EE03381B1 - Pulbrilised ravimvormid, mis sisaldavad lahjendajana melesitoosi - Google Patents

Pulbrilised ravimvormid, mis sisaldavad lahjendajana melesitoosi

Info

Publication number
EE03381B1
EE03381B1 EE9700135A EE9700135A EE03381B1 EE 03381 B1 EE03381 B1 EE 03381B1 EE 9700135 A EE9700135 A EE 9700135A EE 9700135 A EE9700135 A EE 9700135A EE 03381 B1 EE03381 B1 EE 03381B1
Authority
EE
Estonia
Prior art keywords
diluent
formulations containing
powder formulations
containing melezitose
melezitose
Prior art date
Application number
EE9700135A
Other languages
English (en)
Estonian (et)
Other versions
EE9700135A (et
Inventor
B�ckstr�m Kjell
Johansson Ann
Linden Helena
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of EE9700135A publication Critical patent/EE9700135A/xx
Publication of EE03381B1 publication Critical patent/EE03381B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
EE9700135A 1994-12-22 1995-12-19 Pulbrilised ravimvormid, mis sisaldavad lahjendajana melesitoosi EE03381B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9404468A SE9404468D0 (sv) 1994-12-22 1994-12-22 Powder formulations
PCT/SE1995/001541 WO1996019207A1 (en) 1994-12-22 1995-12-19 Powder formulations containing melezitose as a diluent

Publications (2)

Publication Number Publication Date
EE9700135A EE9700135A (et) 1997-12-15
EE03381B1 true EE03381B1 (et) 2001-04-16

Family

ID=20396435

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700135A EE03381B1 (et) 1994-12-22 1995-12-19 Pulbrilised ravimvormid, mis sisaldavad lahjendajana melesitoosi

Country Status (34)

Country Link
US (1) US6004574A (de)
EP (2) EP1224929B1 (de)
JP (1) JPH10510828A (de)
KR (1) KR100391873B1 (de)
CN (1) CN1080114C (de)
AR (1) AR002261A1 (de)
AT (2) ATE220900T1 (de)
AU (1) AU702898B2 (de)
BR (1) BR9510422A (de)
CA (1) CA2206803A1 (de)
CZ (1) CZ288487B6 (de)
DE (2) DE69533294T2 (de)
DK (2) DK0799030T3 (de)
EE (1) EE03381B1 (de)
ES (2) ES2222306T3 (de)
FI (1) FI972654A (de)
HK (1) HK1003619A1 (de)
HU (1) HU217975B (de)
IL (1) IL116459A (de)
IS (1) IS1848B (de)
MY (1) MY114211A (de)
NO (1) NO315966B1 (de)
NZ (1) NZ298168A (de)
PL (1) PL183944B1 (de)
PT (2) PT1224929E (de)
RU (1) RU2144819C1 (de)
SA (1) SA95160484B1 (de)
SE (1) SE9404468D0 (de)
SK (1) SK283147B6 (de)
TR (1) TR199501632A1 (de)
TW (1) TW474823B (de)
UA (1) UA44757C2 (de)
WO (1) WO1996019207A1 (de)
ZA (1) ZA9510753B (de)

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EE9700138A (et) * 1994-12-22 1997-12-15 Astra Aktiebolag Aerosoolravimvormid
US6043214A (en) * 1997-03-20 2000-03-28 Novo Nordisk A/S Method for producing powder formulation comprising an insulin
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US8268791B2 (en) * 2004-08-25 2012-09-18 Aegis Therapeutics, Llc. Alkylglycoside compositions for drug administration
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US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
US8226949B2 (en) 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
PT2203181T (pt) 2007-10-16 2018-05-10 Biocon Ltd Uma composição farmacêutica sólida para administração por via oral e o seu processo de fabrico
EP2271347B1 (de) 2008-03-28 2016-05-11 Hale Biopharma Ventures, Llc Verabreichung von benzodiazepin-zusammensetzungen
CN101618023B (zh) * 2008-06-30 2011-11-30 江苏先声药物研究有限公司 一种制备微粉化蛋白的方法
US8440631B2 (en) 2008-12-22 2013-05-14 Aegis Therapeutics, Llc Compositions for drug administration
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Also Published As

Publication number Publication date
AR002261A1 (es) 1998-03-11
NO972660D0 (no) 1997-06-10
DE69527542T2 (de) 2003-01-30
PT1224929E (pt) 2004-10-29
MX9704551A (es) 1997-10-31
PL183944B1 (pl) 2002-08-30
ZA9510753B (en) 1996-06-24
EP0799030A1 (de) 1997-10-08
EP0799030B1 (de) 2002-07-24
CZ288487B6 (en) 2001-06-13
ES2177674T3 (es) 2002-12-16
ATE271382T1 (de) 2004-08-15
JPH10510828A (ja) 1998-10-20
CN1080114C (zh) 2002-03-06
IL116459A (en) 2002-11-10
DK0799030T3 (da) 2002-09-16
IS1848B (is) 2003-02-07
UA44757C2 (uk) 2002-03-15
BR9510422A (pt) 1998-07-07
AU702898B2 (en) 1999-03-11
TR199501632A1 (tr) 1997-03-21
WO1996019207A1 (en) 1996-06-27
HU217975B (hu) 2000-05-28
TW474823B (en) 2002-02-01
ES2222306T3 (es) 2005-02-01
PL320751A1 (en) 1997-10-27
KR100391873B1 (ko) 2003-10-17
ATE220900T1 (de) 2002-08-15
NZ298168A (en) 1999-08-30
CN1171049A (zh) 1998-01-21
FI972654A0 (fi) 1997-06-19
DE69533294D1 (de) 2004-08-26
EE9700135A (et) 1997-12-15
HK1003619A1 (en) 1998-11-06
NO972660L (no) 1997-06-10
CA2206803A1 (en) 1996-06-27
SK81297A3 (en) 1997-11-05
NO315966B1 (no) 2003-11-24
SK283147B6 (sk) 2003-03-04
MY114211A (en) 2002-08-30
DE69527542D1 (de) 2002-08-29
RU2144819C1 (ru) 2000-01-27
EP1224929B1 (de) 2004-07-21
HUT77648A (hu) 1998-07-28
DK1224929T3 (da) 2004-10-04
CZ194697A3 (en) 1997-10-15
US6004574A (en) 1999-12-21
IS4495A (is) 1997-06-03
EP1224929A2 (de) 2002-07-24
SA95160484B1 (ar) 2005-10-01
FI972654A (fi) 1997-06-19
DE69533294T2 (de) 2005-05-19
PT799030E (pt) 2002-11-29
IL116459A0 (en) 1996-03-31
EP1224929A3 (de) 2002-12-18
SE9404468D0 (sv) 1994-12-22
AU4359296A (en) 1996-07-10

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