NO305477B1 - Nye 3,3-difenylpropylaminer, farmas°ytiske preparater inneholdende slike forbindelser, og deres anvendelse - Google Patents

Nye 3,3-difenylpropylaminer, farmas°ytiske preparater inneholdende slike forbindelser, og deres anvendelse

Info

Publication number
NO305477B1
NO305477B1 NO951775A NO951775A NO305477B1 NO 305477 B1 NO305477 B1 NO 305477B1 NO 951775 A NO951775 A NO 951775A NO 951775 A NO951775 A NO 951775A NO 305477 B1 NO305477 B1 NO 305477B1
Authority
NO
Norway
Prior art keywords
compounds
diphenylpropylamines
methyl
formula
new
Prior art date
Application number
NO951775A
Other languages
English (en)
Norwegian (no)
Other versions
NO951775D0 (no
NO951775L (no
Inventor
Rolf Arne Johansson
Pinchas Moses
Lisbeth Nilvebrant
Bengt Ke Sparf
Original Assignee
Pharmacia & Upjohn Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20387730&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO305477(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab
Publication of NO951775D0 publication Critical patent/NO951775D0/no
Publication of NO951775L publication Critical patent/NO951775L/no
Publication of NO305477B1 publication Critical patent/NO305477B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Luminescent Compositions (AREA)
  • Photoreceptors In Electrophotography (AREA)
NO951775A 1992-11-06 1995-05-05 Nye 3,3-difenylpropylaminer, farmas°ytiske preparater inneholdende slike forbindelser, og deres anvendelse NO305477B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9203318A SE9203318D0 (sv) 1992-11-06 1992-11-06 Novel 3,3-diphenylpropylamines, their use and preparation
PCT/SE1993/000927 WO1994011337A1 (en) 1992-11-06 1993-11-05 Novel 3,3-diphenylpropylamines, their use and preparation

Publications (3)

Publication Number Publication Date
NO951775D0 NO951775D0 (no) 1995-05-05
NO951775L NO951775L (no) 1995-05-05
NO305477B1 true NO305477B1 (no) 1999-06-07

Family

ID=20387730

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951775A NO305477B1 (no) 1992-11-06 1995-05-05 Nye 3,3-difenylpropylaminer, farmas°ytiske preparater inneholdende slike forbindelser, og deres anvendelse

Country Status (15)

Country Link
US (4) USRE39667E1 (de)
EP (1) EP0667852B1 (de)
JP (1) JP3343256B2 (de)
AT (1) ATE164828T1 (de)
AU (1) AU672458B2 (de)
CA (1) CA2148827C (de)
DE (1) DE69317898T2 (de)
DK (1) DK0667852T3 (de)
ES (1) ES2117155T3 (de)
FI (1) FI120256B (de)
HK (1) HK1006349A1 (de)
HU (1) HU224916B1 (de)
NO (1) NO305477B1 (de)
SE (1) SE9203318D0 (de)
WO (1) WO1994011337A1 (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
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CN1104239C (zh) * 1996-12-02 2003-04-02 杏林制药株式会社 新颖的n－取代的吡咯烷衍生物及其制备方法
SE9701144D0 (sv) 1997-03-27 1997-03-27 Pharmacia & Upjohn Ab Novel compounds, their use and preparation
EP0957073A1 (de) * 1998-05-12 1999-11-17 Schwarz Pharma Ag 3,3-Diphenylpropylaminderivate
ME00850B (me) 1998-08-27 2008-08-07 Pfizer Health Ab Nove perle sa kontrolisanim oslobađanjem, postupak za njihovu proizvodnju i višestruka jedinična formulacija koja ih sadrži
DE60021749T2 (de) 1999-11-11 2006-04-20 Pfizer Health Ab Pharmazeutische formulierung enthaltend tolterodin sowie ihre verwendung
DE19955190A1 (de) * 1999-11-16 2001-06-21 Sanol Arznei Schwarz Gmbh Stabile Salze neuartiger Derivate von 3,3-Diphenylpropylaminen
SE9904850D0 (sv) * 1999-12-30 1999-12-30 Pharmacia & Upjohn Ab Novel process and intermediates
WO2001070689A1 (fr) 2000-03-24 2001-09-27 Meiji Seika Kaisha, Ltd. DERIVES DE LA DIPHENYLALKYLAMINE UTILES COMME AGONISTES DU RECEPTEUR DE L'OPIOIDE $g(d)
DE10028443C1 (de) * 2000-06-14 2002-05-29 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von 3,3-Diarylpropylaminen, (R,S)- und (R)-4-Phenyl-2-chromanon-6-carbonsäure sowie (R)-4-Phenyl-2-chromanon-carbonsäure-cinchonidinsalz und deren Verwendung zur Herstellung eines rechtsdrehenden Hydroxybenzylalkohols und von pharmazeutischen Zusammensetzungen
DE10033016A1 (de) 2000-07-07 2002-01-24 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von 3,3-Diarylpropylaminen
PE20020547A1 (es) 2000-10-24 2002-06-12 Upjohn Co Uso de la tolterodina en tratamientos del asma
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US20030027856A1 (en) * 2001-06-29 2003-02-06 Aberg A.K. Gunnar Tolterodine metabolites
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US7825132B2 (en) 2002-08-23 2010-11-02 Novartis Vaccines And Diagnostics, Inc. Inhibition of FGFR3 and treatment of multiple myeloma
KR20050075005A (ko) 2002-11-13 2005-07-19 카이론 코포레이션 암을 치료하는 방법 및 관련 방법
DE10315917A1 (de) * 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
EP1618091A1 (de) * 2003-04-09 2006-01-25 Ranbaxy Laboratories, Ltd. Substituierte azabicyclohexanderivate als antagonisten von muscarinrezeptoren
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ES2235648B1 (es) * 2003-12-22 2006-11-01 Ragactives, S.L. Procedimiento para la obtencion de tolterodina.
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IES20060424A2 (en) 2006-06-08 2007-10-31 Schwarz Pharma Ltd Accelerated synthesis of (3-Diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)phenol and its phenolic monoesters
US7985873B2 (en) 2006-06-09 2011-07-26 Ucb Pharma Gmbh Synthesis of phenolic esters of hydroxymethyl phenols
IES20060435A2 (en) 2006-06-12 2007-12-12 Schwarz Pharma Ltd Shortened synthesis using paraformaldehyde or trioxane
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WO2007147547A1 (en) * 2006-06-20 2007-12-27 Lek Pharmaceuticals D.D. Process for preparation of 3-(2-hydroxy-5-substituted phenyl)-n-alkyl-3-phenylpropylamines
WO2009037569A2 (en) * 2007-09-21 2009-03-26 Actavis Group Ptc Ehf An improved process for the preparation of fesoterodine
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US20090214665A1 (en) * 2008-02-26 2009-08-27 Lai Felix S Controlled Release Muscarinic Receptor Antagonist Formulation
KR20120014583A (ko) * 2009-05-11 2012-02-17 라티오팜 게엠베하 타르타르산 염 형태의 데스페소테로딘
IT1394219B1 (it) 2009-05-15 2012-06-01 Chemi Spa Metodo di preparazione di fesoterodina fumarato di elevata purezza.
IT1394217B1 (it) 2009-05-15 2012-06-01 Chemi Spa Metodo di preparazione di fesoterodina e/o fesoterodina fumarato.
ES2456866T3 (es) 2009-07-27 2014-04-23 Crystal Pharma, S.A.U. Procedimiento para la obtención de 3,3-difenilpropilaminas
IT1396373B1 (it) 2009-10-29 2012-11-19 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina.
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TWI590821B (zh) 2011-01-18 2017-07-11 輝瑞有限公司 固體分子分散液
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US9315450B2 (en) 2012-06-14 2016-04-19 Ratiopharm Gmbh Desfesoterodine salts
ITMI20121232A1 (it) 2012-07-16 2014-01-17 Cambrex Profarmaco Milano Srl Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati
GB201402556D0 (en) 2014-02-13 2014-04-02 Crystec Ltd Improvements relating to inhalable particles
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CN110372571B (zh) 2018-04-12 2022-11-15 中国科学院大连化学物理研究所 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物

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Also Published As

Publication number Publication date
CA2148827C (en) 2005-01-04
NO951775D0 (no) 1995-05-05
HK1006349A1 (en) 1999-02-19
WO1994011337A1 (en) 1994-05-26
NO951775L (no) 1995-05-05
DE69317898T2 (de) 1998-10-15
AU5438094A (en) 1994-06-08
DE69317898D1 (de) 1998-05-14
FI952179A0 (fi) 1995-05-05
HU9501329D0 (en) 1995-06-28
ATE164828T1 (de) 1998-04-15
JP3343256B2 (ja) 2002-11-11
US5559269A (en) 1996-09-24
CA2148827A1 (en) 1994-05-26
SE9203318D0 (sv) 1992-11-06
AU672458B2 (en) 1996-10-03
ES2117155T3 (es) 1998-08-01
US5686464A (en) 1997-11-11
USRE40851E1 (en) 2009-07-14
EP0667852A1 (de) 1995-08-23
JPH08503208A (ja) 1996-04-09
EP0667852B1 (de) 1998-04-08
HUT72742A (en) 1996-05-28
FI952179A (fi) 1995-05-05
HU224916B1 (en) 2006-04-28
DK0667852T3 (da) 1999-01-11
USRE39667E1 (en) 2007-05-29
FI120256B (fi) 2009-08-31

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