NO20082382L - Fremgangsmater for fremstilling av krystallinsk rapamycin og for maling av krystallinitet av rapamycinforbindelser ved anvendelse av differentiell skanning-kalorimetri - Google Patents
Fremgangsmater for fremstilling av krystallinsk rapamycin og for maling av krystallinitet av rapamycinforbindelser ved anvendelse av differentiell skanning-kalorimetriInfo
- Publication number
- NO20082382L NO20082382L NO20082382A NO20082382A NO20082382L NO 20082382 L NO20082382 L NO 20082382L NO 20082382 A NO20082382 A NO 20082382A NO 20082382 A NO20082382 A NO 20082382A NO 20082382 L NO20082382 L NO 20082382L
- Authority
- NO
- Norway
- Prior art keywords
- rapamycin
- methods
- crystallinity
- painting
- differential scanning
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N25/00—Investigating or analyzing materials by the use of thermal means
- G01N25/20—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N25/00—Investigating or analyzing materials by the use of thermal means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N25/00—Investigating or analyzing materials by the use of thermal means
- G01N25/20—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity
- G01N25/48—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity on solution, sorption, or a chemical reaction not involving combustion or catalytic oxidation
- G01N25/4846—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity on solution, sorption, or a chemical reaction not involving combustion or catalytic oxidation for a motionless, e.g. solid sample
- G01N25/4866—Investigating or analyzing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity on solution, sorption, or a chemical reaction not involving combustion or catalytic oxidation for a motionless, e.g. solid sample by using a differential method
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Combustion & Propulsion (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analyzing Materials Using Thermal Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74800505P | 2005-12-07 | 2005-12-07 | |
PCT/US2006/046445 WO2007067566A2 (en) | 2005-12-07 | 2006-12-06 | Methods for preparing crystalline rapamycin and for measuring crystallinity of rapamycin compounds using differential scanning calorimetry |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20082382L true NO20082382L (no) | 2008-09-04 |
Family
ID=38117222
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20082382A NO20082382L (no) | 2005-12-07 | 2008-05-26 | Fremgangsmater for fremstilling av krystallinsk rapamycin og for maling av krystallinitet av rapamycinforbindelser ved anvendelse av differentiell skanning-kalorimetri |
Country Status (17)
Country | Link |
---|---|
US (1) | US20070128731A1 (es) |
EP (1) | EP1957964A2 (es) |
JP (1) | JP2009518648A (es) |
KR (1) | KR20080077147A (es) |
CN (1) | CN101351702A (es) |
AR (1) | AR058283A1 (es) |
AU (1) | AU2006322030A1 (es) |
BR (1) | BRPI0619592A2 (es) |
CA (1) | CA2630786A1 (es) |
CR (1) | CR9985A (es) |
EC (1) | ECSP088519A (es) |
IL (1) | IL191545A0 (es) |
NO (1) | NO20082382L (es) |
PE (1) | PE20071000A1 (es) |
RU (1) | RU2008120712A (es) |
TW (1) | TW200736603A (es) |
WO (1) | WO2007067566A2 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2380006A4 (en) * | 2009-01-21 | 2012-05-16 | Biocon Ltd | PROCESS FOR DETERMINING THE SIROLIMUS STABILITY AND METHOD FOR PRODUCING ITS STABLE FORM |
FR2943539B1 (fr) | 2009-03-31 | 2011-07-22 | Ethypharm Sa | Composition pharmaceutique comprenant un macrolide immunosuppresseur de la famille des limus. |
JP5703419B2 (ja) * | 2011-08-05 | 2015-04-22 | クルーシブル インテレクチュアル プロパティ エルエルシーCrucible Intellectual Property Llc | 非晶質合金の結晶化度を決定するための非破壊的方法 |
US20150139270A1 (en) * | 2012-04-23 | 2015-05-21 | Apple Inc. | Non-destructive determination of volumetric crystallinity of bulk amorphous alloy |
SG11201507406YA (en) * | 2013-03-15 | 2015-10-29 | Biosensors Int Group Ltd | Purification of rapamycin derivatives |
US9439892B2 (en) | 2013-05-16 | 2016-09-13 | Surmodics, Inc. | Macrolide particulates, methods for preparation, and medical devices associated therewith |
WO2014201236A1 (en) * | 2013-06-12 | 2014-12-18 | Surmodics, Inc. | Solvent methods for preparing crystalline macrolide particulates, compositions, and articles containing particulates |
DE102013110294B4 (de) * | 2013-09-18 | 2016-07-07 | Innora Gmbh | Limus-Depot-Formulierung auf Ballonkathetern |
WO2015181826A1 (en) | 2014-05-27 | 2015-12-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Crystalline coating and release of bioactive agents |
CN105116013A (zh) * | 2015-04-23 | 2015-12-02 | 山东农业大学 | 一种确定金属离子对蛋白酶水解大豆分离蛋白影响的方法 |
JP6531488B2 (ja) * | 2015-05-22 | 2019-06-19 | 日産自動車株式会社 | リチウムイオン二次電池の熱履歴検知方法 |
US10098846B2 (en) | 2016-03-31 | 2018-10-16 | Surmodics, Inc. | Drug-containing particulate composition with cationic agent, associated medical devices, and methods for treatment |
US11123459B2 (en) | 2016-12-16 | 2021-09-21 | Surmodics, Inc. | Hydrophobic active agent particle coatings and methods for treatment |
US11629222B2 (en) * | 2019-07-01 | 2023-04-18 | Ethicon, Inc. | Calorimetric crystallization method for evaluation of monomer purity |
WO2023158308A1 (en) | 2022-02-18 | 2023-08-24 | Technische Universiteit Delft | Novel method for analyzing dsc data |
NL2031004B1 (en) * | 2022-02-18 | 2023-09-05 | Univ Delft Tech | Novel method for analyzing DSC data |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA737247B (en) * | 1972-09-29 | 1975-04-30 | Ayerst Mckenna & Harrison | Rapamycin and process of preparation |
US5358909A (en) * | 1991-02-27 | 1994-10-25 | Nippon Steel Corporation | Method of manufacturing field-emitter |
US5358908A (en) * | 1992-02-14 | 1994-10-25 | Micron Technology, Inc. | Method of creating sharp points and other features on the surface of a semiconductor substrate |
GB9313650D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
US5385909A (en) * | 1993-11-22 | 1995-01-31 | American Home Products Corporation | Heterocyclic esters of rapamycin |
US5385908A (en) * | 1993-11-22 | 1995-01-31 | American Home Products Corporation | Hindered esters of rapamycin |
US5362718A (en) * | 1994-04-18 | 1994-11-08 | American Home Products Corporation | Rapamycin hydroxyesters |
EP0884585A3 (de) * | 1997-06-06 | 1999-12-29 | Netzsch Gerätebau GmbH | Vorrichtung zur Differential-Scanning-Kalorimetrie |
GB9826882D0 (en) * | 1998-12-07 | 1999-01-27 | Novartis Ag | Organic compounds |
US6277983B1 (en) * | 2000-09-27 | 2001-08-21 | American Home Products Corporation | Regioselective synthesis of rapamycin derivatives |
ES2177373B1 (es) * | 1999-11-26 | 2003-11-01 | Astur Pharma Sa | Preparacion de azitromicina en su forma no cristalina |
DE60136200D1 (de) * | 2000-09-19 | 2008-11-27 | Wyeth Corp | Wasserlösliche rapamycin-ester |
KR20050037477A (ko) * | 2001-10-17 | 2005-04-22 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 로터-스테이터 장치와 입자 생성을 위한 방법 |
US20060169199A1 (en) * | 2003-03-31 | 2006-08-03 | Vilmos Keri | Crystallization and purification of macrolides |
US7220357B2 (en) * | 2003-07-24 | 2007-05-22 | Teva Gyógyszergyár Zártkörúen Múkó´dó´Résvénytársaság | Method of purifying macrolides |
ATE365169T1 (de) * | 2003-08-07 | 2007-07-15 | Wyeth Corp | Regioselektive synthese von cci-779 |
JP2007504226A (ja) * | 2003-09-03 | 2007-03-01 | ワイス | 非晶質状のラパマイシンの3−ヒドロキシ−2−(ヒドロキシメチル)−2−メチルプロピオン酸との42−エステル、およびそれを含むその医薬組成物 |
BRPI0509810A (pt) * | 2004-04-14 | 2007-09-18 | Wyeth Corp | método para a sìntese regioespecìfica de um 42-hemiéster de rapamicina ou um 32-hemiéster de fk-506 com um ácido dicarboxìlico, 42-hemiéster de rapamicina regioespecìfica, anticorpo de rapamicina, produto, e, 32-hemiéster de fk506 regioespecìfico |
RU2387657C2 (ru) * | 2004-04-14 | 2010-04-27 | Вайет | Региоспецифический синтез производных 42-эфира рапамицина |
EP1776370A1 (en) * | 2004-08-10 | 2007-04-25 | Wyeth a Corporation of the State of Delaware | Cci-779 derivatives and methods of making same |
ES2380779T3 (es) * | 2004-12-20 | 2012-05-18 | Wyeth Llc | Análogos de rapamicina y usos de los mismos en el tratamiento de trastornos neurológicos, proliferativos e inflamatorios |
MX2007007409A (es) * | 2004-12-20 | 2007-07-12 | Wyeth Corp | Derivados de rapamicina y los usos de los mismos en el tratamiento de trastornos neurologicos. |
BRPI0607932A2 (pt) * | 2005-02-09 | 2016-11-08 | Wyeth Corp | polimorfo cci-779, processo para preparar polimorfo cci-779, composição farmacêutica, kit, e método para preparar uma composição farmacêutica |
CN101133066A (zh) * | 2005-03-02 | 2008-02-27 | 惠氏公司 | 从母液中回收cci-779 |
WO2006096325A1 (en) * | 2005-03-07 | 2006-09-14 | Wyeth | Oxepane isomer of 42-o-(2-hydroxy)ethyl-rapamycin |
-
2006
- 2006-12-06 KR KR1020087013406A patent/KR20080077147A/ko not_active Application Discontinuation
- 2006-12-06 CN CNA2006800461020A patent/CN101351702A/zh not_active Withdrawn
- 2006-12-06 EP EP06847503A patent/EP1957964A2/en not_active Withdrawn
- 2006-12-06 TW TW095145393A patent/TW200736603A/zh unknown
- 2006-12-06 WO PCT/US2006/046445 patent/WO2007067566A2/en active Application Filing
- 2006-12-06 CA CA002630786A patent/CA2630786A1/en not_active Abandoned
- 2006-12-06 AU AU2006322030A patent/AU2006322030A1/en not_active Abandoned
- 2006-12-06 AR ARP060105389A patent/AR058283A1/es unknown
- 2006-12-06 RU RU2008120712/28A patent/RU2008120712A/ru not_active Application Discontinuation
- 2006-12-06 JP JP2008544451A patent/JP2009518648A/ja active Pending
- 2006-12-06 US US11/634,694 patent/US20070128731A1/en not_active Abandoned
- 2006-12-06 PE PE2006001569A patent/PE20071000A1/es not_active Application Discontinuation
- 2006-12-06 BR BRPI0619592A patent/BRPI0619592A2/pt not_active IP Right Cessation
-
2008
- 2008-05-19 IL IL191545A patent/IL191545A0/en unknown
- 2008-05-19 CR CR9985A patent/CR9985A/es not_active Application Discontinuation
- 2008-05-26 NO NO20082382A patent/NO20082382L/no not_active Application Discontinuation
- 2008-06-09 EC EC2008008519A patent/ECSP088519A/es unknown
Also Published As
Publication number | Publication date |
---|---|
TW200736603A (en) | 2007-10-01 |
WO2007067566A2 (en) | 2007-06-14 |
AU2006322030A1 (en) | 2007-06-14 |
US20070128731A1 (en) | 2007-06-07 |
AR058283A1 (es) | 2008-01-30 |
CA2630786A1 (en) | 2007-06-14 |
CR9985A (es) | 2008-08-21 |
EP1957964A2 (en) | 2008-08-20 |
KR20080077147A (ko) | 2008-08-21 |
CN101351702A (zh) | 2009-01-21 |
RU2008120712A (ru) | 2010-01-20 |
JP2009518648A (ja) | 2009-05-07 |
PE20071000A1 (es) | 2007-10-10 |
WO2007067566A3 (en) | 2008-01-24 |
BRPI0619592A2 (pt) | 2016-09-06 |
IL191545A0 (en) | 2008-12-29 |
ECSP088519A (es) | 2008-07-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20082382L (no) | Fremgangsmater for fremstilling av krystallinsk rapamycin og for maling av krystallinitet av rapamycinforbindelser ved anvendelse av differentiell skanning-kalorimetri | |
NO20092960L (no) | Krystallinsk minocycline base og framgangsmater for framstilling av denne | |
NO20080784L (no) | Histondeacetylaseinhibitorer | |
AU2006319247A8 (en) | Heteroaryl substituted piperidine derivatives as L-CPT1 inhibitors | |
WO2007136510A3 (en) | Polymorphic forms of imatinib mesylate and processes for their preparation as well as of amorphous imatinib mesylate and form alpha | |
NO20071707L (no) | Fremstilling av 4,5-dihydro-pyrazolo[3,4-C]Pyrid-2-oner | |
DK1695709T3 (da) | Krystalinsk gammad-form af ivabradin-hydrochlorid, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende denne | |
EP1851869A4 (en) | SYSTEM, APPARATUS AND METHOD FOR ADAPTIVE INTERFERENCE-WEIGHTED ADAPTIVE CANCELLATION BY PARALLEL RESIDUE COMPENSATION | |
DK1695965T3 (da) | Krystallinsk betaform af ivabradin-hydrochlorid, fremgangsmåde til fremstilling heraf og famceutiske sammensætninger indeholdende denne | |
AU2003259227A1 (en) | Cellulose support for seed | |
WO2007146622A3 (en) | Molecular sieve ssz-75 composition of matter and synthesis thereof | |
GB2431927A9 (en) | 1,2-Disubstituted indoles & derivatives thereof astherapeutic 5-iipoxygenase-activating protein (fl ap) inhibitors | |
PT1713801E (pt) | Processo para a preparação de 1-(2s,3s)-2-benzidril-n-(5- -terc-butil-2-metoxibenzil)-quinuclidina-3-amina | |
ZA200801890B (en) | Novel crystalline form of a pyridazino (4, 5-B) indole derivative | |
EP1881975B8 (en) | N,n-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors | |
WO2008021342A3 (en) | Amorphous and crystalline forms of 9-hydroxy-risperidone ( paliperidone ) | |
NO20074739L (no) | Amidderivater som ionkanalligander og farmasoytiske sammensetninger og fremgangsmater for anvendelse av samme | |
WO2007012075A3 (en) | Preparation of montelukast | |
NO20091817L (no) | Kinase inhibitorer | |
AU2003234725A1 (en) | High throughput x-ray diffraction filter sample holder | |
WO2005080403A3 (en) | Chemical process | |
NO20071634L (no) | Effektiv syntese av 4,5-dihydro-pyrazolo(3,4-C)pyrid-2-oner | |
NO20070550L (no) | Fremgangsmate for fremstilling av pyrrolotriazinforbindelser | |
TW200708512A (en) | Crystal of aminopyrrolidine derivative and production method thereof | |
DE602007012935D1 (de) | Aminothiazolmakrocyclen, ihre verwendung als antibakterielle verbindungen und verfahren zu ihrer herstellung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |