IL122974A - Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them - Google Patents
Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing themInfo
- Publication number
- IL122974A IL122974A IL12297496A IL12297496A IL122974A IL 122974 A IL122974 A IL 122974A IL 12297496 A IL12297496 A IL 12297496A IL 12297496 A IL12297496 A IL 12297496A IL 122974 A IL122974 A IL 122974A
- Authority
- IL
- Israel
- Prior art keywords
- naph
- isoquinoline
- optionally substituted
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US251995P | 1995-08-18 | 1995-08-18 | |
| PCT/US1996/013416 WO1997006799A1 (en) | 1995-08-18 | 1996-08-16 | Novel fused isoquinolines as dopamine receptor ligands |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL122974A0 IL122974A0 (en) | 1998-08-16 |
| IL122974A true IL122974A (en) | 2000-11-21 |
Family
ID=21701148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12297496A IL122974A (en) | 1995-08-18 | 1996-08-16 | Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US5959110A (zh) |
| EP (1) | EP0845988B1 (zh) |
| JP (1) | JP2000505046A (zh) |
| CN (1) | CN1199338A (zh) |
| AT (1) | ATE209915T1 (zh) |
| AU (1) | AU700688B2 (zh) |
| BR (1) | BR9610323A (zh) |
| CA (1) | CA2227585A1 (zh) |
| DE (1) | DE69617700T2 (zh) |
| DK (1) | DK0845988T3 (zh) |
| ES (1) | ES2169257T3 (zh) |
| IL (1) | IL122974A (zh) |
| MX (1) | MX9801179A (zh) |
| NO (1) | NO308658B1 (zh) |
| NZ (1) | NZ316312A (zh) |
| PT (1) | PT845988E (zh) |
| RU (1) | RU2177001C2 (zh) |
| WO (1) | WO1997006799A1 (zh) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL122974A (en) * | 1995-08-18 | 2000-11-21 | Purdue Research Foundation | Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them |
| AU8824201A (en) * | 2000-08-11 | 2002-02-25 | Bristol Myers Squibb Co | Process for the preparation of dinapsoline |
| MXPA03006265A (es) * | 2001-01-16 | 2004-06-25 | Purdue Research Foundation | Metodo de tratamiento de disfuncion relacionada con dopamina mediante administracion de un agonista de receptor de dopamina d1 completo, sin generacion de tolerancia. |
| US7091212B2 (en) | 2001-08-10 | 2006-08-15 | Purdue Research Foundation | Chiral dinapsoline |
| DE60323339D1 (de) * | 2002-02-15 | 2008-10-16 | Darpharma Inc | Monoester und asymmetrisch substituierte diester prodrugs der dopamin-d1-rezeptor-agonisten |
| JP2004190007A (ja) * | 2002-11-27 | 2004-07-08 | Konica Minolta Holdings Inc | 色素およびインクジェット記録液 |
| WO2005029077A1 (en) * | 2003-09-24 | 2005-03-31 | Biacore Ab | Method and system for molecular interaction analysis |
| EP2010541A2 (en) * | 2006-02-21 | 2009-01-07 | Purdue Research Foundation | Trans-fused chromenoisoquinolines, synthesis and methods for use |
| PL2317852T3 (pl) * | 2008-07-16 | 2015-05-29 | Richter Gedeon Nyrt | Preparaty farmaceutyczne zawierające ligandy receptora dopaminy |
| EP2421862B1 (en) | 2009-04-21 | 2014-06-11 | Purdue Research Foundation | Octahydrobenzoisoquinoline modulators of dopamine receptors and uses therefor |
| CN110068645B (zh) * | 2019-04-03 | 2021-09-03 | 上海药明奥测医疗科技有限公司 | 液质联用检测尿液中环磷酸腺苷的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4346090A (en) * | 1977-07-21 | 1982-08-24 | Ayerst, Mckenna & Harrison Ltd. | 13-Chloro-benzocycloheptapyridoisoquinolines and use as neuroleptics |
| US5047536A (en) * | 1989-03-17 | 1991-09-10 | Purdue Research Foundation | Hexahydrobenzo(A)phenanthridine compounds |
| IE912999A1 (en) * | 1990-09-07 | 1992-03-11 | Abbott Lab | Phenanthridine compounds |
| DE69334206D1 (de) * | 1992-05-26 | 2008-04-03 | Purdue Research Foundation | Substituierte hexahydrobenzo(a) phenanthridine |
| IL122974A (en) * | 1995-08-18 | 2000-11-21 | Purdue Research Foundation | Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them |
-
1996
- 1996-08-16 IL IL12297496A patent/IL122974A/xx not_active IP Right Cessation
- 1996-08-16 MX MX9801179A patent/MX9801179A/es not_active IP Right Cessation
- 1996-08-16 AT AT96928941T patent/ATE209915T1/de not_active IP Right Cessation
- 1996-08-16 US US08/727,451 patent/US5959110A/en not_active Expired - Lifetime
- 1996-08-16 JP JP9509550A patent/JP2000505046A/ja not_active Ceased
- 1996-08-16 DK DK96928941T patent/DK0845988T3/da active
- 1996-08-16 BR BR9610323-0A patent/BR9610323A/pt not_active IP Right Cessation
- 1996-08-16 RU RU98104276/14A patent/RU2177001C2/ru active
- 1996-08-16 DE DE69617700T patent/DE69617700T2/de not_active Expired - Fee Related
- 1996-08-16 ES ES96928941T patent/ES2169257T3/es not_active Expired - Lifetime
- 1996-08-16 CN CN96197477A patent/CN1199338A/zh active Pending
- 1996-08-16 NZ NZ316312A patent/NZ316312A/xx not_active IP Right Cessation
- 1996-08-16 AU AU68513/96A patent/AU700688B2/en not_active Ceased
- 1996-08-16 PT PT96928941T patent/PT845988E/pt unknown
- 1996-08-16 CA CA002227585A patent/CA2227585A1/en not_active Abandoned
- 1996-08-16 EP EP96928941A patent/EP0845988B1/en not_active Expired - Lifetime
- 1996-08-16 WO PCT/US1996/013416 patent/WO1997006799A1/en active IP Right Grant
-
1998
- 1998-02-18 NO NO980688A patent/NO308658B1/no unknown
-
1999
- 1999-08-13 US US09/374,423 patent/US6194423B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6194423B1 (en) | 2001-02-27 |
| NO980688L (no) | 1998-02-18 |
| RU2177001C2 (ru) | 2001-12-20 |
| BR9610323A (pt) | 1999-12-21 |
| NO308658B1 (no) | 2000-10-09 |
| DE69617700T2 (de) | 2002-07-18 |
| ES2169257T3 (es) | 2002-07-01 |
| AU6851396A (en) | 1997-03-12 |
| NO980688D0 (no) | 1998-02-18 |
| EP0845988B1 (en) | 2001-12-05 |
| JP2000505046A (ja) | 2000-04-25 |
| EP0845988A1 (en) | 1998-06-10 |
| CN1199338A (zh) | 1998-11-18 |
| AU700688B2 (en) | 1999-01-14 |
| PT845988E (pt) | 2002-05-31 |
| ATE209915T1 (de) | 2001-12-15 |
| WO1997006799A1 (en) | 1997-02-27 |
| IL122974A0 (en) | 1998-08-16 |
| DK0845988T3 (da) | 2002-04-02 |
| MX9801179A (es) | 1998-04-30 |
| EP0845988A4 (en) | 1998-11-11 |
| DE69617700D1 (de) | 2002-01-17 |
| CA2227585A1 (en) | 1997-02-27 |
| NZ316312A (en) | 1999-06-29 |
| US5959110A (en) | 1999-09-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |