ATE440099T1 - Herstellung und anwendung von tetrahydropyrrolo ä3, 2-cüpyridin-4-onderivaten zur behandlung von obesitas und psychiatrischen und neurologischen erkrankungen - Google Patents
Herstellung und anwendung von tetrahydropyrrolo ä3, 2-cüpyridin-4-onderivaten zur behandlung von obesitas und psychiatrischen und neurologischen erkrankungenInfo
- Publication number
- ATE440099T1 ATE440099T1 AT06794647T AT06794647T ATE440099T1 AT E440099 T1 ATE440099 T1 AT E440099T1 AT 06794647 T AT06794647 T AT 06794647T AT 06794647 T AT06794647 T AT 06794647T AT E440099 T1 ATE440099 T1 AT E440099T1
- Authority
- AT
- Austria
- Prior art keywords
- cüpyridine
- tetrahydropyrrolo
- psychiatric
- obesity
- derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72415605P | 2005-10-06 | 2005-10-06 | |
PCT/GB2006/003695 WO2007039740A2 (en) | 2005-10-06 | 2006-10-05 | Preparation and use of tetrahydropyrrolo [3, 2-c] pyridin-4-one derivatives for treatment of obesity, psychiatric and neurological disorders |
Publications (1)
Publication Number | Publication Date |
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ATE440099T1 true ATE440099T1 (de) | 2009-09-15 |
Family
ID=37781800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06794647T ATE440099T1 (de) | 2005-10-06 | 2006-10-05 | Herstellung und anwendung von tetrahydropyrrolo ä3, 2-cüpyridin-4-onderivaten zur behandlung von obesitas und psychiatrischen und neurologischen erkrankungen |
Country Status (21)
Country | Link |
---|---|
US (2) | US7875626B2 (de) |
EP (1) | EP1937679B1 (de) |
JP (1) | JP4277062B2 (de) |
KR (1) | KR20080058456A (de) |
CN (1) | CN101277957A (de) |
AR (1) | AR056560A1 (de) |
AT (1) | ATE440099T1 (de) |
AU (1) | AU2006298530B2 (de) |
BR (1) | BRPI0616653A2 (de) |
CA (1) | CA2624495A1 (de) |
DE (1) | DE602006008641D1 (de) |
EC (1) | ECSP088413A (de) |
ES (1) | ES2329616T3 (de) |
HK (1) | HK1122808A1 (de) |
IL (1) | IL190025A0 (de) |
NO (1) | NO20081523L (de) |
RU (1) | RU2415856C2 (de) |
TW (1) | TW200730525A (de) |
UY (1) | UY29838A1 (de) |
WO (1) | WO2007039740A2 (de) |
ZA (1) | ZA200802946B (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR056560A1 (es) * | 2005-10-06 | 2007-10-10 | Astrazeneca Ab | Pirrolopiridinonas como moduladores cb1 |
ES2426448T3 (es) * | 2006-01-27 | 2013-10-23 | Shanghai Hengrui Pharmaceutical Co. Ltd. | Inhibidores de proteína quinasa de pirrolo[3,2-c]piridin-4-ona 2-indolinona |
JP2010500300A (ja) | 2006-08-08 | 2010-01-07 | サノフィ−アベンティス | アリールアミノアリール−アルキル−置換イミダゾリジン−2,4−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用 |
AR065909A1 (es) * | 2007-04-03 | 2009-07-08 | Astrazeneca Ab | Agentes terapeuticos 685 |
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
AU2009217982B2 (en) * | 2008-02-26 | 2013-04-11 | Takeda Pharmaceutical Company Limited | Fused heterocyclic derivative and use thereof |
EP2310372B1 (de) | 2008-07-09 | 2012-05-23 | Sanofi | Heterocyclische Verbindungen, Verfahren zu ihrer Herstellung, Arzneimitteln mit diesen Verbindungen und ihre Verwendung |
WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
US20110015154A1 (en) * | 2009-07-20 | 2011-01-20 | Kellermann Gottfried H | Supporting acetylcholine function |
US8785608B2 (en) | 2009-08-26 | 2014-07-22 | Sanofi | Crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use |
US20110098265A1 (en) * | 2009-10-28 | 2011-04-28 | Neuroscience, Inc. | Methods for reducing cravings and impulses associated with addictive and compulsive behaviors |
WO2011157827A1 (de) | 2010-06-18 | 2011-12-22 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
KR101273643B1 (ko) * | 2010-10-12 | 2013-06-11 | 한국화학연구원 | 5,6-디하이드로-피롤로[3,4-b]피리딘-7-온 유도체 또는 이의 약학적으로 허용 가능한 염, 이의 제조방법 및 이를 유효성분으로 포함하는 약학적 조성물 |
EP2683700B1 (de) | 2011-03-08 | 2015-02-18 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
US8710050B2 (en) | 2011-03-08 | 2014-04-29 | Sanofi | Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US9560630B2 (en) * | 2011-08-12 | 2017-01-31 | Qualcomm Incorporated | Devices for reduced overhead paging |
DK2964229T3 (da) | 2013-03-06 | 2020-01-27 | Janssen Pharmaceutica Nv | Benzoimidazol-2-yl-pyrimidinmodulatorer af histamin-h4 receptoren |
TN2017000329A1 (en) | 2015-01-28 | 2019-01-16 | Bayer Pharma AG | 4h-pyrrolo[3,2-c]pyridin-4-one derivatives |
WO2020074403A1 (en) * | 2018-10-08 | 2020-04-16 | Universität Zürich | Appetite-modulating molecules |
CA3128946A1 (en) | 2019-02-07 | 2020-08-13 | Bayer Aktiengesellschaft | 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as csnk1 inhibitors |
US20210015762A1 (en) * | 2019-07-16 | 2021-01-21 | TRUETIVA, Inc. | Compositions for treating obesity |
KR20210103688A (ko) | 2020-02-14 | 2021-08-24 | (주) 디엔테크 | 오링용 고무조성물 |
US20230322767A1 (en) | 2020-07-29 | 2023-10-12 | Bayer Aktiengesellschaft | Aryl substituted pyrrolo-pyridinones and therapeutic uses thereof |
US20230365554A1 (en) | 2020-07-29 | 2023-11-16 | The Broad Institute, Inc. | Substituted pyrrolo-pyridinone derivatives and therapeutic uses thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2692575B1 (fr) | 1992-06-23 | 1995-06-30 | Sanofi Elf | Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
FR2714057B1 (fr) | 1993-12-17 | 1996-03-08 | Sanofi Elf | Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant. |
FR2758723B1 (fr) | 1997-01-28 | 1999-04-23 | Sanofi Sa | Utilisation des antagonistes des recepteurs aux cannabinoides centraux pour la preparation de medicaments |
US6858616B2 (en) | 1998-12-23 | 2005-02-22 | Bristol-Myers Squibb Pharma Company | Nitrogen containing heterobicycles as factor Xa inhibitors |
ATE346047T1 (de) | 2000-03-23 | 2006-12-15 | Solvay Pharm Bv | 4,5-dihydro-1h-pyrazolderivate mit cb1- antagonistischer aktivität |
ATE311386T1 (de) * | 2001-09-24 | 2005-12-15 | Bayer Pharmaceuticals Corp | Verfahren zur herstellung von 1,5,6,7- tetrahydropyrrolo(3,2-c)derivaten zur behandlung der fettleibigkeit |
DE602005016082D1 (de) | 2004-02-20 | 2009-10-01 | Astrazeneca Ab | 3-substituierte 1,5-diphenylpyrazolderivate, die sich als cb1-modulatoren eignen |
GB0403780D0 (en) | 2004-02-20 | 2004-03-24 | Astrazeneca Ab | Therapeutic agents |
US7799804B2 (en) | 2004-04-03 | 2010-09-21 | Astrazeneca Ab | Therapeutic agents |
AR056560A1 (es) * | 2005-10-06 | 2007-10-10 | Astrazeneca Ab | Pirrolopiridinonas como moduladores cb1 |
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- 2006-10-05 CA CA002624495A patent/CA2624495A1/en not_active Abandoned
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Also Published As
Publication number | Publication date |
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ZA200802946B (en) | 2009-03-25 |
HK1122808A1 (en) | 2009-05-29 |
AR056560A1 (es) | 2007-10-10 |
IL190025A0 (en) | 2008-08-07 |
ECSP088413A (es) | 2008-05-30 |
NO20081523L (no) | 2008-07-02 |
TW200730525A (en) | 2007-08-16 |
US7875626B2 (en) | 2011-01-25 |
RU2008109185A (ru) | 2009-11-20 |
RU2415856C2 (ru) | 2011-04-10 |
CA2624495A1 (en) | 2007-04-12 |
CN101277957A (zh) | 2008-10-01 |
WO2007039740A2 (en) | 2007-04-12 |
US7576095B2 (en) | 2009-08-18 |
BRPI0616653A2 (pt) | 2011-06-28 |
EP1937679A2 (de) | 2008-07-02 |
US20080312269A1 (en) | 2008-12-18 |
UY29838A1 (es) | 2007-05-31 |
JP2009504722A (ja) | 2009-02-05 |
AU2006298530B2 (en) | 2009-10-29 |
AU2006298530A1 (en) | 2007-04-12 |
WO2007039740A3 (en) | 2007-05-31 |
US20080009513A1 (en) | 2008-01-10 |
KR20080058456A (ko) | 2008-06-25 |
EP1937679B1 (de) | 2009-08-19 |
ES2329616T3 (es) | 2009-11-27 |
DE602006008641D1 (de) | 2009-10-01 |
JP4277062B2 (ja) | 2009-06-10 |
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