NO20083171L - Ny samling av HCDR3 omrader og anvendelser derav - Google Patents

Ny samling av HCDR3 omrader og anvendelser derav

Info

Publication number
NO20083171L
NO20083171L NO20083171A NO20083171A NO20083171L NO 20083171 L NO20083171 L NO 20083171L NO 20083171 A NO20083171 A NO 20083171A NO 20083171 A NO20083171 A NO 20083171A NO 20083171 L NO20083171 L NO 20083171L
Authority
NO
Norway
Prior art keywords
hcdr3
collection
present
members
antibody
Prior art date
Application number
NO20083171A
Other languages
English (en)
Norwegian (no)
Inventor
Christine Rothe
Markus Enzelberger
Stefanie Thiel
Josef Prassler
Stefanie Urlinger
Original Assignee
Morphosys Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphosys Ag filed Critical Morphosys Ag
Publication of NO20083171L publication Critical patent/NO20083171L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO20083171A 2005-12-20 2008-07-18 Ny samling av HCDR3 omrader og anvendelser derav NO20083171L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75163305P 2005-12-20 2005-12-20
PCT/IB2006/004301 WO2008053275A2 (en) 2005-12-20 2006-12-15 Novel collection of hcdr3 regions and uses therefor

Publications (1)

Publication Number Publication Date
NO20083171L true NO20083171L (no) 2008-08-27

Family

ID=39273832

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083171A NO20083171L (no) 2005-12-20 2008-07-18 Ny samling av HCDR3 omrader og anvendelser derav

Country Status (15)

Country Link
US (1) US8273688B2 (ko)
EP (1) EP1979378B1 (ko)
JP (1) JP5405831B2 (ko)
KR (1) KR20080080653A (ko)
CN (1) CN101389655B (ko)
AU (1) AU2006350452B2 (ko)
CA (1) CA2634387C (ko)
DK (1) DK1979378T3 (ko)
ES (1) ES2394722T3 (ko)
IL (1) IL192315A0 (ko)
MX (1) MX2008008220A (ko)
NO (1) NO20083171L (ko)
NZ (1) NZ569359A (ko)
WO (1) WO2008053275A2 (ko)
ZA (1) ZA200806016B (ko)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8288322B2 (en) 2000-04-17 2012-10-16 Dyax Corp. Methods of constructing libraries comprising displayed and/or expressed members of a diverse family of peptides, polypeptides or proteins and the novel libraries
US20030133939A1 (en) * 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US7829084B2 (en) * 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US20040067532A1 (en) 2002-08-12 2004-04-08 Genetastix Corporation High throughput generation and affinity maturation of humanized antibody
SI1912675T1 (sl) * 2005-07-25 2014-07-31 Emergent Product Development Seattle, Llc zmanjšanje števila celic B z uporabo molekul, ki se specifično vežejo na CD37 in CD20
MX363905B (es) * 2006-06-12 2019-04-08 Aptevo Res & Development Llc Proteinas de union multivalentes monocatenarias con funcion efectora.
BRPI0816785A2 (pt) 2007-09-14 2017-05-02 Adimab Inc bibliotecas de anticorpos sintéticos racionalmente desenhadas, e, usos para as mesmas
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
EP2098536A1 (en) 2008-03-05 2009-09-09 4-Antibody AG Isolation and identification of antigen- or ligand-specific binding proteins
US9873957B2 (en) * 2008-03-13 2018-01-23 Dyax Corp. Libraries of genetic packages comprising novel HC CDR3 designs
EP2132228B1 (en) 2008-04-11 2011-06-22 Emergent Product Development Seattle, LLC Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
WO2009132287A2 (en) 2008-04-24 2009-10-29 Dyax Corp. Libraries of genetic packages comprising novel hc cdr1, cdr2, and cdr3 and novel lc cdr1, cdr2, and cdr3 designs
CN102449149B (zh) 2009-05-29 2014-04-23 莫佛塞斯公司 集合及其使用方法
AU2010291902A1 (en) * 2009-09-14 2012-04-05 Dyax Corp. Libraries of genetic packages comprising novel HC CDR3 designs
MX360336B (es) 2010-07-16 2018-10-30 Adimab Llc Star Colecciones de anticuerpos.
JP6253986B2 (ja) 2010-11-19 2017-12-27 モルフォシス・アーゲー コレクション及びその使用方法
WO2017053469A2 (en) 2015-09-21 2017-03-30 Aptevo Research And Development Llc Cd3 binding polypeptides
CN105274630A (zh) * 2015-11-25 2016-01-27 苏州泓迅生物科技有限公司 基于组合合成技术合成可控的人源化抗体库的方法与应用
EP3405486A1 (en) * 2016-01-19 2018-11-28 Zumutor Biologics, Inc. A method of generating a synthetic antibody library, said library and application(s) thereof
EP3293293A1 (en) * 2016-09-08 2018-03-14 Italfarmaco SpA Hc-cdr3-only libraries with reduced combinatorial redundancy and optimized loop length distribution

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6706484B1 (en) * 1995-08-18 2004-03-16 Morphosys Ag Protein/(poly)peptide libraries
WO1997008320A1 (en) * 1995-08-18 1997-03-06 Morphosys Gesellschaft Für Proteinoptimierung Mbh Protein/(poly)peptide libraries
EP1990409A3 (en) * 1999-07-20 2011-05-18 MorphoSys AG Bacteriophage
ES2430857T3 (es) * 2000-12-18 2013-11-22 Dyax Corp. Bibliotecas focalizadas de paquetes genéticos

Also Published As

Publication number Publication date
WO2008053275A2 (en) 2008-05-08
IL192315A0 (en) 2008-12-29
JP5405831B2 (ja) 2014-02-05
ZA200806016B (en) 2009-07-29
CA2634387C (en) 2015-11-24
EP1979378B1 (en) 2012-07-25
AU2006350452B2 (en) 2012-10-25
CN101389655A (zh) 2009-03-18
WO2008053275A3 (en) 2008-08-21
EP1979378A2 (en) 2008-10-15
NZ569359A (en) 2011-11-25
MX2008008220A (es) 2009-03-04
DK1979378T3 (da) 2012-10-29
US20090088346A1 (en) 2009-04-02
KR20080080653A (ko) 2008-09-04
CN101389655B (zh) 2013-05-22
CA2634387A1 (en) 2008-05-08
JP2009519727A (ja) 2009-05-21
US8273688B2 (en) 2012-09-25
AU2006350452A1 (en) 2008-05-08
ES2394722T3 (es) 2013-02-05

Similar Documents

Publication Publication Date Title
NO20083171L (no) Ny samling av HCDR3 omrader og anvendelser derav
Saeed et al. Antibody engineering for pursuing a healthier future
EP3202786A3 (en) Sequence based engineering and optimization of single chain antibodies
UA99701C2 (ru) Человеческое моноклональное антитело, которое специфически связывается с лигандом-1 запрограммированной гибели клеток (pd-l1)
WO2009000098A3 (en) Sequence based engineering and optimization of single chain antibodies
CN106605228B (zh) 计算蛋白质设计的方法
WO2007067730A3 (en) Human monoclonal antibodies to protein tyrosine kinase 7 ( ptk7 ) and their use
NZ717429A (en) Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
WO2007067992A3 (en) Human monoclonal antibodies to fucosyl-gm1 and methods for using anti-fucosyl-gm1
WO2008076560A3 (en) Human monoclonal antibodies to btla and methods of use
Mersmann et al. Towards proteome scale antibody selections using phage display
EP2439273A3 (en) Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics
EA200700917A1 (ru) Способ рефолдинга рекомбинантных антител
EP1994142A4 (en) METHODS AND COMPOSITIONS FOR RAPID ISOLATION OF SMALL RNA MOLECULES
WO2006068975A3 (en) Binding proteins specific for human matriptase
Zumrut et al. Ligand-guided selection with artificially expanded genetic information systems against TCR-CD3ε
WO2001096373A3 (en) Fluorescent timer proteins and methods for their use
WO2004102198A3 (en) Selection of b cells with specificity of interest: method of preparation and use
WO2006073971A3 (en) Binding protein with a scaffold for varying specificity
Stutz et al. Coupling brain perfusion screens and next generation sequencing to identify blood–brain barrier binding antibodies
WO2004113574A3 (en) Methods for disease screening
WO2003027681A3 (en) A method of protein analysis
WO2004069860A3 (en) Isg15-conjugated proteins
WO2002044409A3 (en) Substrate linked directed evolution (slide)
WO2004087759A3 (en) Method and compositions for conversion of antibody activity

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application