NO315966B1 - Pulverformulering inneholdende melezitose som et fortynningsmiddel, fremgangsmåter for dens fremstilling, og anvendelse derav - Google Patents
Pulverformulering inneholdende melezitose som et fortynningsmiddel, fremgangsmåter for dens fremstilling, og anvendelse derav Download PDFInfo
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- NO315966B1 NO315966B1 NO19972660A NO972660A NO315966B1 NO 315966 B1 NO315966 B1 NO 315966B1 NO 19972660 A NO19972660 A NO 19972660A NO 972660 A NO972660 A NO 972660A NO 315966 B1 NO315966 B1 NO 315966B1
- Authority
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- Norway
- Prior art keywords
- powder formulation
- formulation according
- powder
- melezitose
- polypeptide
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- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9404468A SE9404468D0 (sv) | 1994-12-22 | 1994-12-22 | Powder formulations |
| PCT/SE1995/001541 WO1996019207A1 (en) | 1994-12-22 | 1995-12-19 | Powder formulations containing melezitose as a diluent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO972660D0 NO972660D0 (no) | 1997-06-10 |
| NO972660L NO972660L (no) | 1997-06-10 |
| NO315966B1 true NO315966B1 (no) | 2003-11-24 |
Family
ID=20396435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19972660A NO315966B1 (no) | 1994-12-22 | 1997-06-10 | Pulverformulering inneholdende melezitose som et fortynningsmiddel, fremgangsmåter for dens fremstilling, og anvendelse derav |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6004574A (de) |
| EP (2) | EP1224929B1 (de) |
| JP (1) | JPH10510828A (de) |
| KR (1) | KR100391873B1 (de) |
| CN (1) | CN1080114C (de) |
| AR (1) | AR002261A1 (de) |
| AT (2) | ATE220900T1 (de) |
| AU (1) | AU702898B2 (de) |
| BR (1) | BR9510422A (de) |
| CA (1) | CA2206803A1 (de) |
| CZ (1) | CZ288487B6 (de) |
| DE (2) | DE69533294T2 (de) |
| DK (2) | DK0799030T3 (de) |
| EE (1) | EE03381B1 (de) |
| ES (2) | ES2222306T3 (de) |
| FI (1) | FI972654A (de) |
| HK (1) | HK1003619A1 (de) |
| HU (1) | HU217975B (de) |
| IL (1) | IL116459A (de) |
| IS (1) | IS1848B (de) |
| MY (1) | MY114211A (de) |
| NO (1) | NO315966B1 (de) |
| NZ (1) | NZ298168A (de) |
| PL (1) | PL183944B1 (de) |
| PT (2) | PT1224929E (de) |
| RU (1) | RU2144819C1 (de) |
| SA (1) | SA95160484B1 (de) |
| SE (1) | SE9404468D0 (de) |
| SK (1) | SK283147B6 (de) |
| TR (1) | TR199501632A1 (de) |
| TW (1) | TW474823B (de) |
| UA (1) | UA44757C2 (de) |
| WO (1) | WO1996019207A1 (de) |
| ZA (1) | ZA9510753B (de) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830853A (en) | 1994-06-23 | 1998-11-03 | Astra Aktiebolag | Systemic administration of a therapeutic preparation |
| TW402506B (en) * | 1993-06-24 | 2000-08-21 | Astra Ab | Therapeutic preparation for inhalation |
| US6794357B1 (en) | 1993-06-24 | 2004-09-21 | Astrazeneca Ab | Compositions for inhalation |
| US6632456B1 (en) * | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
| US6524557B1 (en) * | 1994-12-22 | 2003-02-25 | Astrazeneca Ab | Aerosol formulations of peptides and proteins |
| EE9700138A (et) * | 1994-12-22 | 1997-12-15 | Astra Aktiebolag | Aerosoolravimvormid |
| US6043214A (en) * | 1997-03-20 | 2000-03-28 | Novo Nordisk A/S | Method for producing powder formulation comprising an insulin |
| US5898028A (en) * | 1997-03-20 | 1999-04-27 | Novo Nordisk A/S | Method for producing powder formulation comprising an insulin |
| ATE219942T1 (de) * | 1997-03-20 | 2002-07-15 | Novo Nordisk As | Therapeutische pulverformulierung zur pulmonaren anwendung, welche kristallines insulin enthält |
| WO2000061178A1 (en) * | 1999-04-13 | 2000-10-19 | Inhale Therapeutics Systems, Inc. | Pulmonary administration of dry powder formulations for treating infertility |
| EP1169053A1 (de) | 1999-04-13 | 2002-01-09 | Inhale Therapeutic Systems, Inc. | Verabreichung von trockenpulverformulierungen über die lungen zur behandlung der unfruchtbarkeit |
| GB0011807D0 (en) * | 2000-05-16 | 2000-07-05 | Quadrant Holdings Cambridge | Formulation for inhalation |
| JP2004515467A (ja) | 2000-08-07 | 2004-05-27 | ネクター セラピューティックス | 吸入可能な、噴霧乾燥した、最少の凝集物を有する４−ヘリックスバンドルタンパク質粉末 |
| US6828297B2 (en) | 2001-06-04 | 2004-12-07 | Nobex Corporation | Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
| US6828305B2 (en) | 2001-06-04 | 2004-12-07 | Nobex Corporation | Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
| US6713452B2 (en) | 2001-06-04 | 2004-03-30 | Nobex Corporation | Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
| US7713932B2 (en) | 2001-06-04 | 2010-05-11 | Biocon Limited | Calcitonin drug-oligomer conjugates, and uses thereof |
| US6835802B2 (en) | 2001-06-04 | 2004-12-28 | Nobex Corporation | Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties |
| US6770625B2 (en) | 2001-09-07 | 2004-08-03 | Nobex Corporation | Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith |
| US7030082B2 (en) * | 2001-09-07 | 2006-04-18 | Nobex Corporation | Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith |
| AU2002366267B2 (en) | 2001-11-19 | 2007-05-10 | Becton, Dickinson And Company | Pharmaceutical compositions in particulate form |
| SE0200657D0 (sv) * | 2002-03-04 | 2002-03-04 | Astrazeneca Ab | Novel Formulation |
| AU2005269753B2 (en) | 2004-07-19 | 2011-08-18 | Biocon Limited | Insulin-oligomer conjugates, formulations and uses thereof |
| EP2457580A1 (de) * | 2004-08-25 | 2012-05-30 | The UAB Research Foundation | Absorptionsverbesserer zur Arzneimittelverabreichung |
| US20140162965A1 (en) | 2004-08-25 | 2014-06-12 | Aegis Therapeutics, Inc. | Compositions for oral drug administration |
| US20090047347A1 (en) * | 2005-07-29 | 2009-02-19 | Aegis Therapeutics, Inc. | Compositions for Drug Administration |
| US8268791B2 (en) * | 2004-08-25 | 2012-09-18 | Aegis Therapeutics, Llc. | Alkylglycoside compositions for drug administration |
| US20060046962A1 (en) | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Absorption enhancers for drug administration |
| US9895444B2 (en) | 2004-08-25 | 2018-02-20 | Aegis Therapeutics, Llc | Compositions for drug administration |
| US8226949B2 (en) | 2006-06-23 | 2012-07-24 | Aegis Therapeutics Llc | Stabilizing alkylglycoside compositions and methods thereof |
| PT2203181T (pt) | 2007-10-16 | 2018-05-10 | Biocon Ltd | Uma composição farmacêutica sólida para administração por via oral e o seu processo de fabrico |
| EP2271347B1 (de) | 2008-03-28 | 2016-05-11 | Hale Biopharma Ventures, Llc | Verabreichung von benzodiazepin-zusammensetzungen |
| CN101618023B (zh) * | 2008-06-30 | 2011-11-30 | 江苏先声药物研究有限公司 | 一种制备微粉化蛋白的方法 |
| US8440631B2 (en) | 2008-12-22 | 2013-05-14 | Aegis Therapeutics, Llc | Compositions for drug administration |
| DK2947148T3 (en) | 2010-04-20 | 2017-09-18 | Octapharma Ag | NEW STABILIZER FOR PHARMACEUTICAL PROTEINS |
| ES2917973T3 (es) | 2011-06-14 | 2022-07-12 | Neurelis Inc | Administración de benzodiacepina |
| US9480966B2 (en) * | 2012-04-30 | 2016-11-01 | General Electric Company | Substrates and methods for collection, stabilization and elution of biomolecules |
| WO2015146849A1 (ja) * | 2014-03-25 | 2015-10-01 | 国立大学法人香川大学 | 希少糖を有効成分とするマラリア伝播阻止剤およびマラリア原虫の発育阻害剤 |
| AU2015284355A1 (en) * | 2014-06-30 | 2017-02-02 | Tate & Lyle Ingredients Americas Llc | Coating compositions for consumable articles |
| EP3212212B1 (de) | 2014-10-31 | 2020-09-23 | Monash University | Puderzubereitung |
| FI4035762T3 (fi) | 2015-09-09 | 2023-12-04 | Drawbridge Health Inc | Laitteita näytteiden keräämistä, stabilointia ja säilytystä varten |
| JP6941224B2 (ja) | 2018-02-06 | 2021-09-29 | イージス セラピューティクス，エルエルシー | 疾患の処置のための鼻腔内エピネフリン製剤及び方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE556587A (de) * | 1957-01-31 | 1957-04-11 | ||
| GB1144905A (en) * | 1965-03-25 | 1969-03-12 | Fisons Pharmaceuticals Ltd | Substituted bis-(2-carboxy-chromonyl-oxy) derivatives and preparation and pharmaceutical compositions thereof |
| DE2750090A1 (de) * | 1976-11-19 | 1978-06-01 | Sandoz Ag | Neue verabreichungsformen fuer organische verbindungen |
| SE7812207L (sv) * | 1977-12-01 | 1979-06-02 | Welsh Nat School Med | Apparat, forfarande och framstellda produkter for anvendning vid administration av antihistaminer |
| JPS6034925B2 (ja) * | 1979-07-31 | 1985-08-12 | 帝人株式会社 | 持続性鼻腔用製剤およびその製造法 |
| JPS59163313A (ja) * | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
| DE3326089A1 (de) * | 1983-07-20 | 1985-02-07 | Gödecke AG, 1000 Berlin | Zur inhalation bestimmte darreichungsform von calcium-antagonisten |
| JPS61267528A (ja) * | 1984-11-26 | 1986-11-27 | Yamanouchi Pharmaceut Co Ltd | 吸収促進剤を含有するカルシトニン経鼻剤 |
| AU587472B2 (en) * | 1985-05-22 | 1989-08-17 | Liposome Technology, Inc. | Liposome inhalation method and system |
| IT1204826B (it) * | 1986-03-04 | 1989-03-10 | Chiesi Farma Spa | Composizioni farmaceutiche per inalazione |
| NZ222907A (en) * | 1986-12-16 | 1990-08-28 | Novo Industri As | Preparation for intranasal administration containing a phospholipid absorption enhancing system |
| US5179079A (en) * | 1986-12-16 | 1993-01-12 | Novo Nordisk A/S | Nasal formulation and intranasal administration therewith |
| EP0360340A1 (de) * | 1988-09-19 | 1990-03-28 | Akzo N.V. | Peptidenthaltende Zubereitung zur intranasalen Verabreichung |
| JPH02104531A (ja) * | 1988-10-14 | 1990-04-17 | Toyo Jozo Co Ltd | 経鼻投与用生理活性ペプチド組成物 |
| US5011678A (en) * | 1989-02-01 | 1991-04-30 | California Biotechnology Inc. | Composition and method for administration of pharmaceutically active substances |
| US5176132A (en) * | 1989-05-31 | 1993-01-05 | Fisons Plc | Medicament inhalation device and formulation |
| JP2642486B2 (ja) * | 1989-08-04 | 1997-08-20 | 田辺製薬株式会社 | 難溶性薬物の超微粒子化法 |
| JPH05963A (ja) * | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| GB9010742D0 (en) * | 1990-05-14 | 1990-07-04 | Quadrant Bioresources Ltd | Stabilization of biological macromolecular substances |
| CA2082951C (en) * | 1991-03-15 | 1999-12-21 | Robert M. Platz | Pulmonary administration of granulocyte colony stimulating factor |
| EP0621774B1 (de) * | 1992-01-21 | 1996-12-18 | Sri International | Verbessertes verfahren zur herstellung von mikronisierter polypeptidarzneimitteln |
