NO314550B1 - Fremgangsmåte for fremstilling av et mutant herpesvirus - Google Patents
Fremgangsmåte for fremstilling av et mutant herpesvirus Download PDFInfo
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- NO314550B1 NO314550B1 NO19931057A NO931057A NO314550B1 NO 314550 B1 NO314550 B1 NO 314550B1 NO 19931057 A NO19931057 A NO 19931057A NO 931057 A NO931057 A NO 931057A NO 314550 B1 NO314550 B1 NO 314550B1
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- virus
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- expression system
- mutant
- corresponding expression
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2710/16011—Herpesviridae
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- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
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- C12N2710/00011—Details
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- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16661—Methods of inactivation or attenuation
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- General Engineering & Computer Science (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| GB909020799A GB9020799D0 (en) | 1990-09-25 | 1990-09-25 | Viral vaccines |
| GB919104903A GB9104903D0 (en) | 1991-03-08 | 1991-03-08 | Viral vaccines |
| PCT/GB1991/001632 WO1992005263A1 (en) | 1990-09-25 | 1991-09-23 | Viral defective vaccine produced by transcomplementing cell line |
Publications (3)
| Publication Number | Publication Date |
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| NO931057D0 NO931057D0 (no) | 1993-03-23 |
| NO931057L NO931057L (no) | 1993-05-03 |
| NO314550B1 true NO314550B1 (no) | 2003-04-07 |
Family
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Family Applications (1)
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| NO19931057A NO314550B1 (no) | 1990-09-25 | 1993-03-23 | Fremgangsmåte for fremstilling av et mutant herpesvirus |
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| JP (1) | JP3895366B2 (da) |
| KR (1) | KR100372934B1 (da) |
| AT (1) | ATE194657T1 (da) |
| AU (1) | AU658836B2 (da) |
| BR (1) | BR9106879A (da) |
| CA (1) | CA2091678C (da) |
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| GR (1) | GR3034484T3 (da) |
| HK (1) | HK1001656A1 (da) |
| MX (1) | MX9203717A (da) |
| NO (1) | NO314550B1 (da) |
| OA (1) | OA09777A (da) |
| WO (1) | WO1992005263A1 (da) |
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| DE10399031I1 (de) * | 1987-08-28 | 2004-01-29 | Health Research Inc | Rekombinante Viren. |
| CH682669A5 (fr) * | 1989-03-08 | 1993-10-29 | Health Research Inc | Virus recombinant modifié pour exprimer un produit de gènes chez un hôte, procédés et vaccin correspondants. |
| DE69132311T2 (de) | 1990-09-25 | 2000-12-14 | Cantab Pharmaceuticals Research Ltd., Cambridge | Bei einer transkomplementenden zellinie erzeugter defektiver virenimpfstoff |
| US5665362A (en) * | 1990-09-25 | 1997-09-09 | Cantab Pharmaceuticals Research Limited | Viral vaccines |
| US5837261A (en) * | 1990-09-25 | 1998-11-17 | Cantab Pharmaceuticals Research Limited | Viral vaccines |
| US7374768B1 (en) | 1990-09-25 | 2008-05-20 | Xenova Research Limited | Viral vaccines |
| EP0561034B1 (en) * | 1991-08-26 | 1999-06-09 | IMMUNO Aktiengesellschaft | Direct molecular cloning of a modified chordopox virus genome |
| TW289731B (da) * | 1992-07-09 | 1996-11-01 | Akzo Nv | |
| JPH07500972A (ja) * | 1992-07-30 | 1995-02-02 | アクゾ・ノベル・エヌ・ベー | 非放出性ヘルペスウイルス生ワクチン |
| US7223411B1 (en) | 1992-07-31 | 2007-05-29 | Dana-Farber Cancer Institute | Herpesvirus replication defective mutants |
| ATE228008T1 (de) * | 1992-07-31 | 2002-12-15 | Harvard College | Herpesvirus impfstoffe |
| CA2158148A1 (en) * | 1993-03-19 | 1994-09-29 | Stephen Charles Inglis | Defective mutant non-retroviral virus (e.g. hsv) as vaccine |
| WO1995003399A2 (en) * | 1993-07-19 | 1995-02-02 | Cantab Pharmaceuticals Research Limited | Production method for preparation of disabled viruses |
| AU7263994A (en) * | 1993-08-06 | 1995-02-28 | Kai Juhani Ernst Krohn | Novel mutated human and simian immunodeficiency viruses and vaccines containing said viruses |
| EP0659885A1 (en) * | 1993-12-21 | 1995-06-28 | Akzo Nobel N.V. | Vaccine against viruses associated with antibody-dependent-enhancement of viral infectivity |
| ES2243937T3 (es) * | 1994-04-29 | 2005-12-01 | Baxter Healthcare S.A. | Poxvirus recombinados en regiones esenciales con la ayuda de polinucleotidos extraños. |
| US6156319A (en) | 1994-07-25 | 2000-12-05 | The Trustees Of The University Of Pennsylvania | Soluble herpesvirus glycoprotein complex vaccine |
| US5807557A (en) * | 1994-07-25 | 1998-09-15 | The Trustees Of The University Of Pennsylvania | Soluble herpesvirus glycoprotein complex |
| GB9415369D0 (en) * | 1994-07-29 | 1994-09-21 | Lynxvale Ltd | Mutant virus |
| GB9415319D0 (en) * | 1994-07-29 | 1994-09-21 | Medical Res Council | HSV viral vector |
| GB9423663D0 (en) * | 1994-11-23 | 1995-01-11 | Cantab Pharma Res | Viral preparations, immunogens, and vaccines |
| WO1996026267A1 (en) * | 1995-02-21 | 1996-08-29 | Cantab Pharmaceuticals Research Limited | Viral preparations, vectors, immunogens, and vaccines |
| EP0871755A1 (en) * | 1995-03-23 | 1998-10-21 | Cantab Pharmaceuticals Research Limited | Vectors for gene delivery |
| EP0828823A4 (en) * | 1995-06-01 | 1999-02-10 | Merck & Co Inc | HERPES SIMPLEX TYPE 1 VIRUS PROTEASE MUTANTS AND VECTORS THEREOF |
| JPH11513565A (ja) * | 1995-10-19 | 1999-11-24 | セント ジュード チルドレンズ リサーチ ホスピタル | ヘルペスウィルスベクター及びその利用 |
| DE19709148C1 (de) * | 1997-03-06 | 1998-09-03 | Evotec Biosystems Gmbh | Verfahren zur Herstellung eines Impfstoffes gegen infektiöse Erreger |
| IL132323A0 (en) | 1997-04-28 | 2001-03-19 | Rhone Poulenc Rorer Sa | Adenovirus-mediated intratumoral delivery of an angiogenesis antagonist for the treatment of tumors |
| EP0884382A3 (en) * | 1997-06-10 | 2000-10-25 | Pfizer Products Inc. | Processes for preparation of marek's disease virus using continuous mammalian cell lines |
| US6875606B1 (en) | 1997-10-23 | 2005-04-05 | The United States Of America As Represented By The Department Of Veterans Affairs | Human α-7 nicotinic receptor promoter |
| GB9804632D0 (en) | 1998-03-05 | 1998-04-29 | Cantab Pharma Res | Virus preparations and methods |
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| US6225456B1 (en) | 1998-05-07 | 2001-05-01 | University Technololy Corporation | Ras suppressor SUR-5 |
| US6506889B1 (en) | 1998-05-19 | 2003-01-14 | University Technology Corporation | Ras suppressor SUR-8 and related compositions and methods |
| US6399354B1 (en) | 1998-07-31 | 2002-06-04 | President And Fellows Of Harvard College | Replication-competent virus expressing a detectable fusion protein |
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| US6573090B1 (en) | 1998-12-09 | 2003-06-03 | The General Hospital Corporation | Enhanced packaging of herpes virus amplicons and generation of recombinant virus vectors |
| US6441156B1 (en) | 1998-12-30 | 2002-08-27 | The United States Of America As Represented By The Department Of Health And Human Services | Calcium channel compositions and methods of use thereof |
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| GB0018307D0 (en) | 2000-07-26 | 2000-09-13 | Aventis Pharm Prod Inc | Polypeptides |
| EP2264072A1 (en) | 2000-04-13 | 2010-12-22 | The Rockefeller University | Enhancement of antibody-mediated cytotoxicity. |
| ES2609494T3 (es) | 2000-05-10 | 2017-04-20 | Mayo Foundation For Medical Education And Research | Anticuerpos IgM humanos con la capacidad de inducir remielinización y usos diagnósticos y terapéuticos de los mismos, particularmente en el sistema nervioso central |
| WO2002022649A2 (en) | 2000-09-14 | 2002-03-21 | Mount Sinai School Of Medicine | Screening methods to identify g-proteins and other compounds which modulate phosphodiesterase (pde) activity |
| US7060442B2 (en) | 2000-10-30 | 2006-06-13 | Regents Of The University Of Michigan | Modulators on Nod2 signaling |
| AU2002227450B2 (en) | 2000-12-28 | 2008-02-28 | Wyeth | Recombinant protective protein from $I(streptococcus pneumoniae) |
| CN1610556A (zh) | 2001-03-02 | 2005-04-27 | 洛克菲勒大学 | 保留天然变应原的免疫原性并具减弱的变应原性的重组杂合变应原构建体 |
| US7803982B2 (en) | 2001-04-20 | 2010-09-28 | The Mount Sinai School Of Medicine Of New York University | T1R3 transgenic animals, cells and related methods |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| US7785608B2 (en) | 2002-08-30 | 2010-08-31 | Wyeth Holdings Corporation | Immunogenic compositions for the prevention and treatment of meningococcal disease |
| US7432057B2 (en) | 2004-01-30 | 2008-10-07 | Michigan State University | Genetic test for PSE-susceptible turkeys |
| GB0408164D0 (en) | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
| GB0716992D0 (en) * | 2007-08-31 | 2007-10-10 | Immune Targeting Systems Its L | Influenza antigen delivery vectors and constructs |
| US7604798B2 (en) | 2004-07-15 | 2009-10-20 | Northwestern University | Methods and compositions for importing nucleic acids into cell nuclei |
| EP1784416B1 (en) | 2004-07-16 | 2011-10-05 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Vaccines against aids comprising cmv/r nucleic acid constructs |
| GB2421025A (en) * | 2004-12-09 | 2006-06-14 | Oxxon Therapeutics Ltd | HSV vaccination vectors |
| US7439327B2 (en) | 2005-01-18 | 2008-10-21 | Nuvelo, Inc. | Stem cell factor-like proteins and uses thereof |
| US8088382B2 (en) | 2005-07-05 | 2012-01-03 | Cornell Research Foundation, Inc. | Methods of inhibiting transendothelial migration of neutrophils and monocytes with anti-CD99L2 antibodies |
| US20100008944A1 (en) * | 2005-07-29 | 2010-01-14 | President And Fellows Of Harvard College | Herpes simplex virus mutant and uses therefore |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| US8093043B2 (en) | 2008-06-04 | 2012-01-10 | New York University | β-TrCP1, β-TrCP2 and RSK1 or RSK2 inhibitors and methods for sensitizing target cells to apoptosis |
| EP2303318A2 (en) | 2008-06-20 | 2011-04-06 | Wyeth LLC | Compositions and methods of use of orf1358 from beta-hemolytic streptococcal strains |
| WO2009155535A2 (en) | 2008-06-20 | 2009-12-23 | Duke University | Compositions, methods and kits for eliciting an immune response |
| AU2009313615B2 (en) | 2008-11-05 | 2012-11-29 | Regents Of The University Of Minnesota | Multicomponent immunogenic composition for the prevention of beta-hemolytic streptococcal (BHS) disease |
| WO2010096561A1 (en) | 2009-02-18 | 2010-08-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Synthetic hiv/siv gag proteins and uses thereof |
| WO2011116351A2 (en) | 2010-03-19 | 2011-09-22 | University Of South Alabama | Methods and compositions for the treatment of cancer |
| SI3246044T2 (sl) | 2010-08-23 | 2024-06-28 | Wyeth Llc | Stabilne formulacije antigenov neisseria meningitidis RLP2086 |
| CA2809758C (en) | 2010-09-10 | 2021-07-13 | Wyeth Llc | Non-lipidated variants of neisseria meningitidis orf2086 antigens |
| US9458456B2 (en) | 2011-04-01 | 2016-10-04 | University Of South Alabama | Methods and compositions for the diagnosis, classification, and treatment of cancer |
| AU2012267786B2 (en) | 2011-06-10 | 2017-08-03 | Oregon Health & Science University | CMV glycoproteins and recombinant vectors |
| US9464291B2 (en) | 2012-01-06 | 2016-10-11 | University Of South Alabama | Methods and compositions for the treatment of cancer |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| MX359256B (es) | 2012-03-09 | 2018-09-19 | Pfizer | Composiciones de neisseria meningitidis y metodos de las mismas. |
| EP2964665B1 (en) | 2013-03-08 | 2018-08-01 | Pfizer Inc | Immunogenic fusion polypeptides |
| WO2014164703A1 (en) | 2013-03-11 | 2014-10-09 | University Of Florida Research Foundation, Inc. | Delivery of card protein as therapy for occular inflammation |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| EP3888675A1 (en) | 2013-09-24 | 2021-10-06 | Duke University | Compositions, methods and kits for eliciting an immune response |
| BE1023557B1 (fr) | 2014-02-10 | 2017-05-03 | Univercells Sa | Systeme, appareil et procede pour la production de biomolecules |
| EP3107939B1 (en) | 2014-02-19 | 2020-06-17 | University of Florida Research Foundation, Inc. | Delivery of nrf2 as therapy for protection against reactive oxygen species |
| AU2016221318B2 (en) | 2015-02-19 | 2020-06-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| IL267733B2 (en) | 2017-01-31 | 2023-10-01 | Pfizer | NEISSERIA MENINGITIDIS preparations and methods therefor |
| KR20200003921A (ko) | 2017-05-15 | 2020-01-10 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정한 바이러스-함유 조성물 |
| WO2018211419A1 (en) | 2017-05-15 | 2018-11-22 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
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| US5338683A (en) * | 1981-12-24 | 1994-08-16 | Health Research Incorporated | Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins |
| EP0213894A3 (en) * | 1985-08-23 | 1987-10-21 | Advanced Genetics Research Institute | Defective viral particle vaccines and methods for their use |
| US4996152A (en) * | 1987-12-04 | 1991-02-26 | The United States Of America, As Represented By The Secretary Of Agriculture | Avian herpesvirus amplicon as a eucaryotic expression vector |
| JPH03504079A (ja) * | 1988-03-21 | 1991-09-12 | カイロン コーポレイション | 組換えレトロウィルス |
| IL92298A (en) * | 1988-11-14 | 2001-04-30 | Us Secretary U S Dept Of Comme | Method for producing isolated empty b19 parvovirus capsids, introducing genes into cells utilizing the same, diagnostic assays for detecting parvovirus infection and an anti-parvovirus vaccine containing said capsids |
| JP3140757B2 (ja) * | 1989-02-06 | 2001-03-05 | デイナ・フアーバー・キヤンサー・インステイテユート | パッケージング欠陥ｈｉｖプロウイルス、細胞系及びその使用 |
| CH682669A5 (fr) | 1989-03-08 | 1993-10-29 | Health Research Inc | Virus recombinant modifié pour exprimer un produit de gènes chez un hôte, procédés et vaccin correspondants. |
| FR2663228A2 (fr) * | 1989-09-29 | 1991-12-20 | Agronomique Inst Nat Rech | Composition immunisante contre la maladie de newcastle et procede de preparation. |
| CA2039921A1 (en) * | 1990-04-16 | 1991-10-17 | Xandra O. Breakefield | Transfer and expression of gene sequences into central nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication |
| DE69132311T2 (de) | 1990-09-25 | 2000-12-14 | Cantab Pharmaceuticals Research Ltd., Cambridge | Bei einer transkomplementenden zellinie erzeugter defektiver virenimpfstoff |
| ATE247163T1 (de) * | 1991-03-07 | 2003-08-15 | Virogenetics Corp | Gentechnologisch hergestellter stamm für impfstoffe |
| ATE228008T1 (de) | 1992-07-31 | 2002-12-15 | Harvard College | Herpesvirus impfstoffe |
-
1991
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- 1991-09-23 ES ES91917033T patent/ES2150416T3/es not_active Expired - Lifetime
- 1991-09-23 AU AU86489/91A patent/AU658836B2/en not_active Ceased
- 1991-09-23 DK DK91917033T patent/DK0550553T3/da active
- 1991-09-23 BR BR9106879A patent/BR9106879A/pt not_active Application Discontinuation
- 1991-09-23 AT AT91917033T patent/ATE194657T1/de not_active IP Right Cessation
- 1991-09-23 EP EP19990106514 patent/EP0953648A3/en not_active Withdrawn
- 1991-09-23 EP EP19910917033 patent/EP0550553B1/en not_active Expired - Lifetime
- 1991-09-23 KR KR1019930700913A patent/KR100372934B1/ko active
- 1991-09-23 WO PCT/GB1991/001632 patent/WO1992005263A1/en active IP Right Grant
- 1991-09-23 JP JP51739991A patent/JP3895366B2/ja not_active Expired - Fee Related
- 1991-09-23 CA CA 2091678 patent/CA2091678C/en not_active Expired - Lifetime
-
1992
- 1992-06-29 MX MX9203717A patent/MX9203717A/es unknown
-
1993
- 1993-03-23 NO NO19931057A patent/NO314550B1/no not_active IP Right Cessation
- 1993-03-23 GB GB9306044A patent/GB2263480B/en not_active Expired - Fee Related
- 1993-03-24 FI FI931309A patent/FI110438B/fi active
- 1993-03-25 OA OA60354A patent/OA09777A/en unknown
-
1995
- 1995-06-05 US US08/462,632 patent/US6541009B1/en not_active Expired - Fee Related
-
1998
- 1998-01-27 HK HK98100722A patent/HK1001656A1/xx not_active IP Right Cessation
-
2000
- 2000-09-26 GR GR20000402173T patent/GR3034484T3/el not_active IP Right Cessation
Also Published As
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| AU8648991A (en) | 1992-04-15 |
| JP3895366B2 (ja) | 2007-03-22 |
| GB9306044D0 (en) | 1993-06-02 |
| WO1992005263A1 (en) | 1992-04-02 |
| AU658836B2 (en) | 1995-05-04 |
| FI931309A0 (fi) | 1993-03-24 |
| DK0550553T3 (da) | 2000-10-23 |
| OA09777A (en) | 1993-11-30 |
| EP0953648A2 (en) | 1999-11-03 |
| EP0550553B1 (en) | 2000-07-12 |
| EP0550553A1 (en) | 1993-07-14 |
| ES2150416T3 (es) | 2000-12-01 |
| EP0953648A3 (en) | 2007-09-12 |
| FI931309A (fi) | 1993-03-24 |
| US6541009B1 (en) | 2003-04-01 |
| DE69132311T2 (de) | 2000-12-14 |
| NO931057L (no) | 1993-05-03 |
| MX9203717A (es) | 1992-09-01 |
| KR100372934B1 (ko) | 2003-12-24 |
| GB2263480A (en) | 1993-07-28 |
| HK1001656A1 (en) | 1998-07-03 |
| FI110438B (fi) | 2003-01-31 |
| JPH06504194A (ja) | 1994-05-19 |
| GR3034484T3 (en) | 2000-12-29 |
| NO931057D0 (no) | 1993-03-23 |
| CA2091678A1 (en) | 1992-03-26 |
| DE69132311D1 (de) | 2000-08-17 |
| CA2091678C (en) | 2003-04-22 |
| BR9106879A (pt) | 1993-07-20 |
| ATE194657T1 (de) | 2000-07-15 |
| GB2263480B (en) | 1994-07-20 |
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