NO305290B1 - FremgangsmÕte til fremstilling av rekombinant human interleukin-1-inhibitor - Google Patents
FremgangsmÕte til fremstilling av rekombinant human interleukin-1-inhibitor Download PDFInfo
- Publication number
- NO305290B1 NO305290B1 NO922138A NO922138A NO305290B1 NO 305290 B1 NO305290 B1 NO 305290B1 NO 922138 A NO922138 A NO 922138A NO 922138 A NO922138 A NO 922138A NO 305290 B1 NO305290 B1 NO 305290B1
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- plasmid
- sepharose
- ion exchange
- gene
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
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- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44265289A | 1989-11-29 | 1989-11-29 | |
| PCT/US1990/006979 WO1991008285A1 (en) | 1989-11-29 | 1990-11-29 | Production of recombinant human interleukin-1 inhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO922138D0 NO922138D0 (no) | 1992-05-29 |
| NO922138L NO922138L (no) | 1992-05-29 |
| NO305290B1 true NO305290B1 (no) | 1999-05-03 |
Family
ID=23757611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO922138A NO305290B1 (no) | 1989-11-29 | 1992-05-29 | FremgangsmÕte til fremstilling av rekombinant human interleukin-1-inhibitor |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5453490A (fi) |
| EP (1) | EP0502956B1 (fi) |
| JP (1) | JP3014007B2 (fi) |
| KR (1) | KR0182819B1 (fi) |
| AT (1) | ATE152172T1 (fi) |
| AU (1) | AU651955B2 (fi) |
| BR (1) | BR9007883A (fi) |
| CA (1) | CA2068320C (fi) |
| DE (1) | DE69030582T2 (fi) |
| DK (1) | DK0502956T3 (fi) |
| ES (1) | ES2103305T3 (fi) |
| FI (1) | FI104733B (fi) |
| GR (1) | GR3024031T3 (fi) |
| HK (1) | HK1006856A1 (fi) |
| HU (1) | HUT64582A (fi) |
| NO (1) | NO305290B1 (fi) |
| WO (1) | WO1991008285A1 (fi) |
Families Citing this family (46)
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| US6858409B1 (en) | 1988-05-27 | 2005-02-22 | Amgen Inc. | Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors |
| US5075222A (en) | 1988-05-27 | 1991-12-24 | Synergen, Inc. | Interleukin-1 inhibitors |
| US6159460A (en) * | 1988-05-27 | 2000-12-12 | Amgen Inc. | Method for treating interleukin-1 mediated diseases |
| US6552170B1 (en) * | 1990-04-06 | 2003-04-22 | Amgen Inc. | PEGylation reagents and compounds formed therewith |
| US5786331A (en) * | 1994-02-02 | 1998-07-28 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-1 receptor |
| US5608035A (en) * | 1994-02-02 | 1997-03-04 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-1 receptor |
| US5880096A (en) * | 1994-02-02 | 1999-03-09 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-1 receptor |
| US5861476A (en) * | 1994-02-02 | 1999-01-19 | Affymax Technologies N.V. | Peptides and compounds that bind to the IL-1 receptor |
| US5837495A (en) * | 1994-10-13 | 1998-11-17 | Applied Research Systems Ars Holding N.V. | DNA encoding interleukin-1 antagonist |
| US5981713A (en) * | 1994-10-13 | 1999-11-09 | Applied Research Systems Ars Holding N.V. | Antibodies to intereleukin-1 antagonists |
| IT1270662B (it) * | 1994-10-13 | 1997-05-07 | Applied Research Systems | Antagonista della interleuchina-1 |
| TW555765B (en) * | 1996-07-09 | 2003-10-01 | Amgen Inc | Low molecular weight soluble tumor necrosis factor type-I and type-II proteins |
| ES2312179T3 (es) * | 1996-12-06 | 2009-02-16 | Amgen Inc. | Terapia combinada que utiliza un inhibidor del il-1 para el tratamiento de enfermedades mediadas por el il-1. |
| US6294170B1 (en) | 1997-08-08 | 2001-09-25 | Amgen Inc. | Composition and method for treating inflammatory diseases |
| US6013253A (en) * | 1997-08-15 | 2000-01-11 | Amgen, Inc. | Treatment of multiple sclerosis using consensus interferon and IL-1 receptor antagonist |
| US6660843B1 (en) * | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| US8106098B2 (en) | 1999-08-09 | 2012-01-31 | The General Hospital Corporation | Protein conjugates with a water-soluble biocompatible, biodegradable polymer |
| TR201809008T4 (tr) | 2001-06-26 | 2018-07-23 | Amgen Fremont Inc | Opgl ye karşi antikorlar. |
| US20030191056A1 (en) | 2002-04-04 | 2003-10-09 | Kenneth Walker | Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins |
| DK1572946T3 (da) | 2002-09-06 | 2012-07-02 | Amgen Inc | Terapeutisk humant monoklonalt anti-IL-1R1-antistof |
| CA2557910C (en) | 2004-04-02 | 2012-05-29 | Amgen Inc. | Methods of reducing aggregation of il-1ra |
| TW200736277A (en) | 2005-11-14 | 2007-10-01 | Amgen Inc | RANKL antibody-PTH/PTHrP chimeric molecules |
| US20070248653A1 (en) * | 2006-04-20 | 2007-10-25 | Cochrum Kent C | Hemostatic compositions and methods for controlling bleeding |
| US7833527B2 (en) | 2006-10-02 | 2010-11-16 | Amgen Inc. | Methods of treating psoriasis using IL-17 Receptor A antibodies |
| US10105441B2 (en) * | 2007-08-16 | 2018-10-23 | The Schepens Eye Research Institute, Inc. | Method for inhibiting or reducing dry eye disease by IL-1Ra |
| EP2217258B1 (en) | 2007-11-14 | 2014-03-26 | General Regeneratives Limited | Use of interleukin-1 receptor antagonist as a myeloprotective agent |
| EP2259774B1 (en) | 2008-02-27 | 2012-12-12 | Biomet Biologics, LLC | Methods and compositions for delivering interleukin-1 receptor antagonist |
| TW201117824A (en) | 2009-10-12 | 2011-06-01 | Amgen Inc | Use of IL-17 receptor a antigen binding proteins |
| CN101690801B (zh) | 2009-10-26 | 2012-08-01 | 上海交通大学 | 白细胞介素-1受体拮抗剂的用途及其药物组合物 |
| KR102080704B1 (ko) | 2010-07-29 | 2020-02-24 | 세센 바이오, 아이엔씨. | 키메라 il-1 수용체 유형 i 항진제 및 길항제들 |
| WO2013016220A1 (en) | 2011-07-22 | 2013-01-31 | Amgen Inc. | Il-17 receptor a is required for il-17c biology |
| WO2013019652A1 (en) * | 2011-07-29 | 2013-02-07 | Eleven Biotherapeutics, Inc. | Purified proteins |
| EP2851429B1 (en) | 2012-05-18 | 2019-07-24 | Adda Biotech Inc. | Protein and protein conjugate for diabetes treatment, and applications thereof |
| JP6450364B2 (ja) | 2013-03-13 | 2019-01-09 | セセン バイオ， インコーポレイテッド | 眼送達のためのキメラサイトカイン製剤 |
| US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
| US20140271589A1 (en) | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Treatment of collagen defects using protein solutions |
| US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
| US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
| US9758806B2 (en) | 2013-03-15 | 2017-09-12 | Biomet Biologics, Llc | Acellular compositions for treating inflammatory disorders |
| AU2014345511A1 (en) | 2013-11-11 | 2016-05-12 | Ascendis Pharma A/S | Relaxin prodrugs |
| US9833474B2 (en) | 2013-11-26 | 2017-12-05 | Biomet Biologies, LLC | Methods of mediating macrophage phenotypes |
| WO2015191783A2 (en) | 2014-06-10 | 2015-12-17 | Abbvie Inc. | Biomarkers for inflammatory disease and methods of using same |
| WO2018022982A1 (en) | 2016-07-29 | 2018-02-01 | Trustees Of Boston University | Age-associated clonal hematopoiesis accelerates cardio-metabolic disease development |
