NO303287B1 - DNA, DNA-fragment, rekombinant DNA, DNA-hybridisasjonsprobe, vertscelle, rekombinant peptid og immunogen sammensetning - Google Patents

DNA, DNA-fragment, rekombinant DNA, DNA-hybridisasjonsprobe, vertscelle, rekombinant peptid og immunogen sammensetning Download PDF

Info

Publication number
NO303287B1
NO303287B1 NO874750A NO874750A NO303287B1 NO 303287 B1 NO303287 B1 NO 303287B1 NO 874750 A NO874750 A NO 874750A NO 874750 A NO874750 A NO 874750A NO 303287 B1 NO303287 B1 NO 303287B1
Authority
NO
Norway
Prior art keywords
dna
hpv
nucleotide
fragment
recombinant
Prior art date
Application number
NO874750A
Other languages
English (en)
Norwegian (no)
Other versions
NO874750D0 (no
NO874750L (no
Inventor
Rolf E Streeck
Stewart Cole
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut filed Critical Pasteur Institut
Publication of NO874750D0 publication Critical patent/NO874750D0/no
Publication of NO874750L publication Critical patent/NO874750L/no
Publication of NO303287B1 publication Critical patent/NO303287B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/708Specific hybridization probes for papilloma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NO874750A 1986-03-21 1987-11-13 DNA, DNA-fragment, rekombinant DNA, DNA-hybridisasjonsprobe, vertscelle, rekombinant peptid og immunogen sammensetning NO303287B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP86400609 1986-03-21
PCT/EP1987/000158 WO1987005630A1 (fr) 1986-03-21 1987-03-20 Sequences d'adn determinees derivees d'un genome du virus du papillome, utilisation desdites sequences pour des diagnostiques in vitro et production de compositions antigenes

Publications (3)

Publication Number Publication Date
NO874750D0 NO874750D0 (no) 1987-11-13
NO874750L NO874750L (no) 1987-11-13
NO303287B1 true NO303287B1 (no) 1998-06-22

Family

ID=8196291

Family Applications (1)

Application Number Title Priority Date Filing Date
NO874750A NO303287B1 (no) 1986-03-21 1987-11-13 DNA, DNA-fragment, rekombinant DNA, DNA-hybridisasjonsprobe, vertscelle, rekombinant peptid og immunogen sammensetning

Country Status (13)

Country Link
US (7) US5554538A (fr)
EP (1) EP0243221B1 (fr)
JP (2) JP2633275B2 (fr)
KR (1) KR930007580B1 (fr)
AT (1) ATE76429T1 (fr)
AU (1) AU615159B2 (fr)
DE (1) DE3779175D1 (fr)
DK (1) DK175314B1 (fr)
ES (1) ES2039254T3 (fr)
FI (1) FI100057B (fr)
GR (1) GR3005272T3 (fr)
NO (1) NO303287B1 (fr)
WO (1) WO1987005630A1 (fr)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876922A (en) 1985-07-31 1999-03-02 Institute Pasteur Papillomavirus probe and a process for in vitro diagnosis of papillomavirus infections
KR930007580B1 (ko) * 1986-03-21 1993-08-13 엥스띠뛰 빠스뙤르 유두종 비루스 게놈으로부터 유도된 결정 dna 서열, 그의 시험관내 진단 목적용 용도 및 항원 조성물의 제조 방법
US4777239A (en) * 1986-07-10 1988-10-11 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic peptides of human papilloma virus
FR2629458B2 (fr) * 1987-07-31 1991-08-09 Ire Celltarg Sa Nouvelles sondes d'acides nucleiques specifiques de differents types de virus de papillome humain
JPH03503605A (ja) * 1988-04-04 1991-08-15 オンカー インコーポレーテッド ヒトパピローマウイルス分類法および該方法に使用する核酸プローブ
FR2632956B2 (fr) * 1988-05-13 1991-07-12 Pasteur Institut Sondes a papillomavirus hpv49, hpv50, hpv54, hpv55; produits genetiquement et immunologiquement lies a ce papillomavirus hpv49, hpv50, hpv54, hpv55; procede de diagnostic in vitro d'infections a papillomavirus et d'immunisation in vivo contre ces papillomavirus
FR2631341B1 (fr) * 1988-05-13 1991-04-26 Pasteur Institut Sondes a papillomavirus hpv49, hpv50, hpv54, hpv55 et produits genetiquement et immunologiquement lies a ce papillomavirus hpv49, hpv50, hpv54, hpv55 et procede de diagnostic in vitro d'infections a papillomavirus et d'immunisation in vivo contre ces papillomavirus
CA1339729C (fr) * 1988-10-26 1998-03-17 Wayne D. Lancaster Sequences d'and pour virus des papillomes humains de type 52 methode d'utilisation
SE8803870D0 (sv) * 1988-10-28 1988-10-28 Medscand Ab Method for detection of human papillomavirus (hpv) for diagnostic purposes
DE3838269A1 (de) * 1988-11-11 1990-05-17 Behringwerke Ag Nachweis humaner papillomavirus dna und ihrer expression in zervix-abstrichen
JPH05501650A (ja) * 1989-12-01 1993-04-02 バイシス・インコーポレーテツド Hpv転写物の検出
US5580970A (en) * 1989-12-01 1996-12-03 Amoco Corporation Detection of HPV transcripts
FR2656627B1 (fr) * 1989-12-28 1992-04-17 Pasteur Institut Sonde a papillomavirus (hvpv63), notamment pour le diagnostic in vitro d'infections a papillomavirus, pouvant s'accompagner de neoplasies genitales, et produits genetiquement et immunologiquement lies a ce papillomavirus.
SE9001705D0 (sv) * 1990-05-11 1990-05-11 Medscand Ab Saett foer diagnostik av virusbaerande tumoerer genom immunoassay
US5932412A (en) * 1990-05-11 1999-08-03 Euro-Diagnostica Ab Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes
CA2052413C (fr) * 1990-09-28 2004-07-13 Jeffrey L. Joseph Sequence de nucleotides utiles comme sondes specifiques, amorces de la rcp et sondes de la rcl pour l'amplification et la detection du virus du papillome humain, et trousses et methodes connexes
US6013258A (en) * 1997-10-09 2000-01-11 Zycos Inc. Immunogenic peptides from the HPV E7 protein
US6183746B1 (en) * 1997-10-09 2001-02-06 Zycos Inc. Immunogenic peptides from the HPV E7 protein
US7569344B2 (en) * 1998-10-26 2009-08-04 Ventana Medical Systems, Inc. Detection of human papilloma virus in papanicolaou (Pap) smears
WO2000061804A1 (fr) * 1999-04-14 2000-10-19 Musc Foundation For Research Development Agents toxiques et ribozymes specifiques de tissu et specifiques de pathogene
US20050100928A1 (en) * 1999-09-16 2005-05-12 Zycos Inc., A Delaware Corporation Nucleic acids encoding polyepitope polypeptides
US20060275784A1 (en) * 1999-10-26 2006-12-07 Ventana Medical Systems, Inc. Detection of Human Papilloma Virus in Papanicolaou (Pap) Smears
AU2001256976A1 (en) * 2000-04-03 2001-10-15 Cytyc Corporation Detection and typing of human papillomavirus using pna probes
US6936443B2 (en) * 2000-04-03 2005-08-30 Cytyc Corporation Detection and typing of human papillomavirus using PNA probes
US20040229298A1 (en) * 2000-11-11 2004-11-18 Lu Peter S. Methods and compositions for treating cervical cancer
US7312041B2 (en) * 2001-02-16 2007-12-25 Arbor Vita Corporation Methods of diagnosing cervical cancer
US20030059806A1 (en) * 2001-01-05 2003-03-27 Science & Technology Corporation @ Unm Probes for the detection of human papillomavirus
NZ533703A (en) 2002-01-07 2006-05-26 Norchip As Method for detecting human papillomavirus mRNA
HUP0200981A3 (en) 2002-03-14 2004-06-28 Genoid Kft Pcr reactions with hybridizing probes using primers with broad genotype-specificity for detection of human papilloma-viruses and typing amplificates by using specifically hybridizing oligonucleotides
JP2005537028A (ja) * 2002-06-26 2005-12-08 ザ ペン ステート リサーチ ファウンデーション ヒト乳頭腫ウイルス感染症を治療する方法及び材料
EP1537415B1 (fr) 2002-09-09 2008-12-17 Arbor Vita Corporation Procede de diagnostic du cancer du col de l'uterus
US20060247190A1 (en) * 2002-10-21 2006-11-02 Kathleen Beach Compositions and methods for treating human papillomavirus mediated disease
EP1664348B8 (fr) 2003-09-25 2019-06-12 Third Wave Technologies, Inc. Detection de papillomavirus
AU2004308964B2 (en) * 2003-12-23 2010-09-16 Arbor Vita Corporation Antibodies for oncogenic strains of HPV and methods of their use
ATE476528T1 (de) 2004-12-08 2010-08-15 Gen Probe Inc Nukleinsäuredetektion aus verschiedenen typen des humanen papillomavirus
NZ554229A (en) * 2004-12-10 2009-03-31 Genera Biosystems Pty Ltd Human papilloma virus (HPV) detection using nucleic acid probes, microbeads and fluorescent-activated cell sorter (FACS)
JP5224821B2 (ja) 2005-02-01 2013-07-03 アメリカ合衆国 広範に交差中和する抗体を誘導するためのパピローマウイルスl2n末端ペプチド
US20070031826A1 (en) * 2005-08-05 2007-02-08 My Gene Diagnostic kit for determining the genotype of a human papilloma virus and method of using thereof
US7972776B2 (en) * 2005-11-15 2011-07-05 Oncohealth Corporation Protein chips for HPV detection
US7732166B2 (en) * 2005-11-15 2010-06-08 Oncohealth Corporation Detection method for human pappilomavirus (HPV) and its application in cervical cancer
US8080643B2 (en) * 2006-09-05 2011-12-20 Third Wave Technologies, Inc. HPV primers
US20100003704A1 (en) * 2008-06-13 2010-01-07 Shuling Cheng IN SITU detection of early stages and late stages HPV infection
WO2010129821A1 (fr) 2009-05-07 2010-11-11 Oncohealth Corporation Identification de grade élevée ou ≥cin2 pour détection, surveillance et diagnostic, à des stades précoces et des stades avancés, de papillomavirus humain (hpv) et de cancers associés au hpv
US8968995B2 (en) * 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
WO2008124091A2 (fr) * 2007-04-05 2008-10-16 Genera Biosystems Limited Compositions et procédés de détection
US8980562B1 (en) 2007-06-12 2015-03-17 Physicians Reference Laboratory Method of simultaneous detection and typing of human papilloma viruses
WO2011084598A1 (fr) 2010-01-08 2011-07-14 Oncohealth Corporation Immunoessais sur le vph à base de cellule et à haut débit pour diagnostiquer et dépister des cancers associés au vph
BR112012018545A2 (pt) 2010-01-29 2016-05-03 Qiagen Gaithersburg Inc método de determinação e confirmação da presença de um hpv em uma amostra
AU2011258501B2 (en) 2010-05-25 2016-07-07 Qiagen Gaithersburg, Inc. Fast results hybrid capture assay and associated strategically-truncated probes
CN102229660B (zh) * 2011-05-25 2015-04-22 厦门大学 截短的人乳头瘤病毒33型l1蛋白
CN104076150A (zh) * 2013-03-28 2014-10-01 沈萍萍 一种hpv-e6蛋白的检测方法
US9936943B1 (en) 2014-08-07 2018-04-10 Nicholas MANCINI Suture passing surgical device with atraumatic grasper preventing accidental perforations

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
US4419446A (en) * 1980-12-31 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Recombinant DNA process utilizing a papilloma virus DNA as a vector
FR2524487B1 (fr) * 1982-04-05 1985-11-22 Pasteur Institut Fragments d'adn codant pour des polypeptides contenant au moins un determinant antigenique des papillomavirus, notamment du type hpv 1a et polypeptides correspondants
US4748109A (en) * 1983-07-01 1988-05-31 Baird Phillip J Assay method and reagent to determine antibodies to papillomavirus virions
US5411857A (en) * 1985-07-31 1995-05-02 Institut Nationale De La Sante Probes for papillomaviruses and an in vitro diagnostic procedure for papilloma infections
CA1276575C (fr) * 1984-11-30 1990-11-20 Sylvie Beaudenon Sondes a papillomavirus et procede de diagnostic in vitro d'infections a papillomavirus
WO1986005816A1 (fr) * 1985-04-04 1986-10-09 Georgetown University Sequences adn et peptides specifiques au virus du papillome
FR2586428B1 (fr) * 1985-08-26 1988-11-25 Pasteur Institut Polypeptides et anticorps, caracteristiques du papillomavirus et leurs applications au diagnostic in vitro, a la prevention et/ou la lutte contre des infections a papillomavirus
KR930007580B1 (ko) * 1986-03-21 1993-08-13 엥스띠뛰 빠스뙤르 유두종 비루스 게놈으로부터 유도된 결정 dna 서열, 그의 시험관내 진단 목적용 용도 및 항원 조성물의 제조 방법
US4849322A (en) * 1986-04-30 1989-07-18 E. I. Du Pont De Nemours And Company Positive-working color proofing film and process
DE3625257A1 (de) * 1986-07-23 1988-02-04 Behringwerke Ag Expressionsprodukte der menschlichen papillomviren typ 16 und 18, fuer diese proteine spezifische antikoerper und diese antikoerper bzw. entsprechende dna enthaltende diagnostika
US4849332A (en) * 1987-05-26 1989-07-18 Life Technologies, Inc. Human papillomavirus 35 nucleic acid hybridization probes and methods for employing the same
US4849331A (en) * 1987-06-09 1989-07-18 Life Technologies, Inc. Human papillomavirus 44 nucleic acid hybridization probes and methods for employing the same
US4849334A (en) * 1987-06-09 1989-07-18 Life Technologies, Inc. Human papillomavirus 43 nucleic acid hybridization probes and methods for employing the same
DE3722967A1 (de) * 1987-07-11 1989-01-19 Behringwerke Ag Monoklonale antikoerper gegen e7-protein des humanen papillomvirus typ 16, verfahren zu ihrer herstellung sowie ihre verwendung
FR2629458B2 (fr) * 1987-07-31 1991-08-09 Ire Celltarg Sa Nouvelles sondes d'acides nucleiques specifiques de differents types de virus de papillome humain
US5182377A (en) * 1988-09-09 1993-01-26 Hoffmann-La Roche Inc. Probes for detection of human papillomavirus
DE3935592A1 (de) * 1989-10-26 1991-05-02 Hella Kg Hueck & Co Verfahren und einrichtung zur regelung der innenraumtemperatur von kraftfahrzeugen
JPH05501650A (ja) * 1989-12-01 1993-04-02 バイシス・インコーポレーテツド Hpv転写物の検出
FR2663040B1 (fr) * 1990-06-11 1995-09-15 Bio Merieux Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich.
CA2052413C (fr) * 1990-09-28 2004-07-13 Jeffrey L. Joseph Sequence de nucleotides utiles comme sondes specifiques, amorces de la rcp et sondes de la rcl pour l'amplification et la detection du virus du papillome humain, et trousses et methodes connexes
IT1244462B (it) * 1990-12-06 1994-07-15 Sclavo Spa Oligonucleotidi sintetici utili per la diagnosi di infezione da tipi diversi di virus del gruppo papilloma e loro utilizzazione

Also Published As

Publication number Publication date
JP2735537B2 (ja) 1998-04-02
ATE76429T1 (de) 1992-06-15
FI875082A0 (fi) 1987-11-17
US5876723A (en) 1999-03-02
DK605987A (da) 1987-11-18
DE3779175D1 (de) 1992-06-25
FI875082A (fi) 1987-11-17
JPS63502798A (ja) 1988-10-20
US6344314B2 (en) 2002-02-05
US7063963B2 (en) 2006-06-20
US6107086A (en) 2000-08-22
GR3005272T3 (fr) 1993-05-24
DK175314B1 (da) 2004-08-16
NO874750D0 (no) 1987-11-13
ES2039254T3 (es) 1995-04-01
US20040132012A1 (en) 2004-07-08
DK605987D0 (da) 1987-11-18
NO874750L (no) 1987-11-13
FI100057B (fi) 1997-09-15
EP0243221A1 (fr) 1987-10-28
US6242250B1 (en) 2001-06-05
WO1987005630A1 (fr) 1987-09-24
US5554538A (en) 1996-09-10
US5648459A (en) 1997-07-15
AU7200787A (en) 1987-10-09
JP2633275B2 (ja) 1997-07-23
US20010049137A1 (en) 2001-12-06
KR930007580B1 (ko) 1993-08-13
JPH09117294A (ja) 1997-05-06
AU615159B2 (en) 1991-09-26
EP0243221B1 (fr) 1992-05-20

Similar Documents

Publication Publication Date Title
NO303287B1 (no) DNA, DNA-fragment, rekombinant DNA, DNA-hybridisasjonsprobe, vertscelle, rekombinant peptid og immunogen sammensetning
Cole et al. Genome organization and nucleotide sequence of human papillomavirus type 33, which is associated with cervical cancer
Seif et al. The genome of human papovavirus BKV
JP4912885B2 (ja) 酵母におけるhpv58l1の最適化発現
Zhou et al. Interaction of human papillomavirus (HPV) type 16 capsid proteins with HPV DNA requires an intact L2 N-terminal sequence
KR101165278B1 (ko) 효모에서의 hpv 45 l1의 최적화된 발현
JP3207389B2 (ja) 乳頭腫ウィルス及びその診断方法
Loeber et al. Temperature-sensitive mutants identify crucial structural regions of simian virus 40 large T antigen
EP1140974B1 (fr) Dosage neutralisant utilisant des particules veriformes du papillomavirus humain
Bollag et al. Purified JC virus T antigen derived from insect cells preferentially interacts with binding site II of the viral core origin under replication conditions
Kondo et al. Nuclear location of minor capsid protein L2 is required for expression of a reporter plasmid packaged in HPV51 pseudovirions
CA1341329C (fr) Sequences d'adn determinees provenant du genome du papillomavirus, ainsi que leur usage a des fins diagnostiques in vitro ou pour la synthese de compositions antigeniques
EP0942986A1 (fr) Systemes pour determiner des substances actives contre des maladies associees au vph
Becker et al. Papovaviruses
ZHOU et al. L2 N-Terminal Sequence