UY29425A1 - Sal besilato de 7-(2- (4-(3- trifluorometil-fenil)-1,2,3,6-tetrahidro-pirid-1-il)etil) isoquinoleina, su preparacion y su utilización en terapéutica.- - Google Patents

Sal besilato de 7-(2- (4-(3- trifluorometil-fenil)-1,2,3,6-tetrahidro-pirid-1-il)etil) isoquinoleina, su preparacion y su utilización en terapéutica.-

Info

Publication number
UY29425A1
UY29425A1 UY29425A UY29425A UY29425A1 UY 29425 A1 UY29425 A1 UY 29425A1 UY 29425 A UY29425 A UY 29425A UY 29425 A UY29425 A UY 29425A UY 29425 A1 UY29425 A1 UY 29425A1
Authority
UY
Uruguay
Prior art keywords
preparation
isoquinoleina
pirid
trifluorometil
tetrahidro
Prior art date
Application number
UY29425A
Other languages
English (en)
Inventor
Barre Corinne
Monnier Oliver
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY29425A1 publication Critical patent/UY29425A1/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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    • A—HUMAN NECESSITIES
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
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    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
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    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
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Abstract

L invención se refiere a la sal besilato de 7-(2-(4-(3-trifluorometil-fenil)-1,2,3,6-tetrahidro-pirid-1il)etil) isoquinoleína. La invención se refiere igualmente a un procedimiento de preparación de besilato de 7-(2-(4-(3-trifluorometil-fenil)-1,2,3,6-tetrahidro-pirid-1-il) isoquinoleína, así como a su utilización en terapéutica.
UY29425A 2005-03-17 2006-03-17 Sal besilato de 7-(2- (4-(3- trifluorometil-fenil)-1,2,3,6-tetrahidro-pirid-1-il)etil) isoquinoleina, su preparacion y su utilización en terapéutica.- UY29425A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0502611A FR2883285B1 (fr) 2005-03-17 2005-03-17 Sel besylate de la 7-(2-(4-(3-trifluoromethyl-phenyl) -1,2,3,6-tetrahudro-pyrid-1-yl)ethyl) isoquinoleine, sa preparation et son utilisation en therapeutique

Publications (1)

Publication Number Publication Date
UY29425A1 true UY29425A1 (es) 2006-10-31

Family

ID=35285429

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29425A UY29425A1 (es) 2005-03-17 2006-03-17 Sal besilato de 7-(2- (4-(3- trifluorometil-fenil)-1,2,3,6-tetrahidro-pirid-1-il)etil) isoquinoleina, su preparacion y su utilización en terapéutica.-

Country Status (34)

Country Link
US (1) US7795277B2 (es)
EP (1) EP1861389B1 (es)
JP (1) JP2008534450A (es)
KR (1) KR20070115258A (es)
CN (1) CN101137644A (es)
AR (1) AR053448A1 (es)
AT (1) ATE399161T1 (es)
AU (1) AU2006224465B2 (es)
BR (1) BRPI0607614A2 (es)
CA (1) CA2599637A1 (es)
CR (1) CR9352A (es)
CY (1) CY1108366T1 (es)
DE (1) DE602006001590D1 (es)
DK (1) DK1861389T3 (es)
EA (1) EA011560B1 (es)
ES (1) ES2309957T3 (es)
FR (1) FR2883285B1 (es)
HR (1) HRP20080447T3 (es)
IL (1) IL185537A (es)
MA (1) MA29348B1 (es)
MX (1) MX2007011021A (es)
MY (1) MY138296A (es)
NO (1) NO20075022L (es)
NZ (1) NZ561027A (es)
PL (1) PL1861389T3 (es)
PT (1) PT1861389E (es)
RS (1) RS50611B (es)
SI (1) SI1861389T1 (es)
TN (1) TNSN07317A1 (es)
TW (1) TW200700410A (es)
UA (1) UA90304C2 (es)
UY (1) UY29425A1 (es)
WO (1) WO2006097624A1 (es)
ZA (1) ZA200707488B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7732162B2 (en) 2003-05-05 2010-06-08 Probiodrug Ag Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases
WO2008055945A1 (en) 2006-11-09 2008-05-15 Probiodrug Ag 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases
ATE554085T1 (de) 2006-11-30 2012-05-15 Probiodrug Ag Neue inhibitoren von glutaminylcyclase
EP2117540A1 (en) 2007-03-01 2009-11-18 Probiodrug AG New use of glutaminyl cyclase inhibitors
JP5667440B2 (ja) 2007-04-18 2015-02-12 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体
SG178953A1 (en) 2009-09-11 2012-04-27 Probiodrug Ag Heterocylcic derivatives as inhibitors of glutaminyl cyclase
US9181233B2 (en) 2010-03-03 2015-11-10 Probiodrug Ag Inhibitors of glutaminyl cyclase
AU2011226074B2 (en) 2010-03-10 2015-01-22 Vivoryon Therapeutics N.V. Heterocyclic inhibitors of glutaminyl cyclase (QC, EC 2.3.2.5)
US8541596B2 (en) 2010-04-21 2013-09-24 Probiodrug Ag Inhibitors
ES2570167T3 (es) 2011-03-16 2016-05-17 Probiodrug Ag Derivados de benzimidazol como inhibidores de glutaminil ciclasa
ES2812698T3 (es) 2017-09-29 2021-03-18 Probiodrug Ag Inhibidores de glutaminil ciclasa

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2736053B1 (fr) * 1995-06-28 1997-09-19 Sanofi Sa Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines
CZ301566B6 (cs) * 1999-10-22 2010-04-21 Sanofi-Aventis Deriváty fenyl- a pyridyl-tetrahydropyridinu, zpusob jejich prípravy a farmaceutická kompozice, která je obsahuje
WO2002085888A1 (fr) * 2001-04-20 2002-10-31 Sanofi-Synthelabo Tetrahydropyridyl-alkyl-heterocycles, procede pour leur preparation et compositions pharmaceutiques les contenants
FR2823749B1 (fr) * 2001-04-20 2004-02-20 Sanofi Synthelabo Phenyl- et pyridyl-piperidines, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
WO2006097624A1 (fr) 2006-09-21
CY1108366T1 (el) 2014-02-12
MY138296A (en) 2009-05-29
BRPI0607614A2 (pt) 2009-09-22
CN101137644A (zh) 2008-03-05
EP1861389B1 (fr) 2008-06-25
SI1861389T1 (sl) 2008-10-31
PL1861389T3 (pl) 2008-12-31
FR2883285B1 (fr) 2007-05-18
CR9352A (es) 2008-02-20
AU2006224465B2 (en) 2011-10-13
CA2599637A1 (fr) 2006-09-21
DK1861389T3 (da) 2008-10-20
TNSN07317A1 (en) 2008-12-31
RS50611B (sr) 2010-06-30
KR20070115258A (ko) 2007-12-05
FR2883285A1 (fr) 2006-09-22
EA011560B1 (ru) 2009-04-28
ZA200707488B (en) 2008-12-31
JP2008534450A (ja) 2008-08-28
PT1861389E (pt) 2008-09-11
HRP20080447T3 (en) 2008-10-31
MX2007011021A (es) 2008-03-18
UA90304C2 (en) 2010-04-26
TW200700410A (en) 2007-01-01
IL185537A0 (en) 2008-01-06
ES2309957T3 (es) 2008-12-16
AR053448A1 (es) 2007-05-09
NO20075022L (no) 2007-10-04
NZ561027A (en) 2010-11-26
IL185537A (en) 2011-08-31
ATE399161T1 (de) 2008-07-15
MA29348B1 (fr) 2008-03-03
DE602006001590D1 (de) 2008-08-07
US20080085917A1 (en) 2008-04-10
EA200702004A1 (ru) 2008-02-28
US7795277B2 (en) 2010-09-14
EP1861389A1 (fr) 2007-12-05
AU2006224465A1 (en) 2006-09-21

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