NO20070865L - Fremgangsmate for fremstilling av 2'-deoksy-2',2'-difluorcytidin. - Google Patents
Fremgangsmate for fremstilling av 2'-deoksy-2',2'-difluorcytidin.Info
- Publication number
- NO20070865L NO20070865L NO20070865A NO20070865A NO20070865L NO 20070865 L NO20070865 L NO 20070865L NO 20070865 A NO20070865 A NO 20070865A NO 20070865 A NO20070865 A NO 20070865A NO 20070865 L NO20070865 L NO 20070865L
- Authority
- NO
- Norway
- Prior art keywords
- formula
- difluorocytidine
- deoxy
- preparation
- nucleoside
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20040116316 | 2004-12-30 | ||
PCT/KR2005/001954 WO2006070985A1 (fr) | 2004-12-30 | 2005-06-23 | Méthode de synthèse de la 2’-désoxy-2’,2’-difluorocytidine |
PCT/KR2005/004633 WO2006071090A1 (fr) | 2004-12-30 | 2005-12-29 | Methode servant a preparer 2'-deoxy-2',2'-difluorocytidine |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20070865L true NO20070865L (no) | 2007-04-24 |
Family
ID=36615168
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20070865A NO20070865L (no) | 2004-12-30 | 2007-02-15 | Fremgangsmate for fremstilling av 2'-deoksy-2',2'-difluorcytidin. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1831236A4 (fr) |
CN (1) | CN101010329B (fr) |
AU (1) | AU2005320374B2 (fr) |
BR (1) | BRPI0514718A (fr) |
NO (1) | NO20070865L (fr) |
WO (1) | WO2006071090A1 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602005019626D1 (de) * | 2005-03-04 | 2010-04-08 | Fresenius Kabi Oncology Ltd | Zwischenprodukt und verfahren zur herstellung von an beta-anomeren angereicherten 2'-desoxy,2',2'-difluor-d-ribufuranosylnukleosiden |
CN100475832C (zh) | 2007-05-31 | 2009-04-08 | 南京卡文迪许生物工程技术有限公司 | 一种新颖的高立体选择性合成吉西他滨工艺及中间体 |
CN101381387B (zh) * | 2007-09-06 | 2011-08-31 | 上海希迪制药有限公司 | 制备2'-脱氧-2',2'-二氟-β-胞苷盐酸盐的方法 |
KR20100102107A (ko) * | 2007-11-06 | 2010-09-20 | 파마이센시아 코퍼레이션 | β-뉴클레오시드의 새로운 합성 방법 |
CA2727813A1 (fr) * | 2008-06-12 | 2009-12-17 | Scinopharm Taiwan, Ltd. | Polymorphes cristallins de la base gemcitabine |
WO2010029574A2 (fr) * | 2008-08-18 | 2010-03-18 | Vishwanath Kannan | Procédé amélioré de préparation de gemcitabine et de ses intermédiaires au moyen de nouveaux groupes de protection et de résines échangeuses d'ions |
CN102617484B (zh) * | 2011-06-30 | 2014-05-14 | 江苏豪森药业股份有限公司 | 盐酸吉西他滨制备过程中胞嘧啶的回收处理方法 |
CN102617483B (zh) * | 2011-06-30 | 2013-04-24 | 江苏豪森药业股份有限公司 | 盐酸吉西他滨制备过程中胞嘧啶的回收处理方法 |
CN102432654A (zh) * | 2011-09-26 | 2012-05-02 | 宋云龙 | 吉西他滨酰胺衍生物及其制备方法和用途 |
CN103224541B (zh) * | 2013-04-27 | 2015-07-01 | 江苏豪森药业股份有限公司 | 吉西他滨α-异构体转化回收工艺 |
CN106317147B (zh) * | 2015-07-06 | 2018-11-27 | 扬州硒瑞恩生物医药科技有限公司 | 核苷类化合物及其制备方法 |
CN109305992A (zh) * | 2017-07-28 | 2019-02-05 | 江苏先声药业有限公司 | 一种阿扎胞苷的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5223608A (en) * | 1987-08-28 | 1993-06-29 | Eli Lilly And Company | Process for and intermediates of 2',2'-difluoronucleosides |
CA2098874C (fr) * | 1992-06-22 | 2004-04-20 | Ta-Sen Chou | Methode de glycosylation anionique stereoselective |
US5371210A (en) * | 1992-06-22 | 1994-12-06 | Eli Lilly And Company | Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides |
US5606048A (en) * | 1992-06-22 | 1997-02-25 | Eli Lilly And Company | Stereoselective glycosylation process for preparing 2'-Deoxy-2', 2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides |
US5401861A (en) * | 1992-06-22 | 1995-03-28 | Eli Lilly And Company | Low temperature process for preparing alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl sulfonates |
CN1228342C (zh) * | 2003-04-08 | 2005-11-23 | 深圳市汉德森技术有限公司 | 以1,6-脱水-β-D-葡萄糖为原料制备2'-脱氧-2',2'-二氟-β-核胞苷或其药用盐的方法 |
-
2005
- 2005-12-29 WO PCT/KR2005/004633 patent/WO2006071090A1/fr active Application Filing
- 2005-12-29 EP EP05823850.2A patent/EP1831236A4/fr not_active Withdrawn
- 2005-12-29 CN CN200580029086XA patent/CN101010329B/zh not_active Expired - Fee Related
- 2005-12-29 AU AU2005320374A patent/AU2005320374B2/en not_active Ceased
- 2005-12-29 BR BRPI0514718-2A patent/BRPI0514718A/pt not_active IP Right Cessation
-
2007
- 2007-02-15 NO NO20070865A patent/NO20070865L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2005320374A1 (en) | 2006-07-06 |
EP1831236A4 (fr) | 2013-11-20 |
CN101010329A (zh) | 2007-08-01 |
EP1831236A1 (fr) | 2007-09-12 |
AU2005320374B2 (en) | 2009-01-08 |
CN101010329B (zh) | 2011-06-08 |
BRPI0514718A (pt) | 2008-07-01 |
WO2006071090A1 (fr) | 2006-07-06 |
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Legal Events
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Representative=s name: TANDBERGS PATENTKONTOR AS, POSTBOKS |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |