NO304113B1 - Krystallinsk tiagabinhydrokloridmonohydrat, farmas°ytisk preparat som omfatter det, og anvendelse derav for fremstilling av et medikament - Google Patents

Krystallinsk tiagabinhydrokloridmonohydrat, farmas°ytisk preparat som omfatter det, og anvendelse derav for fremstilling av et medikament

Info

Publication number
NO304113B1
NO304113B1 NO933524A NO933524A NO304113B1 NO 304113 B1 NO304113 B1 NO 304113B1 NO 933524 A NO933524 A NO 933524A NO 933524 A NO933524 A NO 933524A NO 304113 B1 NO304113 B1 NO 304113B1
Authority
NO
Norway
Prior art keywords
medicament
crystalline
manufacture
pharmaceutical composition
hydrochloride monohydrate
Prior art date
Application number
NO933524A
Other languages
English (en)
Norwegian (no)
Other versions
NO933524D0 (no
NO933524L (no
Inventor
Henning Petersen
Peter Nielsen
Michael Cain
Subhash R Patel
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO933524D0 publication Critical patent/NO933524D0/no
Publication of NO933524L publication Critical patent/NO933524L/no
Publication of NO304113B1 publication Critical patent/NO304113B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Transceivers (AREA)
  • Mobile Radio Communication Systems (AREA)
NO933524A 1991-04-02 1993-10-01 Krystallinsk tiagabinhydrokloridmonohydrat, farmas°ytisk preparat som omfatter det, og anvendelse derav for fremstilling av et medikament NO304113B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK91582A DK58291D0 (da) 1991-04-02 1991-04-02 Krystalinsk stof og dets fremstilling
PCT/DK1992/000093 WO1992017473A1 (en) 1991-04-02 1992-03-23 Crystalline tiagabine hydrochloride monohydrate, its preparation and use

Publications (3)

Publication Number Publication Date
NO933524D0 NO933524D0 (no) 1993-10-01
NO933524L NO933524L (no) 1993-10-01
NO304113B1 true NO304113B1 (no) 1998-10-26

Family

ID=8095193

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933524A NO304113B1 (no) 1991-04-02 1993-10-01 Krystallinsk tiagabinhydrokloridmonohydrat, farmas°ytisk preparat som omfatter det, og anvendelse derav for fremstilling av et medikament

Country Status (15)

Country Link
US (1) US5354760A (da)
EP (1) EP0579681B1 (da)
AT (1) ATE180781T1 (da)
AU (1) AU661483B2 (da)
CA (1) CA2107223C (da)
DE (1) DE69229339T2 (da)
DK (2) DK58291D0 (da)
ES (1) ES2134801T3 (da)
FI (1) FI110096B (da)
GR (1) GR3030919T3 (da)
IL (1) IL101358A (da)
NO (1) NO304113B1 (da)
NZ (1) NZ242191A (da)
WO (1) WO1992017473A1 (da)
ZA (1) ZA922297B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750140A (en) * 1994-05-20 1998-05-12 Novo Nordisk A/S Transdermal delivery of tiagabine
NZ307159A (en) * 1995-05-05 1998-10-28 Novo Nordisk As Medicament containing tiagabine, antioxidant, and carrier
AU736514B2 (en) * 1995-07-13 2001-07-26 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Non-allosteric gabaa agonists for treating sleep disorders
DE19525598C2 (de) * 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel
UA52661C2 (uk) * 1996-06-14 2003-01-15 Ново Нордіск А/С Безводна кристалічна форма гідрохлориду r(-)-n-(4,4-ди(3-метилтієн-2-іл)бут-3-еніл) ніпекотинової кислоти
US5914333A (en) * 1996-07-31 1999-06-22 Novo Nordisk A/S Treatment of psychotic disorders
IE970588A1 (en) 1997-08-01 2000-08-23 Elan Corp Plc Controlled release pharmaceutical compositions containing tiagabine
FR2771292B1 (fr) * 1997-11-21 2000-02-18 Ethypharm Lab Prod Ethiques Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques
US6410520B2 (en) 2000-02-01 2002-06-25 The Procter & Gamble Company Selective crystallization of 3-pyridyl-1-hydroxyethylidene-1, 1-bisphosphonic acid sodium as the hemipentahydrate or monohydrate
US6562974B2 (en) 2000-02-01 2003-05-13 The Procter & Gamble Company Process for making geminal bisphosphonates
EP1490090A4 (en) 2002-02-22 2006-09-20 New River Pharmaceuticals Inc SYSTEMS FOR DELIVERING ACTIVE AGENTS AND METHODS FOR PROTECTING AND DELIVERING ACTIVE AGENTS
WO2005122698A2 (en) * 2003-12-24 2005-12-29 Sun Pharmaceutical Industries Limited Novel stable polymorphic forms of tiagabine hydrochloride
CN1314684C (zh) * 2003-12-24 2007-05-09 中国科学院上海有机化学研究所 噻加宾及其消旋体和s-构型的合成方法及其无定形粉末的制法
WO2005092886A1 (en) * 2004-03-29 2005-10-06 Ranbaxy Laboratories Limited Process for the preparation of amorphous form of tiagabine
US20080269495A1 (en) * 2004-08-04 2008-10-30 Prosenjit Bose Process for Preparation of Piperidine Carboxylic Acid
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US20080051435A1 (en) * 2006-08-18 2008-02-28 Cephalon, Inc. Crystalline and amorphous forms of tiagabine
US20080064727A1 (en) * 2006-08-18 2008-03-13 Cephalon, Inc. Crystalline forms of tiagabine hydrochloride
CN101857591B (zh) * 2009-04-09 2013-06-05 北京京卫燕康药物研究所有限公司 盐酸噻加宾晶型及其制备方法
CN103554093B (zh) * 2013-11-12 2015-10-21 四川科瑞德凯华制药有限公司 噻加宾乙酯盐酸盐及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK288385D0 (da) * 1985-06-26 1985-06-26 Novo Industri As Aminosyrederivater
DE3688827T2 (de) * 1985-10-25 1994-03-31 Beecham Group Plc Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel.
US4910312A (en) * 1985-11-08 1990-03-20 Warner-Lambert Company Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof

Also Published As

Publication number Publication date
DE69229339D1 (de) 1999-07-08
FI934298A0 (fi) 1993-09-30
CA2107223C (en) 2005-02-15
DK0579681T3 (da) 1999-11-15
DK58291D0 (da) 1991-04-02
ES2134801T3 (es) 1999-10-16
ZA922297B (en) 1992-12-30
WO1992017473A1 (en) 1992-10-15
JPH06506209A (ja) 1994-07-14
NO933524D0 (no) 1993-10-01
GR3030919T3 (en) 1999-11-30
EP0579681A1 (en) 1994-01-26
NZ242191A (en) 1994-07-26
IL101358A0 (en) 1992-11-15
ATE180781T1 (de) 1999-06-15
NO933524L (no) 1993-10-01
IL101358A (en) 1996-08-04
US5354760A (en) 1994-10-11
DE69229339T2 (de) 1999-12-30
EP0579681B1 (en) 1999-06-02
FI110096B (fi) 2002-11-29
AU1641592A (en) 1992-11-02
FI934298A (fi) 1993-09-30
AU661483B2 (en) 1995-07-27
CA2107223A1 (en) 1992-10-03

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