NO308413B1 - Antigen blanding, DNA-segment som koder for et antigen, rekombinant vektor og vertscelle som innbefatter DNA-segmentet samt anvendelser av et antigen - Google Patents
Antigen blanding, DNA-segment som koder for et antigen, rekombinant vektor og vertscelle som innbefatter DNA-segmentet samt anvendelser av et antigenInfo
- Publication number
- NO308413B1 NO308413B1 NO940502A NO940502A NO308413B1 NO 308413 B1 NO308413 B1 NO 308413B1 NO 940502 A NO940502 A NO 940502A NO 940502 A NO940502 A NO 940502A NO 308413 B1 NO308413 B1 NO 308413B1
- Authority
- NO
- Norway
- Prior art keywords
- antigen
- dna segment
- omps
- proteins
- host cell
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 4
- 102000036639 antigens Human genes 0.000 title abstract 4
- 108091007433 antigens Proteins 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 241000588655 Moraxella catarrhalis Species 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 1
- 108010052285 Membrane Proteins Proteins 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
- C07K14/212—Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/745,591 US5552146A (en) | 1991-08-15 | 1991-08-15 | Methods and compositions relating to useful antigens of Moraxella catarrhalis |
PCT/US1992/006869 WO1993003761A1 (en) | 1991-08-15 | 1992-08-14 | METHODS AND COMPOSITIONS RELATING TO USEFUL ANTIGENS OF $i(MORAXELLA CATARRHALIS) |
Publications (3)
Publication Number | Publication Date |
---|---|
NO940502D0 NO940502D0 (no) | 1994-02-14 |
NO940502L NO940502L (no) | 1994-03-28 |
NO308413B1 true NO308413B1 (no) | 2000-09-11 |
Family
ID=24997358
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO940502A NO308413B1 (no) | 1991-08-15 | 1994-02-14 | Antigen blanding, DNA-segment som koder for et antigen, rekombinant vektor og vertscelle som innbefatter DNA-segmentet samt anvendelser av et antigen |
NO20002413A NO20002413L (no) | 1991-08-15 | 2000-05-09 | Antistoffer mot Moraxella proteiner og anvendelse derav, samt sett for pÕvisning av antigen og farmasøytisk preparat som inneholder antistoffer |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20002413A NO20002413L (no) | 1991-08-15 | 2000-05-09 | Antistoffer mot Moraxella proteiner og anvendelse derav, samt sett for pÕvisning av antigen og farmasøytisk preparat som inneholder antistoffer |
Country Status (14)
Country | Link |
---|---|
US (3) | US5552146A (ja) |
EP (1) | EP0612250B1 (ja) |
JP (1) | JP3499868B2 (ja) |
KR (1) | KR100271888B1 (ja) |
AT (1) | ATE140627T1 (ja) |
AU (1) | AU666329B2 (ja) |
CA (1) | CA2115565C (ja) |
DE (1) | DE69212495T2 (ja) |
DK (1) | DK0612250T3 (ja) |
ES (1) | ES2092696T3 (ja) |
FI (1) | FI106844B (ja) |
GR (1) | GR3021423T3 (ja) |
NO (2) | NO308413B1 (ja) |
WO (1) | WO1993003761A1 (ja) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2693654B1 (fr) * | 1992-07-20 | 1994-08-26 | Oreal | Médicament, notamment immunomodulateur, contenant des enveloppes ou fractions d'enveloppes de bactéries filamenteuses non photosynthétiques et non fructifiantes, et sa préparation. |
ATE190502T1 (de) * | 1993-05-13 | 2000-04-15 | American Cyanamid Co | Herstellung und verwendungen von los-verminderten aussenmembran-proteinen von gram-negativen kokken |
US5712118A (en) * | 1993-09-29 | 1998-01-27 | Research Foundation Of State University Of New York | Vaccine for branhamella catarrhalis |
US5607846A (en) * | 1994-05-17 | 1997-03-04 | Research Foundation Of State University Of New York | Vaccine for moraxella catarrhalis |
US6121427A (en) * | 1994-10-24 | 2000-09-19 | Connaught Laboratories Limited | Major outer membrane protein CD of branhamella |
US6335018B1 (en) * | 1995-05-01 | 2002-01-01 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
US6440425B1 (en) * | 1995-05-01 | 2002-08-27 | Aventis Pasteur Limited | High molecular weight major outer membrane protein of moraxella |
US6290970B1 (en) | 1995-10-11 | 2001-09-18 | Aventis Pasteur Limited | Transferrin receptor protein of Moraxella |
US7341727B1 (en) * | 1996-05-03 | 2008-03-11 | Emergent Product Development Gaithersburg Inc. | M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same |
KR100500000B1 (ko) * | 1996-05-03 | 2005-12-12 | 안텍스 바이오로직스 인코퍼레이션 | 모락셀라카타르할리스외측막단백질-16폴리펩티드,이의유전자서열및이의용도 |
US6004562A (en) * | 1996-08-16 | 1999-12-21 | The Research Foundation Of The State University Of New York | Outer membrane protein B1 of Moraxella catarrhalis |
US6558677B2 (en) * | 1996-10-15 | 2003-05-06 | Wendell D. Zollinger | Vaccine against gram negative bacteria |
BR9714160A (pt) | 1996-12-20 | 2000-05-02 | Univ Texas | Antìgenos uspa1 e uspa2 de moraxella catarrhalis |
GB9810084D0 (en) | 1998-05-11 | 1998-07-08 | Cortecs Uk Ltd | Proteins |
WO1999058682A2 (en) * | 1998-05-12 | 1999-11-18 | Smithkline Beecham Biologicals S.A. | Compounds from moraxella catarrhalis |
GB9810285D0 (en) * | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
GB9812440D0 (en) * | 1998-06-09 | 1998-08-05 | Smithkline Beecham Biolog | Novel compounds |
DE60038166T2 (de) | 1999-03-19 | 2009-03-12 | Glaxosmithkline Biologicals S.A., Rixensart | Impfstoff gegen bakterielle antigene |
GB9914945D0 (en) * | 1999-06-25 | 1999-08-25 | Smithkline Beecham Biolog | Novel compounds |
GB9921691D0 (en) * | 1999-09-14 | 1999-11-17 | Smithkline Beecham Sa | Novel compounds |
GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
GB0103171D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
EP2255826B1 (en) | 2002-08-02 | 2016-04-13 | GlaxoSmithKline Biologicals S.A. | Neisserial vaccine compositions comprising a combination of antigens |
GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
CN101180079B (zh) | 2005-04-08 | 2012-07-18 | 惠氏公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物 |
US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
NZ569168A (en) | 2005-12-22 | 2012-02-24 | Glaxosmithkline Biolog Sa | Streptococcus pneumoniae polysaccharide conjugate vaccine comprising 19F-DT conjugate |
ZA200805602B (en) | 2006-01-17 | 2009-12-30 | Arne Forsgren | A novel surface exposed haemophilus influenzae protein (protein E; pE) |
KR101579947B1 (ko) | 2007-06-26 | 2015-12-28 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 스트렙토코쿠스 뉴모니애 캡슐 다당류 컨쥬게이트를 포함하는 백신 |
JP5723768B2 (ja) | 2008-05-30 | 2015-05-27 | ザ ユナイテッド ステイツ オブ アメリカ, アズ レプレゼンテッド バイ ザ セクレタリー オブ ジ アーミー, オン ビハーフ オブ ウォルター リード アーミー インスティチュート オブ リサーチ | 髄膜炎菌性多価未変性外膜小胞ワクチン、その作製方法およびその使用 |
GB201003922D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Conjugation process |
GB201003924D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Immunogenic composition |
CN103002910A (zh) | 2010-03-10 | 2013-03-27 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗组合物 |
GB201103836D0 (en) | 2011-03-07 | 2011-04-20 | Glaxosmithkline Biolog Sa | Conjugation process |
GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
GB201621686D0 (en) | 2016-12-20 | 2017-02-01 | Glaxosmithkline Biologicals Sa | Novel methods for inducing an immune response |
IE87414B1 (en) | 2017-05-30 | 2023-07-19 | Glaxosmithkline Biologicals Sa | Novel methods for manufacturing an adjuvant |
BR112020010790A2 (pt) | 2017-12-01 | 2020-11-10 | Glaxosmithkline Biologicals S.A. | purificação da saponina |
MX2021001479A (es) | 2018-08-07 | 2021-04-28 | Glaxosmithkline Biologicals Sa | Novedosos procesos y vacunas. |
US20220339282A1 (en) | 2018-11-29 | 2022-10-27 | Glaxosmithkline Biologicals Sa | Methods for manufacturing an adjuvant |
JP2022535091A (ja) | 2019-06-05 | 2022-08-04 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | サポニン精製 |
GB202205833D0 (en) | 2022-04-21 | 2022-06-08 | Glaxosmithkline Biologicals Sa | Bacteriophage |
WO2024017827A1 (en) | 2022-07-19 | 2024-01-25 | Glaxosmithkline Biologicals Sa | Continuous process for vaccine production |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5030556A (en) * | 1989-03-30 | 1991-07-09 | Danielle Beaulieu | Species-specific DNNA probe for the detection of Branhamella catarrhalis |
-
1991
- 1991-08-15 US US07/745,591 patent/US5552146A/en not_active Expired - Lifetime
-
1992
- 1992-08-14 CA CA002115565A patent/CA2115565C/en not_active Expired - Fee Related
- 1992-08-14 DE DE69212495T patent/DE69212495T2/de not_active Expired - Fee Related
- 1992-08-14 DK DK92918273.1T patent/DK0612250T3/da active
- 1992-08-14 AU AU24878/92A patent/AU666329B2/en not_active Ceased
- 1992-08-14 KR KR1019940700431A patent/KR100271888B1/ko not_active IP Right Cessation
- 1992-08-14 AT AT92918273T patent/ATE140627T1/de not_active IP Right Cessation
- 1992-08-14 ES ES92918273T patent/ES2092696T3/es not_active Expired - Lifetime
- 1992-08-14 EP EP92918273A patent/EP0612250B1/en not_active Expired - Lifetime
- 1992-08-14 JP JP50448193A patent/JP3499868B2/ja not_active Expired - Fee Related
- 1992-08-14 WO PCT/US1992/006869 patent/WO1993003761A1/en active IP Right Grant
-
1994
- 1994-02-14 NO NO940502A patent/NO308413B1/no unknown
- 1994-02-14 FI FI940681A patent/FI106844B/fi active
- 1994-09-19 US US08/193,150 patent/US5759813A/en not_active Expired - Fee Related
-
1995
- 1995-05-25 US US08/450,002 patent/US5599693A/en not_active Expired - Lifetime
-
1996
- 1996-10-23 GR GR960402795T patent/GR3021423T3/el unknown
-
2000
- 2000-05-09 NO NO20002413A patent/NO20002413L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO940502L (no) | 1994-03-28 |
FI940681A0 (fi) | 1994-02-14 |
NO20002413D0 (no) | 2000-05-09 |
US5759813A (en) | 1998-06-02 |
DK0612250T3 (da) | 1996-11-25 |
CA2115565A1 (en) | 1993-03-04 |
NO20002413L (no) | 2000-05-09 |
EP0612250A1 (en) | 1994-08-31 |
JPH07501210A (ja) | 1995-02-09 |
KR100271888B1 (ko) | 2000-11-15 |
US5552146A (en) | 1996-09-03 |
FI940681A (fi) | 1994-04-07 |
ATE140627T1 (de) | 1996-08-15 |
DE69212495D1 (de) | 1996-08-29 |
FI106844B (fi) | 2001-04-30 |
DE69212495T2 (de) | 1997-03-06 |
EP0612250B1 (en) | 1996-07-24 |
NO940502D0 (no) | 1994-02-14 |
JP3499868B2 (ja) | 2004-02-23 |
ES2092696T3 (es) | 1996-12-01 |
WO1993003761A1 (en) | 1993-03-04 |
AU2487892A (en) | 1993-03-16 |
US5599693A (en) | 1997-02-04 |
AU666329B2 (en) | 1996-02-08 |
CA2115565C (en) | 2007-08-07 |
GR3021423T3 (en) | 1997-01-31 |
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