NO20083249L - Imidazolderivater for behandling av gastrointestinale forstyrrelser - Google Patents

Imidazolderivater for behandling av gastrointestinale forstyrrelser

Info

Publication number
NO20083249L
NO20083249L NO20083249A NO20083249A NO20083249L NO 20083249 L NO20083249 L NO 20083249L NO 20083249 A NO20083249 A NO 20083249A NO 20083249 A NO20083249 A NO 20083249A NO 20083249 L NO20083249 L NO 20083249L
Authority
NO
Norway
Prior art keywords
treatment
gastrointestinal disorders
imidazole derivatives
compounds
gabab
Prior art date
Application number
NO20083249A
Other languages
English (en)
Norwegian (no)
Inventor
Udo Bauer
Wayne Brailsford
Linda Gustafsson
Maria Saxin
Tor Svensson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20083249L publication Critical patent/NO20083249L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88Nitrogen atoms, e.g. allantoin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20083249A 2005-12-23 2008-07-22 Imidazolderivater for behandling av gastrointestinale forstyrrelser NO20083249L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0502906 2005-12-23
PCT/SE2006/001462 WO2007073298A1 (en) 2005-12-23 2006-12-21 Imidazole derivatives for the treatment of gastrointestinal disorders

Publications (1)

Publication Number Publication Date
NO20083249L true NO20083249L (no) 2008-07-23

Family

ID=38188929

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083249A NO20083249L (no) 2005-12-23 2008-07-22 Imidazolderivater for behandling av gastrointestinale forstyrrelser

Country Status (12)

Country Link
US (1) US7745474B2 (zh)
EP (1) EP1966154A4 (zh)
JP (1) JP2009521428A (zh)
KR (1) KR20080091452A (zh)
CN (1) CN101341130A (zh)
AU (1) AU2006327315A1 (zh)
BR (1) BRPI0620372A2 (zh)
CA (1) CA2632016A1 (zh)
IL (1) IL191750A0 (zh)
NO (1) NO20083249L (zh)
WO (1) WO2007073298A1 (zh)
ZA (1) ZA200805159B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0401653D0 (sv) * 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
CA2632016A1 (en) 2005-12-23 2007-06-28 Astrazeneca Ab Imidazole derivatives for the treatment of gastrointestinal disorders
AU2006327316A1 (en) * 2005-12-23 2007-06-28 Astrazeneca Ab Imidazoles as GABA-B receptor modulators
AU2006327314A1 (en) * 2005-12-23 2007-06-28 Astrazeneca Ab Pyrazoles for the treatment of GERD and IBS
US20080312291A1 (en) * 2005-12-23 2008-12-18 Udo Bauer Heterocyclic Gaba-b Modulators
EP1968947A1 (en) * 2005-12-23 2008-09-17 AstraZeneca AB Gaba-b receptor modulators
CN103403136A (zh) 2011-01-04 2013-11-20 卢布里佐尔公司 具有延长防抖动耐久性的无级变速器流体
TW201623257A (zh) 2014-05-09 2016-07-01 奧利安公司 藥理活性之喹唑啉二酮衍生物

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH449046A (de) 1963-07-09 1967-12-31 Ciba Geigy Verfahren zur Herstellung neuer Aminosäuren
US3876655A (en) 1971-08-18 1975-04-08 Beecham Group Ltd Anti-inflammatory acyl imidazoles
US4659720A (en) 1982-12-20 1987-04-21 Merck & Co., Inc. 5-amino or substituted amino imidazoles useful to treat coccidiosis
GB8425872D0 (en) 1984-10-12 1984-11-21 Ciba Geigy Ag Chemical compounds
GB8624879D0 (en) 1986-10-17 1986-11-19 May & Baker Ltd Compositions of matter
GB8820266D0 (en) 1988-08-26 1988-09-28 Smith Kline French Lab Compounds
GB8911017D0 (en) 1989-05-13 1989-06-28 Ciba Geigy Ag Substituted aminoalkylphosphinic acids
FR2663934B1 (fr) 1990-06-27 1994-06-03 Adir Nouveaux derives de l'acide 4 - amino butyrique, leur procede de preparation et les preparations pharmaceutiques qui les contiennent.
US5214063A (en) 1990-06-27 1993-05-25 Adir Et Compagnie 4-aminobutyric acid compounds, compositions and methods of use for treating disorders related to a dysfunction of GABAB receptors
DE4213750A1 (de) 1992-04-25 1993-10-28 Basf Ag Verfahren zur Herstellung von 3-(Hydroxyphenyl)-propionaldehyden und gegebenenfalls der Herstellung von 3-(hydroxyphenyl)-propanolen
JPH08507068A (ja) 1993-02-26 1996-07-30 シェリング・コーポレーション 2−ベンジル−多環式グアニン誘導体およびそれらの製造方法
FR2722192A1 (fr) 1994-07-06 1996-01-12 Adir Nouveaux derives de l'acide 4-amino butyrique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU1811397A (en) 1996-02-29 1997-09-16 Kissei Pharmaceutical Co. Ltd. Imidazole derivatives and vascular wall thickening inhibitor
SE9603408D0 (sv) * 1996-09-18 1996-09-18 Astra Ab Medical use
SE9904508D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
SE9904507D0 (sv) 1999-12-09 1999-12-09 Astra Ab New compounds
WO2001090141A2 (en) 2000-05-25 2001-11-29 Merck Frosst Canada & Co. Gb1c isoform and nucleotides
WO2002000651A2 (en) 2000-06-27 2002-01-03 Bristol-Myers Squibb Pharma Company Factor xa inhibitors
US20040259883A1 (en) 2001-09-14 2004-12-23 Hiroshi Sakashita Thiazolidine derivative and medicinal use thereof
GB0209481D0 (en) 2002-04-24 2002-06-05 Novartis Ag Organic compounds
SE0401653D0 (sv) 2004-06-24 2004-06-24 Astrazeneca Ab New compounds
US20080312291A1 (en) 2005-12-23 2008-12-18 Udo Bauer Heterocyclic Gaba-b Modulators
AU2006327314A1 (en) 2005-12-23 2007-06-28 Astrazeneca Ab Pyrazoles for the treatment of GERD and IBS
AU2006327316A1 (en) 2005-12-23 2007-06-28 Astrazeneca Ab Imidazoles as GABA-B receptor modulators
CA2632016A1 (en) 2005-12-23 2007-06-28 Astrazeneca Ab Imidazole derivatives for the treatment of gastrointestinal disorders
EP1968947A1 (en) 2005-12-23 2008-09-17 AstraZeneca AB Gaba-b receptor modulators
US20080262064A1 (en) 2007-04-18 2008-10-23 Astrazeneca Ab Novel Compounds For The Treatment Of GI Disorders 682
US20090023704A1 (en) 2007-04-18 2009-01-22 Astrazeneca Ab Novel Compounds 737

Also Published As

Publication number Publication date
AU2006327315A1 (en) 2007-06-28
EP1966154A4 (en) 2011-01-26
US20090005428A1 (en) 2009-01-01
JP2009521428A (ja) 2009-06-04
BRPI0620372A2 (pt) 2011-11-08
ZA200805159B (en) 2009-03-25
WO2007073298A1 (en) 2007-06-28
IL191750A0 (en) 2008-12-29
KR20080091452A (ko) 2008-10-13
CA2632016A1 (en) 2007-06-28
US7745474B2 (en) 2010-06-29
EP1966154A1 (en) 2008-09-10
CN101341130A (zh) 2009-01-07

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