NO317837B1 - Anvendelse av forbindelse for fremstilling av et medikament for a inhibere et aspartylproteaseavhengig virus - Google Patents
Anvendelse av forbindelse for fremstilling av et medikament for a inhibere et aspartylproteaseavhengig virus Download PDFInfo
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- NO317837B1 NO317837B1 NO19982556A NO982556A NO317837B1 NO 317837 B1 NO317837 B1 NO 317837B1 NO 19982556 A NO19982556 A NO 19982556A NO 982556 A NO982556 A NO 982556A NO 317837 B1 NO317837 B1 NO 317837B1
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- compound
- hiv
- formula
- inhibiting
- drug
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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- A—HUMAN NECESSITIES
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- AIDS & HIV (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/567,199 US5646180A (en) | 1995-12-05 | 1995-12-05 | Treatment of the CNS effects of HIV |
| PCT/US1996/019447 WO1997020554A1 (en) | 1995-12-05 | 1996-12-05 | Treatment of the cns effects of hiv with vx-478, alone or in combination with azt or 3tc |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO982556L NO982556L (no) | 1998-06-04 |
| NO982556D0 NO982556D0 (no) | 1998-06-04 |
| NO317837B1 true NO317837B1 (no) | 2004-12-20 |
Family
ID=24266147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19982556A NO317837B1 (no) | 1995-12-05 | 1998-06-04 | Anvendelse av forbindelse for fremstilling av et medikament for a inhibere et aspartylproteaseavhengig virus |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5646180A (ru) |
| EP (1) | EP0866696B1 (ru) |
| JP (1) | JP2000501713A (ru) |
| KR (1) | KR19990071750A (ru) |
| CN (1) | CN1203530A (ru) |
| AP (1) | AP864A (ru) |
| AT (1) | ATE279922T1 (ru) |
| AU (1) | AU722850B2 (ru) |
| BR (1) | BR9611861A (ru) |
| CA (1) | CA2238471A1 (ru) |
| CZ (1) | CZ291994B6 (ru) |
| DE (1) | DE69633680T2 (ru) |
| ES (1) | ES2231828T3 (ru) |
| HU (1) | HUP9903673A3 (ru) |
| NO (1) | NO317837B1 (ru) |
| NZ (1) | NZ324603A (ru) |
| OA (1) | OA10691A (ru) |
| PL (1) | PL187747B1 (ru) |
| PT (1) | PT866696E (ru) |
| RU (1) | RU2203658C2 (ru) |
| UA (1) | UA61902C2 (ru) |
| WO (1) | WO1997020554A1 (ru) |
| ZA (1) | ZA9610139B (ru) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6107499A (en) * | 1988-02-26 | 2000-08-22 | Neuromedica, Inc. | Dopamine analog amide |
| US5942253A (en) | 1995-10-12 | 1999-08-24 | Immunex Corporation | Prolonged release of GM-CSF |
| US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
| US6576636B2 (en) * | 1996-05-22 | 2003-06-10 | Protarga, Inc. | Method of treating a liver disorder with fatty acid-antiviral agent conjugates |
| PL330747A1 (en) * | 1996-06-25 | 1999-05-24 | Glaxo Group Ltd | Vx478, zidovudin, ftc and/or 3tc containing combinations for use in treating hiv infections |
| IL127350A0 (en) * | 1996-06-25 | 1999-10-28 | Glaxo Group Ltd | Combinations comprising VX478 zidovudine and/or 1592U89 for use in the treatment of HIV |
| ZA9710071B (en) * | 1996-11-21 | 1998-05-25 | Abbott Lab | Pharmaceutical composition. |
| US6232333B1 (en) | 1996-11-21 | 2001-05-15 | Abbott Laboratories | Pharmaceutical composition |
| BR9809124A (pt) * | 1997-05-17 | 2000-08-01 | Glaxo Group Ltd | Combinação, formulação, farmacêutica, processo para o tratamento de uma infecção por hiv em um animal, infectado, uso de (-)-(1s, 4r)-4-[2-amino-6-(ciclopropilamino)-9h-purin-9-il)-2-cicl openteno-1-metanol, e, pacote de paciente |
