NO305250B1 - Triazolbenzazepinderivater med antiallergisk virkning - Google Patents
Triazolbenzazepinderivater med antiallergisk virkningInfo
- Publication number
- NO305250B1 NO305250B1 NO952198A NO952198A NO305250B1 NO 305250 B1 NO305250 B1 NO 305250B1 NO 952198 A NO952198 A NO 952198A NO 952198 A NO952198 A NO 952198A NO 305250 B1 NO305250 B1 NO 305250B1
- Authority
- NO
- Norway
- Prior art keywords
- 4alkyl
- pct
- substituted
- hydroxycarbonyl
- alk
- Prior art date
Links
- -1 Triazole benzazepine derivatives Chemical class 0.000 title 1
- 230000003266 anti-allergic effect Effects 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 150000002431 hydrogen Chemical group 0.000 abstract 4
- 125000001475 halogen functional group Chemical group 0.000 abstract 3
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical group O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP92203776 | 1992-12-04 | ||
| PCT/EP1993/003320 WO1994013671A1 (en) | 1992-12-04 | 1993-11-25 | Antiallergic triazolobenzazepine derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO952198D0 NO952198D0 (no) | 1995-06-02 |
| NO952198L NO952198L (no) | 1995-08-03 |
| NO305250B1 true NO305250B1 (no) | 1999-04-26 |
Family
ID=8211104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO952198A NO305250B1 (no) | 1992-12-04 | 1995-06-02 | Triazolbenzazepinderivater med antiallergisk virkning |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5932569A (ja) |
| EP (1) | EP0675887B1 (ja) |
| JP (1) | JP3572074B2 (ja) |
| KR (1) | KR100251893B1 (ja) |
| AT (1) | ATE236164T1 (ja) |
| AU (1) | AU676701B2 (ja) |
| CA (1) | CA2150806C (ja) |
| DE (1) | DE69332830T2 (ja) |
| ES (1) | ES2196020T3 (ja) |
| FI (1) | FI952722A0 (ja) |
| HU (1) | HU223464B1 (ja) |
| NO (1) | NO305250B1 (ja) |
| NZ (1) | NZ258551A (ja) |
| PL (1) | PL176593B1 (ja) |
| RU (1) | RU2126802C1 (ja) |
| WO (1) | WO1994013671A1 (ja) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT675889E (pt) * | 1992-12-04 | 2000-12-29 | Janssen Pharmaceutica Nv | Derivados de triazolo(pirrolo tieno ou furano)azepina antialergicos |
| PT1401838E (pt) | 2001-06-12 | 2014-06-09 | Janssen Pharmaceutica Nv | Novos derivados de imidazole tetracíclicos substituidos, processos para a sua preparação, composições farmacêuticas que as compreendem e a sua utilização como um fármaco |
| EP1785424A3 (en) * | 2003-04-11 | 2009-12-23 | High Point Pharmaceuticals, LLC | Fused 1,2,4-triazoles and pharmaceutical uses thereof |
| EP1615647B1 (en) * | 2003-04-11 | 2010-01-20 | High Point Pharmaceuticals, LLC | Pharmaceutical use of fused 1,2,4-triazoles |
| WO2006040329A1 (en) * | 2004-10-12 | 2006-04-20 | Novo Nordisk A/S | 1 ibeta- hydroxysteroid dehydrogenase type 1 active spiro compounds |
| EA200801492A1 (ru) * | 2005-11-01 | 2008-10-30 | Транстек Фарма | Фармацевтическое применение замещенных амидов |
| KR20080076916A (ko) * | 2005-11-01 | 2008-08-20 | 트랜스테크 파르마, 인크. | 치환된 아미드의 약학적 사용 |
| WO2007107550A1 (en) * | 2006-03-21 | 2007-09-27 | High Point Pharmaceuticals, Llc | Adamantane derivatives for the treatment of the metabolic syndrome |
| CA2648074A1 (en) | 2006-04-07 | 2007-10-18 | High Point Pharmaceuticals, Llc | 11.beta.-hydroxysteroid dehydrogenase type 1 active compounds |
| EP1878721A1 (en) * | 2006-07-13 | 2008-01-16 | Novo Nordisk A/S | 4-Piperidylbenzamides as 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors |
| WO2008006702A1 (en) * | 2006-07-13 | 2008-01-17 | High Point Pharmaceuticals, Llc. | 11beta-hydroxysteroid dehydrogenase type 1 active compounds |
| JP2010519240A (ja) * | 2007-02-23 | 2010-06-03 | ハイ ポイント ファーマシューティカルズ，リミティド ライアビリティ カンパニー | １１−ベータ−ヒドロキシステロイドデヒドロゲナーゼの阻害剤としての、ｎ−アダマンチルベンズアミド |
| JP5243455B2 (ja) * | 2007-02-23 | 2013-07-24 | ハイ ポイント ファーマシューティカルズ，リミティド ライアビリティ カンパニー | 新規化合物 |
| WO2008101885A1 (en) * | 2007-02-23 | 2008-08-28 | High Point Pharmaceuticals, Llc | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
| EP2129652A2 (en) * | 2007-02-23 | 2009-12-09 | High Point Pharmaceuticals, LLC | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
| WO2008110196A1 (en) * | 2007-03-09 | 2008-09-18 | High Point Pharmaceuticals, Llc | Indole- and benzimidazole amides as hydroxysteroid dehydrogenase inhibitors |
| US20100056600A1 (en) * | 2007-03-28 | 2010-03-04 | Soren Ebdrup | 11beta-hsd1 active compounds |
| US20100137377A1 (en) * | 2007-04-11 | 2010-06-03 | Soren Ebdrup Et Al | Novel compounds |
| ES2393230T3 (es) * | 2007-04-24 | 2012-12-19 | High Point Pharmaceuticals, Llc | Uso farmacéutico de amidas sustituidas |
| AU2015308350B2 (en) | 2014-08-29 | 2020-03-05 | Tes Pharma S.R.L. | Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH089616B2 (ja) * | 1990-10-10 | 1996-01-31 | シェリング・コーポレーション | 置換されたイミダゾベンズアゼピン類およびイミダゾピリドアゼピン類 |
| IL101850A (en) * | 1991-06-13 | 1996-01-31 | Janssen Pharmaceutica Nv | History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them |
| US5629308A (en) * | 1992-12-04 | 1997-05-13 | Janssen Pharmaceutica N.V. | Imidazo [1,2-A] (pyrrolo, thieno or furano) [2,3-D] azepine derivatives |
| PT675889E (pt) * | 1992-12-04 | 2000-12-29 | Janssen Pharmaceutica Nv | Derivados de triazolo(pirrolo tieno ou furano)azepina antialergicos |
-
1993
- 1993-11-25 PL PL93309253A patent/PL176593B1/pl not_active IP Right Cessation
- 1993-11-25 EP EP94901886A patent/EP0675887B1/en not_active Expired - Lifetime
- 1993-11-25 KR KR1019950702169A patent/KR100251893B1/ko not_active IP Right Cessation
- 1993-11-25 AU AU56278/94A patent/AU676701B2/en not_active Ceased
- 1993-11-25 JP JP51372094A patent/JP3572074B2/ja not_active Expired - Fee Related
- 1993-11-25 ES ES94901886T patent/ES2196020T3/es not_active Expired - Lifetime
- 1993-11-25 AT AT94901886T patent/ATE236164T1/de not_active IP Right Cessation
- 1993-11-25 RU RU95114439A patent/RU2126802C1/ru not_active IP Right Cessation
- 1993-11-25 DE DE69332830T patent/DE69332830T2/de not_active Expired - Fee Related
- 1993-11-25 CA CA002150806A patent/CA2150806C/en not_active Expired - Fee Related
- 1993-11-25 NZ NZ258551A patent/NZ258551A/en unknown
- 1993-11-25 US US08/433,388 patent/US5932569A/en not_active Expired - Fee Related
- 1993-11-25 WO PCT/EP1993/003320 patent/WO1994013671A1/en active IP Right Grant
- 1993-11-25 HU HU9501621A patent/HU223464B1/hu not_active IP Right Cessation
-
1995
- 1995-06-02 NO NO952198A patent/NO305250B1/no unknown
- 1995-06-02 FI FI952722A patent/FI952722A0/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU95114439A (ru) | 1997-06-10 |
| DE69332830T2 (de) | 2004-01-29 |
| NO952198L (no) | 1995-08-03 |
| PL309253A1 (en) | 1995-10-02 |
| JP3572074B2 (ja) | 2004-09-29 |
| RU2126802C1 (ru) | 1999-02-27 |
| FI952722A (fi) | 1995-06-02 |
| AU5627894A (en) | 1994-07-04 |
| US5932569A (en) | 1999-08-03 |
| FI952722A0 (fi) | 1995-06-02 |
| AU676701B2 (en) | 1997-03-20 |
| HUT71811A (en) | 1996-02-28 |
| DE69332830D1 (de) | 2003-05-08 |
| NZ258551A (en) | 1996-06-25 |
| WO1994013671A1 (en) | 1994-06-23 |
| JPH08503952A (ja) | 1996-04-30 |
| ATE236164T1 (de) | 2003-04-15 |
| HU9501621D0 (en) | 1995-08-28 |
| EP0675887B1 (en) | 2003-04-02 |
| HU223464B1 (hu) | 2004-07-28 |
| EP0675887A1 (en) | 1995-10-11 |
| NO952198D0 (no) | 1995-06-02 |
| ES2196020T3 (es) | 2003-12-16 |
| CA2150806A1 (en) | 1994-06-23 |
| KR100251893B1 (ko) | 2000-04-15 |
| CA2150806C (en) | 2006-01-31 |
| PL176593B1 (pl) | 1999-06-30 |
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