NO2773633T3 - - Google Patents

Info

Publication number
NO2773633T3
NO2773633T3 NO12777930A NO12777930A NO2773633T3 NO 2773633 T3 NO2773633 T3 NO 2773633T3 NO 12777930 A NO12777930 A NO 12777930A NO 12777930 A NO12777930 A NO 12777930A NO 2773633 T3 NO2773633 T3 NO 2773633T3
Authority
NO
Norway
Application number
NO12777930A
Other languages
Norwegian (no)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NO2773633T3 publication Critical patent/NO2773633T3/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO12777930A 2011-11-02 2012-10-29 NO2773633T3 (enrdf_load_stackoverflow)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11187553 2011-11-02
PCT/EP2012/071352 WO2013064450A1 (en) 2011-11-02 2012-10-29 Heterocyclic compounds, medicaments containing said compounds, use thereof and processes for the preparation thereof
EP12777930.4A EP2773633B1 (en) 2011-11-02 2012-10-29 Heterocyclic compounds, medicaments containing said compounds, use thereof and processes for the preparation thereof

Publications (1)

Publication Number Publication Date
NO2773633T3 true NO2773633T3 (enrdf_load_stackoverflow) 2017-12-30

Family

ID=47073464

Family Applications (1)

Application Number Title Priority Date Filing Date
NO12777930A NO2773633T3 (enrdf_load_stackoverflow) 2011-11-02 2012-10-29

Country Status (34)

Country Link
US (4) US8759349B2 (enrdf_load_stackoverflow)
EP (1) EP2773633B1 (enrdf_load_stackoverflow)
JP (1) JP6091513B2 (enrdf_load_stackoverflow)
KR (1) KR102006612B1 (enrdf_load_stackoverflow)
CN (2) CN106279110B (enrdf_load_stackoverflow)
AP (1) AP2014007670A0 (enrdf_load_stackoverflow)
AU (1) AU2012331274B2 (enrdf_load_stackoverflow)
BR (1) BR112014010583A2 (enrdf_load_stackoverflow)
CA (1) CA2854217C (enrdf_load_stackoverflow)
CL (1) CL2014001047A1 (enrdf_load_stackoverflow)
CO (1) CO6940429A2 (enrdf_load_stackoverflow)
CY (1) CY1120974T1 (enrdf_load_stackoverflow)
DK (1) DK2773633T3 (enrdf_load_stackoverflow)
EA (1) EA025158B9 (enrdf_load_stackoverflow)
EC (1) ECSP14001929A (enrdf_load_stackoverflow)
ES (1) ES2645744T3 (enrdf_load_stackoverflow)
GE (1) GEP20186880B (enrdf_load_stackoverflow)
HR (1) HRP20171614T1 (enrdf_load_stackoverflow)
HU (1) HUE034929T2 (enrdf_load_stackoverflow)
IL (1) IL232035A (enrdf_load_stackoverflow)
LT (1) LT2773633T (enrdf_load_stackoverflow)
ME (1) ME02905B (enrdf_load_stackoverflow)
MX (1) MX348522B (enrdf_load_stackoverflow)
NO (1) NO2773633T3 (enrdf_load_stackoverflow)
PE (1) PE20141607A1 (enrdf_load_stackoverflow)
PH (1) PH12014500970B1 (enrdf_load_stackoverflow)
PL (1) PL2773633T3 (enrdf_load_stackoverflow)
PT (1) PT2773633T (enrdf_load_stackoverflow)
RS (1) RS56498B1 (enrdf_load_stackoverflow)
SG (1) SG11201401907TA (enrdf_load_stackoverflow)
SI (1) SI2773633T1 (enrdf_load_stackoverflow)
TN (1) TN2014000180A1 (enrdf_load_stackoverflow)
UA (1) UA115868C2 (enrdf_load_stackoverflow)
WO (1) WO2013064450A1 (enrdf_load_stackoverflow)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2635581C (en) 2005-12-28 2017-02-28 Vertex Pharmaceuticals Incorporated Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
HRP20171614T1 (hr) * 2011-11-02 2017-12-01 Boehringer Ingelheim International Gmbh Heterociklički spojevi, lijekovi koji sadrže te spojeve, njihova primjena i postupci za njihovu proizvodnju
CN105518000B (zh) * 2013-07-02 2018-09-14 加州生物医学研究所 用于治疗囊性纤维化的化合物
WO2015003958A1 (en) * 2013-07-08 2015-01-15 Boehringer Ingelheim International Gmbh Amiloride-type compounds as inhibitors in epithelial sodium channels for the treatment of diseases of the lungs and airways
US9701639B2 (en) 2014-10-07 2017-07-11 Vertex Pharmaceuticals Incorporated Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator
ES2871673T3 (es) * 2014-10-24 2021-10-29 Ono Pharmaceutical Co Activador de los canales KCNQ2-5
WO2016112120A1 (en) * 2015-01-07 2016-07-14 The California Institute For Biomedical Research Compounds for treatment of cystic fibrosis
GB201610854D0 (en) 2016-06-21 2016-08-03 Entpr Therapeutics Ltd Compounds
GB201619694D0 (en) 2016-11-22 2017-01-04 Entpr Therapeutics Ltd Compounds
GB201717051D0 (en) 2017-10-17 2017-11-29 Enterprise Therapeutics Ltd Compounds
GB201808093D0 (en) 2018-05-18 2018-07-04 Enterprise Therapeutics Ltd Compounds
WO2022053651A2 (en) 2020-09-10 2022-03-17 Precirix N.V. Antibody fragment against fap
CN112107580A (zh) * 2020-09-29 2020-12-22 北京鑫开元医药科技有限公司 一种脾酪氨酸激酶抑制剂的制剂组合物及其制备方法
WO2023203135A1 (en) 2022-04-22 2023-10-26 Precirix N.V. Improved radiolabelled antibody
EP4518911A1 (en) 2022-05-02 2025-03-12 Precirix N.V. Pre-targeting
WO2024243025A1 (en) * 2023-05-19 2024-11-28 Ikena Oncology, Inc. Naphthyl-substituted pyrido[4,3-d]pyrimidines and related compounds and their use in treating medical conditions

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6812003A (enrdf_load_stackoverflow) 1967-09-07 1969-03-11
US3953476A (en) 1971-12-27 1976-04-27 Merck & Co., Inc. 3-Amino-5-sulfonylbenzoic acids
AU774865B2 (en) 1999-07-19 2004-07-08 University Of North Carolina At Chapel Hill, The Conjugates of sodium channel blockers and methods of using the same
WO2001052902A1 (en) 2000-01-24 2001-07-26 Isis Pharmaceuticals, Inc. Antisense modulation of inducible nitric oxide synthase expression
EP1786427A4 (en) 2004-08-18 2009-11-11 Michael R Johnson BLOCKERS OF SODIUM CHANNELS OF PYRAZINOYLGUANIDINE WITH AMIDE AND ALIPHATIC ESTER
GB0526244D0 (en) * 2005-12-22 2006-02-01 Novartis Ag Organic compounds
EP2484308A1 (en) * 2006-07-24 2012-08-08 International Stem Cell Corporation Synthetic cornea from retinal stem cells
EP2332933A1 (en) * 2007-05-07 2011-06-15 Novartis AG Epithelial sodium channel (ENaC) inhibitors
MX2010006421A (es) 2007-12-10 2010-06-25 Novartis Ag Compuestos organicos.
CA2723938A1 (en) 2008-05-13 2009-11-19 Novartis Ag 3,5-diamino-6-chloro-pyrazine-2-carboxylic acid derivatives and their use as epithelial sodium channel blockers for the treatment of airway diseases
CN102112130A (zh) 2008-06-10 2011-06-29 诺瓦提斯公司 作为上皮钠通道阻滞剂的吡嗪衍生物
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
US9050339B2 (en) 2010-09-17 2015-06-09 Novartis Ag Pyrazine derivatives as ENaC blockers
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
HUE032851T2 (en) 2011-06-27 2017-11-28 Parion Sciences Inc A chemically and metabolically stable dipeptide having strong sodium channel blocking activity
HRP20171614T1 (hr) * 2011-11-02 2017-12-01 Boehringer Ingelheim International Gmbh Heterociklički spojevi, lijekovi koji sadrže te spojeve, njihova primjena i postupci za njihovu proizvodnju
CN104024231A (zh) 2011-11-02 2014-09-03 勃林格殷格翰国际有限公司 制备酰基胍和酰基硫脲化合物的新方法

Also Published As

Publication number Publication date
TN2014000180A1 (en) 2015-09-30
WO2013064450A1 (en) 2013-05-10
AP2014007670A0 (en) 2014-05-31
PT2773633T (pt) 2017-11-14
RS56498B1 (sr) 2018-01-31
LT2773633T (lt) 2017-11-10
CA2854217A1 (en) 2013-05-10
NZ622469A (en) 2016-08-26
PL2773633T3 (pl) 2018-01-31
EA201400521A1 (ru) 2014-09-30
CA2854217C (en) 2019-12-31
PH12014500970B1 (en) 2017-10-06
HUE034929T2 (en) 2018-03-28
ME02905B (me) 2018-10-20
KR102006612B1 (ko) 2019-08-02
SI2773633T1 (sl) 2017-11-30
DK2773633T3 (da) 2017-11-13
EP2773633B1 (en) 2017-08-02
HRP20171614T1 (hr) 2017-12-01
EP2773633A1 (en) 2014-09-10
UA115868C2 (uk) 2018-01-10
AU2012331274A1 (en) 2014-04-03
US8759349B2 (en) 2014-06-24
PE20141607A1 (es) 2014-11-23
CN104024244A (zh) 2014-09-03
ECSP14001929A (es) 2015-11-30
SG11201401907TA (en) 2014-05-29
US20150336933A1 (en) 2015-11-26
JP6091513B2 (ja) 2017-03-08
GEP20186880B (en) 2018-07-25
MX348522B (es) 2017-06-16
US9920035B2 (en) 2018-03-20
CN106279110B (zh) 2019-12-10
EA025158B1 (ru) 2016-11-30
JP2014534222A (ja) 2014-12-18
PH12014500970A1 (en) 2014-06-09
EA025158B9 (ru) 2018-03-30
BR112014010583A2 (pt) 2020-04-22
IL232035A (en) 2017-05-29
CN106279110A (zh) 2017-01-04
HK1196819A1 (zh) 2014-12-24
CN104024244B (zh) 2016-09-14
US20130109697A1 (en) 2013-05-02
CL2014001047A1 (es) 2014-11-07
ES2645744T3 (es) 2017-12-07
CO6940429A2 (es) 2014-05-09
CY1120974T1 (el) 2019-12-11
US20180194747A1 (en) 2018-07-12
IL232035A0 (en) 2014-05-28
AU2012331274B2 (en) 2017-06-08
KR20140085498A (ko) 2014-07-07
US20140228374A1 (en) 2014-08-14
MX2014005166A (es) 2014-05-28

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