| WO1998057648A1 (en) * | 1997-06-16 | 1998-12-23 | Vertex Pharmaceuticals Incorporated | Methods of increasing the bioavailability of stable crystal polymorphs of a compound |
| US6576231B2 (en) * | 1997-09-12 | 2003-06-10 | Schering Ag | Methods for treating HIV-Infected Patients by the Administration of GM-CSF and a protease inhibitor |
| US6197764B1 (en) | 1997-11-26 | 2001-03-06 | Protarga, Inc. | Clozapine compositions and uses thereof |
| US6153653A (en) * | 1997-11-26 | 2000-11-28 | Protarga, Inc. | Choline compositions and uses thereof |
| US5977174A (en) * | 1997-11-26 | 1999-11-02 | Neuromedica, Inc. | Cholinergic compositions and uses thereof |
| US5955459A (en) * | 1997-11-26 | 1999-09-21 | Neuromedica, Inc. | Fatty acid-antipsychotic compositions and uses thereof |
| US6436989B1 (en) | 1997-12-24 | 2002-08-20 | Vertex Pharmaceuticals, Incorporated | Prodrugs of aspartyl protease inhibitors |
| US6309632B1 (en) * | 1998-04-28 | 2001-10-30 | Immunex Corporation | Methods for treating HIV-infected patients by administering GM-CSF |
| US6875773B1 (en) * | 1998-05-29 | 2005-04-05 | Ben M. Dunn | Combination therapy for treatment of FIV infection |
| US20090197827A1 (en) * | 1998-05-29 | 2009-08-06 | Dunn Ben M | Combination Therapy for Treatment of FIV Infection |
| US7235583B1 (en) * | 1999-03-09 | 2007-06-26 | Luitpold Pharmaceuticals, Inc., | Fatty acid-anticancer conjugates and uses thereof |
| US6417189B1 (en) | 1999-11-12 | 2002-07-09 | Gpi Nil Holdings, Inc. | AZA compounds, pharmaceutical compositions and methods of use |
| CA2424305A1 (en) * | 2000-10-16 | 2002-04-25 | Conor Medsystems, Inc. | Expandable medical device for delivery of beneficial agent |
| AU2002303164A1 (en) | 2001-03-23 | 2002-10-08 | Protarga, Inc. | Fatty amine drug conjugates |
| AU2002305099A1 (en) * | 2001-03-23 | 2002-10-08 | Protarga, Inc. | Fatty alcohol drug conjugates |
| JP4625637B2 (ja) | 2002-02-22 | 2011-02-02 | シャイア エルエルシー | 活性物質送達系及び活性物質を保護し投与する方法 |
| PL216369B1 (pl) | 2004-07-27 | 2014-03-31 | Gilead Sciences | Pochodne fosfonianowe, kompozycje farmaceutyczne zawierające te pochodne oraz zastosowanie tych pochodnych do wytwarzania leku do hamowania wirusa HIV |
| CA2594910A1 (en) * | 2005-01-20 | 2006-07-27 | University Of Rochester | Compositions and methods relating to mitochondrial hyperpolarization in neurological disease |
| WO2007076372A2 (en) * | 2005-12-23 | 2007-07-05 | University Of Rochester | Treatment of neuroaids using inhibitors of glycogen synthase kinase (gsk)-3 |
| UY30295A1 (es) * | 2006-04-19 | 2007-11-30 | Abbott Gmbh & Amp | Compuestos heterociclicos apropiados para tratar trastornos que responden a la modulacion del receptor de serotonina 5ht6 |
| UY32306A (es) | 2008-12-09 | 2010-07-30 | Gilead Sciences Inc | Derivados de pteridinona y pirimidinodiazepinona y composiciones farmacéuticas que modulan en forma selectiva los receptores tipo toll, métodos y usos |
| US20110223131A1 (en) | 2010-02-24 | 2011-09-15 | Gilead Sciences, Inc. | Antiviral compounds |
| CN106232073B (zh) | 2014-02-28 | 2020-11-03 | 阿坦斯医疗保健产品公司 | 具有多层折叠吸收芯的吸收性用品 |
| WO2016001907A1 (en) | 2014-07-02 | 2016-01-07 | Prendergast Patrick T | Mogroside iv and mogroside v as agonist/stimulator/un-blocking agent for toll-like receptor 4 and adjuvant for use in human/animal vaccine and to stimulate immunity against disease agents. |
| TWI806081B (zh) | 2014-07-11 | 2023-06-21 | 美商基利科學股份有限公司 | 用於治療HIV之toll樣受體調節劑 |
| EP3349757A1 (en) | 2015-09-15 | 2018-07-25 | Gilead Sciences, Inc. | Modulators of toll-like recptors for the treatment of hiv |
| EP3801424A1 (en) | 2018-05-28 | 2021-04-14 | Attends Healthcare Products, Inc. | Dryness layer laminate for absorbent articles |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IS2334B (is) * | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
| WO1994013629A1 (en) * | 1992-12-11 | 1994-06-23 | Vertex Pharmaceuticals Incorporated | Mannitol derivatives and their use as inhibitors of aspartyl protease |
-
1995
- 1995-12-05 US US08/567,199 patent/US5646180A/en not_active Expired - Lifetime
-
1996
- 1996-05-12 UA UA98073527A patent/UA61902C2/uk unknown
- 1996-12-03 ZA ZA9610139A patent/ZA9610139B/xx unknown
- 1996-12-05 BR BR9611861A patent/BR9611861A/pt not_active Application Discontinuation
- 1996-12-05 KR KR1019980704028A patent/KR19990071750A/ko not_active Application Discontinuation
- 1996-12-05 AT AT96942917T patent/ATE279922T1/de not_active IP Right Cessation
- 1996-12-05 AP APAP/P/1998/001340A patent/AP864A/en active
- 1996-12-05 CN CN96198816A patent/CN1203530A/zh active Pending
- 1996-12-05 JP JP9521449A patent/JP2000501713A/ja active Pending
- 1996-12-05 HU HU9903673A patent/HUP9903673A3/hu unknown
- 1996-12-05 EP EP96942917A patent/EP0866696B1/en not_active Expired - Lifetime
- 1996-12-05 WO PCT/US1996/019447 patent/WO1997020554A1/en active IP Right Grant
- 1996-12-05 RU RU98112594/14A patent/RU2203658C2/ru not_active IP Right Cessation
- 1996-12-05 AU AU11486/97A patent/AU722850B2/en not_active Ceased
- 1996-12-05 PT PT96942917T patent/PT866696E/pt unknown
- 1996-12-05 NZ NZ324603A patent/NZ324603A/xx unknown
- 1996-12-05 PL PL96327061A patent/PL187747B1/pl not_active IP Right Cessation
- 1996-12-05 CZ CZ19981708A patent/CZ291994B6/cs not_active IP Right Cessation
- 1996-12-05 ES ES96942917T patent/ES2231828T3/es not_active Expired - Lifetime
- 1996-12-05 DE DE69633680T patent/DE69633680T2/de not_active Expired - Fee Related
- 1996-12-05 CA CA002238471A patent/CA2238471A1/en not_active Abandoned
-
1998
- 1998-05-29 OA OA9800067A patent/OA10691A/en unknown
- 1998-06-04 NO NO19982556A patent/NO317837B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2203658C2 (ru) | 2003-05-10 |
| ES2231828T3 (es) | 2005-05-16 |
| CZ291994B6 (cs) | 2003-07-16 |
| EP0866696A1 (en) | 1998-09-30 |
| US5646180A (en) | 1997-07-08 |
| CZ170898A3 (cs) | 1998-09-16 |
| EP0866696B1 (en) | 2004-10-20 |
| PT866696E (pt) | 2005-03-31 |
| DE69633680D1 (de) | 2004-11-25 |
| ATE279922T1 (de) | 2004-11-15 |
| AP9801340A0 (en) | 1998-09-30 |
| NO982556L (no) | 1998-06-04 |
| CA2238471A1 (en) | 1997-06-12 |
| JP2000501713A (ja) | 2000-02-15 |
| BR9611861A (pt) | 1999-05-18 |
| NZ324603A (en) | 2000-08-25 |
| HUP9903673A3 (en) | 2000-08-28 |
| WO1997020554A1 (en) | 1997-06-12 |
| OA10691A (en) | 2001-05-04 |
| HUP9903673A2 (hu) | 2000-03-28 |
| CN1203530A (zh) | 1998-12-30 |
| NO982556D0 (no) | 1998-06-04 |
| PL327061A1 (en) | 1998-11-23 |
| KR19990071750A (ko) | 1999-09-27 |
| ZA9610139B (en) | 1997-06-17 |
| AU1148697A (en) | 1997-06-27 |
| AU722850B2 (en) | 2000-08-10 |
| AP864A (en) | 2000-08-11 |
| UA61902C2 (en) | 2003-12-15 |
| DE69633680T2 (de) | 2006-02-23 |
| PL187747B1 (pl) | 2004-09-30 |
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