| US11285196B2 (en) | 2017-03-13 | 2022-03-29 | Eslam Abbas Baseuny | Multivalent biologic constructs for inducing a therapeutic modulation of cellular response and uses thereof |
| EP3836954A1 (en) | 2018-08-13 | 2021-06-23 | Iltoo Pharma | Combination of interleukin-2 with an interleukin 1 inhibitor, conjugates and therapeutic uses thereof |
| WO2023222565A1 (en) | 2022-05-16 | 2023-11-23 | Institut National de la Santé et de la Recherche Médicale | Methods for assessing the exhaustion of hematopoietic stems cells induced by chronic inflammation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2220662A (en) * | 1987-08-26 | 1990-01-17 | Biogen Inc | Biological materials,processes for producing biological materials and for using such materials in therapy |
| KR0148009B1 (ko) * | 1988-05-27 | 1998-08-01 | 그래고리 비. 아보트 | 인터루킨-1 억제제 |
| US5075222A (en) * | 1988-05-27 | 1991-12-24 | Synergen, Inc. | Interleukin-1 inhibitors |
| WO1991017184A1 (en) * | 1990-04-27 | 1991-11-14 | The Upjohn Company | Modified interleukin-1 inhibitors |
| JPH05506986A (ja) * | 1990-05-01 | 1993-10-14 | カイロン コーポレイション | インターロイキン―１拮抗物質及びその利用 |
-
1990
- 1990-11-29 HU HU9201777A patent/HUT64582A/hu unknown
- 1990-11-29 ES ES91900515T patent/ES2103305T3/es not_active Expired - Lifetime
- 1990-11-29 DE DE69030582T patent/DE69030582T2/de not_active Expired - Lifetime
- 1990-11-29 CA CA002068320A patent/CA2068320C/en not_active Expired - Lifetime
- 1990-11-29 AT AT91900515T patent/ATE152172T1/de not_active IP Right Cessation
- 1990-11-29 WO PCT/US1990/006979 patent/WO1991008285A1/en active IP Right Grant
- 1990-11-29 BR BR909007883A patent/BR9007883A/pt not_active Application Discontinuation
- 1990-11-29 JP JP3501112A patent/JP3014007B2/ja not_active Expired - Lifetime
- 1990-11-29 AU AU69007/91A patent/AU651955B2/en not_active Expired
- 1990-11-29 DK DK91900515.7T patent/DK0502956T3/da active
- 1990-11-29 EP EP91900515A patent/EP0502956B1/en not_active Expired - Lifetime
-
1992
- 1992-05-27 FI FI922434A patent/FI104733B/fi active
- 1992-05-29 NO NO922138A patent/NO305290B1/no not_active IP Right Cessation
- 1992-05-29 KR KR1019920701272A patent/KR0182819B1/ko not_active IP Right Cessation
-
1994
- 1994-08-30 US US08/298,180 patent/US5453490A/en not_active Expired - Lifetime
-
1997
- 1997-07-09 GR GR970401686T patent/GR3024031T3/el unknown
-
1998
- 1998-06-22 HK HK98105919A patent/HK1006856A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO922138D0 (no) | 1992-05-29 |
| JP3014007B2 (ja) | 2000-02-28 |
| KR0182819B1 (en) | 1999-04-01 |
| CA2068320C (en) | 2000-10-17 |
| FI922434A (fi) | 1992-05-27 |
| WO1991008285A1 (en) | 1991-06-13 |
| AU651955B2 (en) | 1994-08-11 |
| AU6900791A (en) | 1991-06-26 |
| KR920703792A (ko) | 1992-12-18 |
| JPH05503007A (ja) | 1993-05-27 |
| ATE152172T1 (de) | 1997-05-15 |
| CA2068320A1 (en) | 1991-05-30 |
| HUT64582A (en) | 1994-01-28 |
| HK1006856A1 (en) | 1999-03-19 |
| HU9201777D0 (en) | 1992-12-28 |
| BR9007883A (pt) | 1992-09-29 |
| ES2103305T3 (es) | 1997-09-16 |
| EP0502956A1 (en) | 1992-09-16 |
| FI104733B (fi) | 2000-03-31 |
| DK0502956T3 (da) | 1997-10-20 |
| US5453490A (en) | 1995-09-26 |
| FI922434A0 (fi) | 1992-05-27 |
| GR3024031T3 (en) | 1997-10-31 |
| EP0502956A4 (en) | 1992-12-09 |
| NO922138L (no) | 1992-05-29 |
| EP0502956B1 (en) | 1997-04-23 |
| DE69030582T2 (de) | 1998-06-25 |
| DE69030582D1 (de) | 1997-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |