NO308306B1 - 17-difluormethylen-østratriener - Google Patents

17-difluormethylen-østratriener

Info

Publication number
NO308306B1
NO308306B1 NO974206A NO974206A NO308306B1 NO 308306 B1 NO308306 B1 NO 308306B1 NO 974206 A NO974206 A NO 974206A NO 974206 A NO974206 A NO 974206A NO 308306 B1 NO308306 B1 NO 308306B1
Authority
NO
Norway
Prior art keywords
hydrogen atom
beta
alpha
estratrienes
difluoromethyl
Prior art date
Application number
NO974206A
Other languages
English (en)
Norwegian (no)
Other versions
NO974206D0 (no
NO974206L (no
Inventor
Rolf Bohlmann
Gabor Rubanyl
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO974206D0 publication Critical patent/NO974206D0/no
Publication of NO974206L publication Critical patent/NO974206L/no
Publication of NO308306B1 publication Critical patent/NO308306B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/02Halogenated hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Vehicle Body Suspensions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Ceramic Products (AREA)
  • Electrical Control Of Air Or Fuel Supplied To Internal-Combustion Engine (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Exhaust-Gas Circulating Devices (AREA)
  • Saccharide Compounds (AREA)
NO974206A 1995-03-13 1997-09-12 17-difluormethylen-østratriener NO308306B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19509729A DE19509729A1 (de) 1995-03-13 1995-03-13 17-Difluormethylen-Estratriene
PCT/EP1996/001069 WO1996028462A1 (de) 1995-03-13 1996-03-13 17-difluormethylen-estratriene

Publications (3)

Publication Number Publication Date
NO974206D0 NO974206D0 (no) 1997-09-12
NO974206L NO974206L (no) 1997-11-13
NO308306B1 true NO308306B1 (no) 2000-08-28

Family

ID=7756963

Family Applications (1)

Application Number Title Priority Date Filing Date
NO974206A NO308306B1 (no) 1995-03-13 1997-09-12 17-difluormethylen-østratriener

Country Status (21)

Country Link
US (2) US6018062A (cs)
EP (1) EP0815120B1 (cs)
JP (1) JPH11501644A (cs)
KR (1) KR19980703002A (cs)
AT (1) ATE199159T1 (cs)
AU (1) AU693335B2 (cs)
BR (1) BR9612787A (cs)
CA (1) CA2215201A1 (cs)
CZ (1) CZ281097A3 (cs)
DE (2) DE19509729A1 (cs)
HU (1) HUP9801846A3 (cs)
IL (1) IL117497A (cs)
IS (1) IS4556A (cs)
NO (1) NO308306B1 (cs)
PL (1) PL322199A1 (cs)
RU (1) RU2155770C2 (cs)
SI (1) SI9620030A (cs)
SK (1) SK121697A3 (cs)
TR (1) TR199700950T1 (cs)
WO (1) WO1996028462A1 (cs)
ZA (1) ZA962037B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU703814B2 (en) * 1995-12-04 1999-04-01 Wyeth Antioxidant
US5773432A (en) * 1996-10-30 1998-06-30 Schering Aktiengesellschaft Method for lowering plasma levels of lipoprotein(a)
EP1654325A1 (en) * 2003-08-11 2006-05-10 Industria Chimica Reggiana I.C.R. S.P.A. Chemical composition and method of polymerisation thereof for use on vehicle bodywork repair
US20080255076A1 (en) * 2004-06-29 2008-10-16 Jadolabs Gmbh Steroid-Derived Pharmaceutical Compositions
US8030298B2 (en) 2005-05-26 2011-10-04 Abbott Products Gmbh 17β-HSD1 and STS inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3741800A1 (de) * 1987-12-07 1989-06-15 Schering Ag 17-halogenmethylen-estratriene
US5783571A (en) * 1991-01-07 1998-07-21 Pherin Corporation Method of altering hypothalamic function by nasal administration of estrene steroids
US5883087A (en) * 1991-01-07 1999-03-16 Pherin Corporation Androstane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US5969168A (en) * 1991-01-07 1999-10-19 Pherin Corporation Androstanes for inducing hypothalamic effects
US5773432A (en) * 1996-10-30 1998-06-30 Schering Aktiengesellschaft Method for lowering plasma levels of lipoprotein(a)

Also Published As

Publication number Publication date
ZA962037B (en) 1996-09-25
DE59606435D1 (de) 2001-03-22
US6136800A (en) 2000-10-24
MX9707006A (es) 1997-11-29
IL117497A (en) 1999-12-22
SK121697A3 (en) 1998-02-04
BR9612787A (pt) 1999-11-23
HUP9801846A2 (hu) 1998-12-28
CA2215201A1 (en) 1996-09-19
WO1996028462A1 (de) 1996-09-19
JPH11501644A (ja) 1999-02-09
PL322199A1 (en) 1998-01-19
ATE199159T1 (de) 2001-02-15
AU5107896A (en) 1996-10-02
NO974206D0 (no) 1997-09-12
RU2155770C2 (ru) 2000-09-10
AU693335B2 (en) 1998-06-25
EP0815120B1 (de) 2001-02-14
NO974206L (no) 1997-11-13
US6018062A (en) 2000-01-25
TR199700950T1 (xx) 1998-02-21
IL117497A0 (en) 1996-07-23
CZ281097A3 (cs) 1998-02-18
DE19509729A1 (de) 1996-09-19
KR19980703002A (ko) 1998-09-05
SI9620030A (sl) 1998-02-28
IS4556A (is) 1997-09-08
HUP9801846A3 (en) 1999-03-01
EP0815120A1 (de) 1998-01-07

Similar Documents

Publication Publication Date Title
NL350077I1 (nl) Cyprosulfamide
HUP0001192A2 (hu) Topiramát és származékainak alkalmazása elhízás kezelésére használható gyógyszerkészítmények előállítására
TR199801255T2 (xx) Vitronektin resept�r antagonistleri.
AR001440A1 (es) Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen.
YU11997A (sh) Laktamski derivati i njihove farmaceutske kompozicije
ATE270817T1 (de) Fungizide
YU40997A (sh) Novi oksadiazoli, postupci za njihovo pripremanje
TR199701146T1 (xx) N�rotensin resept�rleri �zerinde etkili 1-Fenilpirazol-3-Karboksamidler.
MX9805181A (es) Derivados de lactona a partir de derivados de 17.beta- carboxi, carbotio y amida androstano.
TR200201102T2 (tr) Yeni oligosakkaritler, bunların hazırlanması ve bunları içeren ilaç bileşimleri
TR199701728T1 (xx) Sialil-Lewis X ve sialil-Lewis A taklitleri olarak digikosilatlanm�� 1,-2-dioller.
TR199701287T1 (xx) Azasikloalkan t�revleri, haz�rlan��lar� ve terapideki uygulamalar�.
DK0696278T3 (da) Herbicidtvirkende substituerede 1-phenyl- eller 1-pyridinylbenzotriazoler
ATE338576T1 (de) Kosmetische zusammensetzungen
DK0852580T3 (da) Fremgangsmåde til fremstilling af dihydroxypyrimidin-derivater
ATE177293T1 (de) Ausziehführungsgarnitur für schubladen
DE59606435D1 (de) 17-difluormethylen-estratriene
TW350041B (en) Bis-depside tertiary alkyl ester derivatives and chemical positive photoresist material
TR199701298T1 (xx) Tetralinler.
BG101221A (bg) N-заместени азабициклохептанови производни, приложими като невролептици
TR199700802T2 (xx) Triazin t�revleri.
AR009105A1 (es) Derivados de n-(benzotiazol-2-il) piperidina-1-etanamina, su preparacion y aplicacion en terapeutica
TR200003203T2 (tr) Karboksaldehitin saflaştırılması
DE59803066D1 (de) Substituierte benzyloxyimino-verbindungen
TW346483B (en) Benzene derivatives