FI960727A - Neurokiniiniantagonisteina käyttökelpoiset heterosyklit - Google Patents

Neurokiniiniantagonisteina käyttökelpoiset heterosyklit Download PDF

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Publication number
FI960727A
FI960727A FI960727A FI960727A FI960727A FI 960727 A FI960727 A FI 960727A FI 960727 A FI960727 A FI 960727A FI 960727 A FI960727 A FI 960727A FI 960727 A FI960727 A FI 960727A
Authority
FI
Finland
Prior art keywords
neurokinin antagonists
heterocycles useful
heterocycles
useful
neurokinin
Prior art date
Application number
FI960727A
Other languages
English (en)
Swedish (sv)
Other versions
FI111253B (fi
FI960727A0 (fi
Inventor
Scott Garson Miller
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of FI960727A publication Critical patent/FI960727A/fi
Publication of FI960727A0 publication Critical patent/FI960727A0/fi
Application granted granted Critical
Publication of FI111253B publication Critical patent/FI111253B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
FI960727A 1993-08-17 1996-02-16 Menetelmä terapeuttisesti käyttökelpoisten heterosyklisten yhdisteiden valmistamiseksi FI111253B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9317104 1993-08-17
GB939317104A GB9317104D0 (en) 1993-08-17 1993-08-17 Therapeutic heterocycles
GB9401777 1994-08-15
PCT/GB1994/001777 WO1995005377A1 (en) 1993-08-17 1994-08-15 Heterocycles useful as neurokinin antagonists

Publications (3)

Publication Number Publication Date
FI960727A true FI960727A (fi) 1996-02-16
FI960727A0 FI960727A0 (fi) 1996-02-16
FI111253B FI111253B (fi) 2003-06-30

Family

ID=10740632

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960727A FI111253B (fi) 1993-08-17 1996-02-16 Menetelmä terapeuttisesti käyttökelpoisten heterosyklisten yhdisteiden valmistamiseksi

Country Status (24)

Country Link
US (6) US5567700A (fi)
EP (1) EP0714392B1 (fi)
JP (1) JP3502386B2 (fi)
KR (1) KR100359631B1 (fi)
CN (1) CN1077573C (fi)
AT (1) ATE172971T1 (fi)
AU (1) AU677091B2 (fi)
CA (1) CA2166800C (fi)
CZ (1) CZ285299B6 (fi)
DE (1) DE69414398T2 (fi)
DK (1) DK0714392T3 (fi)
ES (1) ES2123810T3 (fi)
FI (1) FI111253B (fi)
GB (2) GB9317104D0 (fi)
HU (1) HU219586B (fi)
IL (1) IL110672A (fi)
MY (1) MY112102A (fi)
NO (1) NO305657B1 (fi)
NZ (1) NZ269575A (fi)
PL (1) PL178426B1 (fi)
RU (1) RU2153498C2 (fi)
SK (1) SK281232B6 (fi)
WO (1) WO1995005377A1 (fi)
ZA (1) ZA946142B (fi)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583134A (en) * 1992-09-30 1996-12-10 Sanofi 1-azoniabicyclo[2.2.2] octanes and pharmaceutical compositions in which they are present
GB9321557D0 (en) * 1992-11-03 1993-12-08 Zeneca Ltd Carboxamide derivatives
GB9317104D0 (en) * 1993-08-17 1993-09-29 Zeneca Ltd Therapeutic heterocycles
GB9322643D0 (en) * 1993-11-03 1993-12-22 Zeneca Ltd Lactam derivatives
US5589489A (en) * 1993-12-15 1996-12-31 Zeneca Limited Cyclic amide derivatives for treating asthma
GB9408872D0 (en) * 1994-05-03 1994-06-22 Zeneca Ltd Heterocyclic compounds
TW432061B (en) * 1994-08-09 2001-05-01 Pfizer Res & Dev Lactams
US5998444A (en) * 1995-10-24 1999-12-07 Zeneca Ltd. Piperidinyl compounds as NK1 or NK2 antagonists
DE69534213T2 (de) * 1994-10-25 2006-01-12 Astrazeneca Ab Therapeutisch wirksame Heterocyclen
US6008223A (en) * 1994-10-27 1999-12-28 Zeneca Limited Therapeutic compounds
GB9421709D0 (en) * 1994-10-27 1994-12-14 Zeneca Ltd Therapeutic compounds
GB9508786D0 (en) 1995-04-29 1995-06-21 Zeneca Ltd Substituted heterocycles
US5688960A (en) * 1995-05-02 1997-11-18 Schering Corporation Substituted oximes, hydrazones and olefins useful as neurokinin antagonists
US5696267A (en) * 1995-05-02 1997-12-09 Schering Corporation Substituted oximes, hydrazones and olefins as neurokinin antagonists
GB9521781D0 (en) * 1995-10-24 1996-01-03 Merck Sharp & Dohme Therapeutic agents
GB9523526D0 (en) * 1995-11-17 1996-01-17 Zeneca Ltd Therapeutic compounds
US5998439A (en) 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
US5789422A (en) * 1996-10-28 1998-08-04 Schering Corporation Substituted arylalkylamines as neurokinin antagonists
PE134599A1 (es) * 1997-11-21 2000-01-07 Schering Corp Oximas sustituidas como antagonistas en neuroquinina
GB9924141D0 (en) * 1998-10-30 1999-12-15 Zeneca Ltd Treatment of gastric asthma
US6063926A (en) * 1998-11-18 2000-05-16 Schering Corporation Substituted oximes as neurokinin antagonists
AR021968A1 (es) * 1998-12-23 2002-09-04 Schering Corp Oximas e hidrazonas sustituidas como antagonistas de neuroquinina
US6204265B1 (en) 1998-12-23 2001-03-20 Schering Corporation Substituted oximes and hydrazones as neurokinin antagonists
GB0015246D0 (en) * 2000-06-22 2000-08-16 Astrazeneca Ab Method for the treatment of urinary incontinence
SE0103795D0 (sv) * 2001-11-02 2001-11-02 Astrazeneca Ab Compounds and method for the treatment of överactive bladder
SE0103668D0 (sv) * 2001-11-02 2001-11-02 Astrazeneca Ab Method for the treatment of overactive blader
US20100189797A1 (en) 2002-06-10 2010-07-29 Julien Mendlewicz Oral antidepressant formulation
TW200508221A (en) 2003-06-13 2005-03-01 Astrazeneca Ab New azetidine compounds
GB0326407D0 (en) * 2003-11-12 2003-12-17 Glaxo Group Ltd Chemical compounds
TWI396686B (zh) 2004-05-21 2013-05-21 Takeda Pharmaceutical 環狀醯胺衍生物、以及其製品和用法
GB0412865D0 (en) * 2004-06-09 2004-07-14 Glaxo Group Ltd Chemical compounds
AR057828A1 (es) 2005-09-29 2007-12-19 Astrazeneca Ab Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
US8106208B2 (en) * 2006-05-18 2012-01-31 Albireo Ab Benzamide compounds that act as NK receptor antagonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI97540C (fi) * 1989-11-06 1997-01-10 Sanofi Sa Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi
WO1991009844A1 (en) * 1990-01-04 1991-07-11 Pfizer Inc. Substance p antagonists
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them
FR2676053B1 (fr) * 1991-05-03 1993-08-27 Sanofi Elf Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676054B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2676781B1 (fr) * 1991-05-23 1995-03-31 Peugeot Dispositif de refroidissement de l'air de suralimentation d'un moteur a combustion interne d'un vehicule.
FR2688219B1 (fr) * 1992-03-03 1994-07-08 Sanofi Elf Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant.
GB9321557D0 (en) * 1992-11-03 1993-12-08 Zeneca Ltd Carboxamide derivatives
GB9317104D0 (en) * 1993-08-17 1993-09-29 Zeneca Ltd Therapeutic heterocycles
GB9325074D0 (en) * 1993-12-07 1994-02-02 Zeneca Ltd Bicyclic heterocycles

Also Published As

Publication number Publication date
ES2123810T3 (es) 1999-01-16
CA2166800A1 (en) 1995-02-23
CZ285299B6 (cs) 1999-06-16
DE69414398T2 (de) 1999-05-06
CA2166800C (en) 2006-06-06
US6444809B1 (en) 2002-09-03
US7053213B2 (en) 2006-05-30
AU7388094A (en) 1995-03-14
SK21096A3 (en) 1997-02-05
DE69414398D1 (de) 1998-12-10
DK0714392T3 (da) 2001-02-05
US6124279A (en) 2000-09-26
NZ269575A (en) 1997-11-24
CN1077573C (zh) 2002-01-09
ZA946142B (en) 1995-02-17
US20030187255A1 (en) 2003-10-02
KR100359631B1 (ko) 2003-01-24
MY112102A (en) 2001-04-30
IL110672A (en) 1999-06-20
HUT75113A (en) 1997-04-28
AU677091B2 (en) 1997-04-10
NO960630L (no) 1996-02-16
GB9416442D0 (en) 1994-10-05
JP3502386B2 (ja) 2004-03-02
GB9317104D0 (en) 1993-09-29
HU219586B (hu) 2001-05-28
CZ43496A3 (en) 1996-05-15
IL110672A0 (en) 1994-11-11
EP0714392B1 (en) 1998-11-04
FI111253B (fi) 2003-06-30
US5861392A (en) 1999-01-19
PL313075A1 (en) 1996-05-27
HU9503826D0 (en) 1996-02-28
EP0714392A1 (en) 1996-06-05
NO305657B1 (no) 1999-07-05
SK281232B6 (sk) 2001-01-18
RU2153498C2 (ru) 2000-07-27
ATE172971T1 (de) 1998-11-15
US5990130A (en) 1999-11-23
CN1129449A (zh) 1996-08-21
US5567700A (en) 1996-10-22
PL178426B1 (pl) 2000-04-28
JPH09501439A (ja) 1997-02-10
WO1995005377A1 (en) 1995-02-23
NO960630D0 (no) 1996-02-16
FI960727A0 (fi) 1996-02-16

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