NO300465B1 - Fremgangsmåte til fremstilling av terapeutisk aktive antigene HBV-partikler som består av S- og preS2-proteiner - Google Patents
Fremgangsmåte til fremstilling av terapeutisk aktive antigene HBV-partikler som består av S- og preS2-proteiner Download PDFInfo
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- NO300465B1 NO300465B1 NO891921A NO891921A NO300465B1 NO 300465 B1 NO300465 B1 NO 300465B1 NO 891921 A NO891921 A NO 891921A NO 891921 A NO891921 A NO 891921A NO 300465 B1 NO300465 B1 NO 300465B1
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- gene
- isolated
- operably linked
- pres2
- pichia pastoris
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19371488A | 1988-05-13 | 1988-05-13 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO891921D0 NO891921D0 (no) | 1989-05-11 |
| NO891921L NO891921L (no) | 1989-11-14 |
| NO300465B1 true NO300465B1 (no) | 1997-06-02 |
Family
ID=22714736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO891921A NO300465B1 (no) | 1988-05-13 | 1989-05-11 | Fremgangsmåte til fremstilling av terapeutisk aktive antigene HBV-partikler som består av S- og preS2-proteiner |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US5650296A (fr) |
| EP (1) | EP0341746B1 (fr) |
| JP (1) | JP2614314B2 (fr) |
| KR (1) | KR100193701B1 (fr) |
| CN (1) | CN1038668A (fr) |
| AT (1) | ATE151109T1 (fr) |
| AU (1) | AU618596B2 (fr) |
| CA (1) | CA1340617C (fr) |
| DD (1) | DD285373A5 (fr) |
| DE (1) | DE68927921T2 (fr) |
| DK (1) | DK235289A (fr) |
| ES (1) | ES2101676T3 (fr) |
| FI (2) | FI104639B (fr) |
| GR (1) | GR3023985T3 (fr) |
| HU (1) | HU207532B (fr) |
| IE (1) | IE81158B1 (fr) |
| IL (1) | IL90161A0 (fr) |
| IN (1) | IN171696B (fr) |
| MX (1) | MX26715A (fr) |
| NO (1) | NO300465B1 (fr) |
| NZ (1) | NZ228948A (fr) |
| PL (1) | PL161997B1 (fr) |
| PT (1) | PT90553A (fr) |
| YU (1) | YU98689A (fr) |
| ZA (1) | ZA893440B (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5032516A (en) * | 1985-10-25 | 1991-07-16 | Phillips Petroleum Company | Pichia pastoris alcohol oxidase II regulatory region |
| PL168787B1 (pl) * | 1989-08-03 | 1996-04-30 | Smithkline Beecham Biolog | Sposób wytwarzania czastki kompozytowej PL |
| US6197548B1 (en) | 1990-04-02 | 2001-03-06 | Medeva Pharma Limited | Transformed Pichia expressing the pertactin antigen |
| GB9007416D0 (en) * | 1990-04-02 | 1990-05-30 | Wellcome Found | Expression of heterologous protein in yeast |
| EP0521348A1 (fr) * | 1991-06-18 | 1993-01-07 | Korea Institute Of Science And Technology | Anticorps chimérique à spécificité envers l'antigène de surface pré-S2 du virus de l'hépatite B et lignée cellulaire le produisant |
| LT3988B (en) | 1992-02-17 | 1996-06-25 | Fermentas Biotech Inst | Recombinant plasmides pfs19, pfps2-48 and pjlfds1 codingsynthesis of human hepatite b of surfice virus antigenes, methods fof producing thereof |
| CA2101610A1 (fr) * | 1992-08-07 | 1994-02-08 | William D. Prevatt | Production d'entomotoxines de bacillus dans des levures methylotrophes |
| GB9402832D0 (en) * | 1994-02-15 | 1994-04-06 | Smith Kline Beecham Biolog S A | Novel process |
| US5716808A (en) * | 1995-11-09 | 1998-02-10 | Zymogenetics, Inc. | Genetic engineering of pichia methanolica |
| US5955349A (en) * | 1996-08-26 | 1999-09-21 | Zymogenetics, Inc. | Compositions and methods for producing heterologous polypeptides in Pichia methanolica |
| WO1997017450A2 (fr) * | 1995-11-09 | 1997-05-15 | Zymogenetics, Inc. | Compositions et procedes de production de polypeptides heterologues sur pichia methanolica |
| MX9605082A (es) | 1996-10-24 | 1998-04-30 | Univ Autonoma De Nuevo Leon | Levaduras metilotroficas modificadas geneticamente para la produccion y secrecion de hormona de crecimiento humano. |
| JP2008500364A (ja) * | 2004-05-25 | 2008-01-10 | キメラコア， インコーポレイテッド | 自己集合性ナノ粒子薬物送達システム |
| CN1704475A (zh) * | 2004-05-31 | 2005-12-07 | 成都生物制品研究所 | 羧端含前s2免疫决定簇的乙肝表面抗原融合基因及蛋白质 |
| EP1773861A4 (fr) * | 2004-07-22 | 2008-04-16 | Glycofi Inc | Sequences de regulation de malate synthase pour l'expression d'un gene heterologue chez pichia |
| CN100381171C (zh) * | 2004-12-30 | 2008-04-16 | 成都生物制品研究所 | 含前s1、前s2和s抗原决定簇的乙肝表面抗原复合颗粒 |
| ATE460922T1 (de) * | 2006-04-07 | 2010-04-15 | Chimeros Inc | Zusammensetzungen und verfahren zur behandlung von b-zellen-malignomen |
| CA2683063A1 (fr) * | 2007-04-09 | 2008-10-16 | Chimeros, Inc. | Systeme de relargage de medicaments par auto-assemblage de nanoparticules |
| WO2010120874A2 (fr) | 2009-04-14 | 2010-10-21 | Chimeros, Inc. | Agents thérapeutiques chimériques, compositions, et leurs procédés d'utilisation |
| AU2012305714A1 (en) | 2011-09-09 | 2014-03-27 | Biomed Realty, L.P. | Methods and compositions for controlling assembly of viral proteins |
| ES2926021T3 (es) | 2012-10-23 | 2022-10-21 | Toolgen Inc | Composición para escindir un ADN objetivo que comprende un ARN guía específico para el ADN objetivo y ácido nucleico codificador de proteína Cas o proteína Cas, y uso de la misma |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR76274B (fr) * | 1981-08-04 | 1984-08-04 | Univ California | |
| EP0401941A3 (fr) * | 1984-07-11 | 1991-04-17 | Takeda Chemical Industries, Ltd. | Antigène de surface du virus de l'hépatite B, et sa production |
| US4895800A (en) * | 1985-11-26 | 1990-01-23 | Phillips Petroleum Company | Yeast production of hepatitis B surface antigen |
| US4816564A (en) * | 1986-01-31 | 1989-03-28 | Merck & Co., Inc. | Method for producing hepatitis B virus proteins in yeast |
| JPS62236496A (ja) * | 1986-04-07 | 1987-10-16 | Green Cross Corp:The | ＨＢｓＡｇの製造方法 |
| US4963483A (en) * | 1987-10-13 | 1990-10-16 | Merck & Co., Inc. | Method for producing hepatitis B virus proteins in yeast |
| NZ228774A (en) * | 1988-04-25 | 1991-05-28 | Phillips Petroleum Co | Hbv particles containing pres 2 proteins and recombinant processes for their production in yeast cells |
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1989
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- 1989-05-12 FI FI892312A patent/FI104639B/fi active IP Right Grant
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- 1989-05-13 CN CN89103330A patent/CN1038668A/zh active Pending
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1995
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1997
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