NO20084188L - Folding av protein - Google Patents

Folding av protein

Info

Publication number
NO20084188L
NO20084188L NO20084188A NO20084188A NO20084188L NO 20084188 L NO20084188 L NO 20084188L NO 20084188 A NO20084188 A NO 20084188A NO 20084188 A NO20084188 A NO 20084188A NO 20084188 L NO20084188 L NO 20084188L
Authority
NO
Norway
Prior art keywords
folding
biologically active
growth factors
functional analog
transforming growth
Prior art date
Application number
NO20084188A
Other languages
English (en)
Norwegian (no)
Inventor
Mark William James Ferguson
Hugh Gerard Laverty
Nick Occleston
Sharon O'kane
Phillip Mellors
Simon Higginbottom
Original Assignee
Renovo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Renovo Ltd filed Critical Renovo Ltd
Publication of NO20084188L publication Critical patent/NO20084188L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20084188A 2006-03-11 2008-10-07 Folding av protein NO20084188L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0604964.7A GB0604964D0 (en) 2006-03-11 2006-03-11 Protein folding
PCT/GB2007/000814 WO2007104934A2 (fr) 2006-03-11 2007-03-09 Repliement de protéines

Publications (1)

Publication Number Publication Date
NO20084188L true NO20084188L (no) 2008-10-07

Family

ID=36241465

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20084188A NO20084188L (no) 2006-03-11 2008-10-07 Folding av protein

Country Status (15)

Country Link
US (1) US7893221B2 (fr)
EP (1) EP1996605A2 (fr)
JP (1) JP2009529571A (fr)
KR (1) KR20080106449A (fr)
CN (1) CN101437837A (fr)
AR (1) AR065829A1 (fr)
AU (1) AU2007226334A1 (fr)
BR (1) BRPI0708751A2 (fr)
CA (1) CA2645109A1 (fr)
GB (1) GB0604964D0 (fr)
IL (1) IL193696A0 (fr)
MX (1) MX2008011706A (fr)
NO (1) NO20084188L (fr)
RU (1) RU2008140113A (fr)
WO (1) WO2007104934A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0604966D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Medicaments and proteins
GB0604938D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Proteins, nucleic acids and medicaments
EP3744728A1 (fr) * 2013-02-12 2020-12-02 Bristol-Myers Squibb Company Procédés de repliement de protéine utilisant la filtration tangentielle
CN106353445A (zh) * 2016-09-30 2017-01-25 王荔 一种iptg含量的检测方法
CN108753753B (zh) * 2018-05-28 2022-04-22 中国林业科学研究院林业研究所 Lrr受体激酶-pxy的纯化方法
KR20240064367A (ko) * 2022-11-04 2024-05-13 주식회사 대웅제약 TGF-β3 단백질의 정제방법

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4051848A (en) * 1976-03-01 1977-10-04 Levine Norman S Synthetic skin wound dressing
IL78197A (en) 1985-03-22 1991-07-18 Genentech Inc Nucleic acid encoding tgf-beta and its uses
US6559123B1 (en) * 1985-04-19 2003-05-06 Osi Pharmaceuticals, Inc. Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof
US5135915A (en) * 1988-10-14 1992-08-04 Genentech, Inc. Method for the treatment of grafts prior to transplantation using TGF-.beta.
AU6870791A (en) 1989-10-18 1991-05-16 Creative Biomolecules, Inc. Biosynthetic constructs of tgf-beta
GB8927546D0 (en) * 1989-12-06 1990-02-07 Ciba Geigy Process for the production of biologically active tgf-beta
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
GB9206861D0 (en) 1992-03-28 1992-05-13 Univ Manchester Wound healing and treatment of fibrotic disorders
WO1993019783A1 (fr) * 1992-04-01 1993-10-14 The Whittier Institute For Diabetes And Endocrinology Procedes permettant d'inhiber ou de stimuler la formation de cicatrices dans le systeme nerveux central
US5411940A (en) * 1993-09-29 1995-05-02 Alcon Laboratories, Inc. Use of TGF-β3 to reduce the formation of scar tissue in response to corneal trauma
US5399677A (en) 1993-12-07 1995-03-21 Genetics Institute, Inc. Mutants of bone morphogenetic proteins
TW440566B (en) 1994-07-25 2001-06-16 Novartis Ag Novel process for the production of biologically active dimeric protein
CA2225963C (fr) 1995-07-25 2008-02-05 Novartis Ag Cristaux de facteur de croissance transformant beta
EP0943690B1 (fr) 1995-12-21 2006-11-29 Ajinomoto Co., Inc. Procede pour replier l'activine a humaine
EP0914168A1 (fr) * 1996-05-03 1999-05-12 Innogenetics N.V. Nouveaux medicaments contenant de la gelatine reticulee avec des polysaccharides oxydes
US20020052026A1 (en) * 1997-10-08 2002-05-02 Steven M. Vicik Methods of refolding proteins
US6677432B1 (en) 1998-10-07 2004-01-13 Stryker Corporation Mutations of the C-terminal portion of TGF-β superfamily proteins
WO2000020612A2 (fr) 1998-10-07 2000-04-13 Syngenta Participations Ag Proteines vegetales a action therapeutique
JP2002539172A (ja) 1999-03-17 2002-11-19 ノバルティス アクチエンゲゼルシャフト Ｔｇｆ−ベータを含む医薬組成物
WO2000056879A1 (fr) 1999-03-22 2000-09-28 Universität Zürich ANTAGONISTES DE LA SUPERFAMILLE DU FACTEUR DE CROISSANCE TRANSFORMANT $g(b)
AR027765A1 (es) 2000-04-03 2003-04-09 Monsanto Technology Llc Expresion y purificacion de polipeptidos bioactivos autenticos a partir de plantas
EP1279677B1 (fr) * 2000-04-25 2007-03-07 Otsuka Pharmaceutical Co., Ltd. Peptides gd3 mimetiques
US20040078851A1 (en) * 2000-05-02 2004-04-22 Ning Huang Production of human growth factors in monocot seeds
DE10026713A1 (de) 2000-05-30 2001-12-06 Walter Sebald Mutein einer Kette eines Proteins aus der Superfamilie des Wachstumsfaktors TGF-beta
WO2002012336A2 (fr) 2000-08-09 2002-02-14 Curis, Inc. THERAPEUTIQUES DU TGF-β, COMPOSITIONS ET PROCEDES D'UTILISATION
AU2002257703A1 (en) 2001-03-23 2002-10-08 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Use of cytokines of the tgf-beta superfamily for the treatment and diagnosis of skin related disorders
WO2002099067A2 (fr) 2001-06-05 2002-12-12 Oishi Karen K Expression genique et production de proteines tgf-b comprenant une substance inhibitrice mullerienne bioactive issue de vegetaux
AU2003266096A1 (en) 2002-09-27 2004-04-19 Centro De Ingenieria Genetica Y Biotecnologia Vector for the production of transplastomic angiosperm plants
EP1784203B1 (fr) 2004-08-19 2010-06-30 Biogen Idec MA Inc. Repliement des proteines de la famille du facteur de croissance transformant beta
US20060162026A1 (en) 2004-12-23 2006-07-20 Karen Oishi Expressing TGF-beta proteins in plant plastids
EP1915169A2 (fr) * 2005-07-12 2008-04-30 Renovo Limited Compositions pharmaceutiques comprenant un membre d'une superfamille tgf-beta
GB0514262D0 (en) 2005-07-12 2005-08-17 Renovo Ltd Promotion of epithelial regeneration
GB0604938D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Proteins, nucleic acids and medicaments
GB0604966D0 (en) 2006-03-11 2006-04-19 Renovo Ltd Medicaments and proteins
GB0617816D0 (en) 2006-09-11 2006-10-18 Renovo Ltd Nucleic acids and methods of protein expression

Also Published As

Publication number Publication date
IL193696A0 (en) 2011-08-01
MX2008011706A (es) 2008-09-26
WO2007104934A2 (fr) 2007-09-20
EP1996605A2 (fr) 2008-12-03
US7893221B2 (en) 2011-02-22
CA2645109A1 (fr) 2007-09-20
AR065829A1 (es) 2009-07-08
CN101437837A (zh) 2009-05-20
WO2007104934A3 (fr) 2008-01-03
AU2007226334A1 (en) 2007-09-20
BRPI0708751A2 (pt) 2011-06-28
JP2009529571A (ja) 2009-08-20
GB0604964D0 (en) 2006-04-19
US20090181430A1 (en) 2009-07-16
RU2008140113A (ru) 2010-04-20
KR20080106449A (ko) 2008-12-05

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application