NO304651B1 - Trisubstituerte bifenyler, deres anvendelse i legemidler som blodtrykksenke og antiaterosklerotiske midler - Google Patents

Trisubstituerte bifenyler, deres anvendelse i legemidler som blodtrykksenke og antiaterosklerotiske midler

Info

Publication number
NO304651B1
NO304651B1 NO933591A NO933591A NO304651B1 NO 304651 B1 NO304651 B1 NO 304651B1 NO 933591 A NO933591 A NO 933591A NO 933591 A NO933591 A NO 933591A NO 304651 B1 NO304651 B1 NO 304651B1
Authority
NO
Norway
Prior art keywords
drugs
blood pressure
stands
pressure tanks
trisubstituted biphenyls
Prior art date
Application number
NO933591A
Other languages
English (en)
Norwegian (no)
Other versions
NO933591D0 (no
NO933591L (no
Inventor
J Rgen Dressel
Peter Fey
Rudolf Hanko
Bsch Walter H
Thomas Kromer
Ller Ulrich E M
Ller-Gliemann Matthias M
Martin Beuck
Stanislav Kazda
Stefan Wohlfeil
Andreas Knorr
Johannes-Peter Stasch
Siegfried Zaiss
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO933591D0 publication Critical patent/NO933591D0/no
Publication of NO933591L publication Critical patent/NO933591L/no
Publication of NO304651B1 publication Critical patent/NO304651B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO933591A 1992-10-23 1993-10-07 Trisubstituerte bifenyler, deres anvendelse i legemidler som blodtrykksenke og antiaterosklerotiske midler NO304651B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4235933 1992-10-23
DE4319041A DE4319041A1 (de) 1992-10-23 1993-06-08 Trisubstituierte Biphenyle

Publications (3)

Publication Number Publication Date
NO933591D0 NO933591D0 (no) 1993-10-07
NO933591L NO933591L (no) 1994-04-25
NO304651B1 true NO304651B1 (no) 1999-01-25

Family

ID=25919778

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933591A NO304651B1 (no) 1992-10-23 1993-10-07 Trisubstituerte bifenyler, deres anvendelse i legemidler som blodtrykksenke og antiaterosklerotiske midler

Country Status (22)

Country Link
US (2) US5596006A (sk)
EP (1) EP0594019B1 (sk)
JP (1) JPH06199838A (sk)
KR (1) KR100304225B1 (sk)
CN (1) CN1040435C (sk)
AT (1) ATE189893T1 (sk)
AU (1) AU670315B2 (sk)
CA (1) CA2108814A1 (sk)
CZ (1) CZ283482B6 (sk)
DE (2) DE4319041A1 (sk)
DK (1) DK0594019T3 (sk)
ES (1) ES2145021T3 (sk)
FI (1) FI934646A (sk)
GR (1) GR3033207T3 (sk)
HU (1) HUT65819A (sk)
IL (1) IL107333A (sk)
MX (1) MX9306419A (sk)
NO (1) NO304651B1 (sk)
NZ (1) NZ250002A (sk)
PT (1) PT594019E (sk)
SK (1) SK279675B6 (sk)
TW (1) TW248555B (sk)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4319040A1 (de) * 1992-10-23 1994-04-28 Bayer Ag Alkoxymethylsubstituierte Pyridonbiphenyle
WO2002012189A1 (fr) * 2000-08-09 2002-02-14 Mitsubishi Pharma Corporation Composes amide bicycliques condenses et utilisations medicales associees
ES2421511T3 (es) * 2001-12-21 2013-09-03 X Ceptor Therapeutics Inc Moduladores de LXR
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
ES2251292B1 (es) * 2004-04-20 2007-07-01 Inke, S.A. Procedimiento para la obtencion de un compuesto farmaceuticamente activo y de sus intermedios de sintesis.
WO2006130901A1 (en) * 2005-06-07 2006-12-14 Bayer Healthcare Ag Control of metabolic abnormalities
DE102005030522A1 (de) * 2005-06-30 2007-01-04 Bayer Healthcare Ag Salz des Embusartans
TWI448284B (zh) 2007-04-24 2014-08-11 Theravance Inc 雙效抗高血壓劑
DE102007028406A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028319A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028407A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
DE102007028320A1 (de) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituierte Oxazolidinone und ihre Verwendung
EP2138178A1 (en) 2008-06-28 2009-12-30 Bayer Schering Pharma Aktiengesellschaft Oxazolidninones for the treatment fo chronic obstructive pulmonary disease (COPD) and/or asthma
CN104684932B (zh) 2012-05-10 2019-03-12 拜耳药业股份公司 能够结合凝血因子XI和/或其活化形式因子XIa的抗体及其用途
KR102614588B1 (ko) 2018-08-20 2023-12-18 삼성디스플레이 주식회사 표시 장치의 제조 방법
WO2024159724A1 (zh) * 2023-02-03 2024-08-08 科莱博(江苏)科技股份有限公司 一种邻联苯基噁唑啉化合物及其合成方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
CA2018443A1 (en) * 1989-06-14 1990-12-14 Joseph A. Finkelstein Imidazolyl-alkenoic acids
SG52330A1 (en) * 1989-06-14 1998-09-28 Smithkline Beecham Corp Imidazolyl-alkenoic acids
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
EP0485410A1 (en) * 1989-07-06 1992-05-20 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern A detector for monitoring low molecular weight compounds
CA2027937A1 (en) * 1989-10-25 1991-04-26 Richard M. Keenan Substituted 5-¬ (tetrazolyl)alkenyl|imidazoles
EP0460234B1 (en) * 1989-12-25 1997-05-02 Nippon Steel Corporation Sheet of titanium-aluminum intermetallic compound and process for producing the same
GB2244054B (en) * 1990-04-19 1994-04-06 Ici Plc Pyridine derivatives
NZ238624A (en) * 1990-06-19 1994-08-26 Meiji Seika Co Pyridine derivatives, compositions, preparations and use thereof
US5250548A (en) * 1990-09-10 1993-10-05 Abbott Laboratories Angiotensin II receptor antagonists
IL100917A0 (en) * 1991-02-16 1992-11-15 Fisons Plc Pyridinone and pyrimidinone derivatives,their preparation and pharmaceutical compositions containing them
CN1068109A (zh) * 1991-02-16 1993-01-20 菲索斯有限公司 新的血管紧张肽ii拮抗剂及其制剂的制备和应用
DE4221583A1 (de) * 1991-11-12 1993-05-13 Bayer Ag Substituierte biphenylpyridone
US5206374A (en) * 1991-11-18 1993-04-27 E. I. Du Pont De Nemours And Company Process for preparing tetrazolylphenylboronic acid intermediates
US5130439A (en) * 1991-11-18 1992-07-14 Lo Young S Tetrazolylphenylboronic acid intermediates for the synthesis of AII receptor antagonists
DE69233734D1 (de) * 1991-11-18 2008-06-26 Du Pont 2-(2'-Triphenylmethyl-2'H-tetrazol-5'-yl)phenylborsäure als Zwischenprodukt zur Synthese von A II Receptorenantagonisten
US5310928A (en) * 1991-11-18 1994-05-10 E. I. Du Pont De Nemours And Company Process for preparing biphenyltetrazole compounds
DE4319040A1 (de) * 1992-10-23 1994-04-28 Bayer Ag Alkoxymethylsubstituierte Pyridonbiphenyle

