NO20085418L - Langvarig, 24-timers tarmadministrering av levodopa/karbidopa - Google Patents

Langvarig, 24-timers tarmadministrering av levodopa/karbidopa

Info

Publication number
NO20085418L
NO20085418L NO20085418A NO20085418A NO20085418L NO 20085418 L NO20085418 L NO 20085418L NO 20085418 A NO20085418 A NO 20085418A NO 20085418 A NO20085418 A NO 20085418A NO 20085418 L NO20085418 L NO 20085418L
Authority
NO
Norway
Prior art keywords
levodopa
carbidopa
hour
term
long
Prior art date
Application number
NO20085418A
Other languages
English (en)
Inventor
Dag Nyholm
Stefan Asberg
Roger Bolsoey
Mikael Tutschke-Saettler
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of NO20085418L publication Critical patent/NO20085418L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Psychology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Sammendrag Fremgangsmåte for å behandle Parkinsons sykdom som omfatter tarmadministrering til en pasient med behov for det, av en farmasøytisk effektiv mengde av et preparat som omfatter levodopa og eventuelt karbidopa kontinuerlig over en periode på mer enn 16 timer.
NO20085418A 2006-05-31 2008-12-30 Langvarig, 24-timers tarmadministrering av levodopa/karbidopa NO20085418L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80988906P 2006-05-31 2006-05-31
PCT/EP2007/055275 WO2007138086A1 (en) 2006-05-31 2007-05-31 Long term 24 hour intestinal administration of levodopa/carbidopa

Publications (1)

Publication Number Publication Date
NO20085418L true NO20085418L (no) 2009-02-26

Family

ID=38434843

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20085418A NO20085418L (no) 2006-05-31 2008-12-30 Langvarig, 24-timers tarmadministrering av levodopa/karbidopa

Country Status (16)

Country Link
US (1) US20080051459A1 (no)
EP (1) EP2063865A1 (no)
JP (1) JP2009543761A (no)
KR (1) KR20090057349A (no)
CN (1) CN101636145B (no)
AU (1) AU2007267135B2 (no)
BR (1) BRPI0711882A2 (no)
CA (1) CA2653683A1 (no)
HK (1) HK1137931A1 (no)
IL (1) IL195599A0 (no)
MX (1) MX2008015339A (no)
NO (1) NO20085418L (no)
RU (1) RU2484815C2 (no)
UA (1) UA95954C2 (no)
WO (1) WO2007138086A1 (no)
ZA (1) ZA200810834B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2485947C2 (ru) 2008-02-06 2013-06-27 Вокхардт Рисерч Сентер Фармацевтические композиции энтакапона, леводопы и карбидопы с улучшенной биодоступностью
SG10201505101VA (en) * 2009-05-19 2015-07-30 Neuroderm Ltd Compositions For Continuous Administration Of Dopa Decarboxylase Inhibitors
JP5902705B2 (ja) * 2010-11-15 2016-04-13 ニューロダーム リミテッドNeuroderm Ltd L−ドーパ、ドーパデカルボキシラーゼ阻害剤、カテコール−o−メチルトランスフェラーゼ阻害剤、およびそれらのための組成物の継続的投与
EP2508174A1 (en) 2011-04-06 2012-10-10 Ljiljana Sovic Brkicic Pharmaceutical composition
EP2653179B1 (en) 2012-04-17 2019-07-10 Micrel Medical Devices S.A. System for calculating and administering a drug to a patient with Parkinson's disease
JP6257604B2 (ja) 2012-06-05 2018-01-10 ニューロダーム リミテッドNeuroderm Ltd アポモルヒネと有機酸とを含む組成物およびその使用
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
ES2967693T3 (es) 2014-03-13 2024-05-03 Neuroderm Ltd Composiciones del inhibidor de la dopa descarboxilasa
PT3188725T (pt) 2014-09-04 2021-01-27 Lobsor Pharmaceuticals Ab Composições farmacêuticas compreendendo levodopa, um inibidor de descarboxílase de dopamina e um inibidor de comt, e método de administração destes
TWI755257B (zh) 2014-10-21 2022-02-11 美商艾伯維有限公司 卡比多巴及左旋多巴之前藥及使用方法
MA41377A (fr) * 2015-01-20 2017-11-28 Abbvie Inc Gel intestinal de lévodopa et de carbidona et procédés d'utilisation
AU2016258179B2 (en) 2015-05-06 2021-07-01 Synagile Corporation Pharmaceutical suspensions containing drug particles, devices for their administration, and methods of their use
WO2017039525A1 (en) 2015-09-04 2017-03-09 Lobsor Pharmaceuticals Aktiebolag Method of treating a dopamine related disorder in a subject by administering levodopa, in combination with a dopamine decarboxylase inhibitor and a catechol-o-methyltransferase inhibitor
CN109715139A (zh) * 2016-07-20 2019-05-03 艾伯维公司 左旋多巴和卡比多巴肠凝胶以及使用方法
ES2895054T3 (es) 2016-08-18 2022-02-17 Ilko Ilac Sanayi Ve Ticaret Anonim Sirketi Fórmula de comprimido antiparkinson con perfil de disolución mejorado
EP3758754A1 (en) 2018-03-02 2021-01-06 Chiesi Farmaceutici S.p.A. A pharmaceutical formulation for intraduodenal administration comprising melevodopa and carbidopa
CN112261940B (zh) 2018-03-23 2024-02-27 劳波索尔制药有限公司 用于治疗神经退行性疾病的药物组合物的连续施用
CN111954523A (zh) * 2018-03-29 2020-11-17 艾维制药有限责任公司 左旋多巴分次剂量组合物及用途
US11389398B2 (en) 2019-05-14 2022-07-19 Clexio Biosciences Ltd. Gastroretentive treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
WO2023126945A1 (en) * 2022-01-03 2023-07-06 Neuroderm, Ltd. Methods and compositions for treating parkinson's disease

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9203594D0 (sv) * 1992-11-30 1992-11-30 Christer Nystroem Laekemedel i dispersa system
US6166081A (en) * 1997-10-09 2000-12-26 Kushnir; Moshe Methods and apparatus for treatment of Parkinson's disease
JP2004501190A (ja) * 2000-06-23 2004-01-15 テバ ファーマシューティカル インダストリーズ リミティド 治療薬の胃部保留および制御された放出のための急速膨張する組成物とその組成物を含む剤形
FR2829027A1 (fr) * 2001-08-29 2003-03-07 Aventis Pharma Sa Association avec un antagoniste du recepteur cb1, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement de la maladie de parkinson
US20060013875A1 (en) * 2002-05-29 2006-01-19 Impax Laboratories, Inc. Combination immediate release controlled release levodopa/carbidopa dosage forms
ITMI20030827A1 (it) * 2003-04-18 2004-10-19 Unihart Corp Composizione farmaceutica contenente l'associazione levodopa/carbidopa.
WO2005042101A1 (en) * 2003-10-20 2005-05-12 Teva Pharmaceutical Industries Ltd. Composition and dosage form for sustained effect of levodopa
WO2005121069A1 (en) * 2004-06-04 2005-12-22 Xenoport, Inc. Levodopa prodrugs, and compositions and uses thereof
WO2006044202A2 (en) * 2004-10-19 2006-04-27 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Enteric coated compositions that release active ingredient(s) in gastric fluid and intestinal fluid
EP1901720A2 (en) * 2005-06-23 2008-03-26 Spherics, Inc. Improved dosage forms for movement disorder treatment
EP1945188A2 (en) * 2005-11-07 2008-07-23 Teva Pharmaceutical Industries Ltd. Levodopa compositions

Also Published As

Publication number Publication date
RU2484815C2 (ru) 2013-06-20
AU2007267135B2 (en) 2013-03-07
CA2653683A1 (en) 2007-12-06
JP2009543761A (ja) 2009-12-10
US20080051459A1 (en) 2008-02-28
MX2008015339A (es) 2008-12-16
UA95954C2 (ru) 2011-09-26
WO2007138086A1 (en) 2007-12-06
CN101636145B (zh) 2014-04-23
IL195599A0 (en) 2009-09-01
BRPI0711882A2 (pt) 2012-01-10
HK1137931A1 (en) 2010-08-13
AU2007267135A1 (en) 2007-12-06
EP2063865A1 (en) 2009-06-03
ZA200810834B (en) 2010-03-31
RU2008150776A (ru) 2010-07-10
KR20090057349A (ko) 2009-06-05
CN101636145A (zh) 2010-01-27

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