NO20074104L - Fremgangsmater og systemer for diagnose, prognose og seleksjon ved behandling av leukemi - Google Patents
Fremgangsmater og systemer for diagnose, prognose og seleksjon ved behandling av leukemiInfo
- Publication number
- NO20074104L NO20074104L NO20074104A NO20074104A NO20074104L NO 20074104 L NO20074104 L NO 20074104L NO 20074104 A NO20074104 A NO 20074104A NO 20074104 A NO20074104 A NO 20074104A NO 20074104 L NO20074104 L NO 20074104L
- Authority
- NO
- Norway
- Prior art keywords
- leukemia
- treatment
- genes
- prognosis
- diagnosis
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
Foreliggende oppfinnelse tilveiebringer fremgangsmåter, systemer og utstyr for prognose, diagnose og seleksjon av behandling for AML eller andre typer av leukemi. Gener prognostiske for klinisk resultat for leukemipasienter kan identifiseres ifølge foreliggende oppfinnelse. Leukemi sykdomsgener kan også identifiseres ifølge foreliggende oppfinnelse. Disse genene er differensielt uttrykt i PBMC'er fra AML-pasienter relativt til sykdomsfri mennesker. Disse genene kan anvendes for diagnose eller overvåkning av utvikling, progresjon eller behandling av AML.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65311705P | 2005-02-16 | 2005-02-16 | |
PCT/US2006/005855 WO2006089233A2 (en) | 2005-02-16 | 2006-02-16 | Methods and systems for diagnosis, prognosis and selection of treatment of leukemia |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20074104L true NO20074104L (no) | 2007-11-13 |
Family
ID=36659874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20074104A NO20074104L (no) | 2005-02-16 | 2007-08-08 | Fremgangsmater og systemer for diagnose, prognose og seleksjon ved behandling av leukemi |
Country Status (14)
Country | Link |
---|---|
US (1) | US20080280774A1 (no) |
EP (1) | EP1848994A2 (no) |
JP (1) | JP2008529557A (no) |
KR (1) | KR20070106027A (no) |
CN (1) | CN101156067A (no) |
AU (1) | AU2006214034A1 (no) |
BR (1) | BRPI0607753A2 (no) |
CA (1) | CA2598025A1 (no) |
CR (1) | CR9315A (no) |
IL (1) | IL185189A0 (no) |
MX (1) | MX2007009911A (no) |
NO (1) | NO20074104L (no) |
RU (1) | RU2007130722A (no) |
WO (1) | WO2006089233A2 (no) |
Families Citing this family (60)
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EP1888784A2 (en) * | 2005-05-18 | 2008-02-20 | Wyeth a Corporation of the State of Delaware | Leukemia disease genes and uses thereof |
US10460080B2 (en) | 2005-09-08 | 2019-10-29 | Gearbox, Llc | Accessing predictive data |
KR100617467B1 (ko) * | 2005-09-27 | 2006-09-01 | 디지탈 지노믹스(주) | 급성 골수성 백혈병 환자의 항암제 치료 반응성 예측용마커 |
US20090075266A1 (en) * | 2007-09-14 | 2009-03-19 | Predictive Biosciences Corporation | Multiple analyte diagnostic readout |
JP5745273B2 (ja) | 2007-11-30 | 2015-07-08 | クラリエント ダイアグノスティック サービシーズ, インコーポレイテッド | 化学療法のためのマーカーとしてのtle3 |
CN102046660A (zh) | 2008-03-26 | 2011-05-04 | 塞勒兰特治疗公司 | 骨髓性血液学增殖性病症相关的免疫球蛋白和/或toll样受体蛋白及其用途 |
EP2113257A1 (en) | 2008-04-30 | 2009-11-04 | Consorzio per il Centro di Biomedica Moleculare Scrl | Polyelectrolyte with positive net charge for use as medicament and diagnostic for cancer |
US20100041055A1 (en) * | 2008-08-12 | 2010-02-18 | Stokes Bio Limited | Novel gene normalization methods |
US8748103B2 (en) * | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
GB2483810B (en) | 2008-11-07 | 2012-09-05 | Sequenta Inc | Methods for correlating clonotypes with diseases in a population |
US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
US8691510B2 (en) * | 2008-11-07 | 2014-04-08 | Sequenta, Inc. | Sequence analysis of complex amplicons |
PT2387627E (pt) | 2009-01-15 | 2016-06-03 | Adaptive Biotechnologies Corp | Determinação do perfil de imunidade adaptativa e métodos de geração de anticorpos monoclonais |
