NO307256B1 - Tiadiazoler, farmasoeytisk preparat inneholdende slike forbindelser og deres anvendelse - Google Patents

Tiadiazoler, farmasoeytisk preparat inneholdende slike forbindelser og deres anvendelse

Info

Publication number
NO307256B1
NO307256B1 NO964773A NO964773A NO307256B1 NO 307256 B1 NO307256 B1 NO 307256B1 NO 964773 A NO964773 A NO 964773A NO 964773 A NO964773 A NO 964773A NO 307256 B1 NO307256 B1 NO 307256B1
Authority
NO
Norway
Prior art keywords
alkyl
hydroxyalkyl
alkoxy
thiadiazolyl
compounds
Prior art date
Application number
NO964773A
Other languages
English (en)
Norwegian (no)
Other versions
NO964773L (no
NO964773D0 (no
Inventor
David J Aldous
Thomas R Bailey
Guy Dominic Diana
Theodore J Nitz
Original Assignee
Sanofi Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Winthrop Inc filed Critical Sanofi Winthrop Inc
Publication of NO964773L publication Critical patent/NO964773L/no
Publication of NO964773D0 publication Critical patent/NO964773D0/no
Publication of NO307256B1 publication Critical patent/NO307256B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
NO964773A 1994-05-13 1996-11-11 Tiadiazoler, farmasoeytisk preparat inneholdende slike forbindelser og deres anvendelse NO307256B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/242,529 US5453433A (en) 1994-05-13 1994-05-13 Thiadiazoles and antipicornaviral compositions
PCT/US1995/005790 WO1995031198A1 (en) 1994-05-13 1995-05-10 Thiadiazoles and their use as antipicornaviral agents

Publications (3)

Publication Number Publication Date
NO964773L NO964773L (no) 1996-11-11
NO964773D0 NO964773D0 (no) 1996-11-11
NO307256B1 true NO307256B1 (no) 2000-03-06

Family

ID=22915137

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964773A NO307256B1 (no) 1994-05-13 1996-11-11 Tiadiazoler, farmasoeytisk preparat inneholdende slike forbindelser og deres anvendelse

Country Status (15)

Country Link
US (5) US5453433A (ja)
EP (1) EP0759755B1 (ja)
JP (1) JP4158946B2 (ja)
KR (1) KR100383495B1 (ja)
CN (1) CN1095664C (ja)
AT (1) ATE247112T1 (ja)
AU (1) AU691923B2 (ja)
CA (1) CA2190130C (ja)
CZ (1) CZ289061B6 (ja)
DE (1) DE69531491D1 (ja)
NO (1) NO307256B1 (ja)
NZ (1) NZ285910A (ja)
PL (1) PL181099B1 (ja)
RU (1) RU2140916C1 (ja)
WO (1) WO1995031198A1 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5514679A (en) * 1994-05-13 1996-05-07 Sterling Winthrop Inc. Therapeutic phenoxyalklpyridazines and intermediates therefor
AR004012A1 (es) 1995-10-10 1998-09-30 Basf Ag Derivados de acido fenilacetico, procedimientos para su obtencion, su uso para preparar composiciones para combatir animales u hongos nocivos, lascomposiciones asi obtenidas y los procedimientos de aplicacion de dichas composiciones.
AUPQ105499A0 (en) 1999-06-18 1999-07-08 Biota Scientific Management Pty Ltd Antiviral agents
AUPR213700A0 (en) * 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
WO2003020712A1 (en) * 2001-08-29 2003-03-13 Viropharma Incorporated Oxadiazolyl-phenoxyalkylthiadiazoles, compositions thereof and methods for their use as anti-picornaviral agents
EP1981545A2 (en) * 2006-02-09 2008-10-22 Schering Corporation Pharmaceutical formulations
CN103102348B (zh) * 2011-11-14 2016-06-08 上海交通大学 噁二唑类化合物及其制备方法、药物组合物及其用途
WO2017050969A1 (en) * 2015-09-24 2017-03-30 Universite Paris Est Creteil Val De Marne Heterocyclic ho-1 inducers, their use in the treatment of inflammatory or cardiovascular diseases and their process of preparation
CN118084937A (zh) 2018-08-21 2024-05-28 杏林制药株式会社 双环杂芳族环衍生物
CN114014824B (zh) * 2020-12-09 2023-06-13 上海科技大学 一种杂环化合物的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1437781A (en) * 1972-04-04 1976-06-03 Beecham Group Ltd Pyridine derivatives having hypoglycaemic activity
NZ209209A (en) * 1983-08-29 1988-02-12 Sterling Drug Inc Substituted phenyl-aliphatic isoxazole derivatives and pharmaceutical compositions
CA1280753C (en) * 1985-07-02 1991-02-26 Philip Michael Carabateas Process for preparing heterocyclic substituted- phenoxyalkyl isoxazoles and-furans
CA1307222C (en) * 1985-12-16 1992-09-08 Eli Lilly And Company Thiadiazole antiviral agents
JP2504438B2 (ja) * 1986-03-25 1996-06-05 三菱化学株式会社 チアジアゾ−ル誘導体及びこれを有効成分とする殺虫殺ダニ剤
JPH07116183B2 (ja) * 1987-03-31 1995-12-13 三菱化学株式会社 チアジアゾ−ル誘導体及びこれを有効成分とする殺虫殺ダニ剤
GB8807275D0 (en) * 1988-03-26 1988-04-27 Synphar Lab Inc Chemical compounds
JPH01249768A (ja) * 1988-03-30 1989-10-05 Nippon Tokushu Noyaku Seizo Kk Ｎ−置換フエニル−ヘテロ環式化合物及び除草剤
DE3914337A1 (de) * 1989-04-29 1990-10-31 Basf Ag 3(2h)-pyridazinonderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen
NZ233503A (en) * 1989-05-15 1991-06-25 Janssen Pharmaceutica Nv Substituted (thio)morpholinyl and piperazinyl alkylphenol ethers
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
WO1995031438A1 (en) * 1994-05-13 1995-11-23 Sanofi Winthrop, Inc. Therapeutic phenoxyalkylheterocycles
US5514679A (en) * 1994-05-13 1996-05-07 Sterling Winthrop Inc. Therapeutic phenoxyalklpyridazines and intermediates therefor
US5552420A (en) * 1994-05-13 1996-09-03 Sterling Winthrop Inc. Therapeutic phenoxyalkylazoles and phenoxyalkylazines

Also Published As

Publication number Publication date
AU2545895A (en) 1995-12-05
US5750527A (en) 1998-05-12
DE69531491D1 (de) 2003-09-18
CZ333296A3 (en) 1997-08-13
US5650419A (en) 1997-07-22
CA2190130C (en) 2003-06-10
WO1995031198A1 (en) 1995-11-23
EP0759755B1 (en) 2003-08-13
US5821257A (en) 1998-10-13
NO964773L (no) 1996-11-11
ATE247112T1 (de) 2003-08-15
PL317259A1 (en) 1997-04-01
CZ289061B6 (cs) 2001-10-17
US5567719A (en) 1996-10-22
KR970702722A (ko) 1997-06-10
CN1148339A (zh) 1997-04-23
NO964773D0 (no) 1996-11-11
EP0759755A1 (en) 1997-03-05
RU2140916C1 (ru) 1999-11-10
MX9605513A (es) 1998-05-31
CN1095664C (zh) 2002-12-11
EP0759755A4 (en) 1997-05-07
NZ285910A (en) 1997-11-24
AU691923B2 (en) 1998-05-28
US5453433A (en) 1995-09-26
JP4158946B2 (ja) 2008-10-01
KR100383495B1 (ko) 2004-05-20
CA2190130A1 (en) 1995-11-23
PL181099B1 (pl) 2001-05-31
JPH10500136A (ja) 1998-01-06

Similar Documents

Publication Publication Date Title
NO307256B1 (no) Tiadiazoler, farmasoeytisk preparat inneholdende slike forbindelser og deres anvendelse
NO962539D0 (no) 5-(2-imidazolinylamino)benzimidazol-derivater, deres fremstilling og deres anvendelse som -2-adreniceptor-agonister
NO2003005I2 (no) Substituerte isoxazoler, farmasoytisk preparat inneholdende slike forbindelser, fremgangsmâte for deres fremstilling og anvendelse derav, samt mellomprodukter
TNSN01139A1 (en) New thiadiazoles and oxadiazoles and their use as phosphodiesterase -7 inhibitors
MX9401408A (es) Nuevos derivados heterociclicos.
MY128051A (en) Mesylate trihydrate salt of 5-(2-(4-(1, 2-benzisothiazol-3 -yl)-1-piperazinyl)ethyl)-6-chloro-1, 3-dihydro-2-(1h)-indol-2-one (=ziprasidone), its preparation and its use as dopamine d2 antagonist
ATE212991T1 (de) Thiazolidinedione- und oxazolidinedione-derivate mit antidiabetischen, hypolipidämischen und anti hypertensiven eigenschaften
NZ507144A (en) Benzamide derivatives useful for the treatment of diseases mediated by cytokines
DE69404860D1 (de) 1,4,5-triphenyl-pyrazolverbindungen zur behandlumg von entzündungen und entzündungsverwandten störungen
HUP0303281A2 (hu) Benzodiazepinszármazékok, mint GABA A receptor modulátorok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
NZ309151A (en) a 3-substituted cyano or carbamoyl pyrrole derivative and pharmaceutical composition
ATE148108T1 (de) Beta,beta-dimethyl-4-piperidinethanamin-derivat als inhibitoren der cholesterin-biosynthese
CA2190129A1 (en) Therapeutic phenoxyalkylpyridazines and intermediates therefor
RU96123713A (ru) Тиадиазолы и их применение в качестве противопикорнавирусного средства
KR950702417A (ko) 마이코박테륨 투베르쿨로시스에 대해 유용한 5′-인돌리닐 옥사졸리디논(5′-indolinyl oxazolidinones useful against mycobacterium tuberculosis)
ATE192150T1 (de) 6-(2-imidazolinylamino)chinolin-verbindungen als alpha-2-adrenoceptor-antagonisten
MX9701116A (es) Profarmacos de 5-(2-[4-(1,2-benzoisotiazol-3-il)-1-piperazinil]etil)-6-clor o-1,3-dihidro-2h-indol-2-ona.
DE69510802T2 (de) N-[2-(pyrrolidinyl-1)-1-phenylethyl] acetamide als kappa rezeptor agonisten
YU6996A (sh) Upotreba benzotiofena za dobijanje leka
BR0110234A (pt) Agentes anti-hipertensivos e uso
DE602004016331D1 (de) Pentafluoroalkylsulfin-naphthaline und und darauf bezogene modulatoren des östrogenrezeptors
KR890015744A (ko) 과요산헐증치료제
TH25498A (th) สารประกอบเบนโซไธโอฟีน,สารขั้นกลาง,องค์ประกอบและวิธี

Legal Events

Date Code Title Description
MK1K Patent expired