NO20085418L - Langvarig, 24-timers tarmadministrering av levodopa/karbidopa - Google Patents
Langvarig, 24-timers tarmadministrering av levodopa/karbidopaInfo
- Publication number
- NO20085418L NO20085418L NO20085418A NO20085418A NO20085418L NO 20085418 L NO20085418 L NO 20085418L NO 20085418 A NO20085418 A NO 20085418A NO 20085418 A NO20085418 A NO 20085418A NO 20085418 L NO20085418 L NO 20085418L
- Authority
- NO
- Norway
- Prior art keywords
- levodopa
- carbidopa
- hour
- term
- long
- Prior art date
Links
- IVTMXOXVAHXCHI-YXLMWLKOSA-N (2s)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid;(2s)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1.NN[C@@](C(O)=O)(C)CC1=CC=C(O)C(O)=C1 IVTMXOXVAHXCHI-YXLMWLKOSA-N 0.000 title 1
- 230000007774 longterm Effects 0.000 title 1
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 abstract 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 229960004205 carbidopa Drugs 0.000 abstract 1
- TZFNLOMSOLWIDK-JTQLQIEISA-N carbidopa (anhydrous) Chemical compound NN[C@@](C(O)=O)(C)CC1=CC=C(O)C(O)=C1 TZFNLOMSOLWIDK-JTQLQIEISA-N 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
- 229960004502 levodopa Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Psychology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Sammendrag Fremgangsmåte for å behandle Parkinsons sykdom som omfatter tarmadministrering til en pasient med behov for det, av en farmasøytisk effektiv mengde av et preparat som omfatter levodopa og eventuelt karbidopa kontinuerlig over en periode på mer enn 16 timer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80988906P | 2006-05-31 | 2006-05-31 | |
PCT/EP2007/055275 WO2007138086A1 (en) | 2006-05-31 | 2007-05-31 | Long term 24 hour intestinal administration of levodopa/carbidopa |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20085418L true NO20085418L (no) | 2009-02-26 |
Family
ID=38434843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20085418A NO20085418L (no) | 2006-05-31 | 2008-12-30 | Langvarig, 24-timers tarmadministrering av levodopa/karbidopa |
Country Status (16)
Country | Link |
---|---|
US (1) | US20080051459A1 (no) |
EP (1) | EP2063865A1 (no) |
JP (1) | JP2009543761A (no) |
KR (1) | KR20090057349A (no) |
CN (1) | CN101636145B (no) |
AU (1) | AU2007267135B2 (no) |
BR (1) | BRPI0711882A2 (no) |
CA (1) | CA2653683A1 (no) |
HK (1) | HK1137931A1 (no) |
IL (1) | IL195599A0 (no) |
MX (1) | MX2008015339A (no) |
NO (1) | NO20085418L (no) |
RU (1) | RU2484815C2 (no) |
UA (1) | UA95954C2 (no) |
WO (1) | WO2007138086A1 (no) |
ZA (1) | ZA200810834B (no) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2485947C2 (ru) | 2008-02-06 | 2013-06-27 | Вокхардт Рисерч Сентер | Фармацевтические композиции энтакапона, леводопы и карбидопы с улучшенной биодоступностью |
SG10201505101VA (en) * | 2009-05-19 | 2015-07-30 | Neuroderm Ltd | Compositions For Continuous Administration Of Dopa Decarboxylase Inhibitors |
JP5902705B2 (ja) * | 2010-11-15 | 2016-04-13 | ニューロダーム リミテッドNeuroderm Ltd | L−ドーパ、ドーパデカルボキシラーゼ阻害剤、カテコール−o−メチルトランスフェラーゼ阻害剤、およびそれらのための組成物の継続的投与 |
EP2508174A1 (en) | 2011-04-06 | 2012-10-10 | Ljiljana Sovic Brkicic | Pharmaceutical composition |
EP2653179B1 (en) | 2012-04-17 | 2019-07-10 | Micrel Medical Devices S.A. | System for calculating and administering a drug to a patient with Parkinson's disease |
JP6257604B2 (ja) | 2012-06-05 | 2018-01-10 | ニューロダーム リミテッドNeuroderm Ltd | アポモルヒネと有機酸とを含む組成物およびその使用 |
US10258585B2 (en) | 2014-03-13 | 2019-04-16 | Neuroderm, Ltd. | DOPA decarboxylase inhibitor compositions |
ES2967693T3 (es) | 2014-03-13 | 2024-05-03 | Neuroderm Ltd | Composiciones del inhibidor de la dopa descarboxilasa |
PT3188725T (pt) | 2014-09-04 | 2021-01-27 | Lobsor Pharmaceuticals Ab | Composições farmacêuticas compreendendo levodopa, um inibidor de descarboxílase de dopamina e um inibidor de comt, e método de administração destes |
TWI755257B (zh) | 2014-10-21 | 2022-02-11 | 美商艾伯維有限公司 | 卡比多巴及左旋多巴之前藥及使用方法 |
MA41377A (fr) * | 2015-01-20 | 2017-11-28 | Abbvie Inc | Gel intestinal de lévodopa et de carbidona et procédés d'utilisation |
AU2016258179B2 (en) | 2015-05-06 | 2021-07-01 | Synagile Corporation | Pharmaceutical suspensions containing drug particles, devices for their administration, and methods of their use |
WO2017039525A1 (en) | 2015-09-04 | 2017-03-09 | Lobsor Pharmaceuticals Aktiebolag | Method of treating a dopamine related disorder in a subject by administering levodopa, in combination with a dopamine decarboxylase inhibitor and a catechol-o-methyltransferase inhibitor |
CN109715139A (zh) * | 2016-07-20 | 2019-05-03 | 艾伯维公司 | 左旋多巴和卡比多巴肠凝胶以及使用方法 |
ES2895054T3 (es) | 2016-08-18 | 2022-02-17 | Ilko Ilac Sanayi Ve Ticaret Anonim Sirketi | Fórmula de comprimido antiparkinson con perfil de disolución mejorado |
EP3758754A1 (en) | 2018-03-02 | 2021-01-06 | Chiesi Farmaceutici S.p.A. | A pharmaceutical formulation for intraduodenal administration comprising melevodopa and carbidopa |
CN112261940B (zh) | 2018-03-23 | 2024-02-27 | 劳波索尔制药有限公司 | 用于治疗神经退行性疾病的药物组合物的连续施用 |
CN111954523A (zh) * | 2018-03-29 | 2020-11-17 | 艾维制药有限责任公司 | 左旋多巴分次剂量组合物及用途 |
US11389398B2 (en) | 2019-05-14 | 2022-07-19 | Clexio Biosciences Ltd. | Gastroretentive treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease |
US11213502B1 (en) | 2020-11-17 | 2022-01-04 | Neuroderm, Ltd. | Method for treatment of parkinson's disease |
US11331293B1 (en) | 2020-11-17 | 2022-05-17 | Neuroderm, Ltd. | Method for treatment of Parkinson's disease |
US11844754B2 (en) | 2020-11-17 | 2023-12-19 | Neuroderm, Ltd. | Methods for treatment of Parkinson's disease |
WO2023126945A1 (en) * | 2022-01-03 | 2023-07-06 | Neuroderm, Ltd. | Methods and compositions for treating parkinson's disease |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9203594D0 (sv) * | 1992-11-30 | 1992-11-30 | Christer Nystroem | Laekemedel i dispersa system |
US6166081A (en) * | 1997-10-09 | 2000-12-26 | Kushnir; Moshe | Methods and apparatus for treatment of Parkinson's disease |
JP2004501190A (ja) * | 2000-06-23 | 2004-01-15 | テバ ファーマシューティカル インダストリーズ リミティド | 治療薬の胃部保留および制御された放出のための急速膨張する組成物とその組成物を含む剤形 |
FR2829027A1 (fr) * | 2001-08-29 | 2003-03-07 | Aventis Pharma Sa | Association avec un antagoniste du recepteur cb1, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement de la maladie de parkinson |
US20060013875A1 (en) * | 2002-05-29 | 2006-01-19 | Impax Laboratories, Inc. | Combination immediate release controlled release levodopa/carbidopa dosage forms |
ITMI20030827A1 (it) * | 2003-04-18 | 2004-10-19 | Unihart Corp | Composizione farmaceutica contenente l'associazione levodopa/carbidopa. |
WO2005042101A1 (en) * | 2003-10-20 | 2005-05-12 | Teva Pharmaceutical Industries Ltd. | Composition and dosage form for sustained effect of levodopa |
WO2005121069A1 (en) * | 2004-06-04 | 2005-12-22 | Xenoport, Inc. | Levodopa prodrugs, and compositions and uses thereof |
WO2006044202A2 (en) * | 2004-10-19 | 2006-04-27 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Enteric coated compositions that release active ingredient(s) in gastric fluid and intestinal fluid |
EP1901720A2 (en) * | 2005-06-23 | 2008-03-26 | Spherics, Inc. | Improved dosage forms for movement disorder treatment |
EP1945188A2 (en) * | 2005-11-07 | 2008-07-23 | Teva Pharmaceutical Industries Ltd. | Levodopa compositions |
-
2007
- 2007-05-31 UA UAA200814421A patent/UA95954C2/ru unknown
- 2007-05-31 MX MX2008015339A patent/MX2008015339A/es active IP Right Grant
- 2007-05-31 KR KR1020087031660A patent/KR20090057349A/ko not_active Application Discontinuation
- 2007-05-31 US US11/756,297 patent/US20080051459A1/en not_active Abandoned
- 2007-05-31 AU AU2007267135A patent/AU2007267135B2/en active Active
- 2007-05-31 CA CA002653683A patent/CA2653683A1/en not_active Withdrawn
- 2007-05-31 CN CN200780019726.8A patent/CN101636145B/zh active Active
- 2007-05-31 EP EP07729688A patent/EP2063865A1/en not_active Withdrawn
- 2007-05-31 WO PCT/EP2007/055275 patent/WO2007138086A1/en active Application Filing
- 2007-05-31 BR BRPI0711882-1A patent/BRPI0711882A2/pt not_active IP Right Cessation
- 2007-05-31 JP JP2009512591A patent/JP2009543761A/ja not_active Withdrawn
- 2007-05-31 ZA ZA200810834A patent/ZA200810834B/xx unknown
- 2007-05-31 RU RU2008150776/15A patent/RU2484815C2/ru active
-
2008
- 2008-11-30 IL IL195599A patent/IL195599A0/en unknown
- 2008-12-30 NO NO20085418A patent/NO20085418L/no not_active Application Discontinuation
-
2010
- 2010-04-21 HK HK10103896.7A patent/HK1137931A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
RU2484815C2 (ru) | 2013-06-20 |
AU2007267135B2 (en) | 2013-03-07 |
CA2653683A1 (en) | 2007-12-06 |
JP2009543761A (ja) | 2009-12-10 |
US20080051459A1 (en) | 2008-02-28 |
MX2008015339A (es) | 2008-12-16 |
UA95954C2 (ru) | 2011-09-26 |
WO2007138086A1 (en) | 2007-12-06 |
CN101636145B (zh) | 2014-04-23 |
IL195599A0 (en) | 2009-09-01 |
BRPI0711882A2 (pt) | 2012-01-10 |
HK1137931A1 (en) | 2010-08-13 |
AU2007267135A1 (en) | 2007-12-06 |
EP2063865A1 (en) | 2009-06-03 |
ZA200810834B (en) | 2010-03-31 |
RU2008150776A (ru) | 2010-07-10 |
KR20090057349A (ko) | 2009-06-05 |
CN101636145A (zh) | 2010-01-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |