ATE505182T1 - Stabilisierte und konservierte ketotifen enthaltende ophthalmologische zusammensetzungen - Google Patents

Stabilisierte und konservierte ketotifen enthaltende ophthalmologische zusammensetzungen

Info

Publication number
ATE505182T1
ATE505182T1 AT06802303T AT06802303T ATE505182T1 AT E505182 T1 ATE505182 T1 AT E505182T1 AT 06802303 T AT06802303 T AT 06802303T AT 06802303 T AT06802303 T AT 06802303T AT E505182 T1 ATE505182 T1 AT E505182T1
Authority
AT
Austria
Prior art keywords
ketotifene
preserved
stabilized
compositions containing
ophthalmological compositions
Prior art date
Application number
AT06802303T
Other languages
English (en)
Inventor
Fu-Pao Tsao
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE505182T1 publication Critical patent/ATE505182T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT06802303T 2005-08-26 2006-08-24 Stabilisierte und konservierte ketotifen enthaltende ophthalmologische zusammensetzungen ATE505182T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/212,957 US20070048388A1 (en) 2005-08-26 2005-08-26 Stabilized and preserved ketotifen ophthalmic compositions
PCT/US2006/033163 WO2007025094A2 (en) 2005-08-26 2006-08-24 Stabilized and preserved ketotifen ophthalmic compositions

Publications (1)

Publication Number Publication Date
ATE505182T1 true ATE505182T1 (de) 2011-04-15

Family

ID=37670685

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06802303T ATE505182T1 (de) 2005-08-26 2006-08-24 Stabilisierte und konservierte ketotifen enthaltende ophthalmologische zusammensetzungen

Country Status (19)

Country Link
US (4) US20070048388A1 (de)
EP (1) EP1926472B1 (de)
JP (1) JP5172678B2 (de)
KR (1) KR20080042143A (de)
CN (1) CN101252908B (de)
AT (1) ATE505182T1 (de)
AU (2) AU2006282980A1 (de)
BR (1) BRPI0615384B8 (de)
CA (1) CA2619834C (de)
CY (1) CY1111678T1 (de)
DE (1) DE602006021321D1 (de)
DK (1) DK1926472T3 (de)
ES (1) ES2363988T3 (de)
MX (1) MX2008002653A (de)
PL (1) PL1926472T3 (de)
PT (1) PT1926472E (de)
RU (1) RU2442583C2 (de)
SI (1) SI1926472T1 (de)
WO (1) WO2007025094A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070208058A1 (en) * 2004-10-25 2007-09-06 Bryant Roy W Stable Pharmaceutical Compositions and Methods of Making and Using Same
US20070048389A1 (en) * 2005-08-26 2007-03-01 Fu-Pao Tsao Stabilized and preserved ketotifen ophthalmic compositions
US20090220618A1 (en) * 2008-02-29 2009-09-03 Erning Xia Pharmaceutical formulations comprising polyanionic materials and source of hydrogen peroxide
CA2754996A1 (en) * 2009-03-17 2010-09-23 Aciex Therapeutics, Inc. Ophthalmic formulations of ketotifen and methods of use
CN110024781A (zh) * 2019-05-23 2019-07-19 昆明野水生物科技有限公司 一种在常温下能迅速杀灭芽孢的制剂及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4614646A (en) * 1984-12-24 1986-09-30 The Dow Chemical Company Stabilization of peroxide systems in the presence of alkaline earth metal ions
US4819617A (en) * 1986-09-04 1989-04-11 University Of Florida Viscoelastic material for ophthalmic surgery
US5607698A (en) * 1988-08-04 1997-03-04 Ciba-Geigy Corporation Method of preserving ophthalmic solution and compositions therefor
DE68927030T2 (de) * 1988-08-04 1997-02-27 Ciba Geigy Ag Verfahren zur Konservierung ophthalmischer Lösungen und Zusammensetzungen dafür
US5019591A (en) * 1989-02-17 1991-05-28 Pennsylvania Research Corporation Method for treating retinopathy and other small vessel disorders associated with diabetes
EP0938896A1 (de) * 1998-01-15 1999-09-01 Novartis AG In Autoklaven behandelbare pharmazeutische Zusammensetzungen mit Komplexbildner
ATE289804T1 (de) * 1998-10-08 2005-03-15 Hampar L Karagoezian Synergistische antimikrobielle. dermatologische und ophtahalmologische zubereitungen, die ein chlorit und wasserstoffperoxid enthalten
DE60104872T2 (de) * 2000-09-28 2005-09-01 Novartis Ag Stabilisierte ophthalmische wasserstoffperoxidlösung
AR038299A1 (es) * 2002-01-18 2005-01-12 Novartis Ag Metodos para conservar soluciones oftalmicas y soluciones oftalmicas conservadas.
JP2004143157A (ja) * 2002-10-01 2004-05-20 Taisho Pharmaceut Co Ltd 点眼剤
US20050244509A1 (en) * 2004-03-17 2005-11-03 Fu-Pao Tsao Ophthalmic solutions

Also Published As

Publication number Publication date
US20120095050A1 (en) 2012-04-19
SI1926472T1 (sl) 2011-07-29
CA2619834C (en) 2014-05-06
KR20080042143A (ko) 2008-05-14
RU2008111067A (ru) 2009-10-10
CA2619834A1 (en) 2007-03-01
ES2363988T3 (es) 2011-08-22
CN101252908B (zh) 2011-09-14
BRPI0615384B8 (pt) 2021-05-25
WO2007025094A2 (en) 2007-03-01
CN101252908A (zh) 2008-08-27
DK1926472T3 (da) 2011-07-18
DE602006021321D1 (de) 2011-05-26
MX2008002653A (es) 2008-03-18
RU2442583C2 (ru) 2012-02-20
EP1926472A2 (de) 2008-06-04
PL1926472T3 (pl) 2011-09-30
US20070048388A1 (en) 2007-03-01
AU2006282980A1 (en) 2007-03-01
CY1111678T1 (el) 2015-10-07
AU2010241211A1 (en) 2010-11-25
BRPI0615384A2 (pt) 2011-05-17
PT1926472E (pt) 2011-07-11
BRPI0615384B1 (pt) 2019-06-18
US20080193558A1 (en) 2008-08-14
US20130102634A1 (en) 2013-04-25
AU2010241211B2 (en) 2012-12-20
JP5172678B2 (ja) 2013-03-27
WO2007025094A3 (en) 2007-05-18
JP2009506065A (ja) 2009-02-12
EP1926472B1 (de) 2011-04-13

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