NO20081523L - Fremstilling og anvendelse av tetrahydropyrrolo(3,2-C)Pyridin-4-on-derivater for behandling av fedme, psykiatriske og neurologiske forstyrrelser - Google Patents
Fremstilling og anvendelse av tetrahydropyrrolo(3,2-C)Pyridin-4-on-derivater for behandling av fedme, psykiatriske og neurologiske forstyrrelserInfo
- Publication number
- NO20081523L NO20081523L NO20081523A NO20081523A NO20081523L NO 20081523 L NO20081523 L NO 20081523L NO 20081523 A NO20081523 A NO 20081523A NO 20081523 A NO20081523 A NO 20081523A NO 20081523 L NO20081523 L NO 20081523L
- Authority
- NO
- Norway
- Prior art keywords
- pyridin
- tetrahydropyrrolo
- psychiatric
- obesity
- preparation
- Prior art date
Links
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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Abstract
Foreliggende oppfinnelse angår 4,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-on- og 4,5-dihydropyrrolo[3,2-c]pyridin-4-on-forbindelser med formel I og fremgangsmåter for fremstilling av slike forbindelser, anvendelse av dem ved behandling av fedme, psykiatriske og nevrologiske lidelser, metoder for deres terapeutiske anvendelse og farmasøytiske preparater inneholdende dem.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72415605P | 2005-10-06 | 2005-10-06 | |
PCT/GB2006/003695 WO2007039740A2 (en) | 2005-10-06 | 2006-10-05 | Preparation and use of tetrahydropyrrolo [3, 2-c] pyridin-4-one derivatives for treatment of obesity, psychiatric and neurological disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20081523L true NO20081523L (no) | 2008-07-02 |
Family
ID=37781800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20081523A NO20081523L (no) | 2005-10-06 | 2008-03-28 | Fremstilling og anvendelse av tetrahydropyrrolo(3,2-C)Pyridin-4-on-derivater for behandling av fedme, psykiatriske og neurologiske forstyrrelser |
Country Status (21)
Country | Link |
---|---|
US (2) | US7875626B2 (no) |
EP (1) | EP1937679B1 (no) |
JP (1) | JP4277062B2 (no) |
KR (1) | KR20080058456A (no) |
CN (1) | CN101277957A (no) |
AR (1) | AR056560A1 (no) |
AT (1) | ATE440099T1 (no) |
AU (1) | AU2006298530B2 (no) |
BR (1) | BRPI0616653A2 (no) |
CA (1) | CA2624495A1 (no) |
DE (1) | DE602006008641D1 (no) |
EC (1) | ECSP088413A (no) |
ES (1) | ES2329616T3 (no) |
HK (1) | HK1122808A1 (no) |
IL (1) | IL190025A0 (no) |
NO (1) | NO20081523L (no) |
RU (1) | RU2415856C2 (no) |
TW (1) | TW200730525A (no) |
UY (1) | UY29838A1 (no) |
WO (1) | WO2007039740A2 (no) |
ZA (1) | ZA200802946B (no) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR056560A1 (es) * | 2005-10-06 | 2007-10-10 | Astrazeneca Ab | Pirrolopiridinonas como moduladores cb1 |
PT1973910E (pt) * | 2006-01-27 | 2013-09-06 | Shanghai Hengrui Pharm Co Ltd | Inibidores de pirrolo [3,2-c] piridina-4-ona 2-indolinona proteína cinase |
AU2007283113A1 (en) | 2006-08-08 | 2008-02-14 | Sanofi-Aventis | Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, processes for preparing them, medicaments comprising these compounds, and their use |
AR065909A1 (es) * | 2007-04-03 | 2009-07-08 | Astrazeneca Ab | Agentes terapeuticos 685 |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
GEP20125664B (en) * | 2008-02-26 | 2012-10-10 | Takeda Pharmaceuticals Co | Condensed heterocyclic derivatives and application thereof |
UY31968A (es) | 2008-07-09 | 2010-01-29 | Sanofi Aventis | Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos |
WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
US20110015154A1 (en) * | 2009-07-20 | 2011-01-20 | Kellermann Gottfried H | Supporting acetylcholine function |
CA2771278A1 (en) | 2009-08-26 | 2011-03-03 | Sanofi | Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use |
US20110098265A1 (en) * | 2009-10-28 | 2011-04-28 | Neuroscience, Inc. | Methods for reducing cravings and impulses associated with addictive and compulsive behaviors |
EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
KR101273643B1 (ko) * | 2010-10-12 | 2013-06-11 | 한국화학연구원 | 5,6-디하이드로-피롤로[3,4-b]피리딘-7-온 유도체 또는 이의 약학적으로 허용 가능한 염, 이의 제조방법 및 이를 유효성분으로 포함하는 약학적 조성물 |
WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
WO2012120053A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
US8828994B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
US9560630B2 (en) * | 2011-08-12 | 2017-01-31 | Qualcomm Incorporated | Devices for reduced overhead paging |
UY35370A (es) | 2013-03-06 | 2014-09-30 | Janssen Pharmaceutica Nv | Moduladores benzoimidazol-2-il pirimidina del receptor de histamina h4 |
UA122221C2 (uk) | 2015-01-28 | 2020-10-12 | Байєр Фарма Акцієнгезелльшафт | 4Н-ПІРОЛО[3,2-c]ПІРИДИН-4-ОНОВІ ПОХІДНІ |
WO2020074403A1 (en) * | 2018-10-08 | 2020-04-16 | Universität Zürich | Appetite-modulating molecules |
US20230046077A1 (en) | 2019-02-07 | 2023-02-16 | Bayer Aktiengesellschaft | 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as csnk1 inhibitors |
US20210015762A1 (en) * | 2019-07-16 | 2021-01-21 | TRUETIVA, Inc. | Compositions for treating obesity |
KR20210103688A (ko) | 2020-02-14 | 2021-08-24 | (주) 디엔테크 | 오링용 고무조성물 |
EP4188929A1 (en) | 2020-07-29 | 2023-06-07 | Bayer Aktiengesellschaft | Substituted pyrrolo-pyridinone derivatives and therapeutic uses thereof |
EP4188551A1 (en) | 2020-07-29 | 2023-06-07 | Bayer Aktiengesellschaft | Aryl substituted pyrrolo-pyridinones and therapeutic uses thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2692575B1 (fr) * | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
FR2714057B1 (fr) * | 1993-12-17 | 1996-03-08 | Sanofi Elf | Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant. |
FR2758723B1 (fr) * | 1997-01-28 | 1999-04-23 | Sanofi Sa | Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour la preparation de medicaments |
US6858616B2 (en) * | 1998-12-23 | 2005-02-22 | Bristol-Myers Squibb Pharma Company | Nitrogen containing heterobicycles as factor Xa inhibitors |
UA74367C2 (uk) | 2000-03-23 | 2005-12-15 | Сольве Фармас'Ютікалз Б.В. | ПОХІДНІ 4,5-ДИГІДРО-1Н-ПІРАЗОЛУ, ЩО ВИЯВЛЯЮТЬ АНТАГОНІСТИЧНУ АКТИВНІСТЬ ЩОДО СВ<sub>1</sub>, СПОСІБ ЇХ ОДЕРЖАННЯ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ТА СПОСІБ ЇЇ ВИГОТОВЛЕННЯ, СПОСІБ ЛІКУВАННЯ ЗАХВОРЮВАНЬ (ВАРІАНТИ) |
MXPA04002249A (es) * | 2001-09-24 | 2004-06-29 | Bayer Pharmaceuticals Corp | Preparacion y uso de derivados de 1,5,6,7,-tetrahidro-pirrolo[3,2-c]piridina para el tratamiento de la obesidad. |
CA2555331C (en) | 2004-02-20 | 2011-01-04 | Astrazeneca Ab | Therapeutic agents |
GB0403780D0 (en) | 2004-02-20 | 2004-03-24 | Astrazeneca Ab | Therapeutic agents |
CA2560417C (en) | 2004-04-03 | 2011-04-19 | Astrazeneca Ab | 1,2-diarylimidazole-4-carboxamide derivatives |
AR056560A1 (es) * | 2005-10-06 | 2007-10-10 | Astrazeneca Ab | Pirrolopiridinonas como moduladores cb1 |
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US7875626B2 (en) | 2011-01-25 |
TW200730525A (en) | 2007-08-16 |
US20080312269A1 (en) | 2008-12-18 |
BRPI0616653A2 (pt) | 2011-06-28 |
ZA200802946B (en) | 2009-03-25 |
IL190025A0 (en) | 2008-08-07 |
US20080009513A1 (en) | 2008-01-10 |
EP1937679B1 (en) | 2009-08-19 |
ECSP088413A (es) | 2008-05-30 |
KR20080058456A (ko) | 2008-06-25 |
AU2006298530B2 (en) | 2009-10-29 |
EP1937679A2 (en) | 2008-07-02 |
UY29838A1 (es) | 2007-05-31 |
RU2008109185A (ru) | 2009-11-20 |
CA2624495A1 (en) | 2007-04-12 |
CN101277957A (zh) | 2008-10-01 |
WO2007039740A3 (en) | 2007-05-31 |
ES2329616T3 (es) | 2009-11-27 |
US7576095B2 (en) | 2009-08-18 |
RU2415856C2 (ru) | 2011-04-10 |
HK1122808A1 (en) | 2009-05-29 |
AU2006298530A1 (en) | 2007-04-12 |
DE602006008641D1 (de) | 2009-10-01 |
ATE440099T1 (de) | 2009-09-15 |
JP4277062B2 (ja) | 2009-06-10 |
JP2009504722A (ja) | 2009-02-05 |
WO2007039740A2 (en) | 2007-04-12 |
AR056560A1 (es) | 2007-10-10 |
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