NO20071515L - Lerkanidipinsalt - Google Patents
LerkanidipinsaltInfo
- Publication number
- NO20071515L NO20071515L NO20071515A NO20071515A NO20071515L NO 20071515 L NO20071515 L NO 20071515L NO 20071515 A NO20071515 A NO 20071515A NO 20071515 A NO20071515 A NO 20071515A NO 20071515 L NO20071515 L NO 20071515L
- Authority
- NO
- Norway
- Prior art keywords
- acids
- clerididipine
- acidic
- amorphous
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Oppfinnelsen angår nye addisjonssalter innbefattende lerkanidipin og et syremotion valgt fra gruppen bestående av: (i) uorganiske syrer, (ii) sulfonsyrer, (iii) monokarboksylisyrer, (iv) dikarboksylsyrer, (v) trikarboksylsyrer, og (vi) aromatiske sulfonimider, under forutsetning at syremotionet ikke er saltsyre. Spesielt er beskrevet både amorfe og krystallinske salter av lerkanidipin med benzensulfon og naftalen-1,5-disulfonsyrer, samt amorfe salter av lerkanidipin med flere andre syremotioner.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60414904P | 2004-08-24 | 2004-08-24 | |
PCT/EP2005/009043 WO2006021397A1 (en) | 2004-08-24 | 2005-08-22 | Lercanidipine salts |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20071515L true NO20071515L (no) | 2007-05-22 |
Family
ID=35159792
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20071515A NO20071515L (no) | 2004-08-24 | 2007-03-23 | Lerkanidipinsalt |
Country Status (19)
Country | Link |
---|---|
US (1) | US7683179B2 (no) |
EP (1) | EP1799644B1 (no) |
JP (1) | JP2008510754A (no) |
KR (1) | KR20070045351A (no) |
CN (1) | CN101048379A (no) |
AR (1) | AR050467A1 (no) |
AU (1) | AU2005276619B2 (no) |
BR (1) | BRPI0514606A (no) |
CA (1) | CA2575078A1 (no) |
EA (1) | EA011773B1 (no) |
ES (1) | ES2462921T3 (no) |
IL (1) | IL180905A0 (no) |
MX (1) | MX2007002141A (no) |
NO (1) | NO20071515L (no) |
NZ (1) | NZ553127A (no) |
PE (1) | PE20060629A1 (no) |
TW (1) | TW200613275A (no) |
WO (1) | WO2006021397A1 (no) |
ZA (1) | ZA200702364B (no) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ528216A (en) * | 2001-02-24 | 2006-12-22 | Boehringer Ingelheim Pharma | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions |
US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
US7501426B2 (en) | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
AR052918A1 (es) * | 2005-02-25 | 2007-04-11 | Recordati Ireland Ltd | Clorhidrato de lercanidipina amorfo |
AR053023A1 (es) * | 2005-02-25 | 2007-04-18 | Recordati Ireland Ltd | Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen |
DE102005035891A1 (de) * | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
EA030606B1 (ru) | 2006-05-04 | 2018-08-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Способы приготовления лекарственного средства, содержащего полиморфы |
JP2009540007A (ja) | 2006-06-12 | 2009-11-19 | ノバルティス アクチエンゲゼルシャフト | N−ヒドロキシ−3−[4−[[[2−(2−メチル−1h−インドール−3−イル)エチル]アミノ]メチル]フェニル]−2e−2−プロペンアミドの塩の製造方法 |
WO2008040367A1 (en) * | 2006-08-01 | 2008-04-10 | Union Quimico-Farmaceutica S.A. | Lercanidipine hydrobromide, a process for its preparation, crystalline forms and compositions thereof |
US20080175872A1 (en) * | 2006-09-28 | 2008-07-24 | Osmotica Corp. | Controlled Release Dosage Form Containing Lercanidipine and a Performance-enhancing Acid |
ES2306595B1 (es) * | 2007-02-09 | 2009-09-11 | Laboratorios Almirall S.A. | Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2. |
