NO20080725L - Konserverende sammensetning for oftalmisk anvendelse - Google Patents
Konserverende sammensetning for oftalmisk anvendelseInfo
- Publication number
- NO20080725L NO20080725L NO20080725A NO20080725A NO20080725L NO 20080725 L NO20080725 L NO 20080725L NO 20080725 A NO20080725 A NO 20080725A NO 20080725 A NO20080725 A NO 20080725A NO 20080725 L NO20080725 L NO 20080725L
- Authority
- NO
- Norway
- Prior art keywords
- ophthalmic use
- preservative composition
- chlorite
- generation
- prevent
- Prior art date
Links
- 230000002335 preservative effect Effects 0.000 title abstract 3
- 239000003755 preservative agent Substances 0.000 title abstract 2
- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 abstract 4
- 239000004155 Chlorine dioxide Substances 0.000 abstract 2
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 abstract 2
- 235000019398 chlorine dioxide Nutrition 0.000 abstract 2
- 229910001919 chlorite Inorganic materials 0.000 abstract 2
- 229910052619 chlorite group Inorganic materials 0.000 abstract 2
- QBWCMBCROVPCKQ-UHFFFAOYSA-N chlorous acid Chemical compound OCl=O QBWCMBCROVPCKQ-UHFFFAOYSA-N 0.000 abstract 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 abstract 1
- GLZPCOQZEFWAFX-YFHOEESVSA-N Geraniol Natural products CC(C)=CCC\C(C)=C/CO GLZPCOQZEFWAFX-YFHOEESVSA-N 0.000 abstract 1
- 239000005792 Geraniol Substances 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- YYVFXSYQSOZCOQ-UHFFFAOYSA-N Oxyquinoline sulfate Chemical compound [O-]S([O-])(=O)=O.C1=C[NH+]=C2C(O)=CC=CC2=C1.C1=C[NH+]=C2C(O)=CC=CC2=C1 YYVFXSYQSOZCOQ-UHFFFAOYSA-N 0.000 abstract 1
- 229920001214 Polysorbate 60 Polymers 0.000 abstract 1
- 229940109239 creatinine Drugs 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- -1 fatty acid ester Chemical class 0.000 abstract 1
- 229940113087 geraniol Drugs 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 229960001257 oxyquinoline sulfate Drugs 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 150000005846 sugar alcohols Chemical class 0.000 abstract 1
- 229940042585 tocopherol acetate Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Hensikten med foreliggende oppfinnelse er å forhindre genereringen av klordioksid i et flytende preparat for oftalmisk anvendelse ved anvendelse av et kloritt. Et flytende preparat for oftalmisk anvendelse anvendes inneholdende en konserveringsmiddelsammensetning for oftalmisk anvendelse omfattende et kloritt og minst et stabiliseringsmiddel valgt fra de følgende 1) til 7): 1) kreatinin; 2) geraniol; 3) glukose; 4) tokoferolacetat; 5) oksykinolinsulfat; 6) en sukkeralkohol; og 7) en polyoksyetylensorbitanfettsyreester. Dette preparatet kan forhindre genereringen av klordioksid, og er derfor utmerket med hensyn til sikkerhet og viser en forlenget konserverende effekt i et utvidet tidsrom.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005204472 | 2005-07-13 | ||
| PCT/JP2006/313944 WO2007007832A1 (ja) | 2005-07-13 | 2006-07-13 | 眼科用防腐組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20080725L true NO20080725L (no) | 2008-02-15 |
| NO339109B1 NO339109B1 (no) | 2016-11-14 |
Family
ID=37637214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20080725A NO339109B1 (no) | 2005-07-13 | 2008-02-08 | Konserverende sammensetning for oftalmisk anvendelse |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080269353A1 (no) |
| EP (1) | EP1905453B1 (no) |
| KR (1) | KR101354892B1 (no) |
| CN (1) | CN101222939B (no) |
| CA (1) | CA2615108A1 (no) |
| DK (1) | DK1905453T3 (no) |
| ES (1) | ES2393675T3 (no) |
| NO (1) | NO339109B1 (no) |
| PL (1) | PL1905453T3 (no) |
| PT (1) | PT1905453E (no) |
| RU (1) | RU2413534C2 (no) |
| WO (1) | WO2007007832A1 (no) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2127638A1 (en) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
| US20100233101A1 (en) | 2009-02-13 | 2010-09-16 | Micropure, Inc. | Composition and method for the oxidative consumption of salivary biomolecules |
| DE102010055771A1 (de) * | 2010-12-23 | 2012-06-28 | KyroChem GmbH | Chlorithaltige Zusammensetzung |
| JP6449774B2 (ja) * | 2013-09-17 | 2019-01-09 | 千寿製薬株式会社 | 両性イオン性ソフトコンタクトレンズ用眼科用組成物 |
| RU2677665C2 (ru) * | 2013-09-17 | 2019-01-18 | Сэндзю Фармасьютикал Ко., Лтд. | Офтальмическая композиция для анионных мягких контактных линз |
| RU2528912C1 (ru) * | 2013-10-09 | 2014-09-20 | Станислав Анатольевич Кедик | Глазные капли на основе композиции фармацевтически приемлемой аддитивной соли кислоты и метилэтилпиридинола, содержащие композицию витаминов группы в |
| CA3020197C (en) | 2017-09-01 | 2024-06-04 | Micropure, Inc. | Aliphatic anionic compounds and oxidative compounds with improved stability and efficacy for use in pharmaceutical compositions |
| US11096958B2 (en) | 2018-04-27 | 2021-08-24 | Allergan, Inc. | Sodium chlorite compositions with enhanced anti-microbial efficacy and reduced toxicity |
| EP4176881A1 (en) * | 2020-07-30 | 2023-05-10 | Rohto Pharmaceutical Co., Ltd. | Aqueous composition |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0196075B1 (en) * | 1985-03-26 | 1990-03-14 | Toray Industries, Inc. | Cleaning system for contact lenses and process for cleaning the same |
| ES2199956T3 (es) * | 1992-12-17 | 2004-03-01 | Advanced Medical Optics, Inc. | Solucion desinfectante de lentes de contacto que contiene un agente oxidante y polivinilpirrolidona. |
| US5648074A (en) * | 1993-05-25 | 1997-07-15 | Allergan | Compositions and methods for disinfecting contact lenses and reducing proteinaceous deposit formation |
| US6846478B1 (en) * | 1998-02-27 | 2005-01-25 | The Procter & Gamble Company | Promoting whole body health |
| US6251372B1 (en) * | 1998-02-27 | 2001-06-26 | The Procter & Gamble Company | Oral care compositions comprising chlorite and methods |
| JP2002523475A (ja) * | 1998-09-02 | 2002-07-30 | アラーガン・セイルズ・インコーポレイテッド | 防腐したシクロデキストリン含有組成物 |
| DE60218738T2 (de) * | 2001-12-21 | 2007-12-06 | Senju Pharmaceutical Co., Ltd. | Augentropfen |
| US20050196370A1 (en) * | 2003-03-18 | 2005-09-08 | Zhi-Jian Yu | Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye |
-
2006
- 2006-07-13 DK DK06781064.8T patent/DK1905453T3/da active
- 2006-07-13 WO PCT/JP2006/313944 patent/WO2007007832A1/ja active Application Filing
- 2006-07-13 RU RU2008105323/15A patent/RU2413534C2/ru not_active IP Right Cessation
- 2006-07-13 CN CN2006800254213A patent/CN101222939B/zh not_active Expired - Fee Related
- 2006-07-13 CA CA002615108A patent/CA2615108A1/en not_active Abandoned
- 2006-07-13 EP EP06781064A patent/EP1905453B1/en not_active Not-in-force
- 2006-07-13 ES ES06781064T patent/ES2393675T3/es active Active
- 2006-07-13 US US11/988,613 patent/US20080269353A1/en not_active Abandoned
- 2006-07-13 PL PL06781064T patent/PL1905453T3/pl unknown
- 2006-07-13 KR KR1020077029711A patent/KR101354892B1/ko not_active IP Right Cessation
- 2006-07-13 PT PT67810648T patent/PT1905453E/pt unknown
-
2008
- 2008-02-08 NO NO20080725A patent/NO339109B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101222939A (zh) | 2008-07-16 |
| EP1905453A1 (en) | 2008-04-02 |
| ES2393675T3 (es) | 2012-12-27 |
| RU2008105323A (ru) | 2009-08-20 |
| PL1905453T3 (pl) | 2013-02-28 |
| WO2007007832A1 (ja) | 2007-01-18 |
| KR101354892B1 (ko) | 2014-01-22 |
| EP1905453A4 (en) | 2010-11-17 |
| CA2615108A1 (en) | 2007-01-18 |
| EP1905453B1 (en) | 2012-10-31 |
| KR20080039342A (ko) | 2008-05-07 |
| NO339109B1 (no) | 2016-11-14 |
| RU2413534C2 (ru) | 2011-03-10 |
| PT1905453E (pt) | 2012-12-04 |
| DK1905453T3 (da) | 2012-11-26 |
| US20080269353A1 (en) | 2008-10-30 |
| CN101222939B (zh) | 2010-11-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |