NO20083151L - Fast dispersjon omfattende en aktiv bestanddel med et lavt smeltepunkt, og tablett for oral administrering omfattende samme - Google Patents

Fast dispersjon omfattende en aktiv bestanddel med et lavt smeltepunkt, og tablett for oral administrering omfattende samme

Info

Publication number
NO20083151L
NO20083151L NO20083151A NO20083151A NO20083151L NO 20083151 L NO20083151 L NO 20083151L NO 20083151 A NO20083151 A NO 20083151A NO 20083151 A NO20083151 A NO 20083151A NO 20083151 L NO20083151 L NO 20083151L
Authority
NO
Norway
Prior art keywords
solid dispersion
active ingredient
melting point
same
oral administration
Prior art date
Application number
NO20083151A
Other languages
English (en)
Other versions
NO339674B1 (no
Inventor
Jong-Soo Woo
Sang Wook Kim
Hong Gi Yi
Jae Kuk Ryu
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of NO20083151L publication Critical patent/NO20083151L/no
Publication of NO339674B1 publication Critical patent/NO339674B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

En smeltet, fast dispersjon omfattende en aktiv bestanddel som har et smeltepunkt på 80 °C eller lavere og en farmasøytisk akseptabel absorbent som har et spesifikt overfiateareal varierende fra 20 til 400 m/g kan hensiktsmessig sammenpresses til en tablett uten utvikling av overdekkings- og klebeproblemer, og en tablett omfattende angitte smeltede, faste dispersjon kan opprettholde en jevn frigivelsesgrad over en forlenget tid når den administreres oralt.
NO20083151A 2005-12-16 2008-07-15 Fremgangsmåte for fremstilling av en tablett for oral administrering av ibuprofen, dexibuprofen (S(+)-ibuprofen) eller en blanding derav NO339674B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20050124386 2005-12-16
PCT/KR2006/005526 WO2007069874A1 (en) 2005-12-16 2006-12-18 Solid dispersion comprising an active ingredient having a low melting point and tablet for oral administration comprising same

Publications (2)

Publication Number Publication Date
NO20083151L true NO20083151L (no) 2008-09-05
NO339674B1 NO339674B1 (no) 2017-01-23

Family

ID=38163142

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083151A NO339674B1 (no) 2005-12-16 2008-07-15 Fremgangsmåte for fremstilling av en tablett for oral administrering av ibuprofen, dexibuprofen (S(+)-ibuprofen) eller en blanding derav

Country Status (15)

Country Link
US (1) US20080292702A1 (no)
EP (1) EP1968542B1 (no)
JP (1) JP2009519326A (no)
CN (1) CN101330904B (no)
AU (1) AU2006325658B2 (no)
BR (1) BRPI0619868A8 (no)
CA (1) CA2633266C (no)
ES (1) ES2429097T3 (no)
HK (1) HK1126671A1 (no)
IL (1) IL191804A0 (no)
NO (1) NO339674B1 (no)
NZ (1) NZ569813A (no)
RU (1) RU2403013C2 (no)
WO (1) WO2007069874A1 (no)
ZA (1) ZA200806138B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2537837A1 (en) 2003-09-11 2005-03-24 Xenoport, Inc. Treating and/or preventing urinary incontinence using prodrugs of gaba analogs
KR101067224B1 (ko) * 2008-07-22 2011-09-22 한국콜마 주식회사 이부프로펜 함유 서방출성 시럽제 및 그의 제조방법
KR101005391B1 (ko) * 2008-07-22 2010-12-30 한국콜마 주식회사 덱시부프로펜 함유 서방출성 시럽제 및 그의 제조방법
CN101961306B (zh) * 2009-07-24 2011-11-09 北京化工大学 一种低熔点药物固体分散体的制备方法
CN102144982B (zh) * 2011-03-30 2012-12-12 江苏神龙药业有限公司 一种米诺膦酸片及其制备方法
CN102406940B (zh) * 2011-11-01 2013-07-03 温州大学 一种纳米级片状羧甲基淀粉钠在固体分散体中的应用
WO2013154511A1 (en) * 2012-04-13 2013-10-17 Mahmut Bilgic Film tablet formulations comprising dexibuprofen
UY36046A (es) 2014-03-26 2015-10-30 Millennium Pharm Inc Formulaciones farmacéuticas, procesos para la preparación y métodos de uso
JP6647902B2 (ja) * 2015-10-30 2020-02-14 株式会社ファンケル 徐放性顆粒剤
CN106265522A (zh) * 2016-08-30 2017-01-04 铜陵翔宇商贸有限公司 布洛芬‑pvp共沉淀物及其制备方法
JP7109255B2 (ja) * 2017-05-23 2022-07-29 ライオン株式会社 粉砕物の製造方法及び錠剤の製造方法
JP7147262B2 (ja) 2017-05-23 2022-10-05 大正製薬株式会社 固形製剤
EP3658123A4 (en) * 2017-07-24 2021-04-28 Acryspharm LLC PHARMACEUTICAL COMPOSITIONS WITH HIGH ACTIVE INGREDIENT LOAD
RU2685294C1 (ru) * 2018-05-10 2019-04-17 Общество с ограниченной ответственностью "ДИНОН" (ООО "ДИНОН") Поглотитель, способ его приготовления (варианты) и способ удаления диоксида углерода из газовых смесей
CN112263567B (zh) * 2020-10-19 2022-05-03 南京易亨制药有限公司 一种布洛芬缓释胶囊及制备方法
CN117363320B (zh) * 2023-12-07 2024-02-13 黑龙江省鑫博鑫交通科技有限公司 一种公路用融雪剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56120616A (en) * 1980-02-27 1981-09-22 Kaken Pharmaceut Co Ltd Ibuprofen-containing granule, its preparation, and internal medicine comprising it
GB8601204D0 (en) * 1986-01-18 1986-02-19 Boots Co Plc Therapeutic agents
CH669523A5 (no) * 1986-06-25 1989-03-31 Mepha Ag
US4806359A (en) * 1987-04-22 1989-02-21 Mcneilab, Inc. Iburprofen sustained release matrix and process
DE19509807A1 (de) * 1995-03-21 1996-09-26 Basf Ag Verfahren zur Herstellung von Wirkstoffzubereitungen in Form einer festen Lösung des Wirkstoffs in einer Polymermatrix sowie mit diesem Verfahren hergestellte Wirkstoffzubereitungen
IE80467B1 (en) * 1995-07-03 1998-07-29 Elan Corp Plc Controlled release formulations for poorly soluble drugs
US6391338B1 (en) * 1995-09-07 2002-05-21 Biovail Technologies Ltd. System for rendering substantially non-dissoluble bio-affecting agents bio-available
AU695734B2 (en) * 1996-07-08 1998-08-20 Penwest Pharmaceuticals Co. Sustained release matrix for high-dose insoluble drugs
US6787157B1 (en) * 1998-03-10 2004-09-07 Abbott Laboratories Multiphase active ingredient-containing formulations
US6183779B1 (en) * 1999-03-22 2001-02-06 Pharmascience Inc. Stabilized pharmaceutical composition of a nonsteroidal anti-inflammatory agent and a prostaglandin
ES2263510T3 (es) * 1999-12-09 2006-12-16 Reckitt Benckiser Healthcare (Uk) Limited Preparacion en comprimidos que comprende un antiinflamatorio no esteroideo (aine).
GB0113839D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents

Also Published As

Publication number Publication date
EP1968542A4 (en) 2010-06-02
RU2008129041A (ru) 2010-01-27
NZ569813A (en) 2011-07-29
CN101330904B (zh) 2012-04-18
WO2007069874A1 (en) 2007-06-21
NO339674B1 (no) 2017-01-23
HK1126671A1 (en) 2009-09-11
AU2006325658A1 (en) 2007-06-21
IL191804A0 (en) 2008-12-29
EP1968542B1 (en) 2013-08-14
CA2633266A1 (en) 2007-06-21
JP2009519326A (ja) 2009-05-14
CN101330904A (zh) 2008-12-24
US20080292702A1 (en) 2008-11-27
CA2633266C (en) 2011-08-02
ES2429097T3 (es) 2013-11-13
ZA200806138B (en) 2009-11-25
EP1968542A1 (en) 2008-09-17
BRPI0619868A2 (pt) 2011-10-25
AU2006325658B2 (en) 2010-04-08
BRPI0619868A8 (pt) 2016-06-07
RU2403013C2 (ru) 2010-11-10

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