NO20092605L - Fremstilling av oftalmisk innretning basert pa fotoindusert trinnvekst polymerisasjon - Google Patents
Fremstilling av oftalmisk innretning basert pa fotoindusert trinnvekst polymerisasjonInfo
- Publication number
- NO20092605L NO20092605L NO20092605A NO20092605A NO20092605L NO 20092605 L NO20092605 L NO 20092605L NO 20092605 A NO20092605 A NO 20092605A NO 20092605 A NO20092605 A NO 20092605A NO 20092605 L NO20092605 L NO 20092605L
- Authority
- NO
- Norway
- Prior art keywords
- groups
- group
- divalent
- prepolymer
- alkyl
- Prior art date
Links
- 238000007155 step growth polymerization reaction Methods 0.000 title claims abstract description 35
- 238000002360 preparation method Methods 0.000 title abstract description 14
- 239000000203 mixture Substances 0.000 claims abstract description 136
- 238000000034 method Methods 0.000 claims abstract description 66
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- 239000000017 hydrogel Substances 0.000 claims abstract description 44
- -1 siloxane units Chemical group 0.000 claims description 115
- 239000000178 monomer Substances 0.000 claims description 99
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- 125000002348 vinylic group Chemical group 0.000 claims description 49
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- 238000004519 manufacturing process Methods 0.000 claims description 33
- 239000003431 cross linking reagent Substances 0.000 claims description 32
- 239000001257 hydrogen Substances 0.000 claims description 31
- 229910052739 hydrogen Inorganic materials 0.000 claims description 31
- 125000000524 functional group Chemical group 0.000 claims description 28
- 125000003396 thiol group Chemical group [H]S* 0.000 claims description 28
- 230000005855 radiation Effects 0.000 claims description 22
- 150000001336 alkenes Chemical class 0.000 claims description 19
- 125000000217 alkyl group Chemical group 0.000 claims description 19
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 18
- 150000002431 hydrogen Chemical class 0.000 claims description 18
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- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 13
- 125000003647 acryloyl group Chemical group O=C([*])C([H])=C([H])[H] 0.000 claims description 12
- 150000001875 compounds Chemical class 0.000 claims description 12
- WBYWAXJHAXSJNI-UHFFFAOYSA-N cinnamic acid group Chemical group C(C=CC1=CC=CC=C1)(=O)O WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 claims description 11
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 11
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims description 10
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 9
- 239000002253 acid Substances 0.000 claims description 8
- 125000003277 amino group Chemical group 0.000 claims description 8
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 8
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 7
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 239000004593 Epoxy Substances 0.000 claims description 6
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims description 6
- 239000004202 carbamide Substances 0.000 claims description 5
- 229920002396 Polyurea Polymers 0.000 claims description 4
- 125000003418 alkyl amino alkoxy group Chemical group 0.000 claims description 4
- 238000007334 copolymerization reaction Methods 0.000 claims description 4
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- 125000002431 aminoalkoxy group Chemical group 0.000 claims description 3
- 125000004122 cyclic group Chemical group 0.000 claims description 3
- 125000005113 hydroxyalkoxy group Chemical group 0.000 claims description 3
- 238000001029 thermal curing Methods 0.000 claims description 3
- 125000005376 alkyl siloxane group Chemical group 0.000 claims description 2
- 125000005111 carboxyalkoxy group Chemical group 0.000 claims description 2
- 150000004985 diamines Chemical class 0.000 claims description 2
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- 229920002635 polyurethane Polymers 0.000 claims description 2
- 239000004814 polyurethane Substances 0.000 claims description 2
- 125000004181 carboxyalkyl group Chemical group 0.000 claims 5
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 4
- 125000005055 alkyl alkoxy group Chemical group 0.000 claims 3
- 125000000278 alkyl amino alkyl group Chemical group 0.000 claims 3
- 238000001723 curing Methods 0.000 abstract description 17
- 102000007469 Actins Human genes 0.000 abstract 1
- 108010085238 Actins Proteins 0.000 abstract 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 131
- 239000000243 solution Substances 0.000 description 96
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- 239000000839 emulsion Substances 0.000 description 49
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 48
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- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 32
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- 239000008367 deionised water Substances 0.000 description 26
- 229910021641 deionized water Inorganic materials 0.000 description 26
- 229910052757 nitrogen Inorganic materials 0.000 description 26
- 238000003756 stirring Methods 0.000 description 24
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- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 20
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 18
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 18
- 239000011541 reaction mixture Substances 0.000 description 18
- OMIGHNLMNHATMP-UHFFFAOYSA-N 2-hydroxyethyl prop-2-enoate Chemical compound OCCOC(=O)C=C OMIGHNLMNHATMP-UHFFFAOYSA-N 0.000 description 17
- 229920000570 polyether Polymers 0.000 description 17
- 238000010992 reflux Methods 0.000 description 17
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 16
- 239000000126 substance Substances 0.000 description 16
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 16
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 15
- 125000004432 carbon atom Chemical group C* 0.000 description 14
- 229910052760 oxygen Inorganic materials 0.000 description 14
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- 239000000049 pigment Substances 0.000 description 14
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 13
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- 239000003999 initiator Substances 0.000 description 13
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- 239000012466 permeate Substances 0.000 description 13
- OZAIFHULBGXAKX-UHFFFAOYSA-N 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile Chemical compound N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 description 12
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 12
- 230000000845 anti-microbial effect Effects 0.000 description 12
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- 239000004205 dimethyl polysiloxane Substances 0.000 description 12
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- 238000000605 extraction Methods 0.000 description 11
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- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 10
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- 150000003254 radicals Chemical class 0.000 description 10
- OGMADIBCHLQMIP-UHFFFAOYSA-N 2-aminoethanethiol;hydron;chloride Chemical compound Cl.NCCS OGMADIBCHLQMIP-UHFFFAOYSA-N 0.000 description 9
- 239000004971 Cross linker Substances 0.000 description 9
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- 239000012986 chain transfer agent Substances 0.000 description 9
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- HFBMWMNUJJDEQZ-UHFFFAOYSA-N acryloyl chloride Chemical compound ClC(=O)C=C HFBMWMNUJJDEQZ-UHFFFAOYSA-N 0.000 description 8
- 238000001816 cooling Methods 0.000 description 8
- 238000004128 high performance liquid chromatography Methods 0.000 description 8
- 229920000831 ionic polymer Polymers 0.000 description 8
- 229940088644 n,n-dimethylacrylamide Drugs 0.000 description 8
- YLGYACDQVQQZSW-UHFFFAOYSA-N n,n-dimethylprop-2-enamide Chemical compound CN(C)C(=O)C=C YLGYACDQVQQZSW-UHFFFAOYSA-N 0.000 description 8
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- 239000000047 product Substances 0.000 description 8
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- 150000003573 thiols Chemical class 0.000 description 8
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- 238000006243 chemical reaction Methods 0.000 description 7
- 230000000704 physical effect Effects 0.000 description 7
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 6
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 description 6
- CGWGNMXPEVGWGB-UHFFFAOYSA-N 2-hydroxy-1-[4-(2-hydroxyethyl)phenyl]-2-methylpropan-1-one Chemical compound CC(C)(O)C(=O)C1=CC=C(CCO)C=C1 CGWGNMXPEVGWGB-UHFFFAOYSA-N 0.000 description 6
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- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 5
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 5
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- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 description 5
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- FMQPBWHSNCRVQJ-UHFFFAOYSA-N 1,1,1,3,3,3-hexafluoropropan-2-yl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OC(C(F)(F)F)C(F)(F)F FMQPBWHSNCRVQJ-UHFFFAOYSA-N 0.000 description 4
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- ZAZJGBCGMUKZEL-UHFFFAOYSA-N 2-[ethyl(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctylsulfonyl)amino]ethyl prop-2-enoate Chemical compound C=CC(=O)OCCN(CC)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F ZAZJGBCGMUKZEL-UHFFFAOYSA-N 0.000 description 4
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- 150000002632 lipids Chemical class 0.000 description 1
- RVGLGHVJXCETIO-UHFFFAOYSA-N lodoxamide Chemical compound OC(=O)C(=O)NC1=CC(C#N)=CC(NC(=O)C(O)=O)=C1Cl RVGLGHVJXCETIO-UHFFFAOYSA-N 0.000 description 1
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- HNEGQIOMVPPMNR-NSCUHMNNSA-N mesaconic acid Chemical compound OC(=O)C(/C)=C/C(O)=O HNEGQIOMVPPMNR-NSCUHMNNSA-N 0.000 description 1
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- 150000003222 pyridines Chemical class 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 description 1
- 229910000077 silane Inorganic materials 0.000 description 1
- 125000004469 siloxy group Chemical group [SiH3]O* 0.000 description 1
- FVEFRICMTUKAML-UHFFFAOYSA-M sodium tetradecyl sulfate Chemical compound [Na+].CCCCC(CC)CCC(CC(C)C)OS([O-])(=O)=O FVEFRICMTUKAML-UHFFFAOYSA-M 0.000 description 1
- MNCGMVDMOKPCSQ-UHFFFAOYSA-M sodium;2-phenylethenesulfonate Chemical compound [Na+].[O-]S(=O)(=O)C=CC1=CC=CC=C1 MNCGMVDMOKPCSQ-UHFFFAOYSA-M 0.000 description 1
- BWYYYTVSBPRQCN-UHFFFAOYSA-M sodium;ethenesulfonate Chemical compound [Na+].[O-]S(=O)(=O)C=C BWYYYTVSBPRQCN-UHFFFAOYSA-M 0.000 description 1
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- RVEZZJVBDQCTEF-UHFFFAOYSA-N sulfenic acid Chemical class SO RVEZZJVBDQCTEF-UHFFFAOYSA-N 0.000 description 1
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- 238000012360 testing method Methods 0.000 description 1
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- 125000004149 thio group Chemical group *S* 0.000 description 1
- RSPCKAHMRANGJZ-UHFFFAOYSA-N thiohydroxylamine Chemical class SN RSPCKAHMRANGJZ-UHFFFAOYSA-N 0.000 description 1
- 229910052718 tin Inorganic materials 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N titanium dioxide Inorganic materials O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- 235000010215 titanium dioxide Nutrition 0.000 description 1
- 235000019756 total sulphur amino acid Nutrition 0.000 description 1
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- ILWRPSCZWQJDMK-UHFFFAOYSA-N triethylazanium;chloride Chemical compound Cl.CCN(CC)CC ILWRPSCZWQJDMK-UHFFFAOYSA-N 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- UHUUYVZLXJHWDV-UHFFFAOYSA-N trimethyl(methylsilyloxy)silane Chemical compound C[SiH2]O[Si](C)(C)C UHUUYVZLXJHWDV-UHFFFAOYSA-N 0.000 description 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00009—Production of simple or compound lenses
- B29D11/00038—Production of contact lenses
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F275/00—Macromolecular compounds obtained by polymerising monomers on to polymers of monomers containing phosphorus, selenium, tellurium or a metal as defined in group C08F30/00
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
- G02B1/041—Lenses
- G02B1/043—Contact lenses
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US86981206P | 2006-12-13 | 2006-12-13 | |
PCT/US2007/087147 WO2008076729A1 (en) | 2006-12-13 | 2007-12-12 | Production of ophthalmic devices based on photo-induced step growth polymerization |
Publications (1)
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NO20092605L true NO20092605L (no) | 2009-09-09 |
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NO20092605A NO20092605L (no) | 2006-12-13 | 2009-07-08 | Fremstilling av oftalmisk innretning basert pa fotoindusert trinnvekst polymerisasjon |
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US (3) | US8003710B2 (es) |
EP (1) | EP2092376B1 (es) |
JP (1) | JP5455642B2 (es) |
CN (2) | CN102662201A (es) |
AR (1) | AR064286A1 (es) |
AU (1) | AU2007334064B2 (es) |
BR (1) | BRPI0720296A2 (es) |
CA (2) | CA2671960C (es) |
DK (1) | DK2092376T3 (es) |
ES (1) | ES2396988T3 (es) |
MX (1) | MX2009005937A (es) |
NO (1) | NO20092605L (es) |
PL (1) | PL2092376T3 (es) |
PT (1) | PT2092376E (es) |
TW (1) | TWI411831B (es) |
WO (1) | WO2008076729A1 (es) |
ZA (1) | ZA200902299B (es) |
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AR064286A1 (es) | 2006-12-13 | 2009-03-25 | Quiceno Gomez Alexandra Lorena | Produccion de dispositivos oftalmicos basados en la polimerizacion por crecimiento escalonado fotoinducida |
US20080203592A1 (en) * | 2007-02-26 | 2008-08-28 | Yongxing Qiu | Method for imparting hydrogel contact lenses with desired properties |
EP2126614B1 (en) | 2007-03-22 | 2019-04-24 | Novartis AG | Silicone-containing prepolymers with hydrophilic polymeric chains |
US8044111B2 (en) | 2007-11-30 | 2011-10-25 | Novartis Ag | Actinically-crosslinkable silicone-containing block copolymers |
WO2009085902A1 (en) | 2007-12-20 | 2009-07-09 | Novartis Ag | Method for making contact lenses |
US20100280147A1 (en) * | 2008-02-15 | 2010-11-04 | Laura Hartmann | High refractive index interpenetrating networks for ophthalmic applications |
JP5721267B2 (ja) * | 2008-07-21 | 2015-05-20 | ノバルティス アーゲー | シリコーンハイドロゲルコンタクトレンズを製造する方法 |
CA2730506A1 (en) | 2008-07-21 | 2010-01-28 | Novartis Ag | Silicone-containing polymeric materials with hydrolyzable groups |
CN102209745B (zh) * | 2008-11-13 | 2013-11-27 | 诺华股份有限公司 | 含末端亲水聚合物链的聚硅氧烷共聚物 |
TWI506333B (zh) * | 2008-12-05 | 2015-11-01 | Novartis Ag | 用以傳遞疏水性舒適劑之眼用裝置及其製造方法 |
WO2010071691A1 (en) * | 2008-12-18 | 2010-06-24 | Novartis Ag | Method for making silicone hydrogel contact lenses |
RU2544540C2 (ru) | 2008-12-30 | 2015-03-20 | Новартис Аг | Поглощающие уф-излучение трифункциональные соединения и их применение |
WO2010135481A1 (en) | 2009-05-22 | 2010-11-25 | Novartis Ag | Actinically-crosslinkable siloxane-containing copolymers |
HUE027398T2 (en) * | 2009-05-22 | 2016-10-28 | Novartis Ag | Proteolymers containing siloxane having actinically crosslinkable |
US8470948B2 (en) * | 2009-08-28 | 2013-06-25 | Florida State University Research Foundation, Inc. | High refractive index polymers |
MX2012003140A (es) | 2009-09-15 | 2012-04-20 | Novartis Ag | Prepolimeros adecuados para hacer lentes de contacto que absorben la radiacion ultravioleta. |
TWI490260B (zh) * | 2009-09-22 | 2015-07-01 | Coopervision Int Holding Co Lp | 用於眼科應用及方法之可濕性水凝膠材料 |
TWI407980B (zh) * | 2009-10-15 | 2013-09-11 | Univ Nat Taiwan | 具有奈米二氧化鈦粒子之光起始高分子水晶體材料及其製備方式 |
CN102639636A (zh) * | 2009-12-07 | 2012-08-15 | 诺瓦提斯公司 | 用于增加接触透镜的离子传输率的方法 |
TWI483996B (zh) | 2009-12-08 | 2015-05-11 | Novartis Ag | 具有共價貼合塗層之聚矽氧水凝膠鏡片 |
WO2011075377A1 (en) * | 2009-12-14 | 2011-06-23 | Novartis Ag | Methods for making silicone hydrogel lenses from water-based lens formulations |
US8946367B2 (en) | 2010-06-22 | 2015-02-03 | Isp Investments Inc. | Polymerizable carbamate and thiocarbamate compounds, polymers derived from them, and compositions thereof |
RU2569365C2 (ru) | 2010-07-30 | 2015-11-27 | Новартис Аг | Способ изготовления поглощающих уф-излучение офтальмологических линз |
RU2540655C2 (ru) | 2010-07-30 | 2015-02-10 | Новартис Аг | Силиконовые гидрогелевые линзы с обогащенными водой поверхностями |
NZ604337A (en) | 2010-07-30 | 2014-05-30 | Novartis Ag | Amphiphilic polysiloxane prepolymers and uses thereof |
NZ606787A (en) | 2010-10-06 | 2014-11-28 | Novartis Ag | Water-processable silicone-containing prepolymers and uses thereof |
JP5784131B2 (ja) | 2010-10-06 | 2015-09-24 | ノバルティス アーゲー | ペンダント親水性基を持つ重合しうる鎖延長ポリシロキサン |
WO2012047964A1 (en) | 2010-10-06 | 2012-04-12 | Novartis Ag | Chain-extended polysiloxane crosslinkers with dangling hydrophilic polymer chains |
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HUE030629T2 (en) | 2010-12-13 | 2017-05-29 | Novartis Ag | Functionally modified ophthalmic lenses and method for their preparation |
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US8618187B2 (en) * | 2011-04-01 | 2013-12-31 | Novartis Ag | Composition for forming a contact lens |
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HUE029018T2 (en) | 2011-10-12 | 2017-02-28 | Novartis Ag | A method for producing UV absorbing contact lenses by coating |
US9395468B2 (en) | 2012-08-27 | 2016-07-19 | Ocular Dynamics, Llc | Contact lens with a hydrophilic layer |
US20140066537A1 (en) * | 2012-09-06 | 2014-03-06 | Universite De Liege | Organic compositions for repeatedly adjustable optical elements and such elements |
US8937133B2 (en) | 2012-09-25 | 2015-01-20 | National Chiao Tung University | Dissoluble PDMS-modified p(HEMA-MAA) amphiphilic copolymer and method for fabricating the same |
US9103965B2 (en) | 2012-12-14 | 2015-08-11 | Novartis Ag | Amphiphilic siloxane-containing vinylic monomers and uses thereof |
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US7371804B2 (en) * | 2004-09-07 | 2008-05-13 | Ophthonix, Inc. | Monomers and polymers for optical elements |
US7247692B2 (en) * | 2004-09-30 | 2007-07-24 | Johnson & Johnson Vision Care, Inc. | Biomedical devices containing amphiphilic block copolymers |
BRPI0607430B8 (pt) * | 2005-02-14 | 2021-06-22 | Johnson & Johnson Vision Care | dispositivo oftálmico confortável e métodos de sua produção |
US7858000B2 (en) * | 2006-06-08 | 2010-12-28 | Novartis Ag | Method of making silicone hydrogel contact lenses |
DK2038310T3 (da) * | 2006-07-12 | 2010-09-27 | Novartis Ag | Aktinisk tværbindelige copolymerer til fremstilling af kontaktlinser |
AR064286A1 (es) * | 2006-12-13 | 2009-03-25 | Quiceno Gomez Alexandra Lorena | Produccion de dispositivos oftalmicos basados en la polimerizacion por crecimiento escalonado fotoinducida |
-
2007
- 2007-12-11 AR ARP070105544 patent/AR064286A1/es not_active Application Discontinuation
- 2007-12-12 MX MX2009005937A patent/MX2009005937A/es active IP Right Grant
- 2007-12-12 JP JP2009541540A patent/JP5455642B2/ja not_active Expired - Fee Related
- 2007-12-12 EP EP20070855080 patent/EP2092376B1/en not_active Not-in-force
- 2007-12-12 TW TW96147413A patent/TWI411831B/zh not_active IP Right Cessation
- 2007-12-12 AU AU2007334064A patent/AU2007334064B2/en not_active Ceased
- 2007-12-12 CA CA2671960A patent/CA2671960C/en not_active Expired - Fee Related
- 2007-12-12 WO PCT/US2007/087147 patent/WO2008076729A1/en active Application Filing
- 2007-12-12 BR BRPI0720296-2A2A patent/BRPI0720296A2/pt not_active IP Right Cessation
- 2007-12-12 PT PT78550803T patent/PT2092376E/pt unknown
- 2007-12-12 ES ES07855080T patent/ES2396988T3/es active Active
- 2007-12-12 US US12/001,562 patent/US8003710B2/en active Active
- 2007-12-12 DK DK07855080T patent/DK2092376T3/da active
- 2007-12-12 CA CA 2868863 patent/CA2868863A1/en active Pending
- 2007-12-12 PL PL07855080T patent/PL2092376T3/pl unknown
- 2007-12-12 CN CN2012101529795A patent/CN102662201A/zh active Pending
- 2007-12-12 CN CN2007800463251A patent/CN101558329B/zh not_active Expired - Fee Related
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2009
- 2009-04-02 ZA ZA200902299A patent/ZA200902299B/xx unknown
- 2009-07-08 NO NO20092605A patent/NO20092605L/no not_active Application Discontinuation
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2011
- 2011-07-14 US US13/182,969 patent/US8357771B2/en not_active Expired - Fee Related
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Also Published As
Publication number | Publication date |
---|---|
CN101558329A (zh) | 2009-10-14 |
US8609745B2 (en) | 2013-12-17 |
CA2671960A1 (en) | 2008-06-26 |
WO2008076729A1 (en) | 2008-06-26 |
US8003710B2 (en) | 2011-08-23 |
TW200848833A (en) | 2008-12-16 |
JP2010513954A (ja) | 2010-04-30 |
AU2007334064B2 (en) | 2010-12-23 |
MX2009005937A (es) | 2009-06-17 |
PL2092376T3 (pl) | 2013-03-29 |
JP5455642B2 (ja) | 2014-03-26 |
CA2671960C (en) | 2015-10-06 |
BRPI0720296A2 (pt) | 2014-02-04 |
US20130106007A1 (en) | 2013-05-02 |
CN101558329B (zh) | 2012-07-04 |
US20110269869A1 (en) | 2011-11-03 |
DK2092376T3 (da) | 2013-02-04 |
PT2092376E (pt) | 2012-12-19 |
EP2092376B1 (en) | 2012-10-17 |
AU2007334064A1 (en) | 2008-06-26 |
CN102662201A (zh) | 2012-09-12 |
EP2092376A1 (en) | 2009-08-26 |
ES2396988T3 (es) | 2013-03-01 |
US8357771B2 (en) | 2013-01-22 |
US20080143958A1 (en) | 2008-06-19 |
ZA200902299B (en) | 2010-04-28 |
TWI411831B (zh) | 2013-10-11 |
AR064286A1 (es) | 2009-03-25 |
CA2868863A1 (en) | 2008-06-26 |
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