Also Published As

Publication number Publication date
HU9302997D0 (en) 1994-01-28
DE4319041A1 (de) 1994-04-28
IL107333A (en) 1998-01-04
ES2145021T3 (es) 2000-07-01
FI934646A0 (fi) 1993-10-21
NZ250002A (en) 1995-03-28
EP0594019A1 (de) 1994-04-27
KR940009174A (ko) 1994-05-20
CN1040435C (zh) 1998-10-28
SK279675B6 (sk) 1999-02-11
US5596006A (en) 1997-01-21
KR100304225B1 (ko) 2004-05-10
FI934646A (fi) 1994-04-24
HUT65819A (en) 1994-07-28
MX9306419A (es) 1994-05-31
EP0594019B1 (de) 2000-02-23
NO933591D0 (no) 1993-10-07
DE59309956D1 (de) 2000-03-30
CN1089260A (zh) 1994-07-13
AU4754193A (en) 1994-05-05
NO933591L (no) 1994-04-25
JPH06199838A (ja) 1994-07-19
IL107333A0 (en) 1994-01-25
DK0594019T3 (da) 2000-07-03
US5863930A (en) 1999-01-26
CZ221793A3 (en) 1994-05-18
ATE189893T1 (de) 2000-03-15
CA2108814A1 (en) 1994-04-24
SK116993A3 (en) 1994-11-09
PT594019E (pt) 2000-08-31
GR3033207T3 (en) 2000-08-31
AU670315B2 (en) 1996-07-11
TW248555B (sk) 1995-06-01
CZ283482B6 (cs) 1998-04-15

Similar Documents

Publication Publication Date Title
NO304651B1 (no) Trisubstituerte bifenyler, deres anvendelse i legemidler som blodtrykksenke og antiaterosklerotiske midler
HU9600572D0 (en) Medicament for inhibiting gastric acid secretion, multiple unit tablated dosage form
PE20010400A1 (es) Formulacion de sal comun y moxifloxacina
DE59400489D1 (de) Fungizide Wirkstoffkombinationen
ATE283051T1 (de) Synergistisch,analgetische zusammensetzung mit opiod-analgetika und zyklooxygenase-2 inhibitoren
DK0611767T3 (da) Heterocyclisk substituerede phenylcyclohexancarboxylsyrederivater som angiotension II-antagonister
DK0542059T3 (da) Substituerede biphenylpyridoner som angiotensin II-antagonister
CO4520286A1 (es) Procedimiento para preparar clorhidrato de 1-(2 -desoxi-2 , 2 -difluoro-d-ribofuranosil)-4-aminopirimidin-2-ona
CL2008003324A1 (es) Formulacion farmaceutica liquida de liberacion inmediata que comprende una sal de adicion de acido de un compuesto derivado de azetidina sustituido y un diluyente o portador farmaceuticamente aceptable, util para el tratamiento o prevencion de trombosis.
KR960013371A (ko) 약학적 혼합물
ITMI931326A1 (it) Composizione farmaceutica liquida per uso orale contenente acido 2-(4-isobutilfenil) propionico
ATE157080T1 (de) Ethanolaminderivate mit anti-pollakiurawirkung
BR9910201A (pt) Sistema terapêutico transdérmico para emprego de candesartan
PA8483301A1 (es) Concentrado oral de sertralina
EP0466944A4 (en) 4h-3,1-benzoxazin-4-one compound and elastase inhibitor composition containing the same
ES2156877T3 (es) Anilidas de acidos cicloalquilcarboxilicos.
NO305799B1 (no) Nye kinolinderivater, farmas°ytiske preparater inneholdende slike derivater, deres anvendelse samt mellomprodukter
GB2381455A (en) Treatment of burns
WO2001041771A3 (de) Acetylsalicylsäure enthaltendes transdermales system zur behandlung von migräne
FR2700116B1 (fr) Application d'anticonvulsivants comme radioprotecteurs.
NO303640B1 (no) Ny forbindelse, Leustroducsin H, farmas°ytisk preparat som omfatter den, og dens anvendelse til fremstilling av et slikt preparat
ITMI921181A1 (it) 2-(sostituite immino)-tiazolidine e procedimento per la loro preparazione e loro impiego quali antianginose e/o analgesiche

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN APRIL 2002