NO20084744L - Trisubstituerte 1,2,4-triazoler - Google Patents
Trisubstituerte 1,2,4-triazolerInfo
- Publication number
- NO20084744L NO20084744L NO20084744A NO20084744A NO20084744L NO 20084744 L NO20084744 L NO 20084744L NO 20084744 A NO20084744 A NO 20084744A NO 20084744 A NO20084744 A NO 20084744A NO 20084744 L NO20084744 L NO 20084744L
- Authority
- NO
- Norway
- Prior art keywords
- positive allosteric
- allosteric modulators
- trisubstituted
- triazoles
- relates
- Prior art date
Links
- 150000000178 1,2,4-triazoles Chemical class 0.000 title 1
- 230000003281 allosteric effect Effects 0.000 abstract 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract 1
- 102000019315 Nicotinic acetylcholine receptors Human genes 0.000 abstract 1
- 108050006807 Nicotinic acetylcholine receptors Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229960002715 nicotine Drugs 0.000 abstract 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940042055 systemic antimycotics triazole derivative Drugs 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Den foreliggende oppfinnelsen angår 3-anilin-5-aryltriazolderivater og analoger eller farmasøytisk akseptable salter derav, metoder for å fremstille dem, farmasøytiske sammensetninger inneholdende dem og deres anvendelse i terapi, ifølge formel (I). Oppfinnelsen angår spesielt positive allosteriske modulatorer av nikotinacetylkolinreseptorer, slike positive allosteriske modulatorer har evnen til å øke effektiviteten av nikotinreseptoragonister.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06112754 | 2006-04-19 | ||
PCT/EP2007/053829 WO2007118903A1 (en) | 2006-04-19 | 2007-04-19 | Trisubstituted 1,2,4-triazoles |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20084744L true NO20084744L (no) | 2008-11-10 |
NO342797B1 NO342797B1 (no) | 2018-08-06 |
Family
ID=37814207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20084744A NO342797B1 (no) | 2006-04-19 | 2008-11-10 | Trisubstituerte 1,2,4-triazoler |
Country Status (22)
Country | Link |
---|---|
US (1) | US8143419B2 (no) |
EP (1) | EP2010516B1 (no) |
JP (1) | JP5439169B2 (no) |
KR (1) | KR101465413B1 (no) |
CN (1) | CN101472911B (no) |
AR (1) | AR060537A1 (no) |
AU (1) | AU2007239498B2 (no) |
BR (1) | BRPI0710819A2 (no) |
CA (1) | CA2648157C (no) |
EA (1) | EA016289B1 (no) |
ES (1) | ES2501946T3 (no) |
HK (1) | HK1135375A1 (no) |
IL (1) | IL194744A (no) |
JO (1) | JO3019B1 (no) |
MX (1) | MX2008013457A (no) |
MY (1) | MY147212A (no) |
NO (1) | NO342797B1 (no) |
NZ (1) | NZ572468A (no) |
TW (1) | TWI408132B (no) |
UA (1) | UA95281C2 (no) |
WO (1) | WO2007118903A1 (no) |
ZA (1) | ZA200808916B (no) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO3019B1 (ar) | 2006-04-19 | 2016-09-05 | Janssen Pharmaceutica Nv | ثلاثي مستبدل 4،2،1-ثلاثي زولات |
WO2008028903A2 (en) * | 2006-09-04 | 2008-03-13 | Neurosearch A/S | Pharmaceutical combinations of a nicotine receptor modulator and a cognitive enhancer |
JO2784B1 (en) * | 2007-10-18 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | 5,3,1 - Triazole substitute derivative |
ES2424023T3 (es) * | 2007-10-18 | 2013-09-26 | Janssen Pharmaceutica N.V. | 1,2,4-triazoles trisustituidos |
AU2009226988B2 (en) | 2008-03-19 | 2013-05-23 | Janssen Pharmaceutica Nv | Trisubstituted 1, 2, 4 -triazoles as nicotinic acetylcholine receptor modulators |
BRPI0912196A2 (pt) | 2008-05-09 | 2015-10-06 | Janssen Pharmaceutica Nv | pirazóis trissubstituídos como moduladores do receptor de acetilcolina. |
KR101710197B1 (ko) * | 2009-09-17 | 2017-02-24 | 얀센 파마슈티카 엔.브이. | 치환된 n-페닐-1-(4-피리디닐)-1h-피라졸-3-아민 |
JO3078B1 (ar) * | 2009-11-27 | 2017-03-15 | Janssen Pharmaceutica Nv | مورفولينوثيازولات بصفتها منظمات الوستيرية نوع الفا 7 موجبة |
CA2825519A1 (en) | 2011-02-03 | 2012-09-08 | Lupin Limited | Pyrrole derivatives used as modulators of alpha7 nachr |
CA2826792A1 (en) | 2011-02-23 | 2012-08-30 | Lupin Limited | Heteroaryl derivatives as alpha7 nachr modulators |
EP2678315B1 (en) | 2011-02-25 | 2015-12-16 | Janssen Pharmaceutica, N.V. | (Pyridin-4-yl)benzylamides as allosteric modulators of alpha 7 nAChR |
EP2691368A1 (en) | 2011-03-31 | 2014-02-05 | Lupin Limited | Pyrrole derivatives as nicotinic acetylcholine receptor modulators for use in the treatment of neurodegenerative disorders such as alzheimer's and parkinson's disease |
US8946432B2 (en) | 2011-07-05 | 2015-02-03 | Lupin Limited | Biaryl derivatives as nAChR modulators |
US9388196B2 (en) | 2012-03-06 | 2016-07-12 | Lupin Limited | Thiazole derivatives as alpha 7 nAChR modulators |
WO2014072957A1 (en) | 2012-11-12 | 2014-05-15 | Lupin Limited | Thiazole derivatives as alpha 7 nachr modulators |
EP2945941B1 (en) | 2013-01-16 | 2016-12-07 | Lupin Limited | Pyrrole derivatives as alpha 7 nachr modulators |
EP2970180A1 (en) | 2013-03-13 | 2016-01-20 | Lupin Limited | Pyrrole derivatives as alpha 7 nachr modulators |
TW201446243A (zh) | 2013-06-03 | 2014-12-16 | Lupin Ltd | 4-(5-(4-氯苯基)-2-(2-環丙基乙醯基)-1,4-二甲基-1氫-吡咯-3-基)苯磺醯胺作為α7尼古丁乙醯膽鹼受體調節劑 |
US9504680B2 (en) | 2013-06-17 | 2016-11-29 | Lupin Limited | Pyrrole derivatives as alpha 7 nAChR modulators |
EP3053920B1 (en) | 2015-02-05 | 2020-04-08 | AB Science | Compounds with anti-tumoral activity |
CN110835336B (zh) * | 2018-08-16 | 2022-10-04 | 中国药科大学 | 含氧杂环取代唑类化合物及其用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0248523B1 (en) | 1986-05-07 | 1991-10-16 | FISONS plc | Pyrazoles |
FR2792314B1 (fr) | 1999-04-15 | 2001-06-01 | Adir | Nouveaux composes aminotriazoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
ATE257827T1 (de) | 1999-07-21 | 2004-01-15 | Hoffmann La Roche | Triazolderivate |
FR2802530B1 (fr) | 1999-12-17 | 2002-02-22 | Sanofi Synthelabo | Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant |
US7300933B2 (en) | 2002-05-07 | 2007-11-27 | Neurosearch A/S | Diazabicyclic biaryl derivatives |
CN1326857C (zh) * | 2002-09-30 | 2007-07-18 | 神经研究公司 | 新的1,4-二氮杂双环烷烃衍生物、其制备和应用 |
WO2005004818A2 (en) * | 2003-07-09 | 2005-01-20 | Imclone Systems Incorporated | Heterocyclic compounds and their use as anticancer agents |
US20090018150A1 (en) | 2003-07-24 | 2009-01-15 | Asterand Uk Limited | 5-Ht2b Receptor Antagonists |
FR2862647B1 (fr) | 2003-11-25 | 2008-07-04 | Aventis Pharma Sa | Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant |
WO2006064375A2 (en) | 2004-12-16 | 2006-06-22 | Ab Science | Aminoaryl substituted five-membered ring heterocyclic compounds for the treatment of diseases |
CN101263130B (zh) | 2005-09-13 | 2011-03-09 | 詹森药业有限公司 | 2-苯胺-4-芳基取代的噻唑衍生物 |
JO3019B1 (ar) | 2006-04-19 | 2016-09-05 | Janssen Pharmaceutica Nv | ثلاثي مستبدل 4،2،1-ثلاثي زولات |
-
2007
- 2007-04-03 JO JOP/2007/0105A patent/JO3019B1/ar active
- 2007-04-18 TW TW096113561A patent/TWI408132B/zh active
- 2007-04-18 AR ARP070101670A patent/AR060537A1/es active IP Right Grant
- 2007-04-19 EP EP07728289.5A patent/EP2010516B1/en active Active
- 2007-04-19 US US12/297,059 patent/US8143419B2/en not_active Expired - Fee Related
- 2007-04-19 BR BRPI0710819-2A patent/BRPI0710819A2/pt not_active Application Discontinuation
- 2007-04-19 KR KR1020087027740A patent/KR101465413B1/ko active IP Right Grant
- 2007-04-19 CN CN200780022922.0A patent/CN101472911B/zh not_active Expired - Fee Related
- 2007-04-19 WO PCT/EP2007/053829 patent/WO2007118903A1/en active Application Filing
- 2007-04-19 EA EA200870448A patent/EA016289B1/ru not_active IP Right Cessation
- 2007-04-19 AU AU2007239498A patent/AU2007239498B2/en not_active Ceased
- 2007-04-19 NZ NZ572468A patent/NZ572468A/en not_active IP Right Cessation
- 2007-04-19 UA UAA200811654A patent/UA95281C2/ru unknown
- 2007-04-19 JP JP2009505892A patent/JP5439169B2/ja not_active Expired - Fee Related
- 2007-04-19 MX MX2008013457A patent/MX2008013457A/es active IP Right Grant
- 2007-04-19 ES ES07728289.5T patent/ES2501946T3/es active Active
- 2007-04-19 CA CA2648157A patent/CA2648157C/en active Active
-
2008
- 2008-10-16 MY MYPI20084130A patent/MY147212A/en unknown
- 2008-10-17 ZA ZA2008/08916A patent/ZA200808916B/en unknown
- 2008-10-22 IL IL194744A patent/IL194744A/en active IP Right Grant
- 2008-11-10 NO NO20084744A patent/NO342797B1/no not_active IP Right Cessation
-
2009
- 2009-12-16 HK HK09111816A patent/HK1135375A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES2501946T3 (es) | 2014-10-02 |
BRPI0710819A2 (pt) | 2011-08-23 |
AR060537A1 (es) | 2008-06-25 |
KR101465413B1 (ko) | 2014-12-01 |
ZA200808916B (en) | 2011-12-28 |
MY147212A (en) | 2012-11-14 |
MX2008013457A (es) | 2008-10-30 |
CN101472911B (zh) | 2014-07-02 |
HK1135375A1 (en) | 2010-06-04 |
CA2648157A1 (en) | 2007-10-25 |
TWI408132B (zh) | 2013-09-11 |
US8143419B2 (en) | 2012-03-27 |
EA016289B1 (ru) | 2012-03-30 |
UA95281C2 (en) | 2011-07-25 |
TW200815396A (en) | 2008-04-01 |
AU2007239498B2 (en) | 2012-08-23 |
WO2007118903A1 (en) | 2007-10-25 |
EP2010516B1 (en) | 2014-07-02 |
CA2648157C (en) | 2012-04-03 |
IL194744A0 (en) | 2009-08-03 |
JP2009534357A (ja) | 2009-09-24 |
US20090253691A1 (en) | 2009-10-08 |
JP5439169B2 (ja) | 2014-03-12 |
EA200870448A1 (ru) | 2009-02-27 |
NO342797B1 (no) | 2018-08-06 |
CN101472911A (zh) | 2009-07-01 |
NZ572468A (en) | 2010-07-30 |
KR20090008335A (ko) | 2009-01-21 |
IL194744A (en) | 2016-10-31 |
EP2010516A1 (en) | 2009-01-07 |
JO3019B1 (ar) | 2016-09-05 |
AU2007239498A1 (en) | 2007-10-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20084744L (no) | Trisubstituerte 1,2,4-triazoler | |
MY152486A (en) | Trisubstituted 1,2,4 - triazoles as nicotinic acetylcholine receptor modulators | |
EA201071288A1 (ru) | Тризамещенные пиразолы в качестве модуляторов рецепторов ацетилхолина | |
NO20070566L (no) | Azin-karboksamider som antikreftmiddel | |
NO20082709L (no) | Kjemiske forbindelser | |
MY160728A (en) | Morpholinothiazoles as alpha 7 positive allosteric modulators | |
WO2009155121A3 (en) | Inhibitors of pi3 kinase | |
NO20071246L (no) | Kinazolinonderivater og deres anvendelse som B-RAF-inhibitorer. | |
JO2784B1 (en) | 5,3,1 - Triazole substitute derivative | |
NO20062004L (no) | Forlenget frigjoring farmasoytiske blandinger omfattene aplindor og derivater derav | |
NO20084363L (no) | 2-Substituerte 4-benzylftalazinonderivater som histamin H1- og H3-antagonister | |
NO20070199L (no) | Substituerte kinazoloner som anti-kreftmidler | |
NO20084489L (no) | Azolopyrimidiner som inhibitorer av cannabinoid 1 aktivitet | |
NO20070336L (no) | Indolderivater som histamin-reseptorantagonister | |
NO20084202L (no) | 4-anilinoquinolin-3-carboksamider som CSF-1R kinase inhibitorer | |
ATE502017T1 (de) | Pyrazolderivate als p2x7-modulatoren | |
ZA201002596B (en) | 1,2,3-triazole derivatives for use as stearoyl-coa destaurase inhibitors | |
UA83862C2 (ru) | Производные тиазола как модуляторы рецепторов канабиноидов | |
NO20076060L (no) | Piperidin-4-yl-amidderivater og deres anvendelse som SST-reseptor subtype 5-antagonister | |
MX2009004745A (es) | Derivados de 1,2,3-triazol como inhibidores del receptor sigma. | |
MX2010003923A (es) | Formulacion farmaceutica de valsartan. | |
NO20076357L (no) | Azabicykliske heterocykler som cannabinoid reseptor modulatorer | |
EA201270428A1 (ru) | Замещенные n-фенил-1-(4-пиридинил)-1н-пиразол-3-амины | |
MX2009011543A (es) | Metodo para la produccion de la 2,4'-dimetil-3-piperidino-propiofe nona (tolperisona), altamente pura, composiciones farmaceuticas que contienen la misma al igual que formulaciones de ingrediente activo que contienen la tolperisona. | |
MX2011010732A (es) | Pirimidinas sustituidas por imidazol utiles en el tratamiento de trastornos relacionados con glucogeno sintasa cinasa 3 como la enfermedad de alzheimer. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |