NO305657B1 - 4-substituerte piperidinderivater og farmas°ytisk preparat derav - Google Patents

4-substituerte piperidinderivater og farmas°ytisk preparat derav

Info

Publication number
NO305657B1
NO305657B1 NO960630A NO960630A NO305657B1 NO 305657 B1 NO305657 B1 NO 305657B1 NO 960630 A NO960630 A NO 960630A NO 960630 A NO960630 A NO 960630A NO 305657 B1 NO305657 B1 NO 305657B1
Authority
NO
Norway
Prior art keywords
pharmaceutical preparations
substituted piperidine
piperidine derivatives
derivatives
substituted
Prior art date
Application number
NO960630A
Other languages
English (en)
Norwegian (no)
Other versions
NO960630L (no
NO960630D0 (no
Inventor
Scott Carson Miller
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of NO960630L publication Critical patent/NO960630L/no
Publication of NO960630D0 publication Critical patent/NO960630D0/no
Publication of NO305657B1 publication Critical patent/NO305657B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO960630A 1993-08-17 1996-02-16 4-substituerte piperidinderivater og farmas°ytisk preparat derav NO305657B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939317104A GB9317104D0 (en) 1993-08-17 1993-08-17 Therapeutic heterocycles
PCT/GB1994/001777 WO1995005377A1 (en) 1993-08-17 1994-08-15 Heterocycles useful as neurokinin antagonists

Publications (3)

Publication Number Publication Date
NO960630L NO960630L (no) 1996-02-16
NO960630D0 NO960630D0 (no) 1996-02-16
NO305657B1 true NO305657B1 (no) 1999-07-05

Family

ID=10740632

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960630A NO305657B1 (no) 1993-08-17 1996-02-16 4-substituerte piperidinderivater og farmas°ytisk preparat derav

Country Status (24)

Country Link
US (6) US5567700A (ru)
EP (1) EP0714392B1 (ru)
JP (1) JP3502386B2 (ru)
KR (1) KR100359631B1 (ru)
CN (1) CN1077573C (ru)
AT (1) ATE172971T1 (ru)
AU (1) AU677091B2 (ru)
CA (1) CA2166800C (ru)
CZ (1) CZ285299B6 (ru)
DE (1) DE69414398T2 (ru)
DK (1) DK0714392T3 (ru)
ES (1) ES2123810T3 (ru)
FI (1) FI111253B (ru)
GB (2) GB9317104D0 (ru)
HU (1) HU219586B (ru)
IL (1) IL110672A (ru)
MY (1) MY112102A (ru)
NO (1) NO305657B1 (ru)
NZ (1) NZ269575A (ru)
PL (1) PL178426B1 (ru)
RU (1) RU2153498C2 (ru)
SK (1) SK281232B6 (ru)
WO (1) WO1995005377A1 (ru)
ZA (1) ZA946142B (ru)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583134A (en) * 1992-09-30 1996-12-10 Sanofi 1-azoniabicyclo[2.2.2] octanes and pharmaceutical compositions in which they are present
GB9321557D0 (en) * 1992-11-03 1993-12-08 Zeneca Ltd Carboxamide derivatives
GB9317104D0 (en) * 1993-08-17 1993-09-29 Zeneca Ltd Therapeutic heterocycles
GB9322643D0 (en) * 1993-11-03 1993-12-22 Zeneca Ltd Lactam derivatives
US5589489A (en) * 1993-12-15 1996-12-31 Zeneca Limited Cyclic amide derivatives for treating asthma
GB9408872D0 (en) * 1994-05-03 1994-06-22 Zeneca Ltd Heterocyclic compounds
TW432061B (en) * 1994-08-09 2001-05-01 Pfizer Res & Dev Lactams
US5998444A (en) * 1995-10-24 1999-12-07 Zeneca Ltd. Piperidinyl compounds as NK1 or NK2 antagonists
DE69534213T2 (de) * 1994-10-25 2006-01-12 Astrazeneca Ab Therapeutisch wirksame Heterocyclen
US6008223A (en) * 1994-10-27 1999-12-28 Zeneca Limited Therapeutic compounds
GB9421709D0 (en) * 1994-10-27 1994-12-14 Zeneca Ltd Therapeutic compounds
GB9508786D0 (en) 1995-04-29 1995-06-21 Zeneca Ltd Substituted heterocycles
US5688960A (en) * 1995-05-02 1997-11-18 Schering Corporation Substituted oximes, hydrazones and olefins useful as neurokinin antagonists
US5696267A (en) * 1995-05-02 1997-12-09 Schering Corporation Substituted oximes, hydrazones and olefins as neurokinin antagonists
GB9521781D0 (en) * 1995-10-24 1996-01-03 Merck Sharp & Dohme Therapeutic agents
GB9523526D0 (en) * 1995-11-17 1996-01-17 Zeneca Ltd Therapeutic compounds
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) * 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5789422A (en) * 1996-10-28 1998-08-04 Schering Corporation Substituted arylalkylamines as neurokinin antagonists
PE134599A1 (es) * 1997-11-21 2000-01-07 Schering Corp Oximas sustituidas como antagonistas en neuroquinina
GB9924141D0 (en) * 1998-10-30 1999-12-15 Zeneca Ltd Treatment of gastric asthma
US6063926A (en) * 1998-11-18 2000-05-16 Schering Corporation Substituted oximes as neurokinin antagonists
US6204265B1 (en) 1998-12-23 2001-03-20 Schering Corporation Substituted oximes and hydrazones as neurokinin antagonists
TW533210B (en) * 1998-12-23 2003-05-21 Schering Corp Substituted oximes and hydrazones as neurokinin antagonists
GB0015246D0 (en) * 2000-06-22 2000-08-16 Astrazeneca Ab Method for the treatment of urinary incontinence
SE0103795D0 (sv) 2001-11-02 2001-11-02 Astrazeneca Ab Compounds and method for the treatment of överactive bladder
SE0103668D0 (sv) * 2001-11-02 2001-11-02 Astrazeneca Ab Method for the treatment of overactive blader
US20100189797A1 (en) 2002-06-10 2010-07-29 Julien Mendlewicz Oral antidepressant formulation
TW200508221A (en) 2003-06-13 2005-03-01 Astrazeneca Ab New azetidine compounds
GB0326407D0 (en) * 2003-11-12 2003-12-17 Glaxo Group Ltd Chemical compounds
TWI396686B (zh) 2004-05-21 2013-05-21 Takeda Pharmaceutical 環狀醯胺衍生物、以及其製品和用法
GB0412865D0 (en) * 2004-06-09 2004-07-14 Glaxo Group Ltd Chemical compounds
AR057828A1 (es) 2005-09-29 2007-12-19 Astrazeneca Ab Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
US8106208B2 (en) 2006-05-18 2012-01-31 Albireo Ab Benzamide compounds that act as NK receptor antagonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI97540C (fi) * 1989-11-06 1997-01-10 Sanofi Sa Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi
WO1991009844A1 (en) * 1990-01-04 1991-07-11 Pfizer Inc. Substance p antagonists
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them
FR2676053B1 (fr) * 1991-05-03 1993-08-27 Sanofi Elf Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676054B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676781B1 (fr) * 1991-05-23 1995-03-31 Peugeot Dispositif de refroidissement de l'air de suralimentation d'un moteur a combustion interne d'un vehicule.
FR2688219B1 (fr) * 1992-03-03 1994-07-08 Sanofi Elf Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
GB9321557D0 (en) * 1992-11-03 1993-12-08 Zeneca Ltd Carboxamide derivatives
GB9317104D0 (en) * 1993-08-17 1993-09-29 Zeneca Ltd Therapeutic heterocycles
GB9325074D0 (en) * 1993-12-07 1994-02-02 Zeneca Ltd Bicyclic heterocycles

Also Published As

Publication number Publication date
US6444809B1 (en) 2002-09-03
US5861392A (en) 1999-01-19
MY112102A (en) 2001-04-30
CN1077573C (zh) 2002-01-09
US7053213B2 (en) 2006-05-30
GB9416442D0 (en) 1994-10-05
DE69414398D1 (de) 1998-12-10
DK0714392T3 (da) 2001-02-05
RU2153498C2 (ru) 2000-07-27
CZ43496A3 (en) 1996-05-15
FI960727A (fi) 1996-02-16
US6124279A (en) 2000-09-26
ATE172971T1 (de) 1998-11-15
CA2166800C (en) 2006-06-06
EP0714392A1 (en) 1996-06-05
NZ269575A (en) 1997-11-24
JP3502386B2 (ja) 2004-03-02
JPH09501439A (ja) 1997-02-10
NO960630L (no) 1996-02-16
AU677091B2 (en) 1997-04-10
ES2123810T3 (es) 1999-01-16
DE69414398T2 (de) 1999-05-06
CZ285299B6 (cs) 1999-06-16
HU9503826D0 (en) 1996-02-28
CN1129449A (zh) 1996-08-21
FI111253B (fi) 2003-06-30
WO1995005377A1 (en) 1995-02-23
GB9317104D0 (en) 1993-09-29
SK21096A3 (en) 1997-02-05
PL178426B1 (pl) 2000-04-28
AU7388094A (en) 1995-03-14
HUT75113A (en) 1997-04-28
CA2166800A1 (en) 1995-02-23
IL110672A0 (en) 1994-11-11
NO960630D0 (no) 1996-02-16
KR100359631B1 (ko) 2003-01-24
ZA946142B (en) 1995-02-17
SK281232B6 (sk) 2001-01-18
US20030187255A1 (en) 2003-10-02
US5567700A (en) 1996-10-22
IL110672A (en) 1999-06-20
EP0714392B1 (en) 1998-11-04
FI960727A0 (fi) 1996-02-16
US5990130A (en) 1999-11-23
HU219586B (hu) 2001-05-28
PL313075A1 (en) 1996-05-27

Similar Documents

Publication Publication Date Title
NO305657B1 (no) 4-substituerte piperidinderivater og farmas°ytisk preparat derav
NO306678B1 (no) Pyrrolopyrimidiner som CRF-antagonister og farmasöytisk preparat
FI945706A (fi) Proteiinikinaasi C-inhibiittoreita
NO303780B1 (no) Nye 4-arylpiperaziner og 4-arylpiperidiner, sammensetning inneholdende dem samt deres anvendelse til fremstilling av terapeutikum
NO883229D0 (no) Nye benzimidazolderivater, fremgangsmaate for deres fremstilling og farmasoeytisk preparat inneholdende slike derivater.
NO178398C (no) Piperidin derivater og farmasöytisk formulering
ATE352543T1 (de) Ein dioxino(2,3-g)chinolin-9-carbonsäure derivat als nk3 rezeptor antagonist
DK53285D0 (da) (-)-trans-4(4-fluorphenyl)-3-(4-methoxyphenoxy)-methylpiperidin, farmaceutisk acceptable syreadditionssalte heraf og farmaceutisk praeparat indeholdende samme
NO971625L (no) Nye peptider med immunomodulatoriske effekter
TR200000737T2 (tr) İkame edilmiş kroman türevleri.
DK122391D0 (da) Terapeutisk aktiv, substitueret benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme
SE9702305D0 (sv) New thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives
TR199700956T1 (xx) Indazolkarboksamidler.
DK0506778T3 (da) Substituerede 4-phenyl-4-piperidincarboxamider med både lokal anæstetisk og analgetisk virkning samt fremgangsmåder til deres fremstilling
DK23289D0 (da) Disubstituerede pyridinderivater, fremgangsmaade og mellemprodukter til deres fremstilling samt deres anvendelse
NO20001934L (no) 3-Substituerte tetrahydropyridopyrimidinon-derivater, deres fremstilling og anvendelse
NO306400B1 (no) N-substituerte azabicykloheptan-derivater, anvendelse derav og farmasöytisk preparat
EE200100520A (et) N-(2-fenüül-4-aminobutüül)-1-naftamiidid neurokiniin-1-retseptori antagonistidena
IL102334A0 (en) 2-(1-piperidyl)ethanol derivatives,their preparation and their therapeutic application
FI890864A0 (fi) Anvaendning av 1,4-dihydropyridinderivat.
TR199901385T2 (xx) Piperidin t�revleri.
NO307512B1 (no) Nye indolforbindelser, farmasøytisk preparat inneholdende slike forbindelser, og deres anvendelse
NZ234150A (en) Bis (benzyl pyrrolidine) derivatives, benzyl pyrrolidine intermediates and pharmaceutical compositions for use as dopamine antagonists
TR200000916T2 (tr) İkameli piperidin türevleri.
ZA924789B (en) 2-(1-piperidyl)ethanol derivatives,their preparation and their therapeutic application

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees