NO302031B1 - Rekombinant gen omfattende en nukleotidsekvens som koder for et flagellinfusjonsprotein, genmodifisert mikroorganisme omfattende det rekombinante genet og fremgangsmåte for ekspresjon av det - Google Patents

Rekombinant gen omfattende en nukleotidsekvens som koder for et flagellinfusjonsprotein, genmodifisert mikroorganisme omfattende det rekombinante genet og fremgangsmåte for ekspresjon av det Download PDF

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Publication number
NO302031B1
NO302031B1 NO904806A NO904806A NO302031B1 NO 302031 B1 NO302031 B1 NO 302031B1 NO 904806 A NO904806 A NO 904806A NO 904806 A NO904806 A NO 904806A NO 302031 B1 NO302031 B1 NO 302031B1
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NO
Norway
Prior art keywords
flagellin
recombinant
epitope
gene
protein
Prior art date
Application number
NO904806A
Other languages
English (en)
Norwegian (no)
Other versions
NO904806D0 (no
NO904806L (no
Inventor
William Robert Majarian
Bruce Arnold Dunbar Stocker
Salete Maria Cardozo Newton
Original Assignee
American Cyanamid Co
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co, Univ Leland Stanford Junior filed Critical American Cyanamid Co
Publication of NO904806D0 publication Critical patent/NO904806D0/no
Publication of NO904806L publication Critical patent/NO904806L/no
Publication of NO302031B1 publication Critical patent/NO302031B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445Plasmodium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/55Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO904806A 1988-05-05 1990-11-05 Rekombinant gen omfattende en nukleotidsekvens som koder for et flagellinfusjonsprotein, genmodifisert mikroorganisme omfattende det rekombinante genet og fremgangsmåte for ekspresjon av det NO302031B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19057088A 1988-05-05 1988-05-05
PCT/US1989/001932 WO1989010967A1 (fr) 1988-05-05 1989-05-05 Vaccins de flagelline recombinants

Publications (3)

Publication Number Publication Date
NO904806D0 NO904806D0 (no) 1990-11-05
NO904806L NO904806L (no) 1991-01-03
NO302031B1 true NO302031B1 (no) 1998-01-12

Family

ID=22701885

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904806A NO302031B1 (no) 1988-05-05 1990-11-05 Rekombinant gen omfattende en nukleotidsekvens som koder for et flagellinfusjonsprotein, genmodifisert mikroorganisme omfattende det rekombinante genet og fremgangsmåte for ekspresjon av det

Country Status (10)

Country Link
EP (1) EP0419513B1 (fr)
JP (1) JP2793673B2 (fr)
AT (1) ATE121782T1 (fr)
AU (1) AU637049B2 (fr)
CA (1) CA1340817C (fr)
DE (1) DE68922394T2 (fr)
DK (1) DK263390A (fr)
FI (1) FI104638B (fr)
NO (1) NO302031B1 (fr)
WO (1) WO1989010967A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714596A (en) * 1987-11-18 1998-02-03 Chiron Corporation NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus
US6171782B1 (en) 1987-11-18 2001-01-09 Chiron Corporation Antibody compositions to HCV and uses thereof
US5712088A (en) * 1987-11-18 1998-01-27 Chiron Corporation Methods for detecting Hepatitis C virus using polynucleotides specific for same
US6861212B1 (en) 1987-11-18 2005-03-01 Chiron Corporation NANBV diagnostics and vaccines
US5698390A (en) * 1987-11-18 1997-12-16 Chiron Corporation Hepatitis C immunoassays
AU640118B2 (en) * 1988-12-19 1993-08-19 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur Meningococcal class 1 outer-membrane protein vaccine
US7118757B1 (en) 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
US6027729A (en) * 1989-04-20 2000-02-22 Chiron Corporation NANBV Diagnostics and vaccines
EP0551325B1 (fr) * 1990-10-01 2000-03-15 The Minister Of Agriculture Fisheries And Food In Her Britannic Majesty's Gvt. Of The U. K. Of Great Britain And N. Ireland Procede de depistage de la salmonelle
ES2103312T3 (es) * 1990-10-01 1997-09-16 Mini Agriculture & Fisheries Secuencia de polinucleotidos de la salmonella.
GB9101550D0 (en) * 1991-01-24 1991-03-06 Mastico Robert A Antigen-presenting chimaeric protein
IL101639A0 (en) * 1992-04-17 1992-12-30 Yeda Res & Dev Recombinant influenza vaccines
EP1112747B1 (fr) * 1999-12-28 2004-06-16 Akzo Nobel N.V. Vaccin contre les Salmonella n'induisant pas d'anticorps réagissant avec la flagelline ou les flagelles
WO2004055045A1 (fr) * 2002-12-16 2004-07-01 Caf Laboratories Inc. Composition d'antigenes contre les salmonelles et trousse d'essai d'anticorps et vaccin a sous-unite les utilisant
WO2005107381A2 (fr) 2004-05-07 2005-11-17 Hans-Gustaf Ljunggren Adjuvants
AU2005323811B2 (en) * 2004-12-02 2012-07-05 Csir Gram positive bacterial cells comprising a disrupted flagellin gene, flagellin-based fusion proteins and use in removal of metal ions from a liquid
WO2006066214A2 (fr) 2004-12-16 2006-06-22 Wake Forest University Health Sciences Utilisation de la flagelline dans l'immunotherapie de yersinia pestis
JP2008527009A (ja) * 2005-01-19 2008-07-24 バクシネート コーポレーション 病原体関連分子パターンおよび抗原を含む組成物ならびに免疫応答を刺激するためのそれらの使用
AU2007224034B2 (en) 2006-03-07 2012-03-29 Vaxinnate Corporation Compositions that include hemagglutinin, methods of making and methods of use thereof
WO2009128949A2 (fr) 2008-04-18 2009-10-22 Vaxinnate Corporation Compositions de proteines du virus de la dengue et methodes d’utilisation associees
US8932598B2 (en) 2012-08-28 2015-01-13 Vaxinnate Corporation Fusion proteins and methods of use
CN102816246B (zh) * 2012-09-04 2014-07-23 成都蓉生药业有限责任公司 一种人巨细胞病毒免疫原融合蛋白及其制备方法和用途
JP2017530114A (ja) 2014-09-26 2017-10-12 バヴァリアン・ノルディック・アクティーゼルスカブ フラジェリンをコードする組み換えmvaによる鼻腔内免疫のための方法と組成物
EP3221464B1 (fr) * 2014-11-18 2022-02-23 The Trustees of Columbia University in the City of New York Détection d'analytes à l'aide de cellules vivantes
CN104402974B (zh) * 2014-12-10 2017-11-14 重庆医科大学 一种具有粘膜免疫佐剂活性的多肽及其在制备粘膜免疫佐剂中的用途
US10849938B2 (en) 2017-09-13 2020-12-01 ZBiotics Company Gene expression system for probiotic microorganisms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735801A (en) * 1982-09-07 1988-04-05 Board Of Trustees Of Leland Stanford Jr. University Novel non-reverting salmonella live vaccines
EP0241546A4 (fr) * 1985-10-11 1988-11-02 Genetics Inst Procede de production de proteines heterologues.
EP0237045B1 (fr) * 1986-03-11 1993-10-20 Shionogi & Co., Ltd. ADN codant pour la flagelline et vecteur le contenant
CA1331355C (fr) * 1986-04-21 1994-08-09 Bioenterprises Pty. Ltd Immunopotentialisation

Also Published As

Publication number Publication date
ATE121782T1 (de) 1995-05-15
JP2793673B2 (ja) 1998-09-03
AU3697989A (en) 1989-11-29
FI104638B (fi) 2000-03-15
AU637049B2 (en) 1993-05-20
DK263390A (da) 1991-01-04
JPH04502402A (ja) 1992-05-07
DE68922394D1 (de) 1995-06-01
NO904806D0 (no) 1990-11-05
CA1340817C (fr) 1999-11-09
FI905441A0 (fi) 1990-11-02
NO904806L (no) 1991-01-03
DK263390D0 (da) 1990-11-02
EP0419513B1 (fr) 1995-04-26
DE68922394T2 (de) 1995-10-05
WO1989010967A1 (fr) 1989-11-16
EP0419513A1 (fr) 1991-04-03

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