NO20075022L - (7-(2-(4-(3-trifluormetylfenyl)-1,2,3,6-tetrahydropyrid-1-yl)etyl) isokinolinbesylatsalt, fremstilling og terapeutiske anvendelser derav - Google Patents
(7-(2-(4-(3-trifluormetylfenyl)-1,2,3,6-tetrahydropyrid-1-yl)etyl) isokinolinbesylatsalt, fremstilling og terapeutiske anvendelser deravInfo
- Publication number
- NO20075022L NO20075022L NO20075022A NO20075022A NO20075022L NO 20075022 L NO20075022 L NO 20075022L NO 20075022 A NO20075022 A NO 20075022A NO 20075022 A NO20075022 A NO 20075022A NO 20075022 L NO20075022 L NO 20075022L
- Authority
- NO
- Norway
- Prior art keywords
- ethyl
- tetrahydropyrid
- trifluoromethylphenyl
- preparation
- besylate salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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-
- A—HUMAN NECESSITIES
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A61P25/00—Drugs for disorders of the nervous system
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P31/04—Antibacterial agents
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- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
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- A—HUMAN NECESSITIES
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- A61P31/14—Antivirals for RNA viruses
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- A61P31/20—Antivirals for DNA viruses
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Transplantation (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0502611A FR2883285B1 (fr) | 2005-03-17 | 2005-03-17 | Sel besylate de la 7-(2-(4-(3-trifluoromethyl-phenyl) -1,2,3,6-tetrahudro-pyrid-1-yl)ethyl) isoquinoleine, sa preparation et son utilisation en therapeutique |
PCT/FR2006/000566 WO2006097624A1 (fr) | 2005-03-17 | 2006-03-15 | Sel besylate de la 7-(2-(4-(3-trifluoromethyl-phenyl)-1,2,3,6-tetrahydro-pyrid-1-yl)ethyl) isoquinoleine, sa preparation et son utilisation en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20075022L true NO20075022L (no) | 2007-10-04 |
Family
ID=35285429
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20075022A NO20075022L (no) | 2005-03-17 | 2007-10-04 | (7-(2-(4-(3-trifluormetylfenyl)-1,2,3,6-tetrahydropyrid-1-yl)etyl) isokinolinbesylatsalt, fremstilling og terapeutiske anvendelser derav |
Country Status (34)
Country | Link |
---|---|
US (1) | US7795277B2 (hr) |
EP (1) | EP1861389B1 (hr) |
JP (1) | JP2008534450A (hr) |
KR (1) | KR20070115258A (hr) |
CN (1) | CN101137644A (hr) |
AR (1) | AR053448A1 (hr) |
AT (1) | ATE399161T1 (hr) |
AU (1) | AU2006224465B2 (hr) |
BR (1) | BRPI0607614A2 (hr) |
CA (1) | CA2599637A1 (hr) |
CR (1) | CR9352A (hr) |
CY (1) | CY1108366T1 (hr) |
DE (1) | DE602006001590D1 (hr) |
DK (1) | DK1861389T3 (hr) |
EA (1) | EA011560B1 (hr) |
ES (1) | ES2309957T3 (hr) |
FR (1) | FR2883285B1 (hr) |
HR (1) | HRP20080447T3 (hr) |
IL (1) | IL185537A (hr) |
MA (1) | MA29348B1 (hr) |
MX (1) | MX2007011021A (hr) |
MY (1) | MY138296A (hr) |
NO (1) | NO20075022L (hr) |
NZ (1) | NZ561027A (hr) |
PL (1) | PL1861389T3 (hr) |
PT (1) | PT1861389E (hr) |
RS (1) | RS50611B (hr) |
SI (1) | SI1861389T1 (hr) |
TN (1) | TNSN07317A1 (hr) |
TW (1) | TW200700410A (hr) |
UA (1) | UA90304C2 (hr) |
UY (1) | UY29425A1 (hr) |
WO (1) | WO2006097624A1 (hr) |
ZA (1) | ZA200707488B (hr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
EP2089383B1 (en) | 2006-11-09 | 2015-09-16 | Probiodrug AG | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
US9126987B2 (en) | 2006-11-30 | 2015-09-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
JP5930573B2 (ja) | 2007-03-01 | 2016-06-15 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤の新規使用 |
WO2008128985A1 (en) | 2007-04-18 | 2008-10-30 | Probiodrug Ag | Thiourea derivatives as glutaminyl cyclase inhibitors |
ES2548913T3 (es) | 2009-09-11 | 2015-10-21 | Probiodrug Ag | Derivados heterocíclicos como inhibidores de glutaminil ciclasa |
EP2542549B1 (en) | 2010-03-03 | 2016-05-11 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
EA022420B1 (ru) | 2010-03-10 | 2015-12-30 | Пробиодруг Аг | Гетероциклические ингибиторы глутаминилциклазы (qc, ec 2.3.2.5) |
US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
US8530670B2 (en) | 2011-03-16 | 2013-09-10 | Probiodrug Ag | Inhibitors |
EP3461819B1 (en) | 2017-09-29 | 2020-05-27 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2736053B1 (fr) * | 1995-06-28 | 1997-09-19 | Sanofi Sa | Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines |
EE05055B1 (et) * | 1999-10-22 | 2008-08-15 | Sanofi-Synthlabo | TNF-i aktiivsust prssivad fenl- ja pridltetrahdropridiinid |
WO2002085888A1 (fr) * | 2001-04-20 | 2002-10-31 | Sanofi-Synthelabo | Tetrahydropyridyl-alkyl-heterocycles, procede pour leur preparation et compositions pharmaceutiques les contenants |
FR2823749B1 (fr) * | 2001-04-20 | 2004-02-20 | Sanofi Synthelabo | Phenyl- et pyridyl-piperidines, procede pour leur preparation et compositions pharmaceutiques les contenant |
-
2005
- 2005-03-17 FR FR0502611A patent/FR2883285B1/fr not_active Expired - Fee Related
-
2006
- 2006-03-14 MY MYPI20061092A patent/MY138296A/en unknown
- 2006-03-15 EP EP06726092A patent/EP1861389B1/fr active Active
- 2006-03-15 DE DE602006001590T patent/DE602006001590D1/de active Active
- 2006-03-15 PL PL06726092T patent/PL1861389T3/pl unknown
- 2006-03-15 RS RSP-2008/0423A patent/RS50611B/sr unknown
- 2006-03-15 CA CA002599637A patent/CA2599637A1/fr not_active Abandoned
- 2006-03-15 AU AU2006224465A patent/AU2006224465B2/en not_active Ceased
- 2006-03-15 ES ES06726092T patent/ES2309957T3/es active Active
- 2006-03-15 NZ NZ561027A patent/NZ561027A/en not_active IP Right Cessation
- 2006-03-15 CN CNA2006800080866A patent/CN101137644A/zh active Pending
- 2006-03-15 WO PCT/FR2006/000566 patent/WO2006097624A1/fr active Application Filing
- 2006-03-15 UA UAA200711489A patent/UA90304C2/ru unknown
- 2006-03-15 DK DK06726092T patent/DK1861389T3/da active
- 2006-03-15 AT AT06726092T patent/ATE399161T1/de active
- 2006-03-15 EA EA200702004A patent/EA011560B1/ru not_active IP Right Cessation
- 2006-03-15 PT PT06726092T patent/PT1861389E/pt unknown
- 2006-03-15 ZA ZA200707488A patent/ZA200707488B/xx unknown
- 2006-03-15 BR BRPI0607614-9A patent/BRPI0607614A2/pt not_active IP Right Cessation
- 2006-03-15 KR KR1020077021155A patent/KR20070115258A/ko not_active Application Discontinuation
- 2006-03-15 SI SI200630065T patent/SI1861389T1/sl unknown
- 2006-03-15 MX MX2007011021A patent/MX2007011021A/es active IP Right Grant
- 2006-03-15 JP JP2008501367A patent/JP2008534450A/ja not_active Ceased
- 2006-03-16 AR ARP060101027A patent/AR053448A1/es unknown
- 2006-03-16 TW TW095108870A patent/TW200700410A/zh unknown
- 2006-03-17 UY UY29425A patent/UY29425A1/es unknown
-
2007
- 2007-08-17 TN TNP2007000317A patent/TNSN07317A1/en unknown
- 2007-08-27 IL IL185537A patent/IL185537A/en not_active IP Right Cessation
- 2007-08-28 CR CR9352A patent/CR9352A/es not_active Application Discontinuation
- 2007-09-12 US US11/853,920 patent/US7795277B2/en not_active Expired - Fee Related
- 2007-09-26 MA MA30248A patent/MA29348B1/fr unknown
- 2007-10-04 NO NO20075022A patent/NO20075022L/no not_active Application Discontinuation
-
2008
- 2008-09-15 HR HR20080447T patent/HRP20080447T3/hr unknown
- 2008-09-24 CY CY20081101039T patent/CY1108366T1/el unknown
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