NO301763B1 - Eventuelt substituerte pyrido-[2,3-d]-pyrimidin-2,4-(1H,3H)-dioner og pyrido-[2,3-d]pyrimidin-2-(1H,3H)-oner, anvendelse av slike for fremstilling av legemidler, samt farmasöytiske preparater inneholdende slike - Google Patents
Eventuelt substituerte pyrido-[2,3-d]-pyrimidin-2,4-(1H,3H)-dioner og pyrido-[2,3-d]pyrimidin-2-(1H,3H)-oner, anvendelse av slike for fremstilling av legemidler, samt farmasöytiske preparater inneholdende slikeInfo
- Publication number
- NO301763B1 NO301763B1 NO943456A NO943456A NO301763B1 NO 301763 B1 NO301763 B1 NO 301763B1 NO 943456 A NO943456 A NO 943456A NO 943456 A NO943456 A NO 943456A NO 301763 B1 NO301763 B1 NO 301763B1
- Authority
- NO
- Norway
- Prior art keywords
- pyrimidine
- pyrido
- dione
- pharmaceuticals
- ones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/855,179 US5264437A (en) | 1992-03-20 | 1992-03-20 | Optionally substituted pyrido[2,3-d]pyridine-2,4(1H,3H)-diones and pyrido[2,]pyrimidine-2(1H,3H)-ones |
PCT/US1993/002273 WO1993019068A1 (en) | 1992-03-20 | 1993-03-18 | PYRIDO[2,3-d]PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS |
Publications (3)
Publication Number | Publication Date |
---|---|
NO943456D0 NO943456D0 (no) | 1994-09-16 |
NO943456L NO943456L (no) | 1994-09-16 |
NO301763B1 true NO301763B1 (no) | 1997-12-08 |
Family
ID=25320543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO943456A NO301763B1 (no) | 1992-03-20 | 1994-09-16 | Eventuelt substituerte pyrido-[2,3-d]-pyrimidin-2,4-(1H,3H)-dioner og pyrido-[2,3-d]pyrimidin-2-(1H,3H)-oner, anvendelse av slike for fremstilling av legemidler, samt farmasöytiske preparater inneholdende slike |
Country Status (16)
Country | Link |
---|---|
US (1) | US5264437A (no) |
EP (2) | EP0631580A1 (no) |
JP (1) | JP3241384B2 (no) |
KR (1) | KR100274104B1 (no) |
CN (1) | CN1040327C (no) |
AU (1) | AU669520B2 (no) |
CA (1) | CA2132297C (no) |
FI (1) | FI106960B (no) |
HU (2) | HUT67552A (no) |
IL (1) | IL105092A (no) |
MX (1) | MX9301530A (no) |
NO (1) | NO301763B1 (no) |
NZ (1) | NZ251525A (no) |
TW (1) | TW240226B (no) |
WO (1) | WO1993019068A1 (no) |
ZA (1) | ZA931945B (no) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
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US5672622A (en) * | 1994-04-21 | 1997-09-30 | Berlex Laboratories, Inc. | Treatment of multiple sclerosis |
US6060501A (en) * | 1994-06-02 | 2000-05-09 | Schering Aktiengesellschaft | Combined treatment of multiple sclerosis |
HUT76980A (hu) * | 1994-08-29 | 1998-01-28 | Yamanouchi Pharmaceutical Co. Ltd. | Új naftiridinszármazékok és ezeket a vegyületeket tartalmazó gyógyászati készítmények |
HUP9702408A3 (en) * | 1995-02-10 | 2000-08-28 | Schering Ag | Use of 5-phenyloxazolidin-2-one derivatives for the preparation of pharmaceutical compositions treating diseases requiring tumour necrosis factor (tnf) inhibition |
DE19540475A1 (de) * | 1995-10-20 | 1997-04-24 | Schering Ag | Chirale Methylphenyloxazolidinone |
NZ322197A (en) * | 1995-11-21 | 1999-02-25 | Yamanouchi Pharma Co Ltd | Pyrido[2,3-d] pyrimidine derivatives and pharmaceutical compositions thereof |
