NO2723764T3 - - Google Patents
Info
- Publication number
- NO2723764T3 NO2723764T3 NO12730478A NO12730478A NO2723764T3 NO 2723764 T3 NO2723764 T3 NO 2723764T3 NO 12730478 A NO12730478 A NO 12730478A NO 12730478 A NO12730478 A NO 12730478A NO 2723764 T3 NO2723764 T3 NO 2723764T3
- Authority
- NO
- Norway
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4722—G-proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11181357 | 2011-09-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO2723764T3 true NO2723764T3 (no) | 2018-05-26 |
Family
ID=47423019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO12730478A NO2723764T3 (no) | 2011-09-15 | 2012-06-21 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US9695227B2 (no) |
| EP (3) | EP3345919A1 (no) |
| JP (2) | JP6164535B2 (no) |
| CN (2) | CN107857810A (no) |
| AU (1) | AU2012273987B2 (no) |
| CA (1) | CA2839834A1 (no) |
| DK (1) | DK2723764T3 (no) |
| ES (1) | ES2662372T3 (no) |
| HR (1) | HRP20180443T1 (no) |
| HU (1) | HUE036982T2 (no) |
| NO (1) | NO2723764T3 (no) |
| PL (1) | PL2723764T3 (no) |
| PT (1) | PT2723764T (no) |
| WO (1) | WO2012175643A2 (no) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201014715D0 (en) | 2010-09-06 | 2010-10-20 | Vib Vzw | Nanobodies stabilizing functional conformational states of GPCRS |
| JP6164535B2 (ja) | 2011-06-21 | 2017-07-19 | フエー・イー・ベー・フエー・ゼツト・ウエー | Ｇｐｃｒ：ｇタンパク質複合体に対して作製された結合ドメインおよびそれに由来する使用 |
| EP2867674B1 (en) | 2012-06-28 | 2018-10-10 | UCB Biopharma SPRL | A method for identifying compounds of therapeutic interest |
| TWI646230B (zh) | 2013-08-05 | 2019-01-01 | 扭轉生物科技有限公司 | 重新合成之基因庫 |
| WO2016001417A1 (en) * | 2014-07-04 | 2016-01-07 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anti- mglur2 conformational single domain antibodies and uses thereof |
| WO2016067094A2 (en) | 2014-10-27 | 2016-05-06 | King Abdullah University Of Science And Technology | Methods and systems for identifying ligand-protein binding sites |
| CA2975852A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| US9981239B2 (en) | 2015-04-21 | 2018-05-29 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| CA2998169A1 (en) | 2015-09-18 | 2017-03-23 | Twist Bioscience Corporation | Oligonucleic acid variant libraries and synthesis thereof |
| CN108698012A (zh) | 2015-09-22 | 2018-10-23 | 特韦斯特生物科学公司 | 用于核酸合成的柔性基底 |
| EP3384077A4 (en) | 2015-12-01 | 2019-05-08 | Twist Bioscience Corporation | FUNCTIONALIZED SURFACES AND THEIR PREPARATION |
| CN105802970A (zh) * | 2016-05-30 | 2016-07-27 | 东北师范大学 | 靶向沉默Gβ1的shRNA |
| KR102212257B1 (ko) | 2016-08-22 | 2021-02-04 | 트위스트 바이오사이언스 코포레이션 | 드 노보 합성된 핵산 라이브러리 |
| US10417457B2 (en) | 2016-09-21 | 2019-09-17 | Twist Bioscience Corporation | Nucleic acid based data storage |
| CN107037116B (zh) * | 2016-12-01 | 2019-04-23 | 白波 | 检测gpcr之间相互作用及其交界面的方法 |
| US10907274B2 (en) | 2016-12-16 | 2021-02-02 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| US11550939B2 (en) | 2017-02-22 | 2023-01-10 | Twist Bioscience Corporation | Nucleic acid based data storage using enzymatic bioencryption |
| US10894959B2 (en) | 2017-03-15 | 2021-01-19 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| EP3638782A4 (en) | 2017-06-12 | 2021-03-17 | Twist Bioscience Corporation | SEALLESS NUCLEIC ACID ASSEMBLY METHODS |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| CN111566125A (zh) * | 2017-09-11 | 2020-08-21 | 特韦斯特生物科学公司 | Gpcr结合蛋白及其合成 |
| KR20240024357A (ko) | 2017-10-20 | 2024-02-23 | 트위스트 바이오사이언스 코포레이션 | 폴리뉴클레오타이드 합성을 위한 가열된 나노웰 |
| WO2019086548A1 (en) | 2017-10-31 | 2019-05-09 | Vib Vzw | Novel antigen-binding chimeric proteins and methods and uses thereof |
| SG11202001226PA (en) * | 2017-12-21 | 2020-03-30 | Firmenich & Cie | Method for identifying positive allosteric modulators for odorant receptors |
| US10936953B2 (en) | 2018-01-04 | 2021-03-02 | Twist Bioscience Corporation | DNA-based digital information storage with sidewall electrodes |
| WO2019155041A1 (en) * | 2018-02-12 | 2019-08-15 | Vib Vzw | Gβγ COMPLEX ANTIBODIES AND USES THEREOF |
| CN108586620B (zh) * | 2018-05-10 | 2021-11-23 | 山东大学 | 筛选昆虫性信息素受体的配体的传感器分子以及筛选方法 |
| EP3814497A4 (en) | 2018-05-18 | 2022-03-02 | Twist Bioscience Corporation | POLYNUCLEOTIDES, REAGENTS, AND METHODS FOR NUCLEIC ACID HYBRIDIZATION |
| FR3084365B1 (fr) * | 2018-07-27 | 2020-10-23 | Cisbio Bioassays | Anticorps a domaine unique qui se lient a la proteine g alpha |
| CN113811542A (zh) * | 2018-12-21 | 2021-12-17 | 非营利性组织佛兰芒综合大学生物技术研究所 | 包含细胞因子和支架蛋白的融合蛋白 |
| FR3092172B1 (fr) | 2019-01-30 | 2021-02-12 | Cisbio Bioassays | Méthode pour mesurer la modulation de l’activation d’un récepteur couplé à une protéine G avec des analogues du GTP |
| SG11202109283UA (en) | 2019-02-26 | 2021-09-29 | Twist Bioscience Corp | Variant nucleic acid libraries for antibody optimization |
| US11492727B2 (en) | 2019-02-26 | 2022-11-08 | Twist Bioscience Corporation | Variant nucleic acid libraries for GLP1 receptor |
| US20220276244A1 (en) * | 2019-04-29 | 2022-09-01 | Confo Therapeutics N.V. | Chimeric proteins and methods to screen for compounds and ligands binding to gpcrs |
| WO2020257405A1 (en) * | 2019-06-18 | 2020-12-24 | Musc Foundation For Research Development | Compositions and methods targeting the nucleotide free state of ras to block oncogenic signaling and transformation |
| EP3987019A4 (en) | 2019-06-21 | 2023-04-19 | Twist Bioscience Corporation | BARCODE-BASED NUCLEIC ACID SEQUENCE ARRANGEMENT |
| FR3106830B1 (fr) | 2020-01-30 | 2022-02-11 | Cisbio Bioassays | Anticorps anti-protéine G alpha |
| WO2023154533A2 (en) * | 2022-02-14 | 2023-08-17 | Twist Bioscience Corporation | Combinatorial dna assembly for multispecific antibodies |
| WO2023159144A2 (en) * | 2022-02-17 | 2023-08-24 | The Regents Of The University Of Michigan | G-protein coupled receptor assay |
| CN114702570B (zh) * | 2022-03-23 | 2022-12-06 | 山东大学 | aGPCR拮抗剂 |
| WO2024083843A1 (en) | 2022-10-18 | 2024-04-25 | Confo Therapeutics N.V. | Amino acid sequences directed against the melanocortin 4 receptor and polypeptides comprising the same for the treatment of mc4r-related diseases and disorders |
| US11862295B1 (en) | 2022-11-08 | 2024-01-02 | United Arab Emirates University | Method of classifying conformers |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1087013T3 (da) | 1992-08-21 | 2009-05-11 | Univ Bruxelles | Immunoglobuliner uden lette kæder |
| US5721121A (en) | 1995-06-06 | 1998-02-24 | Genentech, Inc. | Mammalian cell culture process for producing a tumor necrosis factor receptor immunoglobulin chimeric protein |
| BR9907241A (pt) | 1998-01-26 | 2000-10-17 | Unilever Nv | Biblioteca de expressão, processo para preparar a mesma, uso de uma fonte não imunizada de sequências de ácido nucleico, e, processos para preparar fragmentos de anticorpos e, para preparar um anticorpo |
| WO2000043507A1 (en) | 1999-01-19 | 2000-07-27 | Unilever Plc | Method for producing antibody fragments |
| WO2001090190A2 (en) | 2000-05-26 | 2001-11-29 | National Research Council Of Canada | Single-domain antigen-binding antibody fragments derived from llama antibodies |
| US7294472B2 (en) * | 2001-03-14 | 2007-11-13 | Caden Biosciences | Method for identifying modulators of G protein coupled receptor signaling |
| US7208279B2 (en) | 2001-03-14 | 2007-04-24 | Caden Biosciences, Inc. | Method for identifying inhibitors of G protein coupled receptor signaling |
| GB0110029D0 (en) | 2001-04-24 | 2001-06-13 | Grosveld Frank | Transgenic animal |
| WO2004035614A1 (en) | 2001-07-11 | 2004-04-29 | Karo Bio Ab | Synthetic or partially purified peptides which can bind to specific subunits of g proteins and uses thereof |
| EP1433793A4 (en) | 2001-09-13 | 2006-01-25 | Inst Antibodies Co Ltd | METHOD FOR CREATING A CAMEL ANTIBODY LIBRARY |
| JP2005289809A (ja) | 2001-10-24 | 2005-10-20 | Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) | 突然変異重鎖抗体 |
| GB0228210D0 (en) | 2002-12-03 | 2003-01-08 | Babraham Inst | Single chain antibodies |
| KR101025143B1 (ko) | 2002-12-31 | 2011-04-01 | 넥타르 테라퓨틱스 | 가수분해상으로 안정한 말레이미드－종결 중합체 |
| WO2006086883A1 (en) * | 2005-02-16 | 2006-08-24 | Universite De Montreal | Biosensors for monitoring receptor-mediated g-protein activation |
| AU2007285695B2 (en) | 2006-08-18 | 2012-05-24 | Ablynx N.V. | Amino acid sequences directed against IL-6R and polypeptides comprising the same for the treatment of diseases and disorders associated with IL-6-mediated signalling |
| WO2009051633A1 (en) | 2007-10-15 | 2009-04-23 | The Board Of Trustees Of The Leland Stanford Junior University | Gpcr crystalization method using an antibody |
| EP2285833B1 (en) * | 2008-05-16 | 2014-12-17 | Ablynx N.V. | AMINO ACID SEQUENCES DIRECTED AGAINST CXCR4 AND OTHER GPCRs AND COMPOUNDS COMPRISING THE SAME |
| WO2009147196A1 (en) | 2008-06-04 | 2009-12-10 | Vib Vzw | Hiv-rev-multimerization inhibiting nanobodies |
| WO2010043650A2 (en) * | 2008-10-14 | 2010-04-22 | Ablynx Nv | Amino acid sequences directed against cellular receptors for viruses and bacteria |
| JP2012510806A (ja) | 2008-12-08 | 2012-05-17 | コンプリクス エン ヴェー | 単鎖逆平行コイルドコイルタンパク質 |
| GB201014715D0 (en) * | 2010-09-06 | 2010-10-20 | Vib Vzw | Nanobodies stabilizing functional conformational states of GPCRS |
| JP6164535B2 (ja) | 2011-06-21 | 2017-07-19 | フエー・イー・ベー・フエー・ゼツト・ウエー | Ｇｐｃｒ：ｇタンパク質複合体に対して作製された結合ドメインおよびそれに由来する使用 |
-
2012
- 2012-06-21 JP JP2014516358A patent/JP6164535B2/ja active Active
- 2012-06-21 PL PL12730478T patent/PL2723764T3/pl unknown
- 2012-06-21 CA CA2839834A patent/CA2839834A1/en active Pending
- 2012-06-21 EP EP17209368.4A patent/EP3345919A1/en active Pending
- 2012-06-21 PT PT127304780T patent/PT2723764T/pt unknown
- 2012-06-21 EP EP23193788.9A patent/EP4282882A3/en active Pending
- 2012-06-21 DK DK12730478.0T patent/DK2723764T3/en active
- 2012-06-21 HU HUE12730478A patent/HUE036982T2/hu unknown
- 2012-06-21 EP EP12730478.0A patent/EP2723764B1/en active Active
- 2012-06-21 CN CN201710728087.8A patent/CN107857810A/zh active Pending
- 2012-06-21 AU AU2012273987A patent/AU2012273987B2/en active Active
- 2012-06-21 WO PCT/EP2012/062036 patent/WO2012175643A2/en active Application Filing
- 2012-06-21 ES ES12730478.0T patent/ES2662372T3/es active Active
- 2012-06-21 NO NO12730478A patent/NO2723764T3/no unknown
- 2012-06-21 US US14/129,100 patent/US9695227B2/en active Active
- 2012-06-21 CN CN201280040585.9A patent/CN104053667B/zh active Active
-
2017
- 2017-02-16 JP JP2017026632A patent/JP2017127306A/ja active Pending
- 2017-05-01 US US15/583,540 patent/US10626154B2/en active Active
-
2018
- 2018-03-15 HR HRP20180443TT patent/HRP20180443T1/hr unknown
-
2020
- 2020-04-17 US US16/852,235 patent/US20200239534A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US10626154B2 (en) | 2020-04-21 |
| WO2012175643A2 (en) | 2012-12-27 |
| US20200239534A1 (en) | 2020-07-30 |
| US20140275487A1 (en) | 2014-09-18 |
| WO2012175643A3 (en) | 2013-06-13 |
| CN104053667A (zh) | 2014-09-17 |
| HRP20180443T1 (hr) | 2018-04-20 |
| ES2662372T3 (es) | 2018-04-06 |
| CA2839834A1 (en) | 2012-12-27 |
| AU2012273987B2 (en) | 2017-01-05 |
| JP6164535B2 (ja) | 2017-07-19 |
| US20170253644A1 (en) | 2017-09-07 |
| JP2017127306A (ja) | 2017-07-27 |
| US9695227B2 (en) | 2017-07-04 |
| EP3345919A1 (en) | 2018-07-11 |
| DK2723764T3 (en) | 2018-03-12 |
| BR112013032451A2 (pt) | 2016-11-22 |
| JP2014525735A (ja) | 2014-10-02 |
| EP2723764A2 (en) | 2014-04-30 |
| AU2012273987A1 (en) | 2014-01-30 |
| HUE036982T2 (hu) | 2018-08-28 |
| EP2723764B1 (en) | 2017-12-27 |
| CN107857810A (zh) | 2018-03-30 |
| EP4282882A3 (en) | 2024-03-06 |
| PT2723764T (pt) | 2018-03-09 |
| PL2723764T3 (pl) | 2018-05-30 |
| CN104053667B (zh) | 2017-09-15 |
| EP4282882A2 (en) | 2023-11-29 |