US20080234516A1 (en) * | 2007-03-14 | 2008-09-25 | Valerie Niddam-Hildesheim | Processes for preparing solid states of O-desmethylvenlafaxine succinate |
WO2009017813A1 (en) * | 2007-08-02 | 2009-02-05 | Teva Pharmaceutical Industries Ltd. | O-desmethyl venlafaxine saccharinate |
US8063250B2 (en) | 2007-11-26 | 2011-11-22 | Teva Pharmaceutical Industries, Ltd. | Crystal forms of O-desmethylvenlafaxine fumarate |
PE20140960A1 (es) | 2008-04-03 | 2014-08-15 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
AU2009276560B2 (en) * | 2008-08-01 | 2015-04-16 | Chiesi Farmaceutici S.P.A. | Pharmaceutical compositions and methods for producing low impurity concentrations of the same |
SI2320739T1 (sl) * | 2008-08-01 | 2020-03-31 | Chiesi Farmaceutici S.P.A. | Farmacevtski sestavki in postopki za njihovo stabiliziranje |
BRPI0916997A2 (pt) | 2008-08-06 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Inibidor de dpp-4 e seu uso |
UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
EP2344195A2 (en) | 2008-09-10 | 2011-07-20 | Boehringer Ingelheim International GmbH | Combination therapy for the treatment of diabetes and related conditions |
US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
BRPI0923121A2 (pt) | 2008-12-23 | 2015-08-11 | Boehringer Ingelheim Int | Formas salinas de compostos orgânico |
TW201036975A (en) | 2009-01-07 | 2010-10-16 | Boehringer Ingelheim Int | Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy |
ES2760917T3 (es) | 2009-11-27 | 2020-05-18 | Boehringer Ingelheim Int | Tratamiento de pacientes diabéticos genotipificados con inhibidores DPP-IV como la linagliptina |
CA2795023A1 (en) * | 2010-03-29 | 2011-10-06 | Pliva Hrvatska D.O.O. | Crystal forms of o-desmethylvenlafaxine fumarate |
JP6034781B2 (ja) | 2010-05-05 | 2016-11-30 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 併用療法 |
EA201991014A1 (ru) | 2010-06-24 | 2019-09-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Лечение диабета |
US9034883B2 (en) | 2010-11-15 | 2015-05-19 | Boehringer Ingelheim International Gmbh | Vasoprotective and cardioprotective antidiabetic therapy |
MX366629B (es) | 2011-07-15 | 2019-07-17 | Boehringer Ingelheim Int | Quinazolinas sustituidas, su preparación y su uso en composiciones farmacéuticas. |
US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
EP3685839A1 (en) | 2012-05-14 | 2020-07-29 | Boehringer Ingelheim International GmbH | Linagliptin for use in the treatment of albuminuria and kidney related diseases |
WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
US9526728B2 (en) | 2014-02-28 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Medical use of a DPP-4 inhibitor |
JP2019517542A (ja) | 2016-06-10 | 2019-06-24 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | リナグリプチンおよびメトホルミンの組合せ |
WO2023219106A1 (ja) * | 2022-05-10 | 2023-11-16 | Myrodia Therapeutics株式会社 | 2-メチル-2-チアゾリンの塩 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8403866D0 (en) | 1984-02-14 | 1984-03-21 | Recordati Chem Pharm | Diphenylalkylaminoalkyl esters |
IT1275532B (it) * | 1995-07-14 | 1997-08-07 | Recordati Chem Pharm | Uso di derivati 1,4-diidropiridinici per la prevenzione e la terapia della degenerazione aterosclerotica della parete arteriosa |
US5696139A (en) | 1995-05-12 | 1997-12-09 | Recordati S.A., Chemical And Pharmaceutical Company | Use of S-enantiomers of 1,4-dihydropyridine derivatives for treating heart failure |
US5912351A (en) | 1995-05-12 | 1999-06-15 | Recordati, S.A. Chemical And Pharmaceutical Company | Anhydrous 1,4-Dihydropyridines and salts thereof |
IT1301759B1 (it) * | 1998-06-19 | 2000-07-07 | Nicox Sa | Sali nitrati di farmaci antiipertensivi |
US20030069285A1 (en) | 2001-08-06 | 2003-04-10 | Recordati Ireland Limited | Novel solvate and crystalline forms of lercanidipine hydrochloride |
US6852737B2 (en) | 2001-08-06 | 2005-02-08 | Recordati Ireland Limited | Crude and crystalline forms of lercanidipine hydrochloride |
US6699892B2 (en) * | 2002-06-04 | 2004-03-02 | Yung Shin Pharmaceutical Industrial Co., Ltd. | Pharmaceutically acceptable salt of amlodipine and method of preparing the same |
JP2006504800A (ja) * | 2002-10-16 | 2006-02-09 | レコーダチ アイルランド リミテッド | リシノプリル/レルカニジピンの組み合わせ治療 |
US20040198789A1 (en) * | 2003-02-28 | 2004-10-07 | Recordati Ireland Limited | Lercanidipine/ARB/diuretic therapeutic combinations |
-
2005
- 2005-08-19 TW TW094128384A patent/TW200613275A/zh unknown
- 2005-08-22 NZ NZ553127A patent/NZ553127A/xx not_active IP Right Cessation
- 2005-08-22 BR BRPI0514606-2A patent/BRPI0514606A/pt not_active IP Right Cessation
- 2005-08-22 KR KR1020077006715A patent/KR20070045351A/ko not_active Application Discontinuation
- 2005-08-22 CA CA002575078A patent/CA2575078A1/en not_active Abandoned
- 2005-08-22 PE PE2005000963A patent/PE20060629A1/es not_active Application Discontinuation
- 2005-08-22 WO PCT/EP2005/009043 patent/WO2006021397A1/en active Application Filing
- 2005-08-22 EP EP05776228.8A patent/EP1799644B1/en active Active
- 2005-08-22 MX MX2007002141A patent/MX2007002141A/es not_active Application Discontinuation
- 2005-08-22 JP JP2007528715A patent/JP2008510754A/ja not_active Abandoned
- 2005-08-22 ES ES05776228.8T patent/ES2462921T3/es active Active
- 2005-08-22 CN CNA2005800284676A patent/CN101048379A/zh active Pending
- 2005-08-22 AU AU2005276619A patent/AU2005276619B2/en not_active Ceased
- 2005-08-22 AR ARP050103516A patent/AR050467A1/es not_active Application Discontinuation
- 2005-08-22 EA EA200700492A patent/EA011773B1/ru not_active IP Right Cessation
- 2005-08-24 US US11/211,769 patent/US7683179B2/en not_active Expired - Fee Related
-
2007
- 2007-01-23 IL IL180905A patent/IL180905A0/en unknown
- 2007-03-22 ZA ZA200702364A patent/ZA200702364B/xx unknown
- 2007-03-23 NO NO20071515A patent/NO20071515L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PE20060629A1 (es) | 2006-08-11 |
CN101048379A (zh) | 2007-10-03 |
EP1799644A1 (en) | 2007-06-27 |
EP1799644B1 (en) | 2014-02-12 |
CA2575078A1 (en) | 2006-03-02 |
WO2006021397A8 (en) | 2006-04-27 |
ZA200702364B (en) | 2008-09-25 |
EA200700492A1 (ru) | 2007-08-31 |
US20060047125A1 (en) | 2006-03-02 |
KR20070045351A (ko) | 2007-05-02 |
AU2005276619B2 (en) | 2009-04-30 |
AU2005276619A1 (en) | 2006-03-02 |
NZ553127A (en) | 2009-07-31 |
BRPI0514606A (pt) | 2008-06-17 |
MX2007002141A (es) | 2007-04-27 |
TW200613275A (en) | 2006-05-01 |
JP2008510754A (ja) | 2008-04-10 |
ES2462921T3 (es) | 2014-05-26 |
US7683179B2 (en) | 2010-03-23 |
IL180905A0 (en) | 2007-07-04 |
EA011773B1 (ru) | 2009-06-30 |
AR050467A1 (es) | 2006-10-25 |
WO2006021397A1 (en) | 2006-03-02 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |