NO303578B1 - Anvendelse av 2,3-trans-disubstituerte tropanforbindelser for fremstilling av medikamenter, samt slike forbindelser og farmas°ytiske preparater som omfatter dem - Google Patents

Anvendelse av 2,3-trans-disubstituerte tropanforbindelser for fremstilling av medikamenter, samt slike forbindelser og farmas°ytiske preparater som omfatter dem

Info

Publication number
NO303578B1
NO303578B1 NO934761A NO934761A NO303578B1 NO 303578 B1 NO303578 B1 NO 303578B1 NO 934761 A NO934761 A NO 934761A NO 934761 A NO934761 A NO 934761A NO 303578 B1 NO303578 B1 NO 303578B1
Authority
NO
Norway
Prior art keywords
compounds
medicaments
trans
manufacture
well
Prior art date
Application number
NO934761A
Other languages
English (en)
Other versions
NO934761D0 (no
NO934761L (no
Inventor
Peter Moldt
Jorgen Scheel-Krueger
Leif Helth Jensen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK921541A external-priority patent/DK154192D0/da
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of NO934761D0 publication Critical patent/NO934761D0/no
Publication of NO934761L publication Critical patent/NO934761L/no
Publication of NO303578B1 publication Critical patent/NO303578B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Hydrogenated Pyridines (AREA)
NO934761A 1992-12-23 1993-12-22 Anvendelse av 2,3-trans-disubstituerte tropanforbindelser for fremstilling av medikamenter, samt slike forbindelser og farmas°ytiske preparater som omfatter dem NO303578B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK921541A DK154192D0 (da) 1992-12-23 1992-12-23 Heterocycliske forbindelser
US08/093,182 US5374636A (en) 1992-12-23 1993-07-16 2,3-trans-disubstituted tropane compounds which have useful pharmaceutical utility

Publications (3)

Publication Number Publication Date
NO934761D0 NO934761D0 (no) 1993-12-22
NO934761L NO934761L (no) 1994-06-24
NO303578B1 true NO303578B1 (no) 1998-08-03

Family

ID=26065882

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934761A NO303578B1 (no) 1992-12-23 1993-12-22 Anvendelse av 2,3-trans-disubstituerte tropanforbindelser for fremstilling av medikamenter, samt slike forbindelser og farmas°ytiske preparater som omfatter dem

Country Status (9)

Country Link
EP (1) EP0604354B1 (no)
JP (1) JP3841449B2 (no)
AT (1) ATE231147T1 (no)
AU (1) AU672052B2 (no)
CA (1) CA2112084C (no)
DE (1) DE69332636T2 (no)
FI (1) FI935800A (no)
NO (1) NO303578B1 (no)
NZ (1) NZ250515A (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026274A1 (en) * 1993-05-18 1994-11-24 Wake Forest University Treatment process with biologically active tropane derivatives
HU215830B (hu) * 1994-04-19 2001-05-28 Neurosearch A/S Tropán-2-aldoxim-származékok, e vegyületeket tartalmazó gyógyászati készítmények, valamint e vegyületek előállítása és alkalmazása gyógyszerkészítmények előállítására
TR199800628T2 (xx) * 1995-10-13 1998-07-21 Neurosearch A/S 8-Azabisiklo$3.2.1]okt-2-en t�revleri, bunlar�n haz�rlanmas� ve kullan�m�.
UA49872C2 (uk) * 1996-02-22 2002-10-15 Н'Юросерч А/С Похідні тропану, спосіб їх одержання, фармацевтична композиція та спосіб лікування
WO1999038866A1 (en) * 1998-01-28 1999-08-05 Neurosearch A/S 8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled form and use of 8-azabicyclo[3.2.1]oct-2-ene derivatives in labelled and unlabelled form
AU4819099A (en) * 1998-06-19 2000-01-05 Eli Lilly And Company Inhibition of serotonin reuptake
CA2396956C (en) * 2000-01-11 2010-10-26 Biostream Therapeutics, Inc. Polypharmacophoric agents
JP2005500371A (ja) * 2001-08-08 2005-01-06 ニューロサーチ、アクティーゼルスカブ 置換されたアミン誘導体及びこれをモノアミン神経伝達物質再取り込み阻害剤として使用する方法
CA2458801A1 (en) 2001-08-17 2003-02-27 President And Fellows Of Harvard College Therapeutic tropane compounds
JP2005511639A (ja) 2001-11-30 2005-04-28 ニューロサーチ、アクティーゼルスカブ 虚血性疾患の治療用ドパミン再取り込み阻害活性を有するトロパン誘導体
EP1594868B1 (en) * 2003-02-12 2009-11-11 Neurosearch A/S 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
CN100551924C (zh) * 2003-02-12 2009-10-21 神经研究公司 8-氮杂-双环[3.2.1]辛烷衍生物和它们作为单胺神经递质再摄取抑制剂的用途
EP1594874A1 (en) 2003-02-12 2005-11-16 Neurosearch A/S Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
MXPA06003762A (es) 2003-10-16 2006-06-14 Boehringer Ingelheim Int Composicion farmaceutica que comprende un inhibidor de recaptacion de neurotransmisor monoamina y un inhibidor de acetilcolinesterasa.
WO2007028770A1 (en) * 2005-09-05 2007-03-15 Neurosearch A/S Monoamine neurotransmitter re-uptake inhibitors for neuroprotection in patients suffering from an advanced stage of a mental disease
EP1779851A1 (en) 2005-10-31 2007-05-02 Boehringer Ingelheim Pharma GmbH & Co.KG Treatment of diabetes

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3813404A (en) * 1972-11-15 1974-05-28 Sterling Drug Inc Tropane-2-carboxylates and derivatives
US3901892A (en) * 1973-12-14 1975-08-26 Sterling Drug Inc 1,3-ethanoindeno(2,1-c)-pyridines and 1,3-ethanobenz(g)isoquinolines
FR2276823A1 (fr) * 1974-07-04 1976-01-30 Roussel Uclaf Nouveaux derives de la dibenzo(b.e)thiepine et leurs sels, procede de preparation et application a titre de medicaments desdits produits
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
IL88156A (en) * 1987-11-13 1997-02-18 Novo Nordisk As Azacyclic compounds their preparation and pharmaceutical compositions containing them
NZ227684A (en) * 1988-01-30 1991-07-26 Merck Sharp & Dohme Pyrazine, pyridazine, and pyrimidine derivatives and pharmaceutical compositions
EP0398578B1 (en) * 1989-05-17 1997-03-12 Pfizer Inc. 2-piperidino-1-alkanol derivatives as antiischemic agents
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
DE69233656D1 (de) * 1991-11-15 2006-10-19 Res Triangle Inst Kokain-Rezeptor Bindungsliganden
US5262428A (en) * 1992-03-13 1993-11-16 Wake Forest University Biologically active tropane derivatives
US5268480A (en) * 1992-09-22 1993-12-07 Mayo Foundation For Medical Education And Research Cocaine analogs

Also Published As

Publication number Publication date
ATE231147T1 (de) 2003-02-15
NO934761D0 (no) 1993-12-22
FI935800A0 (fi) 1993-12-22
FI935800A (fi) 1994-06-24
JP3841449B2 (ja) 2006-11-01
EP0604354A3 (en) 1995-02-08
EP0604354B1 (en) 2003-01-15
AU672052B2 (en) 1996-09-19
NZ250515A (en) 1996-09-25
CA2112084A1 (en) 1994-06-24
CA2112084C (en) 2002-06-11
DE69332636T2 (de) 2003-09-11
EP0604354A2 (en) 1994-06-29
JPH06293758A (ja) 1994-10-21
NO934761L (no) 1994-06-24
AU5236293A (en) 1994-07-07
DE69332636D1 (de) 2003-02-20

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