01-29 | Invitrogen Corporation | Kinase and phosphatase assays |
| US7727752B2 (en) | 2003-07-29 | 2010-06-01 | Life Technologies Corporation | Kinase and phosphatase assays |
| WO2005045426A2 (en) * | 2003-11-10 | 2005-05-19 | Aic | Gene expression profiling of hazardous compounds and corresponding database clustering algorithm |
| GB0415963D0 (en) * | 2004-07-16 | 2004-08-18 | Cxr Biosciences Ltd | Detection of cellular stress |
| CA2475456A1 (en) * | 2004-07-20 | 2006-01-20 | Biophys, Inc. | Method and device to optimize analyte and antibody substrate binding by least energy adsorption |
| CA2475240A1 (en) * | 2004-07-20 | 2006-01-20 | Biophys, Inc. | Method and device to measure dynamic internal calibration true dose response curves |
| WO2006096063A1 (en) * | 2005-03-11 | 2006-09-14 | Stichting Voor De Technische Wetenschappen | Construct and method for screening, selection and identification of stress factors |
| US7646450B2 (en) * | 2005-12-29 | 2010-01-12 | Lg Display Co., Ltd. | Light emitting diode array, method of manufacturing the same, backlight assembly having the same, and LCD having the same |
| ES2307395B2 (es) * | 2006-09-04 | 2009-07-09 | Universidad De Oviedo | Metodo rapido de deteccion y evaluacion de agentes genotoxicos. |
| EP2067104A1 (en) | 2006-09-28 | 2009-06-10 | Xeround Systems Ltd. | Apparatus and method for a distributed storage global database |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11739367B2 (en) | 2017-11-08 | 2023-08-29 | Twinstrand Biosciences, Inc. | Reagents and adapters for nucleic acid sequencing and methods for making such reagents and adapters |
| EP3752639A4 (en) * | 2018-02-13 | 2021-12-01 | Twinstrand Biosciences, Inc. | METHODS AND REAGENTS FOR DETECTION AND ASSESSMENT OF GENOTOXICITY |
| SG11202100141SA (en) | 2018-07-12 | 2021-02-25 | Twinstrand Biosciences Inc | Methods and reagents for characterizing genomic editing, clonal expansion, and associated applications |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0063522B1 (en) * | 1981-04-14 | 1989-07-19 | Institut Pasteur | An inducible dna replication-cell division coupling mechanism in escherichia coli |
| FR2533584B1 (fr) * | 1982-09-28 | 1986-03-21 | Pasteur Institut | Procede de detection du pouvoir mutagene de substances, susceptibles d'induire la deterioration d'adn cellulaires, mettant en jeu la production d'une reponse sos |
| US4569916A (en) * | 1984-05-21 | 1986-02-11 | Massachusetts Institute Of Technology | Assay for tumor promoting agents |
| EP0370813A3 (en) * | 1988-11-25 | 1991-06-19 | Exemplar Corporation | Rapid screening mutagenesis and teratogenesis assay |
| KR920701453A (ko) * | 1989-03-17 | 1992-08-11 | 미리엄 디. 멕코나헤이 | 유전자발현의 외부조절 |
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1993
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- 1993-07-06 SG SG1996001688A patent/SG77101A1/en unknown
- 1993-07-06 ES ES93917113T patent/ES2113546T3/es not_active Expired - Lifetime
- 1993-07-06 JP JP50356294A patent/JP3456703B2/ja not_active Expired - Lifetime
- 1993-07-06 CA CA002139667A patent/CA2139667C/en not_active Expired - Lifetime
- 1993-07-06 DE DE69316368T patent/DE69316368T2/de not_active Expired - Lifetime
- 1993-07-06 EP EP93917113A patent/EP0651825B1/en not_active Expired - Lifetime
- 1993-07-06 KR KR1019950700038A patent/KR100300932B1/ko not_active IP Right Cessation
- 1993-07-06 AT AT93917113T patent/ATE162225T1/de not_active IP Right Cessation
- 1993-07-06 AU AU45884/93A patent/AU687353B2/en not_active Expired
- 1993-07-06 DK DK93917113T patent/DK0651825T3/da active
- 1993-07-06 US US08/367,122 patent/US5589337A/en not_active Expired - Lifetime
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1994
- 1994-04-21 US US08/231,990 patent/US5585232A/en not_active Expired - Lifetime
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1995
- 1995-01-05 NO NO19950040A patent/NO319372B1/no not_active IP Right Cessation
-
1998
- 1998-04-14 GR GR980400840T patent/GR3026639T3/el unknown
- 1998-07-14 HK HK98109159A patent/HK1008433A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO950040L (no) | 1995-03-06 |
| KR950702639A (ko) | 1995-07-29 |
| JP3456703B2 (ja) | 2003-10-14 |
| JPH08501930A (ja) | 1996-03-05 |
| CA2139667C (en) | 2005-03-29 |
| CA2139667A1 (en) | 1994-01-20 |
| WO1994001584A1 (en) | 1994-01-20 |
| AU687353B2 (en) | 1998-02-26 |
| ES2113546T3 (es) | 1998-05-01 |
| KR100300932B1 (ko) | 2001-10-22 |
| SG77101A1 (en) | 2000-12-19 |
| US5585232A (en) | 1996-12-17 |
| DE69316368T2 (de) | 1998-06-25 |
| DE69316368D1 (de) | 1998-02-19 |
| EP0651825B1 (en) | 1998-01-14 |
| EP0651825A1 (en) | 1995-05-10 |
| US5589337A (en) | 1996-12-31 |
| DK0651825T3 (da) | 1998-09-14 |
| HK1008433A1 (en) | 1999-05-07 |
| ATE162225T1 (de) | 1998-01-15 |
| GR3026639T3 (en) | 1998-07-31 |
| NO950040D0 (no) | 1995-01-05 |
| AU4588493A (en) | 1994-01-31 |
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