KR100937720B1 (ko) * | 2009-04-20 | 2010-01-20 | 전남대학교산학협력단 | CFH 또는 ApoH를 급성골수성백혈병 관해 진단용 생화학적 마커로 사용하는 방법 |
WO2010151416A1 (en) | 2009-06-25 | 2010-12-29 | Fred Hutchinson Cancer Research Center | Method of measuring adaptive immunity |
US8692681B2 (en) * | 2009-07-07 | 2014-04-08 | Koninklijke Philips N.V. | Dynamic PET imaging with isotope contamination compensation |
GB2472856B (en) | 2009-08-21 | 2012-07-11 | Cantargia Ab | IL1-RAP modulators and uses thereof |
JP5503942B2 (ja) * | 2009-10-30 | 2014-05-28 | シスメックス株式会社 | 疾患の罹患の判定方法 |
US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
JP5467267B2 (ja) * | 2010-03-05 | 2014-04-09 | 国立大学法人大阪大学 | 機器制御装置、機器システム、機器制御方法、機器制御プログラム、および記録媒体 |
DK2665749T3 (en) | 2011-01-19 | 2016-03-21 | Cantargia Ab | Anti-il1rap antibodies and their use for the treatment of solid tumors |
US9012422B2 (en) | 2011-08-10 | 2015-04-21 | Wake Forest University Health Sciences | Method of treating acute myelogenous leukemia |
US9873918B2 (en) | 2011-08-11 | 2018-01-23 | Albert Einstein College Of Medicine, Inc. | Treatment of acute myeloid leukemia and myelodysplastic syndromes |
US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
AU2012325791B2 (en) | 2011-10-21 | 2018-04-05 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
EP2788509B1 (en) | 2011-12-09 | 2018-07-11 | Adaptive Biotechnologies Corporation | Diagnosis of lymphoid malignancies and minimal residual disease detection |
US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
JP6156621B2 (ja) * | 2012-02-14 | 2017-07-05 | 国立大学法人 岡山大学 | Atllの診断のためのデータ取得方法、atll診断用キットおよびatll診断システム |
EP3372694A1 (en) | 2012-03-05 | 2018-09-12 | Adaptive Biotechnologies Corporation | Determining paired immune receptor chains from frequency matched subunits |
SG10201507700VA (en) | 2012-05-08 | 2015-10-29 | Adaptive Biotechnologies Corp | Compositions and method for measuring and calibrating amplification bias in multiplexed pcr reactions |
IN2014DN10075A (no) * | 2012-05-31 | 2015-08-21 | Univ Kinki | |
CN105189779B (zh) | 2012-10-01 | 2018-05-11 | 适应生物技术公司 | 通过适应性免疫受体多样性和克隆性表征进行的免疫能力评估 |
WO2015160439A2 (en) | 2014-04-17 | 2015-10-22 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
EP3114240B1 (en) | 2014-03-05 | 2019-07-24 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
WO2016069886A1 (en) | 2014-10-29 | 2016-05-06 | Adaptive Biotechnologies Corporation | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
EP3498866A1 (en) | 2014-11-25 | 2019-06-19 | Adaptive Biotechnologies Corp. | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
AU2016222788B2 (en) | 2015-02-24 | 2022-03-31 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing |
AU2016242967B2 (en) | 2015-04-01 | 2021-07-01 | Adaptive Biotechnologies Corp. | Method of identifying human compatible T cell receptors specific for an antigenic target |
US11474106B2 (en) | 2015-07-08 | 2022-10-18 | Lawrence Livermore National Security, Llc | Methods for cytotoxic chemotherapy-based predictive assays |
WO2017180489A1 (en) | 2016-04-12 | 2017-10-19 | The Johns Hopkins University | Quantitative determination of nucleoside analogue drugs in genomic dna or rna |
US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
WO2018132766A1 (en) * | 2017-01-12 | 2018-07-19 | The Regents Of The University Of California | Cytotoxic chemotherapy-based predictive assays for acute myeloid leukemia |
CN106841624B (zh) * | 2017-01-26 | 2019-02-22 | 庄磊靓 | 抗人cd4和抗人cd184单克隆抗体作为标志物的应用 |
US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
CN108182347B (zh) * | 2018-01-17 | 2022-02-22 | 广东工业大学 | 一种大规模跨平台基因表达数据分类方法 |
KR102327062B1 (ko) | 2018-03-20 | 2021-11-17 | 딜로이트컨설팅유한회사 | 임상시험 결과 예측 장치 및 방법 |
CN109187987B (zh) * | 2018-08-23 | 2021-05-11 | 中国人民解放军第三0九医院 | Ms4a3蛋白作为标志物在诊断活动性结核病中的应用 |
US11497795B2 (en) | 2018-09-28 | 2022-11-15 | Asahi Kasei Pharma Corporation | Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent |
CN109897900B (zh) * | 2019-03-13 | 2023-04-07 | 温州医科大学 | Epb42基因在肝癌sbrt疗效评估中的应用 |
CN112831560B (zh) * | 2019-11-23 | 2022-07-22 | 山东大学齐鲁医院 | γ-分泌酶激活蛋白基因和/或其编码的蛋白的新应用 |
CN112852964B (zh) * | 2021-03-08 | 2022-02-11 | 镇江市第一人民医院 | 一种环状RNA hsa_circ_0059707及其特异性扩增引物和应用 |
CN114712381B (zh) * | 2022-03-30 | 2024-04-26 | 浙江大学 | Ak2基因在制备白血病诱导分化治疗药物中的应用 |
CN115029383B (zh) * | 2022-04-21 | 2024-02-20 | 苏天生命科技(苏州)有限公司 | Ms4a3蛋白在调控红细胞成熟中的应用 |
CN117737251B (zh) * | 2024-02-21 | 2024-05-28 | 北京医院 | 一种aml诊断和预后的组合分子标志物 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7625697B2 (en) * | 1994-06-17 | 2009-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for constructing subarrays and subarrays made thereby |
US6647341B1 (en) * | 1999-04-09 | 2003-11-11 | Whitehead Institute For Biomedical Research | Methods for classifying samples and ascertaining previously unknown classes |
US20010044103A1 (en) * | 1999-12-03 | 2001-11-22 | Steeg Evan W. | Methods for the diagnosis and prognosis of acute leukemias |
US20040018513A1 (en) * | 2002-03-22 | 2004-01-29 | Downing James R | Classification and prognosis prediction of acute lymphoblastic leukemia by gene expression profiling |
WO2003102235A2 (en) * | 2002-05-31 | 2003-12-11 | Cancer Research Technology Limited | Specific genetic markets for cytogenetically defined acute myeloid leukaemia |
US20040152632A1 (en) * | 2002-11-06 | 2004-08-05 | Wyeth | Combination therapy for the treatment of acute leukemia and myelodysplastic syndrome |
AU2005214286A1 (en) * | 2004-02-23 | 2005-09-01 | Erasmus University Medical Center Rotterdam | Classification, diagnosis and prognosis of acute myeloid leukemia by gene expression profiling |
JP2005333987A (ja) * | 2004-05-06 | 2005-12-08 | Veridex Llc | 悪性血液疾患の予後 |
-
2006
- 2006-02-16 JP JP2007556371A patent/JP2008529557A/ja not_active Withdrawn
- 2006-02-16 BR BRPI0607753-6A patent/BRPI0607753A2/pt not_active IP Right Cessation
- 2006-02-16 KR KR1020077021244A patent/KR20070106027A/ko not_active Application Discontinuation
- 2006-02-16 MX MX2007009911A patent/MX2007009911A/es unknown
- 2006-02-16 CA CA002598025A patent/CA2598025A1/en not_active Abandoned
- 2006-02-16 US US11/884,169 patent/US20080280774A1/en not_active Abandoned
- 2006-02-16 AU AU2006214034A patent/AU2006214034A1/en not_active Abandoned
- 2006-02-16 EP EP06720889A patent/EP1848994A2/en not_active Ceased
- 2006-02-16 RU RU2007130722/15A patent/RU2007130722A/ru not_active Application Discontinuation
- 2006-02-16 CN CNA2006800119264A patent/CN101156067A/zh active Pending
- 2006-02-16 WO PCT/US2006/005855 patent/WO2006089233A2/en active Application Filing
-
2007
- 2007-08-08 NO NO20074104A patent/NO20074104L/no not_active Application Discontinuation
- 2007-08-09 IL IL185189A patent/IL185189A0/en unknown
- 2007-08-15 CR CR9315A patent/CR9315A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
RU2007130722A (ru) | 2009-03-27 |
MX2007009911A (es) | 2008-02-20 |
US20080280774A1 (en) | 2008-11-13 |
JP2008529557A (ja) | 2008-08-07 |
WO2006089233A2 (en) | 2006-08-24 |
WO2006089233A3 (en) | 2007-03-29 |
CR9315A (es) | 2008-01-21 |
CN101156067A (zh) | 2008-04-02 |
CA2598025A1 (en) | 2006-08-24 |
IL185189A0 (en) | 2007-12-03 |
KR20070106027A (ko) | 2007-10-31 |
BRPI0607753A2 (pt) | 2009-10-06 |
AU2006214034A1 (en) | 2006-08-24 |
EP1848994A2 (en) | 2007-10-31 |
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