EA199901049A2 - Спироимидазолиновые соединения, способ их получения и фармацевтическая композиция, содержащая их - Google Patents

Спироимидазолиновые соединения, способ их получения и фармацевтическая композиция, содержащая их

Info

Publication number
EA199901049A2
EA199901049A2 EA199901049A EA199901049A EA199901049A2 EA 199901049 A2 EA199901049 A2 EA 199901049A2 EA 199901049 A EA199901049 A EA 199901049A EA 199901049 A EA199901049 A EA 199901049A EA 199901049 A2 EA199901049 A2 EA 199901049A2
Authority
EA
Eurasian Patent Office
Prior art keywords
preparation
spiro
pharmaceutical composition
composition containing
imidazoline compounds
Prior art date
Application number
EA199901049A
Other languages
English (en)
Other versions
EA199901049A3 (ru
EA002979B1 (ru
Inventor
Алекс Корди
Марк Миллан
Адриан Ньюмен-Танкреди
Морисетт Брокко
Original Assignee
Адир Э Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Адир Э Компани filed Critical Адир Э Компани
Publication of EA199901049A3 publication Critical patent/EA199901049A3/ru
Publication of EA199901049A2 publication Critical patent/EA199901049A2/ru
Publication of EA002979B1 publication Critical patent/EA002979B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

Изобретение относится к новым спироимидазолиновым соединениям формулы (I)в которой A представляет необязательно замещенное бензольное кольцо, B представляет имидазолиновое кольцо формулы (Ia) или (Ib)к способу их получения и лекарственным средствам.
EA199901049A 1998-12-18 1999-12-17 Спироимидазолиновые соединения, способ их получения и фармацевтическая композиция, содержащая их EA002979B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9816000A FR2787450B1 (fr) 1998-12-18 1998-12-18 Nouveaux derives spiroimidazoliniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number Publication Date
EA199901049A3 EA199901049A3 (ru) 2000-08-28
EA199901049A2 true EA199901049A2 (ru) 2000-08-28
EA002979B1 EA002979B1 (ru) 2002-12-26

Family

ID=9534134

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199901049A EA002979B1 (ru) 1998-12-18 1999-12-17 Спироимидазолиновые соединения, способ их получения и фармацевтическая композиция, содержащая их

Country Status (22)

Country Link
US (1) US6172097B1 (ru)
EP (1) EP1010694B1 (ru)
JP (1) JP3457241B2 (ru)
KR (1) KR100472522B1 (ru)
CN (1) CN1149201C (ru)
AT (1) ATE246680T1 (ru)
AU (1) AU760373B2 (ru)
BR (1) BR9905904A (ru)
CA (1) CA2292920C (ru)
DE (1) DE69910156T2 (ru)
DK (1) DK1010694T3 (ru)
EA (1) EA002979B1 (ru)
ES (1) ES2205741T3 (ru)
FR (1) FR2787450B1 (ru)
HK (1) HK1029117A1 (ru)
HU (1) HU225820B1 (ru)
NO (1) NO314402B1 (ru)
NZ (1) NZ501890A (ru)
PL (1) PL202368B1 (ru)
PT (1) PT1010694E (ru)
SI (1) SI1010694T1 (ru)
ZA (1) ZA997735B (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6638981B2 (en) 2001-08-17 2003-10-28 Epicept Corporation Topical compositions and methods for treating pain
EP2254420A4 (en) 2008-02-20 2012-02-15 Targia Pharmaceuticals CNS PHARMACEUTICALS AND METHOD FOR THEIR USE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294185B1 (en) * 1993-03-12 2001-09-25 Auburn University Monomeric and polymeric cyclic amine and N-halamine compounds
FR2709306B1 (fr) * 1993-07-20 1995-10-20 Adir Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2707981B1 (fr) * 1993-07-20 1995-09-01 Adir Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2707982B1 (fr) * 1993-07-20 1995-09-01 Adir Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
DK1010694T3 (da) 2003-11-24
ATE246680T1 (de) 2003-08-15
NO996285L (no) 2000-06-19
FR2787450B1 (fr) 2001-01-26
KR20000067830A (ko) 2000-11-25
PT1010694E (pt) 2003-10-31
JP2000178257A (ja) 2000-06-27
CN1149201C (zh) 2004-05-12
ZA997735B (en) 2000-06-19
CN1264704A (zh) 2000-08-30
JP3457241B2 (ja) 2003-10-14
NO314402B1 (no) 2003-03-17
HU225820B1 (en) 2007-10-29
HK1029117A1 (en) 2001-03-23
NZ501890A (en) 2001-03-30
EA199901049A3 (ru) 2000-08-28
KR100472522B1 (ko) 2005-03-07
HUP9904629A2 (hu) 2000-08-28
HU9904629D0 (en) 2000-02-28
CA2292920A1 (fr) 2000-06-18
PL337265A1 (en) 2000-06-19
FR2787450A1 (fr) 2000-06-23
PL202368B1 (pl) 2009-06-30
NO996285D0 (no) 1999-12-17
DE69910156D1 (de) 2003-09-11
EP1010694A2 (fr) 2000-06-21
EP1010694A3 (fr) 2000-07-26
AU760373B2 (en) 2003-05-15
ES2205741T3 (es) 2004-05-01
HUP9904629A3 (en) 2000-12-28
BR9905904A (pt) 2000-08-29
EP1010694B1 (fr) 2003-08-06
US6172097B1 (en) 2001-01-09
EA002979B1 (ru) 2002-12-26
AU6529199A (en) 2000-06-22
CA2292920C (fr) 2004-01-27
SI1010694T1 (en) 2003-12-31
DE69910156T2 (de) 2004-06-09

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU