ZA200810834B - Long term 24 hour intestinal administration of levodopa/carbidopa - Google Patents

Long term 24 hour intestinal administration of levodopa/carbidopa

Info

Publication number
ZA200810834B
ZA200810834B ZA200810834A ZA200810834A ZA200810834B ZA 200810834 B ZA200810834 B ZA 200810834B ZA 200810834 A ZA200810834 A ZA 200810834A ZA 200810834 A ZA200810834 A ZA 200810834A ZA 200810834 B ZA200810834 B ZA 200810834B
Authority
ZA
South Africa
Prior art keywords
carbidopa
levodopa
long term
intestinal administration
hour
Prior art date
Application number
ZA200810834A
Other languages
English (en)
Inventor
Dag Nyholm
Stefan Asberg
Roger Bolsoey
Mikael Tutschke-Saettler
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of ZA200810834B publication Critical patent/ZA200810834B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Psychology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
ZA200810834A 2006-05-31 2007-05-31 Long term 24 hour intestinal administration of levodopa/carbidopa ZA200810834B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80988906P 2006-05-31 2006-05-31

Publications (1)

Publication Number Publication Date
ZA200810834B true ZA200810834B (en) 2010-03-31

Family

ID=38434843

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200810834A ZA200810834B (en) 2006-05-31 2007-05-31 Long term 24 hour intestinal administration of levodopa/carbidopa

Country Status (16)

Country Link
US (1) US20080051459A1 (xx)
EP (1) EP2063865A1 (xx)
JP (1) JP2009543761A (xx)
KR (1) KR20090057349A (xx)
CN (1) CN101636145B (xx)
AU (1) AU2007267135B2 (xx)
BR (1) BRPI0711882A2 (xx)
CA (1) CA2653683A1 (xx)
HK (1) HK1137931A1 (xx)
IL (1) IL195599A0 (xx)
MX (1) MX2008015339A (xx)
NO (1) NO20085418L (xx)
RU (1) RU2484815C2 (xx)
UA (1) UA95954C2 (xx)
WO (1) WO2007138086A1 (xx)
ZA (1) ZA200810834B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0908052A2 (pt) * 2008-02-06 2015-08-11 Wockhardt Research Center Composições farmacêuticas de entacapone, levodopa e carbidopa com biodisponibilidade melhorada
EP3192500B1 (en) 2009-05-19 2020-12-02 Neuroderm Ltd Compositions for continuous administration of dopa decarboxylase inhibitors
PL2640358T3 (pl) 2010-11-15 2018-06-29 Neuroderm Ltd Ciągłe podawanie l-dopy, inhibitorów dopa-dekarboksylazy, inhibitorów katecholo-o-metylotransferazy i ich kompozycji
EP2508174A1 (en) 2011-04-06 2012-10-10 Ljiljana Sovic Brkicic Pharmaceutical composition
EP2653179B1 (en) 2012-04-17 2019-07-10 Micrel Medical Devices S.A. System for calculating and administering a drug to a patient with Parkinson's disease
BR112014030265A2 (pt) 2012-06-05 2017-06-27 Neuroderm Ltd composição farmacêutica líquida ou semissólida e método para tratar uma doença ou distúrbio neurológico ou de movimento.
DK3777833T3 (da) 2014-03-13 2023-12-18 Neuroderm Ltd Dopa-decarboxylase-inhibitorsammensætninger
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
CA2959307C (en) 2014-09-04 2023-03-28 Lobsor Pharmaceuticals Aktiebolag Pharmaceutical compositions comprising levodopa, a dopamine decarboxylase inhibitor and a comt inhibitor and method of administration thereof
KR102537018B1 (ko) 2014-10-21 2023-05-30 애브비 인코포레이티드 카르비도파 및 l-도파 프로드럭 및 파킨슨병을 치료하기 위한 이들의 용도
MA41377A (fr) * 2015-01-20 2017-11-28 Abbvie Inc Gel intestinal de lévodopa et de carbidona et procédés d'utilisation
AU2016258179B2 (en) 2015-05-06 2021-07-01 Synagile Corporation Pharmaceutical suspensions containing drug particles, devices for their administration, and methods of their use
WO2017039525A1 (en) 2015-09-04 2017-03-09 Lobsor Pharmaceuticals Aktiebolag Method of treating a dopamine related disorder in a subject by administering levodopa, in combination with a dopamine decarboxylase inhibitor and a catechol-o-methyltransferase inhibitor
CN109715139A (zh) * 2016-07-20 2019-05-03 艾伯维公司 左旋多巴和卡比多巴肠凝胶以及使用方法
WO2018034626A1 (en) 2016-08-18 2018-02-22 İlko İlaç Sanayi Ve Ticaret Anonim Şirketi Antiparkinson tablet formulation with improved dissolution profile
EP3758754A1 (en) 2018-03-02 2021-01-06 Chiesi Farmaceutici S.p.A. A pharmaceutical formulation for intraduodenal administration comprising melevodopa and carbidopa
US11547689B2 (en) 2018-03-23 2023-01-10 Intrance International Ab Continuous administration of pharmaceutical composition for treatment of neurodegenerative disorders
CN111954523A (zh) * 2018-03-29 2020-11-17 艾维制药有限责任公司 左旋多巴分次剂量组合物及用途
CA3139217A1 (en) 2019-05-14 2020-11-19 Clexio Biosciences Ltd. Treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
WO2023126945A1 (en) * 2022-01-03 2023-07-06 Neuroderm, Ltd. Methods and compositions for treating parkinson's disease

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9203594D0 (sv) * 1992-11-30 1992-11-30 Christer Nystroem Laekemedel i dispersa system
US6166081A (en) * 1997-10-09 2000-12-26 Kushnir; Moshe Methods and apparatus for treatment of Parkinson's disease
CA2412490A1 (en) * 2000-06-23 2002-01-03 Moshe Fleshner-Barak Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition
FR2829027A1 (fr) * 2001-08-29 2003-03-07 Aventis Pharma Sa Association avec un antagoniste du recepteur cb1, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement de la maladie de parkinson
US20060013875A1 (en) * 2002-05-29 2006-01-19 Impax Laboratories, Inc. Combination immediate release controlled release levodopa/carbidopa dosage forms
ITMI20030827A1 (it) * 2003-04-18 2004-10-19 Unihart Corp Composizione farmaceutica contenente l'associazione levodopa/carbidopa.
AU2004285436C1 (en) * 2003-10-20 2009-07-16 Teva Pharmaceutical Industries Ltd. Composition and dosage form for sustained effect of levodopa
MXPA06014132A (es) * 2004-06-04 2007-03-07 Xenoport Inc Profarmacos de levodopa y sus composiciones y usos.
WO2006044202A2 (en) * 2004-10-19 2006-04-27 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Enteric coated compositions that release active ingredient(s) in gastric fluid and intestinal fluid
WO2007002516A2 (en) * 2005-06-23 2007-01-04 Spherics, Inc. Improved dosage forms for movement disorder treatment
WO2007056570A2 (en) * 2005-11-07 2007-05-18 Teva Pharmaceutical Industries Ltd. Levodopa compositions

Also Published As

Publication number Publication date
KR20090057349A (ko) 2009-06-05
CN101636145A (zh) 2010-01-27
AU2007267135A1 (en) 2007-12-06
JP2009543761A (ja) 2009-12-10
BRPI0711882A2 (pt) 2012-01-10
MX2008015339A (es) 2008-12-16
RU2484815C2 (ru) 2013-06-20
HK1137931A1 (en) 2010-08-13
UA95954C2 (ru) 2011-09-26
CN101636145B (zh) 2014-04-23
NO20085418L (no) 2009-02-26
EP2063865A1 (en) 2009-06-03
US20080051459A1 (en) 2008-02-28
RU2008150776A (ru) 2010-07-10
WO2007138086A1 (en) 2007-12-06
CA2653683A1 (en) 2007-12-06
IL195599A0 (en) 2009-09-01
AU2007267135B2 (en) 2013-03-07

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