NO20075911L - Genetisk modifisert mikroorganisme og fremgangsmate for fremstilling av makrolidforbindelser ved anvendelse av mikroorganismen - Google Patents
Genetisk modifisert mikroorganisme og fremgangsmate for fremstilling av makrolidforbindelser ved anvendelse av mikroorganismenInfo
- Publication number
- NO20075911L NO20075911L NO20075911A NO20075911A NO20075911L NO 20075911 L NO20075911 L NO 20075911L NO 20075911 A NO20075911 A NO 20075911A NO 20075911 A NO20075911 A NO 20075911A NO 20075911 L NO20075911 L NO 20075911L
- Authority
- NO
- Norway
- Prior art keywords
- microorganism
- genetically modified
- macrolide compound
- modified microorganism
- macrolide compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 239000003120 macrolide antibiotic agent Substances 0.000 title abstract 6
- 244000005700 microbiome Species 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 239000001963 growth medium Substances 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
- C12P17/162—Heterorings having oxygen atoms as the only ring heteroatoms, e.g. Lasalocid
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005154114 | 2005-05-26 | ||
| PCT/JP2006/310835 WO2006126723A1 (ja) | 2005-05-26 | 2006-05-24 | 遺伝子組換え微生物およびそれらの微生物を用いるマクロライド系化合物の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20075911L true NO20075911L (no) | 2008-02-26 |
Family
ID=37452135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20075911A NO20075911L (no) | 2005-05-26 | 2007-11-15 | Genetisk modifisert mikroorganisme og fremgangsmate for fremstilling av makrolidforbindelser ved anvendelse av mikroorganismen |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20090215134A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1911843B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPWO2006126723A1 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20080012845A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101184838B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2006250304B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0610145A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2608841A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL187081A0 (cg-RX-API-DMAC7.html) |
| NO (1) | NO20075911L (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ562921A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2394906C2 (cg-RX-API-DMAC7.html) |
| SG (1) | SG148168A1 (cg-RX-API-DMAC7.html) |
| TW (1) | TW200716744A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006126723A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005265443B2 (en) * | 2004-07-20 | 2008-09-04 | Eisai R & D Management Co., Ltd | DNA coding for polypeptide participating in biosynthesis of pladienolide |
| CN102010403A (zh) | 2005-10-13 | 2011-04-13 | 卫材R&D管理有限公司 | 普拉二烯内酯b和普拉二烯内酯d的全合成 |
| CN101730693A (zh) | 2007-07-06 | 2010-06-09 | 卫材R&D管理有限公司 | 大环内酯系化合物的制造方法及其制造中间体 |
| JP5524053B2 (ja) * | 2008-06-04 | 2014-06-18 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ハーボキシジエンの生合成に関与するポリペプチドをコードするｄｎａ |
| CN107074827B (zh) * | 2014-05-15 | 2020-12-18 | 卫材研究发展管理有限公司 | 普拉二烯内酯吡啶化合物和使用方法 |
| SG11201803519YA (en) | 2015-11-18 | 2018-06-28 | Eisai R&D Man Co Ltd | A solid state form of pladienolide pyridine compounds and methods of use |
| CN110408643B (zh) * | 2018-11-30 | 2023-08-22 | 云南大学 | 一种提高自溶链霉菌洋橄榄叶素及其衍生物产量的方法 |
| CN115247179B (zh) * | 2021-04-25 | 2024-03-12 | 上海健康医学院 | 一种聚酮化合物骨架及其后修饰物的生物合成基因簇及其应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824513A (en) * | 1991-01-17 | 1998-10-20 | Abbott Laboratories | Recombinant DNA method for producing erythromycin analogs |
| JP2002526114A (ja) * | 1998-10-02 | 2002-08-20 | コーサン バイオサイエンシーズ， インコーポレイテッド | ポリケチドシンターゼおよびその組換えｄｎａ構築物 |
| TWI312681B (en) * | 2001-02-01 | 2009-08-01 | Novel physiologically active substance | |
| RU2372404C2 (ru) * | 2001-10-19 | 2009-11-10 | Сумитомо Кемикал Компани, Лимитед | Метаболизирующий гербицид белок, его ген и их применение |
| EP1500704B1 (en) * | 2002-04-12 | 2009-03-25 | Mercian Corporation | Expression system of actinomycete-origin cytochrome p-450 in escherichia coli |
| TWI334866B (en) * | 2002-05-29 | 2010-12-21 | Mercian Corp | Novel physiologically active substances |
| US7256178B2 (en) * | 2002-07-31 | 2007-08-14 | Eisai Co., Ltd. | Physiologically active substances |
| EP1541570A4 (en) * | 2002-07-31 | 2008-05-21 | Mercian Corp | NEW PHYSIOLOGICALLY EFFECTIVE SUBSTANCE |
| RU2330069C2 (ru) * | 2002-11-29 | 2008-07-27 | Мершан Корпорейшн | Способ получения макролидного соединения и штаммы streptomyces sp., mortierella sp. и micromonosporaceae |
| CA2453080C (en) * | 2003-01-21 | 2006-02-21 | Ecopia Biosciences Inc. | Polyene polyketides, processes for their production and their use as a pharmaceutical |
| US7932083B2 (en) * | 2003-11-27 | 2011-04-26 | Mercian Corporation | DNA participating in hydroxylation of macrolide compound |
| AU2005265443B2 (en) * | 2004-07-20 | 2008-09-04 | Eisai R & D Management Co., Ltd | DNA coding for polypeptide participating in biosynthesis of pladienolide |
| RU2327486C1 (ru) * | 2007-07-04 | 2008-06-27 | Валентина Васильевна Малиновская | Лекарственное средство для лечения инфекционно-воспалительных заболеваний, обладающее иммуномодулирующим, антивирусным, антибактериальным, антиоксидантным, мембраностабилизирующим, противовоспалительным, антитоксическим свойствами |
-
2006
- 2006-05-23 TW TW095118236A patent/TW200716744A/zh unknown
- 2006-05-24 CN CN2006800182893A patent/CN101184838B/zh not_active Expired - Fee Related
- 2006-05-24 NZ NZ562921A patent/NZ562921A/en not_active IP Right Cessation
- 2006-05-24 EP EP06756783A patent/EP1911843B1/en active Active
- 2006-05-24 AU AU2006250304A patent/AU2006250304B2/en not_active Ceased
- 2006-05-24 CA CA002608841A patent/CA2608841A1/en not_active Abandoned
- 2006-05-24 JP JP2007517936A patent/JPWO2006126723A1/ja active Pending
- 2006-05-24 WO PCT/JP2006/310835 patent/WO2006126723A1/ja not_active Ceased
- 2006-05-24 RU RU2007148928/13A patent/RU2394906C2/ru not_active IP Right Cessation
- 2006-05-24 US US11/919,579 patent/US20090215134A1/en not_active Abandoned
- 2006-05-24 SG SG200808288-5A patent/SG148168A1/en unknown
- 2006-05-24 KR KR1020077024481A patent/KR20080012845A/ko not_active Ceased
- 2006-05-24 BR BRPI0610145-3A patent/BRPI0610145A2/pt not_active IP Right Cessation
-
2007
- 2007-11-01 IL IL187081A patent/IL187081A0/en unknown
- 2007-11-15 NO NO20075911A patent/NO20075911L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0610145A2 (pt) | 2010-06-01 |
| WO2006126723A1 (ja) | 2006-11-30 |
| CA2608841A1 (en) | 2006-11-30 |
| JPWO2006126723A1 (ja) | 2008-12-25 |
| CN101184838B (zh) | 2011-06-15 |
| SG148168A1 (en) | 2008-12-31 |
| IL187081A0 (cg-RX-API-DMAC7.html) | 2008-02-09 |
| KR20080012845A (ko) | 2008-02-12 |
| RU2394906C2 (ru) | 2010-07-20 |
| TW200716744A (en) | 2007-05-01 |
| AU2006250304B2 (en) | 2010-12-09 |
| EP1911843B1 (en) | 2012-03-14 |
| RU2007148928A (ru) | 2009-07-10 |
| NZ562921A (en) | 2009-06-26 |
| US20090215134A1 (en) | 2009-08-27 |
| EP1911843A4 (en) | 2009-01-07 |
| AU2006250304A1 (en) | 2006-11-30 |
| EP1911843A1 (en) | 2008-04-16 |
| CN101184838A (zh) | 2008-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |