NO311618B1 - Substituerte aralkyltioalkyltiopyridin til bekjempelse av Helicobacter-bakterier - Google Patents
Substituerte aralkyltioalkyltiopyridin til bekjempelse av Helicobacter-bakterier Download PDFInfo
- Publication number
- NO311618B1 NO311618B1 NO19965162A NO965162A NO311618B1 NO 311618 B1 NO311618 B1 NO 311618B1 NO 19965162 A NO19965162 A NO 19965162A NO 965162 A NO965162 A NO 965162A NO 311618 B1 NO311618 B1 NO 311618B1
- Authority
- NO
- Norway
- Prior art keywords
- hydrogen
- alkyl
- methyl
- compounds
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Other Air-Conditioning Systems (AREA)
- Mounting Of Printed Circuit Boards And The Like (AREA)
- Air Filters, Heat-Exchange Apparatuses, And Housings Of Air-Conditioning Units (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH184594 | 1994-06-10 | ||
| PCT/EP1995/002237 WO1995034554A1 (de) | 1994-06-10 | 1995-06-09 | Substituierte arylalkylthioalkylthiopyridine zur bekämpfung von helicobacter-bakterien |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO965162D0 NO965162D0 (no) | 1996-12-03 |
| NO965162L NO965162L (no) | 1997-02-05 |
| NO311618B1 true NO311618B1 (no) | 2001-12-17 |
Family
ID=4219963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19965162A NO311618B1 (no) | 1994-06-10 | 1996-12-03 | Substituerte aralkyltioalkyltiopyridin til bekjempelse av Helicobacter-bakterier |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5859030A (cs) |
| EP (1) | EP0764161A1 (cs) |
| JP (1) | JPH10501254A (cs) |
| CN (1) | CN1070488C (cs) |
| AU (1) | AU697572B2 (cs) |
| BG (1) | BG63502B1 (cs) |
| CA (1) | CA2192202A1 (cs) |
| CZ (1) | CZ288079B6 (cs) |
| EE (1) | EE03312B1 (cs) |
| FI (1) | FI964909L (cs) |
| HU (1) | HU220062B (cs) |
| MX (1) | MX9606300A (cs) |
| NO (1) | NO311618B1 (cs) |
| NZ (1) | NZ288609A (cs) |
| PL (1) | PL181801B1 (cs) |
| RO (1) | RO117792B1 (cs) |
| RU (1) | RU2139286C1 (cs) |
| SK (1) | SK281465B6 (cs) |
| WO (1) | WO1995034554A1 (cs) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997019593A1 (en) * | 1995-11-28 | 1997-06-05 | Wider Michael D | Antimicrobial composition and methods of use therefor |
| WO1999061438A1 (en) * | 1998-05-23 | 1999-12-02 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Quinoline-aminomethyl-pyridyl derivatives with anti-helicobacter activity |
| EP1154771A4 (en) * | 1999-02-26 | 2005-04-20 | Nitromed Inc | INHIBITORS OF THE PROTON NITROSIS AND NITROSYL PUMP, COMPOSITIONS AND METHODS OF USE |
| US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
| US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
| US6316020B1 (en) | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
| US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
| US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
| DK1556371T3 (da) * | 2002-07-19 | 2006-08-21 | Winston Pharmaceuticals Llc | Benzimidazol-derivater og deres anvendelse som prodrugs for protonpumpe-inhibitorer |
| WO2008036201A1 (en) * | 2006-09-19 | 2008-03-27 | Alevium Pharmaceuticals, Inc. | Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety |
| RU2449805C1 (ru) | 2011-01-27 | 2012-05-10 | Общество С Ограниченной Ответственностью "Гармония" | Пептидная фармацевтическая композиция, средство на ее основе для лечения гастродуоденальных заболеваний, вызываемых helicobacter pylori, и способ его использования |
| CN110294751B (zh) * | 2018-03-21 | 2020-11-20 | 湖南化工研究院有限公司 | 具生物活性的咪唑[4,5-b]并吡啶类化合物及其制备方法和应用 |
| CN110156752B (zh) * | 2019-05-28 | 2021-03-19 | 沈阳药科大学 | 2-[(吡啶-2-基甲基)硫基]-1h-苯并咪唑类化合物及应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1234058A (cs) * | 1968-10-21 | 1971-06-03 | ||
| SE418966B (sv) * | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
| JPS604826B2 (ja) * | 1978-09-12 | 1985-02-06 | 藤沢薬品工業株式会社 | インダゾ−ル酢酸類の製造法 |
| US4387225A (en) * | 1981-01-15 | 1983-06-07 | William H. Rorer, Inc. | Heterocyclic alkylene triazinones |
| JPS57200386A (en) * | 1981-06-04 | 1982-12-08 | Yoshitomi Pharmaceut Ind Ltd | Novel 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its salts |
| HU191757B (en) * | 1983-05-03 | 1987-04-28 | Byk Gulden Lomberg Chem Fab | Process for producing new tricyclic ethers |
| JP2563619B2 (ja) * | 1989-11-28 | 1996-12-11 | 株式会社東芝 | ダクト用換気扇 |
| US5504082A (en) * | 1992-06-01 | 1996-04-02 | Yoshitomi Pharmaceutical Industries, Ltd. | Pyridine compound and pharmaceutical compostions |
| CA2136993A1 (en) * | 1992-06-01 | 1993-12-09 | Takeshi Kawakita | Pyridine compound and pharmaceutical use thereof |
| DK0683776T3 (da) * | 1993-02-17 | 1999-10-18 | Byk Gulden Lomberg Chem Fab | Substituerede heteroarylalkylthiopyridiner til bekæmpelse af Helicobacter-bakterier |
| RU2154062C2 (ru) * | 1993-06-29 | 2000-08-10 | Бик Гульден Ломберг Хемише Фабрик Гмбх. | Замещенные арилтиоалкилтиопиридины, способ их получения, лекарственное средство на их основе и способ получения лекарственного средства. |
| PT731801E (pt) * | 1993-12-01 | 2002-04-29 | Byk Gulden Lomberg Chem Fab | Aminoalquilaminopiridinas substituidas |
-
1995
- 1995-06-09 CZ CZ19963624A patent/CZ288079B6/cs not_active IP Right Cessation
- 1995-06-09 PL PL95317613A patent/PL181801B1/pl unknown
- 1995-06-09 HU HU9603339A patent/HU220062B/hu not_active IP Right Cessation
- 1995-06-09 JP JP8501598A patent/JPH10501254A/ja not_active Withdrawn
- 1995-06-09 CA CA002192202A patent/CA2192202A1/en not_active Abandoned
- 1995-06-09 FI FI964909A patent/FI964909L/fi unknown
- 1995-06-09 AU AU27901/95A patent/AU697572B2/en not_active Ceased
- 1995-06-09 US US08/750,785 patent/US5859030A/en not_active Expired - Fee Related
- 1995-06-09 EE EE9600189A patent/EE03312B1/xx not_active IP Right Cessation
- 1995-06-09 RO RO96-02255A patent/RO117792B1/ro unknown
- 1995-06-09 EP EP95923288A patent/EP0764161A1/de not_active Withdrawn
- 1995-06-09 CN CN95194562A patent/CN1070488C/zh not_active Expired - Fee Related
- 1995-06-09 SK SK1576-96A patent/SK281465B6/sk unknown
- 1995-06-09 WO PCT/EP1995/002237 patent/WO1995034554A1/de not_active Ceased
- 1995-06-09 RU RU97100641/04A patent/RU2139286C1/ru not_active IP Right Cessation
- 1995-06-09 NZ NZ288609A patent/NZ288609A/xx unknown
-
1996
- 1996-11-21 BG BG101002A patent/BG63502B1/bg unknown
- 1996-12-03 NO NO19965162A patent/NO311618B1/no unknown
- 1996-12-10 MX MX9606300A patent/MX9606300A/es not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HUT75516A (en) | 1997-05-28 |
| CA2192202A1 (en) | 1995-12-21 |
| WO1995034554A1 (de) | 1995-12-21 |
| CZ362496A3 (en) | 1997-08-13 |
| PL317613A1 (en) | 1997-04-14 |
| BG63502B1 (bg) | 2002-03-29 |
| FI964909A7 (fi) | 1996-12-09 |
| EE03312B1 (et) | 2000-12-15 |
| NO965162L (no) | 1997-02-05 |
| NO965162D0 (no) | 1996-12-03 |
| HU220062B (hu) | 2001-10-28 |
| NZ288609A (en) | 1998-12-23 |
| CZ288079B6 (cs) | 2001-04-11 |
| JPH10501254A (ja) | 1998-02-03 |
| CN1070488C (zh) | 2001-09-05 |
| EP0764161A1 (de) | 1997-03-26 |
| FI964909A0 (fi) | 1996-12-09 |
| US5859030A (en) | 1999-01-12 |
| RU2139286C1 (ru) | 1999-10-10 |
| FI964909L (fi) | 1996-12-09 |
| CN1159803A (zh) | 1997-09-17 |
| HU9603339D0 (en) | 1997-01-28 |
| AU2790195A (en) | 1996-01-05 |
| SK281465B6 (sk) | 2001-04-09 |
| PL181801B1 (pl) | 2001-09-28 |
| HK1001957A1 (en) | 1998-07-24 |
| SK157696A3 (en) | 1997-06-04 |
| MX9606300A (es) | 1998-06-30 |
| BG101002A (bg) | 1997-08-29 |
| RO117792B1 (ro) | 2002-07-30 |
| AU697572B2 (en) | 1998-10-08 |
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| FI110778B (fi) | Menetelmä terapeuttisesti käyttökelpoisten substituoitujen aryylitioalkyylitiopyridiinien valmistamiseksi | |
| EP0683776B1 (de) | Substituierte heteroarylalkylthiopyridine zur bekämpfung von helicobacter bakterien | |
| US5922720A (en) | Piperazinothiopyridines for the control of Helicobacter bacteria |