SG11202001226PA - Method for identifying positive allosteric modulators for odorant receptors - Google Patents
Method for identifying positive allosteric modulators for odorant receptorsInfo
- Publication number
- SG11202001226PA SG11202001226PA SG11202001226PA SG11202001226PA SG11202001226PA SG 11202001226P A SG11202001226P A SG 11202001226PA SG 11202001226P A SG11202001226P A SG 11202001226PA SG 11202001226P A SG11202001226P A SG 11202001226PA SG 11202001226P A SG11202001226P A SG 11202001226PA
- Authority
- SG
- Singapore
- Prior art keywords
- positive allosteric
- allosteric modulators
- odorant receptors
- identifying positive
- identifying
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762609017P | 2017-12-21 | 2017-12-21 | |
| US201762609004P | 2017-12-21 | 2017-12-21 | |
| EP18157690 | 2018-02-20 | ||
| EP18166887 | 2018-04-11 | ||
| US201862781796P | 2018-12-19 | 2018-12-19 | |
| PCT/EP2018/086388 WO2019122236A1 (en) | 2017-12-21 | 2018-12-20 | Method for identifying positive allosteric modulators for odorant receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202001226PA true SG11202001226PA (en) | 2020-03-30 |
Family
ID=64665102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202001226PA SG11202001226PA (en) | 2017-12-21 | 2018-12-20 | Method for identifying positive allosteric modulators for odorant receptors |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11921105B2 (en) |
| EP (1) | EP3658236A1 (en) |
| JP (2) | JP7343488B2 (en) |
| CN (1) | CN111050856A (en) |
| BR (1) | BR112020003239A2 (en) |
| SG (1) | SG11202001226PA (en) |
| WO (1) | WO2019122236A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3853328A2 (en) | 2018-12-19 | 2021-07-28 | Firmenich SA | Use of volatile compounds to modulate the perception of floral muguet |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2710825A (en) | 1954-04-16 | 1955-06-14 | Fmc Corp | Perfume composition |
| FR1364620A (en) | 1963-03-15 | 1964-06-26 | Rhone Poulenc Sa | Aldehyde p. isobutyldihydrocinnamic |
| BE672280A (en) | 1964-11-13 | 1966-05-12 | ||
| GB1528528A (en) | 1976-08-09 | 1978-10-11 | Shell Int Research | Cyclohexane derivatives |
| DE69018685T2 (en) | 1989-04-12 | 1995-08-17 | Firmenich & Cie | Aromatic aldehydes, their derivatives and their use as constituents in fragrances, herbicides and fungicides. |
| WO1994027946A1 (en) | 1993-05-26 | 1994-12-08 | Firmenich S.A. | Novel aromatic compounds and their use in perfume products |
| DE69516036T2 (en) | 1994-05-31 | 2000-12-21 | Firmenich & Cie | Aromatic compounds and their use in perfumery |
| EP1029845A1 (en) | 1999-02-15 | 2000-08-23 | Quest International B.V. | 2-(4-Tert-pentylcyclohexyl)acetaldehyde and its use as fragrance compound |
| DE60013353T2 (en) | 1999-05-19 | 2005-09-08 | Firmenich S.A. | Use of substituted acetaldehydes having a cyclic substituent as perfume ingredients |
| DE10026004A1 (en) | 2000-05-25 | 2001-11-29 | Cognis Deutschland Gmbh | 3,3-Dimethylcyclohexane derivatives |
| EP1529770B1 (en) | 2003-11-06 | 2011-08-17 | Firmenich SA | Aldehyde as perfuming or flavoring ingredient |
| GB0622037D0 (en) | 2006-11-04 | 2006-12-13 | Quest Int Serv Bv | Novel fragrance compounds |
| MX2009006094A (en) | 2006-12-08 | 2009-08-25 | Mane Fils V | Use of campholenic derivatives as fragrant ingredients in perfumery and flavouring. |
| US7511001B2 (en) | 2007-07-31 | 2009-03-31 | International Flavors & Fragrances Inc. | Substituted cyclohexyl propanal compounds and their use in perfume compositions |
| NZ594635A (en) | 2009-02-02 | 2012-12-21 | Chromocell Corp | Methods for assaying and isolating cell lines which stably expressed a sweet/bitter/umami taste receptor |
| WO2010091969A1 (en) | 2009-02-13 | 2010-08-19 | Basf Se | Lily of the valley-type fragrance compositions |
| US20100248390A1 (en) * | 2009-03-02 | 2010-09-30 | Duke University | Compositions and methods for identifying ligands of odorant receptors |
| WO2011029743A1 (en) | 2009-09-09 | 2011-03-17 | Basf Se | Lily of the valley-type fragrance compositions comprising 2,5,7,7-tetramethyloctanal |
| US8188023B2 (en) | 2009-11-16 | 2012-05-29 | International Flavors & Fragrances Inc. | 4-alkyl cyclohexanepropanal compounds and their use in perfume compositions |
| US20110118170A1 (en) | 2009-11-16 | 2011-05-19 | Levorse Jr Anthony T | Novel 4-alkyl 1-(3-methoxy-2-propen-1-yl) benzene compounds and their use in perfume compositions |
| US20110217257A1 (en) | 2009-11-16 | 2011-09-08 | Belko Robert P | Novel 4-alkyl cyclohexanepropanal compounds and their use in perfume compositions |
| US7834219B1 (en) | 2009-11-16 | 2010-11-16 | International Flavors & Fragrances Inc. | 4-alkyl cyclohexanepropanal compounds and their use in perfume compositions |
| US20110177964A1 (en) * | 2009-12-03 | 2011-07-21 | The Trustees Of Princeton University | Chemosensory arrays |
| ES2662372T3 (en) * | 2011-06-21 | 2018-04-06 | Vib Vzw | Binding domains directed against GPCR complexes: G protein and uses derived therefrom |
| EP2578671B1 (en) | 2011-10-07 | 2015-12-30 | Symrise AG | Aromatic substances with lily of the valley note |
| EP2594626B1 (en) | 2011-11-18 | 2014-06-25 | Symrise AG | Use of oxyacetaldehyde as lily of the valley fragrance |
| US9000226B2 (en) | 2012-02-09 | 2015-04-07 | Firmenich Sa | Aldehydes as perfuming ingredients |
| GB201308236D0 (en) | 2013-05-08 | 2013-06-12 | Givaudan Sa | Improvements in or relating to organic compounds |
| GB201308248D0 (en) | 2013-05-08 | 2013-06-12 | Givaudan Sa | Improvements in or relating to organic compounds |
| GB2515128B (en) | 2013-06-10 | 2015-05-27 | Givaudan Sa | Improvements in or relating to organic compounds |
| CN105339509A (en) | 2013-06-29 | 2016-02-17 | 弗门尼舍有限公司 | Methods of identifying, isolating and using odorant and aroma receptors |
| WO2015020158A1 (en) * | 2013-08-09 | 2015-02-12 | 国立大学法人東京大学 | Method for screening for musk perfume |
| WO2015095062A2 (en) * | 2013-12-16 | 2015-06-25 | Monell Chemical Senses Center | Methods of identifying modulators of olfactory receptors |
| GB2528467A (en) | 2014-07-22 | 2016-01-27 | Givaudan Sa | Organic compounds |
| JP2017528120A (en) * | 2014-08-26 | 2017-09-28 | ユニベルシテ ドゥ ジュネーブ | Methods and uses for identifying receptors for ligands |
| GB2529901A (en) | 2014-09-08 | 2016-03-09 | Givaudan Sa | Organic compounds |
| CN107074712B (en) | 2014-11-10 | 2021-06-29 | 奇华顿股份有限公司 | Improvements in or relating to organic compounds |
| WO2016074118A1 (en) | 2014-11-10 | 2016-05-19 | Givaudan Sa | Improvements in or relating to organic compounds |
| WO2016074719A1 (en) | 2014-11-12 | 2016-05-19 | Givaudan Sa | Improvements in or relating to organic compounds |
| EP3307770B1 (en) * | 2015-06-10 | 2020-05-27 | Firmenich SA | Method of identifying musk compounds |
| JP6961494B2 (en) | 2015-06-10 | 2021-11-05 | フイルメニツヒ ソシエテ アノニムFirmenich Sa | Cell lines for screening odorant and aroma receptors |
| BR112017028575B1 (en) | 2015-07-14 | 2022-05-31 | Firmenich Sa | Compost that has a muguey odor |
| US20180297922A1 (en) | 2015-10-12 | 2018-10-18 | International Flavors & Fragrances Inc. | Novel octahydroindenyl propanal compounds |
| EP3386319A4 (en) * | 2015-12-11 | 2019-10-16 | Bedoukian Research, Inc. | Fragrance and flavor compositions containing isomeric alkadienals or isomeric alkadienenitriles |
| ES2850878T3 (en) | 2017-01-18 | 2021-09-01 | Firmenich & Cie | Composition with the aroma of thrush |
-
2018
- 2018-12-20 US US16/639,307 patent/US11921105B2/en active Active
- 2018-12-20 WO PCT/EP2018/086388 patent/WO2019122236A1/en unknown
- 2018-12-20 JP JP2020518714A patent/JP7343488B2/en active Active
- 2018-12-20 EP EP18819260.3A patent/EP3658236A1/en active Pending
- 2018-12-20 SG SG11202001226PA patent/SG11202001226PA/en unknown
- 2018-12-20 BR BR112020003239-5A patent/BR112020003239A2/en unknown
- 2018-12-20 CN CN201880054532.XA patent/CN111050856A/en active Pending
-
2023
- 2023-08-31 JP JP2023141451A patent/JP2023164913A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2021508030A (en) | 2021-02-25 |
| JP7343488B2 (en) | 2023-09-12 |
| CN111050856A (en) | 2020-04-21 |
| WO2019122236A1 (en) | 2019-06-27 |
| BR112020003239A2 (en) | 2020-08-18 |
| US20200408738A1 (en) | 2020-12-31 |
| EP3658236A1 (en) | 2020-06-03 |
| US11921105B2 (en) | 2024-03-05 |
| JP2023164913A (en) | 2023-11-14 |
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