NO20076283L - Fremgangsmate for produksjon av lavmolekylaer vektheparin - Google Patents

Fremgangsmate for produksjon av lavmolekylaer vektheparin

Info

Publication number
NO20076283L
NO20076283L NO20076283A NO20076283A NO20076283L NO 20076283 L NO20076283 L NO 20076283L NO 20076283 A NO20076283 A NO 20076283A NO 20076283 A NO20076283 A NO 20076283A NO 20076283 L NO20076283 L NO 20076283L
Authority
NO
Norway
Prior art keywords
molecular weight
heparin
low molecular
production
weight heparin
Prior art date
Application number
NO20076283A
Other languages
English (en)
Inventor
Ragnar Flengsrud
Ole Rasmus Odegaard
Original Assignee
Uni For Miljo Og Biovitenskap
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uni For Miljo Og Biovitenskap filed Critical Uni For Miljo Og Biovitenskap
Publication of NO20076283L publication Critical patent/NO20076283L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/28—Substances of animal origin, e.g. gelatin or collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Oppfinnelsen vedrører en fremgangsmåte for fremstilling av en heparinblanding med meget lav molekylvekt (VLMWH) som har et VLMWH-innhold i forhold til totalt heparininnhold på minst 10 vekt-% idet nevnte fremgangsmåte omfatter kromatografisk eller kjemisk eller ved filtrering reduksjon av den relative andel av heparin med en molekylvekt over 8000Da i en heparinblanding ekstrahert fra et vaskulærisert marint ikke-pattedyr.
NO20076283A 2005-05-09 2007-12-06 Fremgangsmate for produksjon av lavmolekylaer vektheparin NO20076283L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0509433.9A GB0509433D0 (en) 2005-05-09 2005-05-09 Method
PCT/GB2006/001690 WO2006120425A1 (en) 2005-05-09 2006-05-09 Process for the production of a low molecular weight heparin

Publications (1)

Publication Number Publication Date
NO20076283L true NO20076283L (no) 2008-02-06

Family

ID=34685309

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076283A NO20076283L (no) 2005-05-09 2007-12-06 Fremgangsmate for produksjon av lavmolekylaer vektheparin

Country Status (10)

Country Link
US (1) US20090105194A1 (no)
EP (1) EP1899384A1 (no)
JP (1) JP2008543987A (no)
CN (1) CN101218259B (no)
AU (1) AU2006245577A1 (no)
CA (1) CA2608136A1 (no)
GB (1) GB0509433D0 (no)
NO (1) NO20076283L (no)
NZ (1) NZ563821A (no)
WO (1) WO2006120425A1 (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101370536A (zh) 2005-12-13 2009-02-18 埃克塞拉有限责任公司 用于从血液中体外去除病原微生物、炎性细胞或炎性蛋白质的方法
WO2008155683A1 (en) 2007-06-18 2008-12-24 Firmenich Sa Malodor counteracting compositions and method for their use
EP2167165B1 (en) * 2007-06-18 2014-09-24 ExThera Medical Corporation Full length heparin for restoration of the condition of blood
GB0812919D0 (en) * 2008-07-15 2008-08-20 Norwegian University Of Life Sciences Process
JP5925693B2 (ja) 2009-12-01 2016-05-25 エクステラ・メディカル・コーポレーション 表面固定した多糖類を用いた、血液からのサイトカイン除去法
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
EP2861273B1 (en) 2012-06-13 2017-08-23 ExThera Medical Corporation Use of heparin and carbohydrates to treat cancer
CN110772677A (zh) 2013-06-24 2020-02-11 艾克塞拉医疗公司 含有涂覆甘露糖的基质的血液过滤系统
CN105705177B (zh) 2013-11-08 2019-10-22 艾克塞拉医疗公司 使用吸附介质诊断感染性疾病的方法
EP3134146A4 (en) 2014-04-24 2018-01-10 ExThera Medical Corporation Method for removing bacteria from blood using high flow rate
WO2016048901A1 (en) 2014-09-22 2016-03-31 Exthera Medical Corporation Wearable hemoperfusion device
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
EP3422943A4 (en) 2016-03-02 2019-10-16 ExThera Medical Corporation METHOD OF TREATING DRUG ENTRIES
CN108179162A (zh) * 2018-01-16 2018-06-19 浙江海洋大学 一种低分子量肝素的制备方法
WO2020013346A1 (en) 2018-07-11 2020-01-16 Ajinomoto Co., Inc. Method for enzymatic sulfurylation of alcohols and amines using bacterium of the family enterobacteriaceae
EP3943513A4 (en) 2019-04-26 2022-12-21 Laboratorios Farmacéuticos Rovi, S.A. METHOD FOR OBTAINING LOW MOLECULAR WEIGHT HEPARIN BY TANGENTIAL FLOW FILTRATION
KR20220009400A (ko) 2019-05-16 2022-01-24 엑스테라 메디컬 코퍼레이션 내피 글리코칼릭스 구조의 조절 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4533549A (en) * 1983-01-04 1985-08-06 Lasker Sigmund E Antithrombotic agent
US4788307A (en) * 1986-04-30 1988-11-29 Choay S.A. Oligosaccharidic fractions devoid or practically devoid of antithrombotic activity
IT1230582B (it) * 1988-10-21 1991-10-28 Opocrin S P A Lab Farmabiologi Oliogosaccaridi di dermatan solfato ed eparina aventi attivita' antiaterosclerotica
FR2663639B1 (fr) * 1990-06-26 1994-03-18 Rhone Poulenc Sante Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation.
US5767269A (en) * 1996-10-01 1998-06-16 Hamilton Civic Hospitals Research Development Inc. Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics
CN1284510A (zh) * 1999-08-17 2001-02-21 孙润伟 利用猪、牛、羊肺沉淀法生产肝素钠
US7618652B2 (en) * 2001-03-23 2009-11-17 Hepmarin As Glycosaminoglycan anticoagulants derived from fish
EP1524276A1 (en) * 2003-10-16 2005-04-20 Laboratori Derivati Organici S.P.A. Multistep process for the physical depolymerization of heparin and products obtained therefrom

Also Published As

Publication number Publication date
CN101218259A (zh) 2008-07-09
JP2008543987A (ja) 2008-12-04
CA2608136A1 (en) 2006-11-16
WO2006120425A1 (en) 2006-11-16
NZ563821A (en) 2010-09-30
AU2006245577A1 (en) 2006-11-16
GB0509433D0 (en) 2005-06-15
CN101218259B (zh) 2011-06-15
EP1899384A1 (en) 2008-03-19
US20090105194A1 (en) 2009-04-23

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