ZA997735B - Spiro imidazoline compounds, a process for their preparation and pharmaceutical compositions containing them. - Google Patents

Spiro imidazoline compounds, a process for their preparation and pharmaceutical compositions containing them.

Info

Publication number
ZA997735B
ZA997735B ZA9907735A ZA997735A ZA997735B ZA 997735 B ZA997735 B ZA 997735B ZA 9907735 A ZA9907735 A ZA 9907735A ZA 997735 A ZA997735 A ZA 997735A ZA 997735 B ZA997735 B ZA 997735B
Authority
ZA
South Africa
Prior art keywords
spiro
preparation
pharmaceutical compositions
compositions containing
imidazoline
Prior art date
Application number
ZA9907735A
Other languages
English (en)
Inventor
Alex Cordi
Mark Millan
Adrian Newman-Tancredi
Mauricette Brocco
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA997735B publication Critical patent/ZA997735B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
ZA9907735A 1998-12-18 1999-12-17 Spiro imidazoline compounds, a process for their preparation and pharmaceutical compositions containing them. ZA997735B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9816000A FR2787450B1 (fr) 1998-12-18 1998-12-18 Nouveaux derives spiroimidazoliniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA997735B true ZA997735B (en) 2000-06-19

Family

ID=9534134

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9907735A ZA997735B (en) 1998-12-18 1999-12-17 Spiro imidazoline compounds, a process for their preparation and pharmaceutical compositions containing them.

Country Status (22)

Country Link
US (1) US6172097B1 (xx)
EP (1) EP1010694B1 (xx)
JP (1) JP3457241B2 (xx)
KR (1) KR100472522B1 (xx)
CN (1) CN1149201C (xx)
AT (1) ATE246680T1 (xx)
AU (1) AU760373B2 (xx)
BR (1) BR9905904A (xx)
CA (1) CA2292920C (xx)
DE (1) DE69910156T2 (xx)
DK (1) DK1010694T3 (xx)
EA (1) EA002979B1 (xx)
ES (1) ES2205741T3 (xx)
FR (1) FR2787450B1 (xx)
HK (1) HK1029117A1 (xx)
HU (1) HU225820B1 (xx)
NO (1) NO314402B1 (xx)
NZ (1) NZ501890A (xx)
PL (1) PL202368B1 (xx)
PT (1) PT1010694E (xx)
SI (1) SI1010694T1 (xx)
ZA (1) ZA997735B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6638981B2 (en) 2001-08-17 2003-10-28 Epicept Corporation Topical compositions and methods for treating pain
CA2716080C (en) 2008-02-20 2016-12-13 Targia Pharmaceuticals Cns pharmaceutical compositions and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294185B1 (en) * 1993-03-12 2001-09-25 Auburn University Monomeric and polymeric cyclic amine and N-halamine compounds
FR2709306B1 (fr) * 1993-07-20 1995-10-20 Adir Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2707982B1 (fr) * 1993-07-20 1995-09-01 Adir Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2707981B1 (fr) * 1993-07-20 1995-09-01 Adir Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
CN1264704A (zh) 2000-08-30
FR2787450A1 (fr) 2000-06-23
PL337265A1 (en) 2000-06-19
EP1010694B1 (fr) 2003-08-06
CN1149201C (zh) 2004-05-12
ATE246680T1 (de) 2003-08-15
DE69910156T2 (de) 2004-06-09
HUP9904629A2 (hu) 2000-08-28
FR2787450B1 (fr) 2001-01-26
EA002979B1 (ru) 2002-12-26
PT1010694E (pt) 2003-10-31
DK1010694T3 (da) 2003-11-24
JP3457241B2 (ja) 2003-10-14
NO314402B1 (no) 2003-03-17
US6172097B1 (en) 2001-01-09
NO996285L (no) 2000-06-19
AU6529199A (en) 2000-06-22
SI1010694T1 (en) 2003-12-31
EA199901049A3 (ru) 2000-08-28
EP1010694A2 (fr) 2000-06-21
BR9905904A (pt) 2000-08-29
EP1010694A3 (fr) 2000-07-26
HK1029117A1 (en) 2001-03-23
NZ501890A (en) 2001-03-30
PL202368B1 (pl) 2009-06-30
JP2000178257A (ja) 2000-06-27
CA2292920A1 (fr) 2000-06-18
KR20000067830A (ko) 2000-11-25
DE69910156D1 (de) 2003-09-11
ES2205741T3 (es) 2004-05-01
CA2292920C (fr) 2004-01-27
HU9904629D0 (en) 2000-02-28
AU760373B2 (en) 2003-05-15
KR100472522B1 (ko) 2005-03-07
HUP9904629A3 (en) 2000-12-28
HU225820B1 (en) 2007-10-29
EA199901049A2 (ru) 2000-08-28
NO996285D0 (no) 1999-12-17

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