NO20091980L - Fremgangsmåte for syntese av N-[3-[(2-metoksyfenyl)sulfanyl]-2-metylpropyl]-3,4-dihydro-2H-1,5-benzoksatiepin-3-amin - Google Patents

Fremgangsmåte for syntese av N-[3-[(2-metoksyfenyl)sulfanyl]-2-metylpropyl]-3,4-dihydro-2H-1,5-benzoksatiepin-3-amin

Info

Publication number
NO20091980L
NO20091980L NO20091980A NO20091980A NO20091980L NO 20091980 L NO20091980 L NO 20091980L NO 20091980 A NO20091980 A NO 20091980A NO 20091980 A NO20091980 A NO 20091980A NO 20091980 L NO20091980 L NO 20091980L
Authority
NO
Norway
Prior art keywords
benzoxatepin
sulfanyl
methylpropyl
methoxyphenyl
dihydro
Prior art date
Application number
NO20091980A
Other languages
English (en)
Inventor
Bernard Vacher
Yves Brunel
Jean-Louis Maurel
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of NO20091980L publication Critical patent/NO20091980L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/18Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/20Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO20091980A 2006-11-08 2009-05-22 Fremgangsmåte for syntese av N-[3-[(2-metoksyfenyl)sulfanyl]-2-metylpropyl]-3,4-dihydro-2H-1,5-benzoksatiepin-3-amin NO20091980L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0609815A FR2908132B1 (fr) 2006-11-08 2006-11-08 Procede de synthese du n-[3-[(2-methoxyphenyl)sulfanyl]-2- methylpropyl]-3,4-dihydro-2h-1,5-benzoxathiepin-3-amine
PCT/FR2007/001831 WO2008068403A2 (fr) 2006-11-08 2007-11-06 Procede de synthese du n- [3- [ (2-methoxyphenyl) sulfanyl] -2- methylpropyl] -3,4-dihydro-2h-1,5-benzoxathiepin-3-amine

Publications (1)

Publication Number Publication Date
NO20091980L true NO20091980L (no) 2009-06-08

Family

ID=38066470

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091980A NO20091980L (no) 2006-11-08 2009-05-22 Fremgangsmåte for syntese av N-[3-[(2-metoksyfenyl)sulfanyl]-2-metylpropyl]-3,4-dihydro-2H-1,5-benzoksatiepin-3-amin

Country Status (27)

Country Link
US (1) US7982054B2 (no)
EP (1) EP2089374B1 (no)
JP (1) JP5180965B2 (no)
KR (1) KR101390486B1 (no)
CN (1) CN101535287B (no)
AR (1) AR063592A1 (no)
AT (1) ATE476429T1 (no)
AU (1) AU2007330711B2 (no)
BR (1) BRPI0718702A2 (no)
CA (1) CA2668951C (no)
DE (1) DE602007008284D1 (no)
ES (1) ES2350324T3 (no)
FR (1) FR2908132B1 (no)
HK (1) HK1131970A1 (no)
IL (1) IL198528A (no)
MA (1) MA30800B1 (no)
MX (1) MX2009003957A (no)
NO (1) NO20091980L (no)
NZ (1) NZ576442A (no)
PL (1) PL2089374T3 (no)
PT (1) PT2089374E (no)
RU (1) RU2414464C9 (no)
TN (1) TN2009000176A1 (no)
TW (1) TWI397527B (no)
UA (1) UA94632C2 (no)
WO (1) WO2008068403A2 (no)
ZA (1) ZA200902732B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2979823B1 (fr) * 2011-09-13 2013-09-27 Pf Medicament Utilisation du 3-(r)-[3-(2-methoxyphenylthio)-2-(s)-methyl-propyl]amino-3,4-dihydro-2h-1,5-benzoxathiepine pour le traitement du cancer et en particulier pour la prevention et/ou le traitement des metastases cancereuses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2868779B1 (fr) * 2004-04-09 2008-08-22 Pierre Fabre Medicament Sa Procede de synthese et intermediaires de benzoxathiepines

Also Published As

Publication number Publication date
PL2089374T3 (pl) 2011-01-31
AR063592A1 (es) 2009-02-04
ES2350324T3 (es) 2011-01-21
CN101535287A (zh) 2009-09-16
EP2089374B1 (fr) 2010-08-04
BRPI0718702A2 (pt) 2014-01-07
WO2008068403A3 (fr) 2008-11-27
RU2009121560A (ru) 2010-12-20
ZA200902732B (en) 2010-02-24
EP2089374A2 (fr) 2009-08-19
MX2009003957A (es) 2009-04-28
TWI397527B (zh) 2013-06-01
UA94632C2 (en) 2011-05-25
PT2089374E (pt) 2010-11-04
IL198528A (en) 2012-12-31
KR101390486B1 (ko) 2014-05-19
IL198528A0 (en) 2010-02-17
JP5180965B2 (ja) 2013-04-10
ATE476429T1 (de) 2010-08-15
JP2010509296A (ja) 2010-03-25
NZ576442A (en) 2012-03-30
CN101535287B (zh) 2013-02-27
WO2008068403A2 (fr) 2008-06-12
FR2908132B1 (fr) 2008-12-19
US20090318709A1 (en) 2009-12-24
CA2668951C (fr) 2012-06-26
AU2007330711A1 (en) 2008-06-12
TN2009000176A1 (fr) 2010-10-18
RU2414464C9 (ru) 2011-11-10
HK1131970A1 (en) 2010-02-12
KR20090082463A (ko) 2009-07-30
MA30800B1 (fr) 2009-10-01
US7982054B2 (en) 2011-07-19
DE602007008284D1 (de) 2010-09-16
RU2414464C2 (ru) 2011-03-20
AU2007330711B2 (en) 2011-11-03
FR2908132A1 (fr) 2008-05-09
TW200835688A (en) 2008-09-01
CA2668951A1 (fr) 2008-06-12

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