JP2000119272A (ja) * | 1998-10-15 | 2000-04-25 | Nippon Zoki Pharmaceut Co Ltd | 新規7−アミノピリド〔2,3−d〕ピリミジン誘導体 |
US6455554B1 (en) | 1999-06-07 | 2002-09-24 | Targacept, Inc. | Oxopyridinyl pharmaceutical compositions and methods for use |
SK287231B6 (sk) | 1999-08-21 | 2010-04-07 | Nycomed Gmbh | Liečivo zahŕňajúce PDE inhibítor a agonistu beta2 adrenoreceptora |
TWI243055B (en) | 2000-04-13 | 2005-11-11 | Nippon Zoki Pharmaceutical Co | Pharmaceutical composition for use in treatment of dermatitis |
US6825180B2 (en) | 2001-05-18 | 2004-11-30 | Cell Therapeutics, Inc. | Pyridopyrimidine compounds and their uses |
US7183288B2 (en) * | 2001-11-01 | 2007-02-27 | Herwig Josephus Margareta Janssen, legal representative | Amide derivatives as glycogen synthase kinase 3-β inhibitors |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
BRPI0409229A (pt) | 2003-04-01 | 2006-03-28 | Applied Research Systems | inibidores das fosfodiesterases na infertilidade |
WO2006019965A2 (en) * | 2004-07-16 | 2006-02-23 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
TW200726767A (en) * | 2005-07-04 | 2007-07-16 | Astrazeneca Ab | Chemical compounds 2 |
TW200800997A (en) * | 2006-03-22 | 2008-01-01 | Astrazeneca Ab | Chemical compounds |
PT2074122E (pt) * | 2006-09-15 | 2011-08-24 | Pfizer Prod Inc | Compostos de pirido(2,3-d)-pirimidinona e sua utilização como inibidores de pi3 |
TW200835497A (en) * | 2007-01-11 | 2008-09-01 | Astrazeneca Ab | Chemical compounds 636 |
WO2008084236A1 (en) * | 2007-01-11 | 2008-07-17 | Astrazeneca Ab | Chemical compounds 635 : pyridopyrimidinediones as pde4 inhibitors |
SA08280783B1 (ar) * | 2007-01-11 | 2011-04-24 | استرازينيكا ايه بي | مشتقات بيريدوبيريميدين كمثبطات pde4 |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
CA2688161C (en) | 2007-06-04 | 2020-10-20 | Kunwar Shailubhai | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
FR2921926B1 (fr) * | 2007-10-03 | 2009-12-04 | Sanofi Aventis | Derives de quinazolinedione,leur preparation et leurs applications therapeutiques. |
MX2010012492A (es) | 2008-05-27 | 2010-12-21 | Astrazeneca Ab | Derivados de fenoxipiridinilamida y su uso en el tratamiento de estados de enfermedad mediados por fosfodiesterasa 4. |
ES2522968T3 (es) | 2008-06-04 | 2014-11-19 | Synergy Pharmaceuticals Inc. | Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
FR2944282B1 (fr) | 2009-04-09 | 2013-05-03 | Sanofi Aventis | Derives de quinazolinedione, leur preparation et leurs diverses applications therapeutiques |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
CN108676076A (zh) | 2011-03-01 | 2018-10-19 | 辛纳吉制药公司 | 制备鸟苷酸环化酶c激动剂的方法 |
WO2014131024A2 (en) | 2013-02-25 | 2014-08-28 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法 |
MX2016001714A (es) | 2013-08-09 | 2016-10-03 | Ardelyx Inc | Compuestos y metodos para inhibir el transporte de fosfato. |
WO2020237096A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
WO2023042879A1 (ja) * | 2021-09-17 | 2023-03-23 | 塩野義製薬株式会社 | ウイルス増殖阻害活性を有する二環性複素環誘導体およびそれらを含有する医薬組成物 |
CN113831491B (zh) * | 2021-09-30 | 2023-03-24 | 南昌大学 | 一种嘧啶唑共价有机框架的制备方法及吸附应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5649917B2 (no) * | 1973-12-18 | 1981-11-25 | ||
DE2523730A1 (de) * | 1974-06-12 | 1976-02-12 | Hisamitsu Pharmaceutical Co | Pyrido eckige klammer auf 2,3-d eckige klammer zu pyrimidinonen |
JPS58428B2 (ja) * | 1974-07-05 | 1983-01-06 | ヒサミツセイヤク カブシキガイシヤ | シンキナ 2− オキソ −1,2,3,4− テトラヒドロピリド ( 2,3−d ) ピリミジンユウドウタイノ セイゾウホウ |
DE3770095D1 (de) * | 1986-08-21 | 1991-06-20 | Pfizer | Chinazolindione und pyridopyrimidindione. |
AU4220193A (en) * | 1992-04-29 | 1993-11-29 | Sri International | Deazaaminopterins for treatment of inflammation |
-
1992
- 1992-03-20 US US07/855,179 patent/US5264437A/en not_active Expired - Lifetime
-
1993
- 1993-03-18 NZ NZ251525A patent/NZ251525A/en unknown
- 1993-03-18 EP EP93908322A patent/EP0631580A1/en not_active Ceased
- 1993-03-18 CA CA002132297A patent/CA2132297C/en not_active Expired - Fee Related
- 1993-03-18 MX MX9301530A patent/MX9301530A/es not_active IP Right Cessation
- 1993-03-18 ZA ZA931945A patent/ZA931945B/xx unknown
- 1993-03-18 WO PCT/US1993/002273 patent/WO1993019068A1/en active IP Right Grant
- 1993-03-18 IL IL105092A patent/IL105092A/en not_active IP Right Cessation
- 1993-03-18 TW TW082101993A patent/TW240226B/zh active
- 1993-03-18 CN CN93103352A patent/CN1040327C/zh not_active Expired - Fee Related
- 1993-03-18 HU HU9402653A patent/HUT67552A/hu unknown
- 1993-03-18 AU AU39186/93A patent/AU669520B2/en not_active Ceased
- 1993-03-18 JP JP51663493A patent/JP3241384B2/ja not_active Expired - Fee Related
- 1993-03-18 EP EP05023665A patent/EP1770093A1/en not_active Withdrawn
- 1993-03-18 KR KR1019940703294A patent/KR100274104B1/ko not_active IP Right Cessation
-
1994
- 1994-09-16 FI FI944305A patent/FI106960B/fi not_active IP Right Cessation
- 1994-09-16 NO NO943456A patent/NO301763B1/no not_active IP Right Cessation
-
1995
- 1995-04-24 HU HU95P/P00114P patent/HU210873A9/hu unknown
Also Published As
Publication number | Publication date |
---|---|
ZA931945B (en) | 1994-09-18 |
TW240226B (no) | 1995-02-11 |
KR100274104B1 (ko) | 2000-12-15 |
IL105092A0 (en) | 1993-07-08 |
FI106960B (fi) | 2001-05-15 |
NZ251525A (en) | 1996-09-25 |
IL105092A (en) | 1998-06-15 |
EP1770093A1 (en) | 2007-04-04 |
MX9301530A (es) | 1994-01-31 |
US5264437A (en) | 1993-11-23 |
HU210873A9 (en) | 1995-08-28 |
HU9402653D0 (en) | 1994-11-28 |
CN1040327C (zh) | 1998-10-21 |
FI944305A0 (fi) | 1994-09-16 |
AU669520B2 (en) | 1996-06-13 |
CN1078470A (zh) | 1993-11-17 |
AU3918693A (en) | 1993-10-21 |
CA2132297A1 (en) | 1993-09-30 |
NO943456D0 (no) | 1994-09-16 |
NO943456L (no) | 1994-09-16 |
HUT67552A (en) | 1995-04-28 |
FI944305A (fi) | 1994-09-16 |
EP0631580A1 (en) | 1995-01-04 |
JP3241384B2 (ja) | 2001-12-25 |
WO1993019068A1 (en) | 1993-09-30 |
KR950700909A (ko) | 1995-02-20 |
CA2132297C (en) | 2006-01-03 |
JPH07504676A (ja) | 1995-05-25 |
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Legal Events
Date | Code | Title | Description |
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MM1K | Lapsed by not paying the annual fees |