NO308658B1 - Sammenføyde isoquinoliner som dopamin-reseptor-ligander - Google Patents

Sammenføyde isoquinoliner som dopamin-reseptor-ligander

Info

Publication number
NO308658B1
NO308658B1 NO980688A NO980688A NO308658B1 NO 308658 B1 NO308658 B1 NO 308658B1 NO 980688 A NO980688 A NO 980688A NO 980688 A NO980688 A NO 980688A NO 308658 B1 NO308658 B1 NO 308658B1
Authority
NO
Norway
Prior art keywords
receptor ligands
isoquinolines
joined
dopamine receptor
compounds
Prior art date
Application number
NO980688A
Other languages
English (en)
Norwegian (no)
Other versions
NO980688L (no
NO980688D0 (no
Inventor
David E Nichols
Richard Mailman
Debasis Ghosh
Original Assignee
Purdue Research Foundation
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation, Univ North Carolina filed Critical Purdue Research Foundation
Publication of NO980688L publication Critical patent/NO980688L/no
Publication of NO980688D0 publication Critical patent/NO980688D0/no
Publication of NO308658B1 publication Critical patent/NO308658B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
NO980688A 1995-08-18 1998-02-18 Sammenføyde isoquinoliner som dopamin-reseptor-ligander NO308658B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US251995P 1995-08-18 1995-08-18
PCT/US1996/013416 WO1997006799A1 (en) 1995-08-18 1996-08-16 Novel fused isoquinolines as dopamine receptor ligands

Publications (3)

Publication Number Publication Date
NO980688L NO980688L (no) 1998-02-18
NO980688D0 NO980688D0 (no) 1998-02-18
NO308658B1 true NO308658B1 (no) 2000-10-09

Family

ID=21701148

Family Applications (1)

Application Number Title Priority Date Filing Date
NO980688A NO308658B1 (no) 1995-08-18 1998-02-18 Sammenføyde isoquinoliner som dopamin-reseptor-ligander

Country Status (18)

Country Link
US (2) US5959110A (zh)
EP (1) EP0845988B1 (zh)
JP (1) JP2000505046A (zh)
CN (1) CN1199338A (zh)
AT (1) ATE209915T1 (zh)
AU (1) AU700688B2 (zh)
BR (1) BR9610323A (zh)
CA (1) CA2227585A1 (zh)
DE (1) DE69617700T2 (zh)
DK (1) DK0845988T3 (zh)
ES (1) ES2169257T3 (zh)
IL (1) IL122974A (zh)
MX (1) MX9801179A (zh)
NO (1) NO308658B1 (zh)
NZ (1) NZ316312A (zh)
PT (1) PT845988E (zh)
RU (1) RU2177001C2 (zh)
WO (1) WO1997006799A1 (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL122974A (en) * 1995-08-18 2000-11-21 Purdue Research Foundation Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them
AU8824201A (en) * 2000-08-11 2002-02-25 Bristol Myers Squibb Co Process for the preparation of dinapsoline
MXPA03006265A (es) * 2001-01-16 2004-06-25 Purdue Research Foundation Metodo de tratamiento de disfuncion relacionada con dopamina mediante administracion de un agonista de receptor de dopamina d1 completo, sin generacion de tolerancia.
US7091212B2 (en) 2001-08-10 2006-08-15 Purdue Research Foundation Chiral dinapsoline
DE60323339D1 (de) * 2002-02-15 2008-10-16 Darpharma Inc Monoester und asymmetrisch substituierte diester prodrugs der dopamin-d1-rezeptor-agonisten
JP2004190007A (ja) * 2002-11-27 2004-07-08 Konica Minolta Holdings Inc 色素およびインクジェット記録液
WO2005029077A1 (en) * 2003-09-24 2005-03-31 Biacore Ab Method and system for molecular interaction analysis
EP2010541A2 (en) * 2006-02-21 2009-01-07 Purdue Research Foundation Trans-fused chromenoisoquinolines, synthesis and methods for use
PL2317852T3 (pl) * 2008-07-16 2015-05-29 Richter Gedeon Nyrt Preparaty farmaceutyczne zawierające ligandy receptora dopaminy
EP2421862B1 (en) 2009-04-21 2014-06-11 Purdue Research Foundation Octahydrobenzoisoquinoline modulators of dopamine receptors and uses therefor
CN110068645B (zh) * 2019-04-03 2021-09-03 上海药明奥测医疗科技有限公司 液质联用检测尿液中环磷酸腺苷的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4346090A (en) * 1977-07-21 1982-08-24 Ayerst, Mckenna & Harrison Ltd. 13-Chloro-benzocycloheptapyridoisoquinolines and use as neuroleptics
US5047536A (en) * 1989-03-17 1991-09-10 Purdue Research Foundation Hexahydrobenzo(A)phenanthridine compounds
IE912999A1 (en) * 1990-09-07 1992-03-11 Abbott Lab Phenanthridine compounds
DE69334206D1 (de) * 1992-05-26 2008-04-03 Purdue Research Foundation Substituierte hexahydrobenzo(a) phenanthridine
IL122974A (en) * 1995-08-18 2000-11-21 Purdue Research Foundation Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US6194423B1 (en) 2001-02-27
NO980688L (no) 1998-02-18
RU2177001C2 (ru) 2001-12-20
BR9610323A (pt) 1999-12-21
DE69617700T2 (de) 2002-07-18
IL122974A (en) 2000-11-21
ES2169257T3 (es) 2002-07-01
AU6851396A (en) 1997-03-12
NO980688D0 (no) 1998-02-18
EP0845988B1 (en) 2001-12-05
JP2000505046A (ja) 2000-04-25
EP0845988A1 (en) 1998-06-10
CN1199338A (zh) 1998-11-18
AU700688B2 (en) 1999-01-14
PT845988E (pt) 2002-05-31
ATE209915T1 (de) 2001-12-15
WO1997006799A1 (en) 1997-02-27
IL122974A0 (en) 1998-08-16
DK0845988T3 (da) 2002-04-02
MX9801179A (es) 1998-04-30
EP0845988A4 (en) 1998-11-11
DE69617700D1 (de) 2002-01-17
CA2227585A1 (en) 1997-02-27
NZ316312A (en) 1999-06-29
US5959110A (en) 1999-09-28

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