WO1996034884A3 - Synthetic peptides of m. gallisepticum, antibodies thereto, their preparation and use - Google Patents

Synthetic peptides of m. gallisepticum, antibodies thereto, their preparation and use Download PDF

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Publication number
WO1996034884A3
WO1996034884A3 PCT/SI1996/000011 SI9600011W WO9634884A3 WO 1996034884 A3 WO1996034884 A3 WO 1996034884A3 SI 9600011 W SI9600011 W SI 9600011W WO 9634884 A3 WO9634884 A3 WO 9634884A3
Authority
WO
WIPO (PCT)
Prior art keywords
gallisepticum
preparation
antibodies
mycoplasma
native
Prior art date
Application number
PCT/SI1996/000011
Other languages
French (fr)
Other versions
WO1996034884A2 (en
Inventor
Janko Kos
Dusan Bencina
Dusan Dovc
Franc Gubensek
Original Assignee
Inst Jozef Stefan
Janko Kos
Dusan Bencina
Dusan Dovc
Franc Gubensek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Jozef Stefan, Janko Kos, Dusan Bencina, Dusan Dovc, Franc Gubensek filed Critical Inst Jozef Stefan
Priority to AU54140/96A priority Critical patent/AU5414096A/en
Priority to GB9723289A priority patent/GB2314560B/en
Priority to DE19681356T priority patent/DE19681356T1/en
Publication of WO1996034884A2 publication Critical patent/WO1996034884A2/en
Publication of WO1996034884A3 publication Critical patent/WO1996034884A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/30—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention describes novel synthetic peptides imitating natural epitopes on the membrane of pathogenic mycoplasma M. gallisepticum and a process for the preparation thereof. By the mentioned peptides native antigens in serological tests can be substituted and they can be used as vaccines or as antigens for the preparation of antibodies. Antibodies prepared by means of these peptides recognize native mycoplasma epitopes and are useful in various diagnostic tests for determination of poultry infections with M. gallisepticum, they prevent the growth of the mentioned mycoplasma and are also suitable for the isolation of native or recombinant main immunogenic protein pMGA or its subunits.
PCT/SI1996/000011 1995-05-05 1996-04-29 Synthetic peptides of m. gallisepticum, antibodies thereto, their preparation and use WO1996034884A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU54140/96A AU5414096A (en) 1995-05-05 1996-04-29 Synthetic peptides of m. gallisepticum, antibodies thereto, their preparation and use
GB9723289A GB2314560B (en) 1995-05-05 1996-04-29 Synthetic peptides of m. gallisepticum, antibodies thereto, their preparations and use
DE19681356T DE19681356T1 (en) 1995-05-05 1996-04-29 New synthetic peptides and their antibodies, their production and use in diagnosis and therapy of M. gallisepticum

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SIP-9500155 1995-05-05
SI9500155A SI9500155A (en) 1995-05-05 1995-05-05 Novel synthetic peptides and their antibodies, their prepatation and use in diagnostics and therapy of m. gallisepticum

Publications (2)

Publication Number Publication Date
WO1996034884A2 WO1996034884A2 (en) 1996-11-07
WO1996034884A3 true WO1996034884A3 (en) 1996-12-05

Family

ID=20431616

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SI1996/000011 WO1996034884A2 (en) 1995-05-05 1996-04-29 Synthetic peptides of m. gallisepticum, antibodies thereto, their preparation and use

Country Status (5)

Country Link
AU (1) AU5414096A (en)
DE (1) DE19681356T1 (en)
GB (1) GB2314560B (en)
SI (1) SI9500155A (en)
WO (1) WO1996034884A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204003B1 (en) 1997-09-19 2001-03-20 Synbiotics Corporation Methods for the diagnosis of feline infectious anemia

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
C.M.FALCOMER E.A.: "Chain reversals in model peptides...", J.AM.CHEM.SOC., vol. 114, no. 11, 1992, pages 4036 - 4042, XP002014933 *
P.F.MARKHAM E.A.: "Molecular cloning of a member of the gene family that encodes pMGA, a hemagglutinin of M. gallisepticum", INFECTION AND IMMUNITY, vol. 61, no. 3, March 1993 (1993-03-01), WASHINGTON US, pages 903 - 909, XP002014934 *

Also Published As

Publication number Publication date
GB2314560A (en) 1998-01-07
GB2314560B (en) 1999-09-29
WO1996034884A2 (en) 1996-11-07
AU5414096A (en) 1996-11-21
SI9500155A (en) 1996-12-31
DE19681356T1 (en) 1998-08-20
GB2314560A8 (en) 1999-08-12
GB9723289D0 (en) 1998-01-07

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