| EP0679088B1 (de) * | 1992-09-29 | 2002-07-10 | Inhale Therapeutic Systems | Pulmonale abgabe von aktiven fragmenten des parathormons |
| TW402506B (en) * | 1993-06-24 | 2000-08-21 | Astra Ab | Therapeutic preparation for inhalation |
| IS1796B (is) * | 1993-06-24 | 2001-12-31 | Ab Astra | Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband |
| US5506203C1 (en) * | 1993-06-24 | 2001-02-06 | Astra Ab | Systemic administration of a therapeutic preparation |
-
1994
- 1994-12-22 SE SE9404468A patent/SE9404468D0/xx unknown
-
1995
- 1995-12-18 ZA ZA9510753A patent/ZA9510753B/xx unknown
- 1995-12-19 ES ES01130870T patent/ES2222306T3/es not_active Expired - Lifetime
- 1995-12-19 HU HU9800493A patent/HU217975B/hu not_active IP Right Cessation
- 1995-12-19 MY MYPI95003942A patent/MY114211A/en unknown
- 1995-12-19 EP EP01130870A patent/EP1224929B1/de not_active Expired - Lifetime
- 1995-12-19 DK DK95942342T patent/DK0799030T3/da active
- 1995-12-19 PL PL95320751A patent/PL183944B1/pl not_active IP Right Cessation
- 1995-12-19 EP EP95942342A patent/EP0799030B1/de not_active Expired - Lifetime
- 1995-12-19 BR BR9510422A patent/BR9510422A/pt not_active Application Discontinuation
- 1995-12-19 DE DE69533294T patent/DE69533294T2/de not_active Expired - Fee Related
- 1995-12-19 AU AU43592/96A patent/AU702898B2/en not_active Ceased
- 1995-12-19 PT PT01130870T patent/PT1224929E/pt unknown
- 1995-12-19 RU RU97112496A patent/RU2144819C1/ru not_active IP Right Cessation
- 1995-12-19 IL IL11645995A patent/IL116459A/en not_active IP Right Cessation
- 1995-12-19 CA CA002206803A patent/CA2206803A1/en not_active Abandoned
- 1995-12-19 JP JP8519731A patent/JPH10510828A/ja active Pending
- 1995-12-19 CN CN95196965A patent/CN1080114C/zh not_active Expired - Fee Related
- 1995-12-19 US US08/617,753 patent/US6004574A/en not_active Expired - Fee Related
- 1995-12-19 WO PCT/SE1995/001541 patent/WO1996019207A1/en active IP Right Grant
- 1995-12-19 AT AT95942342T patent/ATE220900T1/de not_active IP Right Cessation
- 1995-12-19 NZ NZ298168A patent/NZ298168A/en unknown
- 1995-12-19 AT AT01130870T patent/ATE271382T1/de not_active IP Right Cessation
- 1995-12-19 EE EE9700135A patent/EE03381B1/xx not_active IP Right Cessation
- 1995-12-19 SK SK812-97A patent/SK283147B6/sk unknown
- 1995-12-19 PT PT95942342T patent/PT799030E/pt unknown
- 1995-12-19 KR KR1019970704254A patent/KR100391873B1/ko not_active IP Right Cessation
- 1995-12-19 DK DK01130870T patent/DK1224929T3/da active
- 1995-12-19 UA UA97073876A patent/UA44757C2/uk unknown
- 1995-12-19 ES ES95942342T patent/ES2177674T3/es not_active Expired - Lifetime
- 1995-12-19 CZ CZ19971946A patent/CZ288487B6/cs not_active IP Right Cessation
- 1995-12-19 TW TW084113557A patent/TW474823B/zh not_active IP Right Cessation
- 1995-12-19 DE DE69527542T patent/DE69527542T2/de not_active Expired - Fee Related
- 1995-12-21 AR ARP950100706A patent/AR002261A1/es active IP Right Grant
- 1995-12-21 TR TR95/01632A patent/TR199501632A1/xx unknown
- 1995-12-30 SA SA95160484A patent/SA95160484B1/ar unknown
-
1997
- 1997-06-03 IS IS4495A patent/IS1848B/is unknown
- 1997-06-10 NO NO19972660A patent/NO315966B1/no unknown
- 1997-06-19 FI FI972654A patent/FI972654A/fi unknown
-
1998
- 1998-04-02 HK HK98102788A patent/HK1003619A1/xx not_active IP Right Cessation
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